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The map label for this gene is pkwA [H]

Identifier: 123966361

GI number: 123966361

Start: 983771

End: 984844

Strand: Direct

Name: pkwA [H]

Synonym: P9515_11281

Alternate gene names: 123966361

Gene position: 983771-984844 (Clockwise)

Preceding gene: 123966360

Following gene: 123966363

Centisome position: 57.73

GC content: 40.88

Gene sequence:

>1074_bases
GTGCCTGATATAGAACCGTTTAACCCTAGAGGGATGTTTCATGAGGGCTGGTCTGCTGAAGTTGAAGATTATGCAATAGT
TTGTGGTTGGGCTTTAGGAGGAAAACTTTTTATTGTCGGAGATGTAGCCGGAGGAGTTTACGGGTTCGAGGGGGATACAG
GTAAAATTGTTTGGGAAAAGAATGAAGCCCATTCAGGAGGTCTTCTTGCAATGTCTATTCATCCAAATGGAAATATTTTT
GCGACTTCAGGACAAGATGGAATAGTTCGAATATGTAATTGTAATAATGGTGAGAAAATTAAGGACATTAAACTTGGCAA
ATGTTGGGTAGAGCATCTAAGTTGGTCAAATGATGGCTCATTTTTAGCTGCAGCCTTTTCCAAAAAAGTGTATGTACTTA
ATCAGGAGGGTAATGAAAATTGGGTTTCAGAGGAACATCCAAGCACAGTAAGTGCAATATCATGGTCAAATAAAAATGAA
TTAGCAACTGCCTGTTATGGTCAAGTAACTTTCTTTGATGTAGCTAATAATAAAACCAATCAAAAACTTAAATGGCAAGG
ATCCTTGGTGTCGATGAAGTTAAGCCCCGATGGAGATATTGTTGCATGCGGAAGTCAAGATAATTCTGTACACTTCTGGC
GAAGATCAACTGGACAAGATGCTGAAATGACCGGTTATCCAGCAAAGCCTTCTCACCTCTCTTTTGATGAAACAGGCATG
CTATTAGCAACTAGTGGAAGCGAAAGAATTACTGTATGGAGTTTTTCAGGGAATGGCCCTCAAGGTACGATCCCGGGAGA
ATTATGTCATCATACAGAACCAGTTTCTAGCCTAGCTTTTTCTAACAAAGGTTTGCTAGTTGCTTCAGGATCAAGAGATG
GTTCAGTCGTAGCTAGTTTTCTTAAAAAAGACGGGAATGGGGATCCTGTTGGAGCTGCTTTTGCCGGTGATTTAGTTGGA
GATATTGCGTGGAGACCCGATGACTGCGCTTTAGCCGCAGTTAATGCAAAGGGTGTTGTAACAGTTTGGAATTTCAAAGT
CCGTACGACTTCCATTTCAAAGGGGTTCAAGTAA

Upstream 100 bases:

>100_bases
CTCAGCCAGATAAAGAATGGGGTAATGAACCTCGTAGAAATCAACTTGTATTTATTGGCAGAAATCTTAATGAAAAAGAG
ATGCAGGAGGGATTTGATAA

Downstream 100 bases:

>100_bases
TTACAAGCTAATAGCTTTACCAATAATTAGCTTTTAAATGTCTCTCCATACAAATCACTTCGCAATCATTATCAATACCT
TTTGGATGAATATCGCAATA

Product: WD-40 repeat-containing G-protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MPDIEPFNPRGMFHEGWSAEVEDYAIVCGWALGGKLFIVGDVAGGVYGFEGDTGKIVWEKNEAHSGGLLAMSIHPNGNIF
ATSGQDGIVRICNCNNGEKIKDIKLGKCWVEHLSWSNDGSFLAAAFSKKVYVLNQEGNENWVSEEHPSTVSAISWSNKNE
LATACYGQVTFFDVANNKTNQKLKWQGSLVSMKLSPDGDIVACGSQDNSVHFWRRSTGQDAEMTGYPAKPSHLSFDETGM
LLATSGSERITVWSFSGNGPQGTIPGELCHHTEPVSSLAFSNKGLLVASGSRDGSVVASFLKKDGNGDPVGAAFAGDLVG
DIAWRPDDCALAAVNAKGVVTVWNFKVRTTSISKGFK

Sequences:

>Translated_357_residues
MPDIEPFNPRGMFHEGWSAEVEDYAIVCGWALGGKLFIVGDVAGGVYGFEGDTGKIVWEKNEAHSGGLLAMSIHPNGNIF
ATSGQDGIVRICNCNNGEKIKDIKLGKCWVEHLSWSNDGSFLAAAFSKKVYVLNQEGNENWVSEEHPSTVSAISWSNKNE
LATACYGQVTFFDVANNKTNQKLKWQGSLVSMKLSPDGDIVACGSQDNSVHFWRRSTGQDAEMTGYPAKPSHLSFDETGM
LLATSGSERITVWSFSGNGPQGTIPGELCHHTEPVSSLAFSNKGLLVASGSRDGSVVASFLKKDGNGDPVGAAFAGDLVG
DIAWRPDDCALAAVNAKGVVTVWNFKVRTTSISKGFK
>Mature_356_residues
PDIEPFNPRGMFHEGWSAEVEDYAIVCGWALGGKLFIVGDVAGGVYGFEGDTGKIVWEKNEAHSGGLLAMSIHPNGNIFA
TSGQDGIVRICNCNNGEKIKDIKLGKCWVEHLSWSNDGSFLAAAFSKKVYVLNQEGNENWVSEEHPSTVSAISWSNKNEL
ATACYGQVTFFDVANNKTNQKLKWQGSLVSMKLSPDGDIVACGSQDNSVHFWRRSTGQDAEMTGYPAKPSHLSFDETGML
LATSGSERITVWSFSGNGPQGTIPGELCHHTEPVSSLAFSNKGLLVASGSRDGSVVASFLKKDGNGDPVGAAFAGDLVGD
IAWRPDDCALAAVNAKGVVTVWNFKVRTTSISKGFK

Specific function: May play a regulatory role during the complex growth cycle and in secondary metabolite production [H]

COG id: COG2319

COG function: function code R; FOG: WD40 repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 7 WD repeats [H]

Homologues:

Organism=Homo sapiens, GI113865883, Length=269, Percent_Identity=24.5353159851301, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020472
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271
- InterPro:   IPR015943
- InterPro:   IPR001680
- InterPro:   IPR011046
- InterPro:   IPR019782
- InterPro:   IPR019775
- InterPro:   IPR017986
- InterPro:   IPR019781 [H]

Pfam domain/function: PF00069 Pkinase; PF00400 WD40 [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 38250; Mature: 38119

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50082 WD_REPEATS_2 ; PS50294 WD_REPEATS_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDIEPFNPRGMFHEGWSAEVEDYAIVCGWALGGKLFIVGDVAGGVYGFEGDTGKIVWEK
CCCCCCCCCCCCEECCCCCCCCCEEEEEEEECCCEEEEEEECCCCEEEEECCCCEEEEEC
NEAHSGGLLAMSIHPNGNIFATSGQDGIVRICNCNNGEKIKDIKLGKCWVEHLSWSNDGS
CCCCCCCEEEEEECCCCCEEEECCCCCEEEEEECCCCCEEEEEEHHHHHHHHCCCCCCCC
FLAAAFSKKVYVLNQEGNENWVSEEHPSTVSAISWSNKNELATACYGQVTFFDVANNKTN
EEEEEECCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECEEEEEEECCCCCC
QKLKWQGSLVSMKLSPDGDIVACGSQDNSVHFWRRSTGQDAEMTGYPAKPSHLSFDETGM
CEEEEECEEEEEEECCCCCEEEECCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCE
LLATSGSERITVWSFSGNGPQGTIPGELCHHTEPVSSLAFSNKGLLVASGSRDGSVVASF
EEEECCCCEEEEEEECCCCCCCCCCHHHHCCCCCHHHHHCCCCCEEEEECCCCHHHHHHH
LKKDGNGDPVGAAFAGDLVGDIAWRPDDCALAAVNAKGVVTVWNFKVRTTSISKGFK
HHCCCCCCCCCCEEHHHHHHCCCCCCCCCEEEEECCCCEEEEEEEEEEEECCCCCCC
>Mature Secondary Structure 
PDIEPFNPRGMFHEGWSAEVEDYAIVCGWALGGKLFIVGDVAGGVYGFEGDTGKIVWEK
CCCCCCCCCCCEECCCCCCCCCEEEEEEEECCCEEEEEEECCCCEEEEECCCCEEEEEC
NEAHSGGLLAMSIHPNGNIFATSGQDGIVRICNCNNGEKIKDIKLGKCWVEHLSWSNDGS
CCCCCCCEEEEEECCCCCEEEECCCCCEEEEEECCCCCEEEEEEHHHHHHHHCCCCCCCC
FLAAAFSKKVYVLNQEGNENWVSEEHPSTVSAISWSNKNELATACYGQVTFFDVANNKTN
EEEEEECCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECEEEEEEECCCCCC
QKLKWQGSLVSMKLSPDGDIVACGSQDNSVHFWRRSTGQDAEMTGYPAKPSHLSFDETGM
CEEEEECEEEEEEECCCCCEEEECCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCE
LLATSGSERITVWSFSGNGPQGTIPGELCHHTEPVSSLAFSNKGLLVASGSRDGSVVASF
EEEECCCCEEEEEEECCCCCCCCCCHHHHCCCCCHHHHHCCCCCEEEEECCCCHHHHHHH
LKKDGNGDPVGAAFAGDLVGDIAWRPDDCALAAVNAKGVVTVWNFKVRTTSISKGFK
HHCCCCCCCCCCEEHHHHHHCCCCCCCCCEEEEECCCCEEEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631732 [H]