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The map label for this gene is ubiE [C]

Identifier: 123966237

GI number: 123966237

Start: 899150

End: 900205

Strand: Direct

Name: ubiE [C]

Synonym: P9515_10041

Alternate gene names: 123966237

Gene position: 899150-900205 (Clockwise)

Preceding gene: 123966236

Following gene: 123966238

Centisome position: 52.76

GC content: 30.21

Gene sequence:

>1056_bases
ATGTCAAGAGAACCAATTTCAAAAATCGCTTATAAAACACTTCAACAGGGAAAAAGTATTGCTGGACTAGCTCATAAGGA
ATTAAGTACAAGGATCATGAATTTTATTCTTCCTGACAATAAATTTGGCAATTTAGATATAGATAAAAAGCTCTTGGTTG
ATATTCAAAATTCAATGGATCGTCTCAGAGAAGAGGATTGGGATGATGCTGAAAAAAATATTTATCCTCAAAAATTACTA
TTTGATGAACCTTGGCTAAGATATTTGACCCAATATCCAAAAATTTGGTTAGATATGCCAAACACATGGGACAGAAGAAG
AAAACAAAATTATAATGATCTTCCTAAAAATATTGATAATGAGAACTACCCAAAATATTATTTAAGAAACTTTCATCATC
AGACAGACGGATATTTATCAGATTTTTCAGCAAGTATTTATGATTTGCAAGTAGAAATTCTTTTTAACGGAAGTGCCGAT
GCTATGAGGAGAAGAATAATTAAACCACTTAAGGAAGGTTTAAATAATTTTAGCAGTCGAAAAAAAAGTTCTTTAAACAT
ACTAGATGTTGCTACAGGTTCCGGTAGAACACTTAAACAGTTGAGAGGGGCATTTCCTAAAGAAAAGATAATGGGATTAG
ATTTGTCTGGATCCTACTTAAAGGAAGCCAGCAGATTTATTTCAAATTTAGATGGTGATTTAATTGAATTAATTAAAGGT
AACGCTGAAGAATTACCATTCGAAGAAAATACCCTCCAAGGAATTACATGTGTTTATTTATTTCATGAATTACCTAGAAC
TGTAAGAGAGAATGTCTTAAAAGAATTTTTTAGAGTACTTGAACCGGGTGGCAGTTTAATACTGGCTGATTCGATACAAG
TAAGTGATTCTCCTGATTTTATAAAGATAATGGAAAATTTCTATAAATCATTTCATGAACCATTTTATTGTGATTACATC
AAAGAAGACATAACTACTAAAATAAAAGAAATTGGTTTTAACAATGTAAAATCAAATTCTTTTTTCATGACTAAAGTATG
GTCTGCTATAAAATAG

Upstream 100 bases:

>100_bases
AAACATTTAAGCATTTTTTAAAATGTCATTTTGAGAATTATCACAAATAATTCTCAAATTGATTTTTTTTTTGTTGAAAT
ATAGTTAAGTAGTAAAAAAA

Downstream 100 bases:

>100_bases
AGAGATAATATAAAATTGCCATGAATAACTGGGACGAAGATATTATAGAACTTGCACAAAAATTGAATTCTAAACTAAAA
ATTAATCATATTGATTGGCA

Product: methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; Methyltransferase Domain Family; UbiE/COQ5 Family Methlytransferase; Methyltransferase UbiE/COQ5 Family Protein; SAM-Dependent Methyltransferase; Methyltransferase UbiE; Generic Methyl-Transferase; UbiE/COQ5 Methyltransferase; Methyltransferase UbiE/COQ5 Family; Methlytransferase; Ubiquinone/Menaquinone Biosynthesis Protein

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSREPISKIAYKTLQQGKSIAGLAHKELSTRIMNFILPDNKFGNLDIDKKLLVDIQNSMDRLREEDWDDAEKNIYPQKLL
FDEPWLRYLTQYPKIWLDMPNTWDRRRKQNYNDLPKNIDNENYPKYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSAD
AMRRRIIKPLKEGLNNFSSRKKSSLNILDVATGSGRTLKQLRGAFPKEKIMGLDLSGSYLKEASRFISNLDGDLIELIKG
NAEELPFEENTLQGITCVYLFHELPRTVRENVLKEFFRVLEPGGSLILADSIQVSDSPDFIKIMENFYKSFHEPFYCDYI
KEDITTKIKEIGFNNVKSNSFFMTKVWSAIK

Sequences:

>Translated_351_residues
MSREPISKIAYKTLQQGKSIAGLAHKELSTRIMNFILPDNKFGNLDIDKKLLVDIQNSMDRLREEDWDDAEKNIYPQKLL
FDEPWLRYLTQYPKIWLDMPNTWDRRRKQNYNDLPKNIDNENYPKYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSAD
AMRRRIIKPLKEGLNNFSSRKKSSLNILDVATGSGRTLKQLRGAFPKEKIMGLDLSGSYLKEASRFISNLDGDLIELIKG
NAEELPFEENTLQGITCVYLFHELPRTVRENVLKEFFRVLEPGGSLILADSIQVSDSPDFIKIMENFYKSFHEPFYCDYI
KEDITTKIKEIGFNNVKSNSFFMTKVWSAIK
>Mature_350_residues
SREPISKIAYKTLQQGKSIAGLAHKELSTRIMNFILPDNKFGNLDIDKKLLVDIQNSMDRLREEDWDDAEKNIYPQKLLF
DEPWLRYLTQYPKIWLDMPNTWDRRRKQNYNDLPKNIDNENYPKYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSADA
MRRRIIKPLKEGLNNFSSRKKSSLNILDVATGSGRTLKQLRGAFPKEKIMGLDLSGSYLKEASRFISNLDGDLIELIKGN
AEELPFEENTLQGITCVYLFHELPRTVRENVLKEFFRVLEPGGSLILADSIQVSDSPDFIKIMENFYKSFHEPFYCDYIK
EDITTKIKEIGFNNVKSNSFFMTKVWSAIK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 40964; Mature: 40833

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSREPISKIAYKTLQQGKSIAGLAHKELSTRIMNFILPDNKFGNLDIDKKLLVDIQNSMD
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
RLREEDWDDAEKNIYPQKLLFDEPWLRYLTQYPKIWLDMPNTWDRRRKQNYNDLPKNIDN
HHHHCCCCCHHHCCCCHHHHCCCHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCC
ENYPKYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSADAMRRRIIKPLKEGLNNFSSR
CCCCHHHHHHHCCCCCCHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
KKSSLNILDVATGSGRTLKQLRGAFPKEKIMGLDLSGSYLKEASRFISNLDGDLIELIKG
HHCCCCEEEECCCCCHHHHHHHCCCCHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHCC
NAEELPFEENTLQGITCVYLFHELPRTVRENVLKEFFRVLEPGGSLILADSIQVSDSPDF
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEECCCCCHH
IKIMENFYKSFHEPFYCDYIKEDITTKIKEIGFNNVKSNSFFMTKVWSAIK
HHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SREPISKIAYKTLQQGKSIAGLAHKELSTRIMNFILPDNKFGNLDIDKKLLVDIQNSMD
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
RLREEDWDDAEKNIYPQKLLFDEPWLRYLTQYPKIWLDMPNTWDRRRKQNYNDLPKNIDN
HHHHCCCCCHHHCCCCHHHHCCCHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCC
ENYPKYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSADAMRRRIIKPLKEGLNNFSSR
CCCCHHHHHHHCCCCCCHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
KKSSLNILDVATGSGRTLKQLRGAFPKEKIMGLDLSGSYLKEASRFISNLDGDLIELIKG
HHCCCCEEEECCCCCHHHHHHHCCCCHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHCC
NAEELPFEENTLQGITCVYLFHELPRTVRENVLKEFFRVLEPGGSLILADSIQVSDSPDF
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEECCCCCHH
IKIMENFYKSFHEPFYCDYIKEDITTKIKEIGFNNVKSNSFFMTKVWSAIK
HHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA