Click here to switch to the map view.

The map label for this gene is ffh [H]

Identifier: 123966680

GI number: 123966680

Start: 1280458

End: 1281936

Strand: Reverse

Name: ffh [H]

Synonym: P9515_14471

Alternate gene names: 123966680

Gene position: 1281936-1280458 (Counterclockwise)

Preceding gene: 123966681

Following gene: 123966679

Centisome position: 75.22

GC content: 35.84

Gene sequence:

>1479_bases
ATGTTTGATGAACTCTCTTCACGCTTTGAAGACGCTGTTAAGGGTTTAAGAGGTGAAGCAAAAATTAGTGAAAATAATAT
TGATGATGCTTTAAAGCAAGTTAAAAAAGCATTATTAGATGCTGATGTTAGTTTATCGGTAGTAAAGGAATTTGTTTCAG
ATGTAAAAGACAAAGCTATTGGAGAAGATGTTGTAAGAGGTGTTAATCCTGGGCAGAAATTTATAGAGGTAGTCAATAAA
GAATTAATAAATGTAATGGGGAATGAGAATTCCCCGTTATTCGAAAAAGAGACCCCTCCTACAGTTATTTTGATGGCAGG
TTTACAAGGTGCTGGTAAAACAACAGCAACAGGTAAATTAGGCCTTTATTTGAAGGAAAAGGAAAAAAAGGTTTTATTAG
TAGCAGCTGATATCTATAGACCTGCAGCTGTTGAACAACTTAAGACCATTGGTAATCAATACGATTTAGAAGTTTTCTCA
GCGAAAGAAAAAGATAGTAAGCCTGAAGAAATTGCGAAGGATGCTTTGATTTATGCCAATGAAAATAATGTAGATACCTT
AATTGTTGATACTGCAGGAAGATTACAAATAGATGAATTAATGATGAGTGAAATGGTTCGAATAAAAGAAGTTACAAATC
CAGATGAAGTTTTACTGGTTGTAGATTCTATGATTGGACAAGAAGCTGCTGATTTGACAAAGTCATTTCATGAAAAAGTT
GGAATATCGGGAGCAATATTAACTAAGTTAGATGGTGATTCAAGAGGTGGCGCAGCGCTTTCAATAAGAAAAATAAGTGG
AAAACCCATAAAATTTATCGGAACTGGTGAAAAGATAGAAGCATTGCAGCCATTTCATCCTGAGAGAATGGCAAGCAGAA
TCCTTGGTATGGGGGATGTATTAACACTTGTTGAAAAGGCACAAAAAGAAGTTGAACTTGCGGATGCAGAGGTAATGCAA
AAGAAACTTCAAGAAGCAACTTTTGACTTTAATGATTTTGTTAAACAAATGAGATTAATGAAGAGAATGGGATCTCTTGG
AGGATTAATAAAATTAATACCGGGGATGAATAAAATTGATGATGGAATGATAAAAAATGGAGAAGAACAACTAAAAAAAA
TTGAATCAATGATTTCATCTATGACTTTAGAAGAGAAGCAAAAGCCAGAAGTCCTTGCTGCACAACCATCTAGAAGACAA
AGAATTGCTCAAGGTAGCGGATATCAAGCAAAAGATGTGGATAAAGTACTTGCTGATTTTCAAAGAATGAGAGGTTTTAT
GAAACAAATGTCAAACGGAGGAATGCCCGGAATGGGAGGAATGCCCGGAATGGGAGGAATGCCCGGAATGGGAGGAATGC
CCGGAATGGGAGGAATGCCCGGAATGGGAGGAATGCCCGGAATGGGAGGAGGGAATAGTAATAAATTTTCAAAAAAGCAA
AAATCTAATAAAAAGAAAAAAGGTTTTGGGGATTTGTAA

Upstream 100 bases:

>100_bases
GTTTCTCAAATAACTCATGGAAATTAGTTGATTACATAAGCGGAGTTTAGGATTAGCTTTTAGTATCATCTATAATGTTC
ATATAAATCACGTATAACTA

Downstream 100 bases:

>100_bases
TTTCTAAATAGCTACCTTTAAATGATATTATTAAATATATCTCTAATAATTTAAAATGATTAAATTGCGCCTTAAGCGCT
TTGGAAAGAAAAAAGAAGCA

Product: signal recognition particle protein (SRP54)

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MFDELSSRFEDAVKGLRGEAKISENNIDDALKQVKKALLDADVSLSVVKEFVSDVKDKAIGEDVVRGVNPGQKFIEVVNK
ELINVMGNENSPLFEKETPPTVILMAGLQGAGKTTATGKLGLYLKEKEKKVLLVAADIYRPAAVEQLKTIGNQYDLEVFS
AKEKDSKPEEIAKDALIYANENNVDTLIVDTAGRLQIDELMMSEMVRIKEVTNPDEVLLVVDSMIGQEAADLTKSFHEKV
GISGAILTKLDGDSRGGAALSIRKISGKPIKFIGTGEKIEALQPFHPERMASRILGMGDVLTLVEKAQKEVELADAEVMQ
KKLQEATFDFNDFVKQMRLMKRMGSLGGLIKLIPGMNKIDDGMIKNGEEQLKKIESMISSMTLEEKQKPEVLAAQPSRRQ
RIAQGSGYQAKDVDKVLADFQRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGGNSNKFSKKQ
KSNKKKKGFGDL

Sequences:

>Translated_492_residues
MFDELSSRFEDAVKGLRGEAKISENNIDDALKQVKKALLDADVSLSVVKEFVSDVKDKAIGEDVVRGVNPGQKFIEVVNK
ELINVMGNENSPLFEKETPPTVILMAGLQGAGKTTATGKLGLYLKEKEKKVLLVAADIYRPAAVEQLKTIGNQYDLEVFS
AKEKDSKPEEIAKDALIYANENNVDTLIVDTAGRLQIDELMMSEMVRIKEVTNPDEVLLVVDSMIGQEAADLTKSFHEKV
GISGAILTKLDGDSRGGAALSIRKISGKPIKFIGTGEKIEALQPFHPERMASRILGMGDVLTLVEKAQKEVELADAEVMQ
KKLQEATFDFNDFVKQMRLMKRMGSLGGLIKLIPGMNKIDDGMIKNGEEQLKKIESMISSMTLEEKQKPEVLAAQPSRRQ
RIAQGSGYQAKDVDKVLADFQRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGGNSNKFSKKQ
KSNKKKKGFGDL
>Mature_492_residues
MFDELSSRFEDAVKGLRGEAKISENNIDDALKQVKKALLDADVSLSVVKEFVSDVKDKAIGEDVVRGVNPGQKFIEVVNK
ELINVMGNENSPLFEKETPPTVILMAGLQGAGKTTATGKLGLYLKEKEKKVLLVAADIYRPAAVEQLKTIGNQYDLEVFS
AKEKDSKPEEIAKDALIYANENNVDTLIVDTAGRLQIDELMMSEMVRIKEVTNPDEVLLVVDSMIGQEAADLTKSFHEKV
GISGAILTKLDGDSRGGAALSIRKISGKPIKFIGTGEKIEALQPFHPERMASRILGMGDVLTLVEKAQKEVELADAEVMQ
KKLQEATFDFNDFVKQMRLMKRMGSLGGLIKLIPGMNKIDDGMIKNGEEQLKKIESMISSMTLEEKQKPEVLAAQPSRRQ
RIAQGSGYQAKDVDKVLADFQRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGGNSNKFSKKQ
KSNKKKKGFGDL

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=510, Percent_Identity=31.9607843137255, Blast_Score=238, Evalue=9e-63,
Organism=Homo sapiens, GI226371618, Length=389, Percent_Identity=33.6760925449871, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI89061728, Length=168, Percent_Identity=36.9047619047619, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI23308697, Length=326, Percent_Identity=25.4601226993865, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI295424842, Length=326, Percent_Identity=25.4601226993865, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1788963, Length=427, Percent_Identity=48.711943793911, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1789874, Length=215, Percent_Identity=40, Blast_Score=151, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17539958, Length=435, Percent_Identity=29.4252873563218, Blast_Score=212, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI193206261, Length=295, Percent_Identity=29.4915254237288, Blast_Score=119, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=454, Percent_Identity=33.7004405286344, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6320498, Length=220, Percent_Identity=29.0909090909091, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17647949, Length=443, Percent_Identity=30.9255079006772, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24641198, Length=316, Percent_Identity=27.8481012658228, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 53430; Mature: 53430

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDELSSRFEDAVKGLRGEAKISENNIDDALKQVKKALLDADVSLSVVKEFVSDVKDKAI
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GEDVVRGVNPGQKFIEVVNKELINVMGNENSPLFEKETPPTVILMAGLQGAGKTTATGKL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCE
GLYLKEKEKKVLLVAADIYRPAAVEQLKTIGNQYDLEVFSAKEKDSKPEEIAKDALIYAN
EEEEECCCCEEEEEEHHHHCHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHCCEEEEC
ENNVDTLIVDTAGRLQIDELMMSEMVRIKEVTNPDEVLLVVDSMIGQEAADLTKSFHEKV
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHCHHHHHHHHHHHHHH
GISGAILTKLDGDSRGGAALSIRKISGKPIKFIGTGEKIEALQPFHPERMASRILGMGDV
CCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHCCCCCHHHHHHHHHCCHHH
LTLVEKAQKEVELADAEVMQKKLQEATFDFNDFVKQMRLMKRMGSLGGLIKLIPGMNKID
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
DGMIKNGEEQLKKIESMISSMTLEEKQKPEVLAAQPSRRQRIAQGSGYQAKDVDKVLADF
CHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCCHHHHHHHHHHH
QRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGGNSNKFSKKQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
KSNKKKKGFGDL
HHCHHCCCCCCC
>Mature Secondary Structure
MFDELSSRFEDAVKGLRGEAKISENNIDDALKQVKKALLDADVSLSVVKEFVSDVKDKAI
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GEDVVRGVNPGQKFIEVVNKELINVMGNENSPLFEKETPPTVILMAGLQGAGKTTATGKL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCE
GLYLKEKEKKVLLVAADIYRPAAVEQLKTIGNQYDLEVFSAKEKDSKPEEIAKDALIYAN
EEEEECCCCEEEEEEHHHHCHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHCCEEEEC
ENNVDTLIVDTAGRLQIDELMMSEMVRIKEVTNPDEVLLVVDSMIGQEAADLTKSFHEKV
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHCHHHHHHHHHHHHHH
GISGAILTKLDGDSRGGAALSIRKISGKPIKFIGTGEKIEALQPFHPERMASRILGMGDV
CCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHCCCCCHHHHHHHHHCCHHH
LTLVEKAQKEVELADAEVMQKKLQEATFDFNDFVKQMRLMKRMGSLGGLIKLIPGMNKID
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
DGMIKNGEEQLKKIESMISSMTLEEKQKPEVLAAQPSRRQRIAQGSGYQAKDVDKVLADF
CHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCCHHHHHHHHHHH
QRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGGNSNKFSKKQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
KSNKKKKGFGDL
HHCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]