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The map label for this gene is trpS [H]

Identifier: 123965898

GI number: 123965898

Start: 599203

End: 600246

Strand: Reverse

Name: trpS [H]

Synonym: P9515_06631

Alternate gene names: 123965898

Gene position: 600246-599203 (Counterclockwise)

Preceding gene: 123965899

Following gene: 123965897

Centisome position: 35.22

GC content: 31.9

Gene sequence:

>1044_bases
ATGGAGAAGGAGAAGAAGAAGAAGGGGATGACAAATAAAAAAAGAGTTCTTTCTGGAGTTCAACCTACAGGAGATTTACA
CATTGGAAACTGGCTTGGAGCAATAAACAATTGGGTTGCACTTCAAGAGAAGCACGAAACATTTCTTTGTGTGGTTGATT
TGCACGCAATTACTACAGAATATGACCCAAAACAGCTTTCAAGGAATACACTTTCAACAGCTGCTTTATATGTTGCTTGT
GGTATAGATCCAAAAATATGTTCTATTTTTGTTCAAAGCCAGATATCTGCTCATTCAGAGCTTTGCTGGATATTAAATTG
CATGACTCCCATAAATTGGATGGAAAGGATGATCCAATTCAAGGAGAAATCTGTCCAGCAAGGAAATAATGTTTCTATTG
GATTATTTGATTATCCAATATTAATGGCTGCTGATATTTTGCTATACGATGCTGATTATGTTCCCGTAGGAGAAGATCAA
AAACAACATTTAGAACTTGCTAGAGATATTGCCCAACAGAGAATAAATGCCAAGTTTAGTAAGAAAAAAAATATTTTAAA
AATTCCTCAACCAATAATTATGAAGAAAGGTTCAAAGATAATGAGTCTAAATGATGGATCAAAAAAAATGAGCAAAAGCG
ATATTAACGAGGGTAGTAGAATTAATCTATTAGATACTCCAGAAATTATTACAAAAAAAATAAAAAGAGCTAAAAGTGAT
AGTCATATCGGAATGGAATTTAATAATCCCGATAGGCCTGAATCCAGAAATCTTTTAATGATATATTCATTATTAAGTGG
TAAAGAAATTTCTGATTTAGAGAATGATTTCTCGCAAACAGGATGGGGAACTTTTAAAAAAATATTTACTGAACAAGTTA
TAGAATCGCTTGAACCTATTCAAGAAAGATATAATGTTCTTATTAATGATCCATATGAACTAAATAAGATACTTCTAGAG
GGTAAAGAGAAAGCTGAGTTAGTAGCAAACAAAACTCTAAGTAGAGTTAAATCAGAATTAGGTTTCTTTTCAATGGAAAA
ATAA

Upstream 100 bases:

>100_bases
GAGAGCGAAAGTATAAAAGCAGCGCCTAATCCTTTTGCAAGGCCAGTTAAGAATCAGCCTATTGAAAAAATTACACCAAA
AACAGAGGAGCTCAAAGGAG

Downstream 100 bases:

>100_bases
ATCATGCCAAAAATAACACTCCCTGATGGTACTAAAAAAGTTTTCGAAAAAGCTGTAACTACTCTTGATATTGCTAAAAG
TATTGGAGCAGGGTTAGCCA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MEKEKKKKGMTNKKRVLSGVQPTGDLHIGNWLGAINNWVALQEKHETFLCVVDLHAITTEYDPKQLSRNTLSTAALYVAC
GIDPKICSIFVQSQISAHSELCWILNCMTPINWMERMIQFKEKSVQQGNNVSIGLFDYPILMAADILLYDADYVPVGEDQ
KQHLELARDIAQQRINAKFSKKKNILKIPQPIIMKKGSKIMSLNDGSKKMSKSDINEGSRINLLDTPEIITKKIKRAKSD
SHIGMEFNNPDRPESRNLLMIYSLLSGKEISDLENDFSQTGWGTFKKIFTEQVIESLEPIQERYNVLINDPYELNKILLE
GKEKAELVANKTLSRVKSELGFFSMEK

Sequences:

>Translated_347_residues
MEKEKKKKGMTNKKRVLSGVQPTGDLHIGNWLGAINNWVALQEKHETFLCVVDLHAITTEYDPKQLSRNTLSTAALYVAC
GIDPKICSIFVQSQISAHSELCWILNCMTPINWMERMIQFKEKSVQQGNNVSIGLFDYPILMAADILLYDADYVPVGEDQ
KQHLELARDIAQQRINAKFSKKKNILKIPQPIIMKKGSKIMSLNDGSKKMSKSDINEGSRINLLDTPEIITKKIKRAKSD
SHIGMEFNNPDRPESRNLLMIYSLLSGKEISDLENDFSQTGWGTFKKIFTEQVIESLEPIQERYNVLINDPYELNKILLE
GKEKAELVANKTLSRVKSELGFFSMEK
>Mature_347_residues
MEKEKKKKGMTNKKRVLSGVQPTGDLHIGNWLGAINNWVALQEKHETFLCVVDLHAITTEYDPKQLSRNTLSTAALYVAC
GIDPKICSIFVQSQISAHSELCWILNCMTPINWMERMIQFKEKSVQQGNNVSIGLFDYPILMAADILLYDADYVPVGEDQ
KQHLELARDIAQQRINAKFSKKKNILKIPQPIIMKKGSKIMSLNDGSKKMSKSDINEGSRINLLDTPEIITKKIKRAKSD
SHIGMEFNNPDRPESRNLLMIYSLLSGKEISDLENDFSQTGWGTFKKIFTEQVIESLEPIQERYNVLINDPYELNKILLE
GKEKAELVANKTLSRVKSELGFFSMEK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=333, Percent_Identity=37.5375375375375, Blast_Score=238, Evalue=6e-63,
Organism=Homo sapiens, GI41352700, Length=184, Percent_Identity=46.7391304347826, Blast_Score=179, Evalue=2e-45,
Organism=Escherichia coli, GI1789786, Length=335, Percent_Identity=45.9701492537313, Blast_Score=300, Evalue=8e-83,
Organism=Caenorhabditis elegans, GI71982800, Length=335, Percent_Identity=34.9253731343284, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71982793, Length=341, Percent_Identity=34.6041055718475, Blast_Score=183, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6320474, Length=350, Percent_Identity=39.1428571428571, Blast_Score=209, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24666151, Length=333, Percent_Identity=39.6396396396396, Blast_Score=245, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 39498; Mature: 39498

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKEKKKKGMTNKKRVLSGVQPTGDLHIGNWLGAINNWVALQEKHETFLCVVDLHAITTE
CCCHHHHCCCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHEEECCCEEEEEEEEHHHHCC
YDPKQLSRNTLSTAALYVACGIDPKICSIFVQSQISAHSELCWILNCMTPINWMERMIQF
CCHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
KEKSVQQGNNVSIGLFDYPILMAADILLYDADYVPVGEDQKQHLELARDIAQQRINAKFS
HHHHHHCCCCEEEEEECCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHH
KKKNILKIPQPIIMKKGSKIMSLNDGSKKMSKSDINEGSRINLLDTPEIITKKIKRAKSD
HCCCCEECCCHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCC
SHIGMEFNNPDRPESRNLLMIYSLLSGKEISDLENDFSQTGWGTFKKIFTEQVIESLEPI
CCCCEECCCCCCCCCCCEEEEEEHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
QERYNVLINDPYELNKILLEGKEKAELVANKTLSRVKSELGFFSMEK
HHHCCEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEKEKKKKGMTNKKRVLSGVQPTGDLHIGNWLGAINNWVALQEKHETFLCVVDLHAITTE
CCCHHHHCCCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHEEECCCEEEEEEEEHHHHCC
YDPKQLSRNTLSTAALYVACGIDPKICSIFVQSQISAHSELCWILNCMTPINWMERMIQF
CCHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
KEKSVQQGNNVSIGLFDYPILMAADILLYDADYVPVGEDQKQHLELARDIAQQRINAKFS
HHHHHHCCCCEEEEEECCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHH
KKKNILKIPQPIIMKKGSKIMSLNDGSKKMSKSDINEGSRINLLDTPEIITKKIKRAKSD
HCCCCEECCCHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCC
SHIGMEFNNPDRPESRNLLMIYSLLSGKEISDLENDFSQTGWGTFKKIFTEQVIESLEPI
CCCCEECCCCCCCCCCCEEEEEEHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
QERYNVLINDPYELNKILLEGKEKAELVANKTLSRVKSELGFFSMEK
HHHCCEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]