| Definition | Prochlorococcus marinus str. MIT 9515, complete genome. |
|---|---|
| Accession | NC_008817 |
| Length | 1,704,176 |
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The map label for this gene is pnp [H]
Identifier: 123966596
GI number: 123966596
Start: 1195222
End: 1197387
Strand: Direct
Name: pnp [H]
Synonym: P9515_13631
Alternate gene names: 123966596
Gene position: 1195222-1197387 (Clockwise)
Preceding gene: 123966595
Following gene: 123966598
Centisome position: 70.13
GC content: 38.09
Gene sequence:
>2166_bases GTGGAAGGAAAAAATACGTCGATCACGTTTGACGGACGAGAGATACGACTAACTACAGGACTATATGCTCCTCAAGCAAA TGGAGCCGTAATGATTGAATGTGGTGACACATCTTTATTAGTTACTGCAACAAAAACAAATAAGAAAGAAGCTGCAGACT TTCTCCCTCTAATATGTGATTACGAGGAGAAATTATATGCTGCAGGAAGAATTCCTGGTGGTTTCATGAGAAGAGAAGGC AGGCCTCCTGAAAGAGCCACTTTAATAGCAAGATTAATAGATAGGCCAATGAGGCCCCTTTTTCCAATATGGATGAGAGA TGAGATACAAATAGTTGCTTCTTGCCTTTCACTTGATGAAAGAGTACCTGCTGATGTATTAGCGGTGACTGGAGCATCTC TAGCAACATTATTAGGAGAAATCCCATTTTACGGACCAATGGCTGCCGTGAGAGTTGGATTATTAGGAGATGATTTCATC TTAAATCCAAGTTATAGAGAAATCGAGAAAGGTGATCTTGATATTATTGTCGCAGGGTCCCCTGAAGGAATTGTGATGAT TGAAGCAGGTGCAAATCAACTTTCAGAGCAGGATACGATCGAAGCAATAGATTTCGGATACGAGGCAGTAACCGAACTTA TCAAAGCTCAAGAAAATCTTCTTAAGGACTTAGGTATTAAACAAGTTAAACCTTCAGAACCAGAAGTAGATAATACTTTA GCTGCATATTTAGAGAAAAACTGCACAAAACCTATTGATTTAGTTTTAAAGAAATTTGATCAATCTAAAGAAGAAAGAGA TTTGGAATTAGAAAAAATAAAGCTTGAAGTTCATAGCAAAATCGATTCCCTTAAAGATGACAATCAATTAAAGGTTCTAA CTTCAGAAAATGAAAAATTAATTCATTCTGATTTTAAAAAACTAACCAAAAAGTTAATGAGGTCTCAAATCATTAATGAT GGTAAAAGAGTCGATGGAAGAGATCTTGACGAAGTTAGAAAGATATCGGCAAAAGCAGGAATACTCCCTAAAAGAGTTCA TGGATCTGCCGTATTCCAAAGAGGTCTTACTCAAGTTTTATCAACTACTACACTTGGAACTCCAAGTGACGCACAAGAAA TGGATGATTTAAATCCTAGTACTGAGAAAACCTATTTACATCACTACAATTTTCCACCTTACTCCGTTGGAGAAACGAGA CCTATGAGAACCCCTGGGAGAAGAGAGATCGGCCATGGGGCTTTAGCAGAAAGAGCAATAATTCCAGTACTCCCAGGGAA GGAAACATTCCCGTATGTTTTAAGAGTAGTTAGCGAAGTATTAAGCTCTAATGGTTCAACCTCAATGGGATCTGTTTGCG GCAGTACACTTTCGTTATTAGATGCTGGTGTTCCATTGAAAGCTCCCGTAAGTGGAACTGCTATGGGTTTAATTAAAGAA GGTAAAGAAGTTCGGATACTTACTGATATTCAGGGAATTGAAGATTTTCTTGGAGATATGGATTTCAAAGTTGCTGGAAC TGAAAAAGGAATCACTGCATTACAAATGGATATGAAAATTACAGGATTACCAGTTTCTATAATTTCCGATGCAATAAAAA AAGCTCGCCCAGCAAGACTGCATATTTTAGAAAAAATGCAAGATGCAATTGATAAACCTCAAGAATCATTATCACCTCAT GCTCCAAGACTTTTAAGTTTCAGGATTGATCCCGAGCTTATCGGAACAGTTATTGGACCGGGAGGTAGAACTATCAAAGG TATTACTGAAAGGACTAATACCAAAATAGATATTGAAGATGGAGGAATTGTAACTATTGCTTCTCATGATGGAGCGGCTG CTGAAGAAGCTCAAAAAATAATAGAGGGCTTAACACGAAAAGTCCATGAAGGAGAGATCTTCTCAGGAGTAGTAACCAGA ATTATTCCAATAGGAGCATTTGTAGAAATTCTTCCTGGGAAAGAAGGCATGGTTCACATTTCGCAATTATCTGAGGCTAG AGTTGAAAGAGTTGAAGATGTTGTAAGGCAAGGAGATGAAGTAACTGTCAGAGTAAGAGAAATTGATAGCAGAGGTAGAA TTAACCTTACATTAAGAGGGGTTGCACAAAATGGCGGGATGTCTTACCCAGAACCGACTCCTACTCCAGTAGCTCCACTT AACTAA
Upstream 100 bases:
>100_bases GGTAATCAAAAAATTATTTTAAAACCTTATCTAAATAATTTACTCAATATGTCCCTACGAGATGTAAGAATAAATTGTGT ATAGATTTATAATTTAAAAA
Downstream 100 bases:
>100_bases GTTATAAAAGGGTAAATATCATATTTTTTAATTATTTCTTTTATCTGAAAACAAATTTTTGAGTGCATATTTTTATTATT TGAGGCAATAATTATACCTG
Product: polynucleotide phosphorylase/polyadenylase
Products: NA
Alternate protein names: Polynucleotide phosphorylase; PNPase [H]
Number of amino acids: Translated: 721; Mature: 721
Protein sequence:
>721_residues MEGKNTSITFDGREIRLTTGLYAPQANGAVMIECGDTSLLVTATKTNKKEAADFLPLICDYEEKLYAAGRIPGGFMRREG RPPERATLIARLIDRPMRPLFPIWMRDEIQIVASCLSLDERVPADVLAVTGASLATLLGEIPFYGPMAAVRVGLLGDDFI LNPSYREIEKGDLDIIVAGSPEGIVMIEAGANQLSEQDTIEAIDFGYEAVTELIKAQENLLKDLGIKQVKPSEPEVDNTL AAYLEKNCTKPIDLVLKKFDQSKEERDLELEKIKLEVHSKIDSLKDDNQLKVLTSENEKLIHSDFKKLTKKLMRSQIIND GKRVDGRDLDEVRKISAKAGILPKRVHGSAVFQRGLTQVLSTTTLGTPSDAQEMDDLNPSTEKTYLHHYNFPPYSVGETR PMRTPGRREIGHGALAERAIIPVLPGKETFPYVLRVVSEVLSSNGSTSMGSVCGSTLSLLDAGVPLKAPVSGTAMGLIKE GKEVRILTDIQGIEDFLGDMDFKVAGTEKGITALQMDMKITGLPVSIISDAIKKARPARLHILEKMQDAIDKPQESLSPH APRLLSFRIDPELIGTVIGPGGRTIKGITERTNTKIDIEDGGIVTIASHDGAAAEEAQKIIEGLTRKVHEGEIFSGVVTR IIPIGAFVEILPGKEGMVHISQLSEARVERVEDVVRQGDEVTVRVREIDSRGRINLTLRGVAQNGGMSYPEPTPTPVAPL N
Sequences:
>Translated_721_residues MEGKNTSITFDGREIRLTTGLYAPQANGAVMIECGDTSLLVTATKTNKKEAADFLPLICDYEEKLYAAGRIPGGFMRREG RPPERATLIARLIDRPMRPLFPIWMRDEIQIVASCLSLDERVPADVLAVTGASLATLLGEIPFYGPMAAVRVGLLGDDFI LNPSYREIEKGDLDIIVAGSPEGIVMIEAGANQLSEQDTIEAIDFGYEAVTELIKAQENLLKDLGIKQVKPSEPEVDNTL AAYLEKNCTKPIDLVLKKFDQSKEERDLELEKIKLEVHSKIDSLKDDNQLKVLTSENEKLIHSDFKKLTKKLMRSQIIND GKRVDGRDLDEVRKISAKAGILPKRVHGSAVFQRGLTQVLSTTTLGTPSDAQEMDDLNPSTEKTYLHHYNFPPYSVGETR PMRTPGRREIGHGALAERAIIPVLPGKETFPYVLRVVSEVLSSNGSTSMGSVCGSTLSLLDAGVPLKAPVSGTAMGLIKE GKEVRILTDIQGIEDFLGDMDFKVAGTEKGITALQMDMKITGLPVSIISDAIKKARPARLHILEKMQDAIDKPQESLSPH APRLLSFRIDPELIGTVIGPGGRTIKGITERTNTKIDIEDGGIVTIASHDGAAAEEAQKIIEGLTRKVHEGEIFSGVVTR IIPIGAFVEILPGKEGMVHISQLSEARVERVEDVVRQGDEVTVRVREIDSRGRINLTLRGVAQNGGMSYPEPTPTPVAPL N >Mature_721_residues MEGKNTSITFDGREIRLTTGLYAPQANGAVMIECGDTSLLVTATKTNKKEAADFLPLICDYEEKLYAAGRIPGGFMRREG RPPERATLIARLIDRPMRPLFPIWMRDEIQIVASCLSLDERVPADVLAVTGASLATLLGEIPFYGPMAAVRVGLLGDDFI LNPSYREIEKGDLDIIVAGSPEGIVMIEAGANQLSEQDTIEAIDFGYEAVTELIKAQENLLKDLGIKQVKPSEPEVDNTL AAYLEKNCTKPIDLVLKKFDQSKEERDLELEKIKLEVHSKIDSLKDDNQLKVLTSENEKLIHSDFKKLTKKLMRSQIIND GKRVDGRDLDEVRKISAKAGILPKRVHGSAVFQRGLTQVLSTTTLGTPSDAQEMDDLNPSTEKTYLHHYNFPPYSVGETR PMRTPGRREIGHGALAERAIIPVLPGKETFPYVLRVVSEVLSSNGSTSMGSVCGSTLSLLDAGVPLKAPVSGTAMGLIKE GKEVRILTDIQGIEDFLGDMDFKVAGTEKGITALQMDMKITGLPVSIISDAIKKARPARLHILEKMQDAIDKPQESLSPH APRLLSFRIDPELIGTVIGPGGRTIKGITERTNTKIDIEDGGIVTIASHDGAAAEEAQKIIEGLTRKVHEGEIFSGVVTR IIPIGAFVEILPGKEGMVHISQLSEARVERVEDVVRQGDEVTVRVREIDSRGRINLTLRGVAQNGGMSYPEPTPTPVAPL N
Specific function: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction [H]
COG id: COG1185
COG function: function code J; Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 S1 motif domain [H]
Homologues:
Organism=Homo sapiens, GI188528628, Length=744, Percent_Identity=34.8118279569892, Blast_Score=434, Evalue=1e-121, Organism=Escherichia coli, GI145693187, Length=692, Percent_Identity=45.9537572254335, Blast_Score=597, Evalue=1e-171, Organism=Caenorhabditis elegans, GI115534063, Length=679, Percent_Identity=34.020618556701, Blast_Score=351, Evalue=6e-97, Organism=Drosophila melanogaster, GI281362905, Length=691, Percent_Identity=37.0477568740955, Blast_Score=433, Evalue=1e-121, Organism=Drosophila melanogaster, GI24651641, Length=691, Percent_Identity=37.0477568740955, Blast_Score=433, Evalue=1e-121, Organism=Drosophila melanogaster, GI24651643, Length=691, Percent_Identity=37.0477568740955, Blast_Score=433, Evalue=1e-121, Organism=Drosophila melanogaster, GI161079377, Length=625, Percent_Identity=37.28, Blast_Score=398, Evalue=1e-111,
Paralogues:
None
Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1000 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 3328 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001247 - InterPro: IPR015847 - InterPro: IPR004087 - InterPro: IPR004088 - InterPro: IPR018111 - InterPro: IPR012340 - InterPro: IPR016027 - InterPro: IPR012162 - InterPro: IPR015848 - InterPro: IPR003029 - InterPro: IPR020568 - InterPro: IPR022967 [H]
Pfam domain/function: PF00013 KH_1; PF03726 PNPase; PF01138 RNase_PH; PF03725 RNase_PH_C; PF00575 S1 [H]
EC number: =2.7.7.8 [H]
Molecular weight: Translated: 78734; Mature: 78734
Theoretical pI: Translated: 5.28; Mature: 5.28
Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEGKNTSITFDGREIRLTTGLYAPQANGAVMIECGDTSLLVTATKTNKKEAADFLPLICD CCCCCCEEEECCCEEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHCC YEEKLYAAGRIPGGFMRREGRPPERATLIARLIDRPMRPLFPIWMRDEIQIVASCLSLDE CHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHCHHHHHHHHHHHHHHH RVPADVLAVTGASLATLLGEIPFYGPMAAVRVGLLGDDFILNPSYREIEKGDLDIIVAGS CCCHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECCCHHHHCCCCEEEEEECC PEGIVMIEAGANQLSEQDTIEAIDFGYEAVTELIKAQENLLKDLGIKQVKPSEPEVDNTL CCCEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH AAYLEKNCTKPIDLVLKKFDQSKEERDLELEKIKLEVHSKIDSLKDDNQLKVLTSENEKL HHHHHHCCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCHH IHSDFKKLTKKLMRSQIINDGKRVDGRDLDEVRKISAKAGILPKRVHGSAVFQRGLTQVL HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH STTTLGTPSDAQEMDDLNPSTEKTYLHHYNFPPYSVGETRPMRTPGRREIGHGALAERAI HHCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCE IPVLPGKETFPYVLRVVSEVLSSNGSTSMGSVCGSTLSLLDAGVPLKAPVSGTAMGLIKE EECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHC GKEVRILTDIQGIEDFLGDMDFKVAGTEKGITALQMDMKITGLPVSIISDAIKKARPARL CCEEEEEEHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCHHH HILEKMQDAIDKPQESLSPHAPRLLSFRIDPELIGTVIGPGGRTIKGITERTNTKIDIED HHHHHHHHHHCCCHHHCCCCCCCEEEEEECHHHHHEEECCCCCEEECHHHCCCCEEEECC GGIVTIASHDGAAAEEAQKIIEGLTRKVHEGEIFSGVVTRIIPIGAFVEILPGKEGMVHI CCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCEEEH SQLSEARVERVEDVVRQGDEVTVRVREIDSRGRINLTLRGVAQNGGMSYPEPTPTPVAPL HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCC N C >Mature Secondary Structure MEGKNTSITFDGREIRLTTGLYAPQANGAVMIECGDTSLLVTATKTNKKEAADFLPLICD CCCCCCEEEECCCEEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHCC YEEKLYAAGRIPGGFMRREGRPPERATLIARLIDRPMRPLFPIWMRDEIQIVASCLSLDE CHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHCHHHHHHHHHHHHHHH RVPADVLAVTGASLATLLGEIPFYGPMAAVRVGLLGDDFILNPSYREIEKGDLDIIVAGS CCCHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECCCHHHHCCCCEEEEEECC PEGIVMIEAGANQLSEQDTIEAIDFGYEAVTELIKAQENLLKDLGIKQVKPSEPEVDNTL CCCEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH AAYLEKNCTKPIDLVLKKFDQSKEERDLELEKIKLEVHSKIDSLKDDNQLKVLTSENEKL HHHHHHCCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCHH IHSDFKKLTKKLMRSQIINDGKRVDGRDLDEVRKISAKAGILPKRVHGSAVFQRGLTQVL HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH STTTLGTPSDAQEMDDLNPSTEKTYLHHYNFPPYSVGETRPMRTPGRREIGHGALAERAI HHCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCE IPVLPGKETFPYVLRVVSEVLSSNGSTSMGSVCGSTLSLLDAGVPLKAPVSGTAMGLIKE EECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHC GKEVRILTDIQGIEDFLGDMDFKVAGTEKGITALQMDMKITGLPVSIISDAIKKARPARL CCEEEEEEHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCHHH HILEKMQDAIDKPQESLSPHAPRLLSFRIDPELIGTVIGPGGRTIKGITERTNTKIDIED HHHHHHHHHHCCCHHHCCCCCCCEEEEEECHHHHHEEECCCCCEEECHHHCCCCEEEECC GGIVTIASHDGAAAEEAQKIIEGLTRKVHEGEIFSGVVTRIIPIGAFVEILPGKEGMVHI CCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCEEEH SQLSEARVERVEDVVRQGDEVTVRVREIDSRGRINLTLRGVAQNGGMSYPEPTPTPVAPL HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCC N C
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA