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The map label for this gene is ctaD [H]

Identifier: 123966497

GI number: 123966497

Start: 1109626

End: 1111317

Strand: Direct

Name: ctaD [H]

Synonym: P9515_12641

Alternate gene names: 123966497

Gene position: 1109626-1111317 (Clockwise)

Preceding gene: 123966496

Following gene: 123966498

Centisome position: 65.11

GC content: 35.58

Gene sequence:

>1692_bases
ATGACAATTGTTAATTATGATCCAAGATTAGTTAAAACTAAAAATCCCTATCCCAAAGGGCCCAATGATTGGAAAAGGTT
TTTTAGTTTTAATACGGATGCAAAAGTAATTGGCATTCAATATATTGTCACAGCTCTTTTTTTCTTATTAATAGGTGGTC
TTTTAGGGATGTTGATTAGAGGAGAGTTAATAACACCACCATCAGATCTTTTTGATCCAACCGTTTACAACGGTCTGTAC
ACTATGCACGGAACAATCATGCTTTTTTTGTTCCTATTCCCTATTTTAAGTGGTTTAACAAATTTACTTGTACCTCCCAT
GATAGGAGCGCCAGATATGGCTTTCCCAAAACTTAATGCCTTAGCATTTTGGCTAGTCCCAGTTTTCTCAATAATACTTC
TTTTAAGTTTTTTTGTTCCTGGAGGGCCGGCCTCTTCAGGTTGGTGGTCATATCCCCCTATAAGTATTCAAAATCCTCTT
GGAAAAATAATAAATGGGGAAATGTTATGGATAATAGCAATATCTTTATCTGGGATTTCTTCGATCATTGGTGCTGTCAA
CTTTGTCACAACAATAATAAGAATGCGAGCCCCTGGGATGGGATTTTTCAAGATGCCAATTTTTATTTGGACTGTATTAG
CAGCTCAATTATTACAATTACTTGGATTACCTGCCTTAACTGGTGGAGCGATAATGTTATTTTTTGATCTAACATTTGGA
ACAAGTTTTTTCAGAGTTGAGGGGGGAGGAGACCCTGTTTTGTTTCAGCATTTTTTCTGGTTTTATTCTCATCCTGCCGT
CTATGTGATGGTTTTACCTGTATTTGGAATATTTTCTGAACTTTTTCCTGTTTATTCCAGAAAACCTCTTTTTGGATATA
AATTTGTTGCTATCGCTTCTTTTGGTATAACTATTCTTTCATTAGTTGTTTGGGTTCATCACATGTTCTATACAGGCACA
CCAATGTGGATGAGAAATTTATTTATGTTTACTACTATGCTCATTGCTGTGCCTACAGGTGTAAAAGTATTTGCCTGGAT
AGCTACATTATGGGGCGGAAATATTAGGTTAAGTACACCCATGCTTTTTTGTTTGGGGGGATTATTTAATTTTATTTTTG
GAGGAATCACTGGCGTAATGCTTGCAACAGTGCCAGTAGACATTCATGTTGGAAATACATATTTTGTTGTTGCTCATTTT
CACTATATTATTTTTAATACCATTGCTTTTGGAATATTTGCAGCTATTTATCACTGGTTCCCAAAATTTACTGGAAAGAT
GTTTTATGAAGGTTTAGGAAAAATTCATTTTACTCTTACTTTTATAGGAGCGACTTTAAATTGGTTACCGCTTCATTGGG
CTGGTTTATTAGGAATGCCGAGAAGAGTTGCCTCTTATGATCCTGAATTTGCAATTTGGAATGTACTAGCAAGTATTGGA
GCTTTTATTCTTGGAGTTGCCTCTATTCCTTTTATTTTAAATATGGTTAGTTCATGGGTTAGAGGTAAATCAGCTCCCCC
AAATCCTTGGAAAGCTATAGGGCTAGAGTGGCTACTCCCCTCTCCTCCGCCTCACGAAAATTTTGAAGAAGATATTCCAA
CGGTTTTAAATGAACCTTATTGTTATGGCTTAGATAAACCATTCGTCGAAGATGAGAAATTTTATGTAGAAAAGTCACTC
AAAAAACATTAA

Upstream 100 bases:

>100_bases
GAAATGGTAATAGAGGTTGGGCGACAGTTAAACCTGCTCCTGATCCAAAAGTTAATGAGGTGGGTTTTGAAGAAAGACCC
CATGATAGTTGAAATTTCCT

Downstream 100 bases:

>100_bases
AAAATGGTTTCAAAAAATCAAACTCTAACCTTAAATCATAAACCAGGCCATATTAAACATGATGGTCATAATATGACTGG
ATTTATAATATTTTTATGCT

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MTIVNYDPRLVKTKNPYPKGPNDWKRFFSFNTDAKVIGIQYIVTALFFLLIGGLLGMLIRGELITPPSDLFDPTVYNGLY
TMHGTIMLFLFLFPILSGLTNLLVPPMIGAPDMAFPKLNALAFWLVPVFSIILLLSFFVPGGPASSGWWSYPPISIQNPL
GKIINGEMLWIIAISLSGISSIIGAVNFVTTIIRMRAPGMGFFKMPIFIWTVLAAQLLQLLGLPALTGGAIMLFFDLTFG
TSFFRVEGGGDPVLFQHFFWFYSHPAVYVMVLPVFGIFSELFPVYSRKPLFGYKFVAIASFGITILSLVVWVHHMFYTGT
PMWMRNLFMFTTMLIAVPTGVKVFAWIATLWGGNIRLSTPMLFCLGGLFNFIFGGITGVMLATVPVDIHVGNTYFVVAHF
HYIIFNTIAFGIFAAIYHWFPKFTGKMFYEGLGKIHFTLTFIGATLNWLPLHWAGLLGMPRRVASYDPEFAIWNVLASIG
AFILGVASIPFILNMVSSWVRGKSAPPNPWKAIGLEWLLPSPPPHENFEEDIPTVLNEPYCYGLDKPFVEDEKFYVEKSL
KKH

Sequences:

>Translated_563_residues
MTIVNYDPRLVKTKNPYPKGPNDWKRFFSFNTDAKVIGIQYIVTALFFLLIGGLLGMLIRGELITPPSDLFDPTVYNGLY
TMHGTIMLFLFLFPILSGLTNLLVPPMIGAPDMAFPKLNALAFWLVPVFSIILLLSFFVPGGPASSGWWSYPPISIQNPL
GKIINGEMLWIIAISLSGISSIIGAVNFVTTIIRMRAPGMGFFKMPIFIWTVLAAQLLQLLGLPALTGGAIMLFFDLTFG
TSFFRVEGGGDPVLFQHFFWFYSHPAVYVMVLPVFGIFSELFPVYSRKPLFGYKFVAIASFGITILSLVVWVHHMFYTGT
PMWMRNLFMFTTMLIAVPTGVKVFAWIATLWGGNIRLSTPMLFCLGGLFNFIFGGITGVMLATVPVDIHVGNTYFVVAHF
HYIIFNTIAFGIFAAIYHWFPKFTGKMFYEGLGKIHFTLTFIGATLNWLPLHWAGLLGMPRRVASYDPEFAIWNVLASIG
AFILGVASIPFILNMVSSWVRGKSAPPNPWKAIGLEWLLPSPPPHENFEEDIPTVLNEPYCYGLDKPFVEDEKFYVEKSL
KKH
>Mature_562_residues
TIVNYDPRLVKTKNPYPKGPNDWKRFFSFNTDAKVIGIQYIVTALFFLLIGGLLGMLIRGELITPPSDLFDPTVYNGLYT
MHGTIMLFLFLFPILSGLTNLLVPPMIGAPDMAFPKLNALAFWLVPVFSIILLLSFFVPGGPASSGWWSYPPISIQNPLG
KIINGEMLWIIAISLSGISSIIGAVNFVTTIIRMRAPGMGFFKMPIFIWTVLAAQLLQLLGLPALTGGAIMLFFDLTFGT
SFFRVEGGGDPVLFQHFFWFYSHPAVYVMVLPVFGIFSELFPVYSRKPLFGYKFVAIASFGITILSLVVWVHHMFYTGTP
MWMRNLFMFTTMLIAVPTGVKVFAWIATLWGGNIRLSTPMLFCLGGLFNFIFGGITGVMLATVPVDIHVGNTYFVVAHFH
YIIFNTIAFGIFAAIYHWFPKFTGKMFYEGLGKIHFTLTFIGATLNWLPLHWAGLLGMPRRVASYDPEFAIWNVLASIGA
FILGVASIPFILNMVSSWVRGKSAPPNPWKAIGLEWLLPSPPPHENFEEDIPTVLNEPYCYGLDKPFVEDEKFYVEKSLK
KH

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=507, Percent_Identity=42.4063116370809, Blast_Score=366, Evalue=1e-101,
Organism=Escherichia coli, GI1786634, Length=513, Percent_Identity=38.2066276803119, Blast_Score=333, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6226519, Length=526, Percent_Identity=40.8745247148289, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6226524, Length=322, Percent_Identity=41.304347826087, Blast_Score=241, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6226523, Length=250, Percent_Identity=38.8, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 63104; Mature: 62973

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIVNYDPRLVKTKNPYPKGPNDWKRFFSFNTDAKVIGIQYIVTALFFLLIGGLLGMLIR
CEEECCCCCEEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GELITPPSDLFDPTVYNGLYTMHGTIMLFLFLFPILSGLTNLLVPPMIGAPDMAFPKLNA
CCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
LAFWLVPVFSIILLLSFFVPGGPASSGWWSYPPISIQNPLGKIINGEMLWIIAISLSGIS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEEEHHHHH
SIIGAVNFVTTIIRMRAPGMGFFKMPIFIWTVLAAQLLQLLGLPALTGGAIMLFFDLTFG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHC
TSFFRVEGGGDPVLFQHFFWFYSHPAVYVMVLPVFGIFSELFPVYSRKPLFGYKFVAIAS
CEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
FGITILSLVVWVHHMFYTGTPMWMRNLFMFTTMLIAVPTGVKVFAWIATLWGGNIRLSTP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCH
MLFCLGGLFNFIFGGITGVMLATVPVDIHVGNTYFVVAHFHYIIFNTIAFGIFAAIYHWF
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
PKFTGKMFYEGLGKIHFTLTFIGATLNWLPLHWAGLLGMPRRVASYDPEFAIWNVLASIG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHH
AFILGVASIPFILNMVSSWVRGKSAPPNPWKAIGLEWLLPSPPPHENFEEDIPTVLNEPY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEECCCCCCCCCCHHHHHHHHCCCC
CYGLDKPFVEDEKFYVEKSLKKH
EECCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TIVNYDPRLVKTKNPYPKGPNDWKRFFSFNTDAKVIGIQYIVTALFFLLIGGLLGMLIR
EEECCCCCEEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GELITPPSDLFDPTVYNGLYTMHGTIMLFLFLFPILSGLTNLLVPPMIGAPDMAFPKLNA
CCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
LAFWLVPVFSIILLLSFFVPGGPASSGWWSYPPISIQNPLGKIINGEMLWIIAISLSGIS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEEEHHHHH
SIIGAVNFVTTIIRMRAPGMGFFKMPIFIWTVLAAQLLQLLGLPALTGGAIMLFFDLTFG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHC
TSFFRVEGGGDPVLFQHFFWFYSHPAVYVMVLPVFGIFSELFPVYSRKPLFGYKFVAIAS
CEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
FGITILSLVVWVHHMFYTGTPMWMRNLFMFTTMLIAVPTGVKVFAWIATLWGGNIRLSTP
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCH
MLFCLGGLFNFIFGGITGVMLATVPVDIHVGNTYFVVAHFHYIIFNTIAFGIFAAIYHWF
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
PKFTGKMFYEGLGKIHFTLTFIGATLNWLPLHWAGLLGMPRRVASYDPEFAIWNVLASIG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHH
AFILGVASIPFILNMVSSWVRGKSAPPNPWKAIGLEWLLPSPPPHENFEEDIPTVLNEPY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEECCCCCCCCCCHHHHHHHHCCCC
CYGLDKPFVEDEKFYVEKSLKKH
EECCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]