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The map label for this gene is clpC [H]

Identifier: 123966412

GI number: 123966412

Start: 1034484

End: 1037015

Strand: Reverse

Name: clpC [H]

Synonym: P9515_11791

Alternate gene names: 123966412

Gene position: 1037015-1034484 (Counterclockwise)

Preceding gene: 123966413

Following gene: 123966411

Centisome position: 60.85

GC content: 36.3

Gene sequence:

>2532_bases
ATGTTCGAAAGATTTACAGAAAAAGCCATAAAAGTCATTATGCTTGCCCAAGAGGAAGCTAGAAGGCTTGGACATAATTT
TGTTGGAACAGAACAAATATTACTAGGCTTAATTGGTGAAGGTACTGGCGTTGCAGCTAAGGTGCTTAAATCACTAGGAG
TAAATCTTAAGGACTCAAGAATAGAAGTTGAAAAAATTATAGGAAGAGGTTCGGGTTTCGTTGCAGTTGAGATTCCTTTT
ACTCCAAGAGCAAAAAGAGTATTGGAGTTGTCTCTCGAAGAAGCTCGTCAATTAGGACATAACTATATAGGCACCGAACA
CCTACTTCTTGGTTTAATCAGGGAAGGCGAAGGTGTGGCTGCAAGAGTTTTAGAAAATCTAGGAATTGATCTGACAAAAG
TCAGAACCCAGGTTATAAGAATGCTTGGAGAGACCGCTGACGTTGGTACAGGTGGGACTTCATCAAATAAAGGAAATTTA
AAGACAGCAACTCTCGATGAATTCGGAACGAATTTAACAAAGCTTGCAAGTGAATCAAAACTTGATCCAGTTGTCGGACG
TTATGAGGAAATAGATAGAGTTATTCAAATCTTAGGTAGGAGAACTAAAAACAATCCTGTGCTTATTGGTGAACCAGGAG
TAGGTAAAACAGCTATAGCAGAAGGTTTAGCTCAAAGAATTCAACTTGGAGAAATTCCTGACATACTTGAAGATAAAAGG
GTTTTAACCCTTGATATAGGACTTCTTGTTGCAGGAACAAAATATAGAGGTGAATTTGAAGAGAGATTAAAAAAAATAAT
GGAAGAGATCAAATCAGCTGGAAACGTTATTCTGGTTATTGATGAAGTCCATACTTTAATCGGAGCCGGAGCTGCTGAAG
GTGCTATCGATGCCGCTAACATATTAAAGCCAGCTTTAGCTAGAGGAGAACTCCAATGCATAGGAGCTACAACTTTGGAT
GAATATAGAAAGCATATAGAAAGAGATGCAGCGCTGGAAAGAAGATTCCAACCGGTGATGGTGGGAGAGCCATCTATTGA
AGATACAATCGAAATTTTGAAAGGTTTAAGAGAACGTTACGAACAACATCATCGTTTAAAAATTACTGATGATGCTTTAG
AAGCAGCCGCTCATTTAGGTGATCGTTATATATCGGATAGATTTTTACCTGATAAGGCCATTGATCTTATAGATGAAGCA
GGAAGTAGAGTAAGATTAATAAATTCTAAGCTTCCTCCCGAAGCCAAACAAATTGATAAGGAATTAAGACAAGTTCAAAA
ACAAAAAGAAGAATCAGTAAGAGATCAAAATTTTGATCAAGCAGGTCAGTTAAGGGAAAAGGAAATTGAATTGTCTGAAA
AAATTAAAGAGCTTTTAGATAGTAAAAAAGAGAGCTTAGATAAAAATAATTCAAGTAATGCTTCGGAAACTGAAGACGGT
GGCATTGATATTACTCAAAACCCTCTTGTAAGTGAAGAAGATGTGGCTCATATAGTGGCTTCATGGACAGGTGTTCCTGT
TCAGAAATTAACAGAAACCGAGTCAGTCAAACTCCTTAATATGGAAGAGACATTGCATCAAAGACTTATAGGCCAAGATG
AGGCTGTAAAAGCAGTATCAAAAGCCATTAGAAGAGCTAGGGTCGGTTTGAAAAATCCTAATAGACCAATCGCAAGCTTT
ATTTTTTCAGGCCCTACTGGTGTTGGGAAAACTGAATTAACTAAATCATTAGCATCATATTTCTTTGGTAGTGAGGAAGC
TATGATTAGATTAGATATGTCTGAATTTATGGAAAGACATACTGTTAGTAAGTTAATCGGTTCCCCTCCCGGATATGTTG
GTTTCAACGAAGGGGGTCAACTTACAGAGGCTGTAAGAAGAAGACCATACACTGTAGTTTTATTCGATGAAGTGGAGAAA
GCTCATCCAGATGTTTTTAATTTGTTATTACAACTTCTTGAAGATGGTAGATTAACAGACTCAAAGGGTAGAACAGTTGA
TTTTAAAAATACGCTTTTAATAATGACTTCTAATATTGGCTCTAAAGTTATCGAGAAAGGTGGCGGTGGTTTAGGTTTTG
AATTTTCCGGCGATTCCGTTGAAGATAGCCAATACAATAGGATCAAATCTCTTGTAAACGAGGAACTAAAACAATACTTT
AGACCTGAGTTTTTAAACAGACTTGACGAGATAATTGTATTCAGACAATTAACTAAAAACGAAGTTAAAGACATCGCAGA
AATAATGTTAAAAGAAGTATTCTCTCGATTAAATGAAAAGGGTATAAAATTAGATGTTACTGAAGCATTTAAAGAAAGAC
TTGTTGAAGAGGGATATAATCCAGCCTATGGAGCAAGACCTTTAAGAAGAGCAGTCATGCGCTTATTAGAAGATAGTTTG
GCTGAAGAAGTTTTATCAGGAAGAATTAAAGATGGAGACAAAGCTTTAGTCGATATTGATGAAAATAAGAAAGTTACAGT
AAATATTTCCTCAGAAGAATCTTCTCAAGAATTAGCAGGAGCTAATTTTTAA

Upstream 100 bases:

>100_bases
ATTTTACTAAATGAAACTTTTGGGTATTCACAAAAGCTCATTCTGAACACAAAATCGACTTAATACTGGTAGGTTATTAG
TAAGGAACTAAAACCCTCTA

Downstream 100 bases:

>100_bases
TAATCTAGGTGCATATGCAGTCAATATCACCAGAAAAAATATTTAGGGGGAGTGGAGCTTGGATAAAAGCTATACCACAT
ATTAAAAGTATTTCAAAACG

Product: ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 843; Mature: 843

Protein sequence:

>843_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSRIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGIDLTKVRTQVIRMLGETADVGTGGTSSNKGNL
KTATLDEFGTNLTKLASESKLDPVVGRYEEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQLGEIPDILEDKR
VLTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLD
EYRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYEQHHRLKITDDALEAAAHLGDRYISDRFLPDKAIDLIDEA
GSRVRLINSKLPPEAKQIDKELRQVQKQKEESVRDQNFDQAGQLREKEIELSEKIKELLDSKKESLDKNNSSNASETEDG
GIDITQNPLVSEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSKAIRRARVGLKNPNRPIASF
IFSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEK
AHPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYF
RPEFLNRLDEIIVFRQLTKNEVKDIAEIMLKEVFSRLNEKGIKLDVTEAFKERLVEEGYNPAYGARPLRRAVMRLLEDSL
AEEVLSGRIKDGDKALVDIDENKKVTVNISSEESSQELAGANF

Sequences:

>Translated_843_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSRIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGIDLTKVRTQVIRMLGETADVGTGGTSSNKGNL
KTATLDEFGTNLTKLASESKLDPVVGRYEEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQLGEIPDILEDKR
VLTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLD
EYRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYEQHHRLKITDDALEAAAHLGDRYISDRFLPDKAIDLIDEA
GSRVRLINSKLPPEAKQIDKELRQVQKQKEESVRDQNFDQAGQLREKEIELSEKIKELLDSKKESLDKNNSSNASETEDG
GIDITQNPLVSEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSKAIRRARVGLKNPNRPIASF
IFSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEK
AHPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYF
RPEFLNRLDEIIVFRQLTKNEVKDIAEIMLKEVFSRLNEKGIKLDVTEAFKERLVEEGYNPAYGARPLRRAVMRLLEDSL
AEEVLSGRIKDGDKALVDIDENKKVTVNISSEESSQELAGANF
>Mature_843_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSRIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGIDLTKVRTQVIRMLGETADVGTGGTSSNKGNL
KTATLDEFGTNLTKLASESKLDPVVGRYEEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQLGEIPDILEDKR
VLTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLD
EYRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYEQHHRLKITDDALEAAAHLGDRYISDRFLPDKAIDLIDEA
GSRVRLINSKLPPEAKQIDKELRQVQKQKEESVRDQNFDQAGQLREKEIELSEKIKELLDSKKESLDKNNSSNASETEDG
GIDITQNPLVSEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSKAIRRARVGLKNPNRPIASF
IFSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEK
AHPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYF
RPEFLNRLDEIIVFRQLTKNEVKDIAEIMLKEVFSRLNEKGIKLDVTEAFKERLVEEGYNPAYGARPLRRAVMRLLEDSL
AEEVLSGRIKDGDKALVDIDENKKVTVNISSEESSQELAGANF

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=329, Percent_Identity=38.6018237082067, Blast_Score=203, Evalue=7e-52,
Organism=Escherichia coli, GI1788943, Length=883, Percent_Identity=46.9988674971687, Blast_Score=749, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=823, Percent_Identity=36.5735115431349, Blast_Score=493, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6320464, Length=710, Percent_Identity=48.4507042253521, Blast_Score=640, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=894, Percent_Identity=36.4653243847875, Blast_Score=543, Evalue=1e-155,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 93556; Mature: 93556

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50151 UVR ; PS00036 BZIP_BASIC ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
IEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGIDLTKVRTQVIRMLGETADVGTGGTSSNKGNLKTATLDEFGTNLTKLASESK
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHCCHHHHHHHHCC
LDPVVGRYEEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQLGEIPDILEDKR
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCE
VLTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAAN
EEEEEEEEHEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCHHHH
ILKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERY
HHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHH
EQHHRLKITDDALEAAAHLGDRYISDRFLPDKAIDLIDEAGSRVRLINSKLPPEAKQIDK
HHHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
ELRQVQKQKEESVRDQNFDQAGQLREKEIELSEKIKELLDSKKESLDKNNSSNASETEDG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GIDITQNPLVSEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVS
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCEEEECHHHHHHHHHCCCHHHHHHHH
KAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERH
HHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHH
TVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKAHPDVFNLLLQLLEDGRLTD
HHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHHCCCCCC
SKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYF
CCCCEEEECCEEEEEECCCCHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHH
RPEFLNRLDEIIVFRQLTKNEVKDIAEIMLKEVFSRLNEKGIKLDVTEAFKERLVEEGYN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCC
PAYGARPLRRAVMRLLEDSLAEEVLSGRIKDGDKALVDIDENKKVTVNISSEESSQELAG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEECCCCCHHHHCC
ANF
CCC
>Mature Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
IEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGIDLTKVRTQVIRMLGETADVGTGGTSSNKGNLKTATLDEFGTNLTKLASESK
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHCCHHHHHHHHCC
LDPVVGRYEEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQLGEIPDILEDKR
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCE
VLTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAAN
EEEEEEEEHEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCHHHH
ILKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERY
HHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHH
EQHHRLKITDDALEAAAHLGDRYISDRFLPDKAIDLIDEAGSRVRLINSKLPPEAKQIDK
HHHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
ELRQVQKQKEESVRDQNFDQAGQLREKEIELSEKIKELLDSKKESLDKNNSSNASETEDG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GIDITQNPLVSEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVS
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCEEEECHHHHHHHHHCCCHHHHHHHH
KAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERH
HHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHH
TVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKAHPDVFNLLLQLLEDGRLTD
HHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHHCCCCCC
SKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYF
CCCCEEEECCEEEEEECCCCHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHH
RPEFLNRLDEIIVFRQLTKNEVKDIAEIMLKEVFSRLNEKGIKLDVTEAFKERLVEEGYN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCC
PAYGARPLRRAVMRLLEDSLAEEVLSGRIKDGDKALVDIDENKKVTVNISSEESSQELAG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEECCCCCHHHHCC
ANF
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]