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The map label for this gene is clpB [H]

Identifier: 123965880

GI number: 123965880

Start: 574894

End: 577425

Strand: Reverse

Name: clpB [H]

Synonym: P9515_06451

Alternate gene names: 123965880

Gene position: 577425-574894 (Counterclockwise)

Preceding gene: 123965881

Following gene: 123965878

Centisome position: 33.88

GC content: 29.23

Gene sequence:

>2532_bases
TTGTCGAAAAAAATAGCAGCTAATAATTTTCAGCAAACTGTAGATTCAGAAAATTTATTACTTACAATAATAAAAGAAGA
CAGTCTTGCAAAAGAAATACTTAAGAAAAACGAAGTAGATATTGAAAAGATAGAAAAAGATTTAATTTCTTTATTAAATT
CAAAAGCAAAGATGAAGAACAAGCAAAAAATATTGTACATAGGAGAAAGCCTCAATAACATTTTTTTAAAATCAAATGAT
TTAAGAGTTTCCTTAAACGATGTAGTGATATCAACAGAACACTTGCTTTACGGTTTGTCTTATGATGAAGTGTGCGGAAA
GTTAATTTTAAATAAGAAAAAAATTCCAGACTTTTTAGAAACCATAATTGAAATGAAATCCAATCCGAAAATTCAAAATA
ATTTTGAAAGTCCTAATGAATCTTTAGACAAATTCGGTATTGATTTAACTAAATCAGCTTCAGAGGGTAACTTAGACCCA
GTTATTGGAAGGGATGAAGAAATCAGAAGAACTATACAAATACTAAGCAGAAGAACAAAAAACAATCCTGTTCTAATAGG
AGAGCCCGGGGTAGGCAAAACAGCAATAGTTGAAGGGTTAGCTCAAAGAATAGTTAATGGAGATGTCCCATCTTCCTTAC
ATAATAGGCGTTTAATCTCATTAGATATGGGTTCATTAATAGCCGGAGCTAAGTACAGAGGAGAATTTGAAGAGAGAATT
AAAAATGTTTTAAAAAAAGTTAAAAGTTCTGCAGGTAAAATTATTCTTTTTATTGATGAAATACATACAGTTGTTGGAGC
AGGTGCGAGCGGAGGTTCTTTAGATGCAAGTAACCTTTTAAAGCCTATGCTCGCGAGAGGGGAATTAAGATGTATTGGTG
CTACTACAATTAATGAACACAAACAAAATATAGAAAAAGATCCCGCTTTAGAAAGAAGATTTCAAAAAATTAAAATAAAC
GCGCCTTCAGTAGATGATACTGTTTCAATACTTAGAGGACTTAAAGAAAAATATGAAGTTCACCATAGTGTAAGAATTTC
TGACAATGCTCTTGTTGCCGCTGCCAGCTTAAGCGAAAGATATATCAACGATAGATTTCTTCCAGACAAAGCAATAGATC
TAATTGATGAAGCTGCCTCAAGATTAAATATGGTAATAACTTCAAAACCAGAAGAAATTGATGAGATTGATAGAAAAGTT
TTACAACTAGAAATGGAGAATTTATCCCTAAAAAGAGAATCCGATAATTTTTCTTTAGAAAGGATAAAAAAAATTAATAA
TGAGCTTAAAGATCTCAAGTCTAAACAATCTGAATTAAATATTAAATGGAGAAAAGAGAAAGAAGAAATTGATGAGATTA
GTAATTTAAAAGAAGAAATAGAATCTACACAATTAAAGATAGAACAAGCCAAAAGAAGCTTTGATCTTAATAAAGCAGCA
GAATTAGAATTTGGAACCTTAATTTCATTACAAAAAAAATTAAAATCAAAAAATGAAATTTTGGTAGATTCTTTTAAAAA
TGGTGAAAATAATCTTTTAAGACAGGAAGTAACCTTTGATGATATTGCGGAGGTAGTTTCGAAATGGACCTCAATACCAG
TTAATAATTTAAACCAATCTGAAAAAGACAAACTTTTAAAATTAGAATTAACTCTTAAGGAAAAAATTATTGGCCAAAGT
AATGCTATTTTTGCTGTCGCAAATTCAATAAAAAGATCAAGGACAGGACTCAATGATCCGAATAGACCATTAGCAAGTTT
TTTATTTTTAGGACCAACTGGAGTAGGTAAAACAGAACTTAGCAAAGTAACAGCTGAAACAATATTTGATTCAAGTGATT
CGATTACAAGACTAGATATGTCTGAATACATGGAAAAGCATTCAGTTAGCAAAATCATTGGAGCTCCTCCTGGATATTTA
GGTTTTGAATCCGGAGGTCAATTAACAGAAGCAGTTCGCAAAAATCCTTATTCATTGATTCTCTTAGATGAAATAGAGAA
AGCTCATAAAGATATCTTAGATATTCTTTTGCAAGTGCTTGATGATGGGATTATTACTGATGGTCAAGGCAGAACTATTA
GTTTTAAAAATTCAATTATTGTACTTACAAGTAATTTAGGCAGTCAATCAATAAATGATTTATCTATCAGAAATGAAGAT
AAAAATGAAATCAAAACTATTGTGGATCTTGAATTAAAGAAATTTTTTAAGCCAGAATTCTTAAATCGATTAGATGAAAT
TGTGATTTTCCAAAATTTGGAAATAAATGAATTAAAAGAAATTGCAAACATTCAACTTAAAAATTTAGAAAATAGACTTA
TTAAAAAAGATTTAAAATTAAAAATTTCAGATGAGGCGGTTGAGTACTTAGTCAAAAATAGTTTTGATAATAATTATGGA
GCGAGACCATTAAAGAGGATTATTCAAAATCAAATCACGACAAACATTGCAAACAATATCCTTAATAACATTTATTTAAA
TAAAAAAGAGGTTGATATATTTATTAAGAATGGGAAATTGTTTGTAGAGTAA

Upstream 100 bases:

>100_bases
CATCCATGTGAATGTTTCGAAATAATTAAAGTATTTAATCCTCGCTTTAATGAAAATAGTCCCAACTGAATTTTCAAATT
CTGCCTGGGACTATTTTATT

Downstream 100 bases:

>100_bases
TATTTACGAAAAAATCTTTTTACAGGTCTTAGAACCACTCTGGCAATTCTTCATAATTAGCAGAATTAGATTTATTTTCT
TTTGATTCTGCTTTCCAGCA

Product: ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 843; Mature: 842

Protein sequence:

>843_residues
MSKKIAANNFQQTVDSENLLLTIIKEDSLAKEILKKNEVDIEKIEKDLISLLNSKAKMKNKQKILYIGESLNNIFLKSND
LRVSLNDVVISTEHLLYGLSYDEVCGKLILNKKKIPDFLETIIEMKSNPKIQNNFESPNESLDKFGIDLTKSASEGNLDP
VIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPSSLHNRRLISLDMGSLIAGAKYRGEFEERI
KNVLKKVKSSAGKIILFIDEIHTVVGAGASGGSLDASNLLKPMLARGELRCIGATTINEHKQNIEKDPALERRFQKIKIN
APSVDDTVSILRGLKEKYEVHHSVRISDNALVAAASLSERYINDRFLPDKAIDLIDEAASRLNMVITSKPEEIDEIDRKV
LQLEMENLSLKRESDNFSLERIKKINNELKDLKSKQSELNIKWRKEKEEIDEISNLKEEIESTQLKIEQAKRSFDLNKAA
ELEFGTLISLQKKLKSKNEILVDSFKNGENNLLRQEVTFDDIAEVVSKWTSIPVNNLNQSEKDKLLKLELTLKEKIIGQS
NAIFAVANSIKRSRTGLNDPNRPLASFLFLGPTGVGKTELSKVTAETIFDSSDSITRLDMSEYMEKHSVSKIIGAPPGYL
GFESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTISFKNSIIVLTSNLGSQSINDLSIRNED
KNEIKTIVDLELKKFFKPEFLNRLDEIVIFQNLEINELKEIANIQLKNLENRLIKKDLKLKISDEAVEYLVKNSFDNNYG
ARPLKRIIQNQITTNIANNILNNIYLNKKEVDIFIKNGKLFVE

Sequences:

>Translated_843_residues
MSKKIAANNFQQTVDSENLLLTIIKEDSLAKEILKKNEVDIEKIEKDLISLLNSKAKMKNKQKILYIGESLNNIFLKSND
LRVSLNDVVISTEHLLYGLSYDEVCGKLILNKKKIPDFLETIIEMKSNPKIQNNFESPNESLDKFGIDLTKSASEGNLDP
VIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPSSLHNRRLISLDMGSLIAGAKYRGEFEERI
KNVLKKVKSSAGKIILFIDEIHTVVGAGASGGSLDASNLLKPMLARGELRCIGATTINEHKQNIEKDPALERRFQKIKIN
APSVDDTVSILRGLKEKYEVHHSVRISDNALVAAASLSERYINDRFLPDKAIDLIDEAASRLNMVITSKPEEIDEIDRKV
LQLEMENLSLKRESDNFSLERIKKINNELKDLKSKQSELNIKWRKEKEEIDEISNLKEEIESTQLKIEQAKRSFDLNKAA
ELEFGTLISLQKKLKSKNEILVDSFKNGENNLLRQEVTFDDIAEVVSKWTSIPVNNLNQSEKDKLLKLELTLKEKIIGQS
NAIFAVANSIKRSRTGLNDPNRPLASFLFLGPTGVGKTELSKVTAETIFDSSDSITRLDMSEYMEKHSVSKIIGAPPGYL
GFESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTISFKNSIIVLTSNLGSQSINDLSIRNED
KNEIKTIVDLELKKFFKPEFLNRLDEIVIFQNLEINELKEIANIQLKNLENRLIKKDLKLKISDEAVEYLVKNSFDNNYG
ARPLKRIIQNQITTNIANNILNNIYLNKKEVDIFIKNGKLFVE
>Mature_842_residues
SKKIAANNFQQTVDSENLLLTIIKEDSLAKEILKKNEVDIEKIEKDLISLLNSKAKMKNKQKILYIGESLNNIFLKSNDL
RVSLNDVVISTEHLLYGLSYDEVCGKLILNKKKIPDFLETIIEMKSNPKIQNNFESPNESLDKFGIDLTKSASEGNLDPV
IGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPSSLHNRRLISLDMGSLIAGAKYRGEFEERIK
NVLKKVKSSAGKIILFIDEIHTVVGAGASGGSLDASNLLKPMLARGELRCIGATTINEHKQNIEKDPALERRFQKIKINA
PSVDDTVSILRGLKEKYEVHHSVRISDNALVAAASLSERYINDRFLPDKAIDLIDEAASRLNMVITSKPEEIDEIDRKVL
QLEMENLSLKRESDNFSLERIKKINNELKDLKSKQSELNIKWRKEKEEIDEISNLKEEIESTQLKIEQAKRSFDLNKAAE
LEFGTLISLQKKLKSKNEILVDSFKNGENNLLRQEVTFDDIAEVVSKWTSIPVNNLNQSEKDKLLKLELTLKEKIIGQSN
AIFAVANSIKRSRTGLNDPNRPLASFLFLGPTGVGKTELSKVTAETIFDSSDSITRLDMSEYMEKHSVSKIIGAPPGYLG
FESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTISFKNSIIVLTSNLGSQSINDLSIRNEDK
NEIKTIVDLELKKFFKPEFLNRLDEIVIFQNLEINELKEIANIQLKNLENRLIKKDLKLKISDEAVEYLVKNSFDNNYGA
RPLKRIIQNQITTNIANNILNNIYLNKKEVDIFIKNGKLFVE

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=300, Percent_Identity=37.3333333333333, Blast_Score=198, Evalue=2e-50,
Organism=Escherichia coli, GI1788943, Length=705, Percent_Identity=55.177304964539, Blast_Score=820, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=267, Percent_Identity=54.3071161048689, Blast_Score=288, Evalue=8e-79,
Organism=Saccharomyces cerevisiae, GI6320464, Length=768, Percent_Identity=49.7395833333333, Blast_Score=731, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=779, Percent_Identity=41.7201540436457, Blast_Score=618, Evalue=1e-178,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95122; Mature: 94990

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKIAANNFQQTVDSENLLLTIIKEDSLAKEILKKNEVDIEKIEKDLISLLNSKAKMKN
CCCCCCCCHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
KQKILYIGESLNNIFLKSNDLRVSLNDVVISTEHLLYGLSYDEVCGKLILNKKKIPDFLE
CCEEEEEECCCCCEEEECCCCEEEECCEEEEHHHHHCCCCHHHHHHHHHHCCCCCHHHHH
TIIEMKSNPKIQNNFESPNESLDKFGIDLTKSASEGNLDPVIGRDEEIRRTIQILSRRTK
HHHHHCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
NNPVLIGEPGVGKTAIVEGLAQRIVNGDVPSSLHNRRLISLDMGSLIAGAKYRGEFEERI
CCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCEEEEEEHHHHHHCCHHCCHHHHHH
KNVLKKVKSSAGKIILFIDEIHTVVGAGASGGSLDASNLLKPMLARGELRCIGATTINEH
HHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCHHHHH
KQNIEKDPALERRFQKIKINAPSVDDTVSILRGLKEKYEVHHSVRISDNALVAAASLSER
HHCCCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCEEEHHHHHHH
YINDRFLPDKAIDLIDEAASRLNMVITSKPEEIDEIDRKVLQLEMENLSLKRESDNFSLE
HHCCCCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCEEECCCCCCHHH
RIKKINNELKDLKSKQSELNIKWRKEKEEIDEISNLKEEIESTQLKIEQAKRSFDLNKAA
HHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ELEFGTLISLQKKLKSKNEILVDSFKNGENNLLRQEVTFDDIAEVVSKWTSIPVNNLNQS
CCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
EKDKLLKLELTLKEKIIGQSNAIFAVANSIKRSRTGLNDPNRPLASFLFLGPTGVGKTEL
CCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHEECCCCCCHHHH
SKVTAETIFDSSDSITRLDMSEYMEKHSVSKIIGAPPGYLGFESGGQLTEAVRKNPYSLI
HHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEE
LLDEIEKAHKDILDILLQVLDDGIITDGQGRTISFKNSIIVLTSNLGSQSINDLSIRNED
EHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCC
KNEIKTIVDLELKKFFKPEFLNRLDEIVIFQNLEINELKEIANIQLKNLENRLIKKDLKL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCE
KISDEAVEYLVKNSFDNNYGARPLKRIIQNQITTNIANNILNNIYLNKKEVDIFIKNGKL
EECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEE
FVE
EEC
>Mature Secondary Structure 
SKKIAANNFQQTVDSENLLLTIIKEDSLAKEILKKNEVDIEKIEKDLISLLNSKAKMKN
CCCCCCCHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
KQKILYIGESLNNIFLKSNDLRVSLNDVVISTEHLLYGLSYDEVCGKLILNKKKIPDFLE
CCEEEEEECCCCCEEEECCCCEEEECCEEEEHHHHHCCCCHHHHHHHHHHCCCCCHHHHH
TIIEMKSNPKIQNNFESPNESLDKFGIDLTKSASEGNLDPVIGRDEEIRRTIQILSRRTK
HHHHHCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
NNPVLIGEPGVGKTAIVEGLAQRIVNGDVPSSLHNRRLISLDMGSLIAGAKYRGEFEERI
CCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCEEEEEEHHHHHHCCHHCCHHHHHH
KNVLKKVKSSAGKIILFIDEIHTVVGAGASGGSLDASNLLKPMLARGELRCIGATTINEH
HHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCHHHHH
KQNIEKDPALERRFQKIKINAPSVDDTVSILRGLKEKYEVHHSVRISDNALVAAASLSER
HHCCCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCEEEHHHHHHH
YINDRFLPDKAIDLIDEAASRLNMVITSKPEEIDEIDRKVLQLEMENLSLKRESDNFSLE
HHCCCCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCEEECCCCCCHHH
RIKKINNELKDLKSKQSELNIKWRKEKEEIDEISNLKEEIESTQLKIEQAKRSFDLNKAA
HHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ELEFGTLISLQKKLKSKNEILVDSFKNGENNLLRQEVTFDDIAEVVSKWTSIPVNNLNQS
CCCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
EKDKLLKLELTLKEKIIGQSNAIFAVANSIKRSRTGLNDPNRPLASFLFLGPTGVGKTEL
CCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHEECCCCCCHHHH
SKVTAETIFDSSDSITRLDMSEYMEKHSVSKIIGAPPGYLGFESGGQLTEAVRKNPYSLI
HHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEE
LLDEIEKAHKDILDILLQVLDDGIITDGQGRTISFKNSIIVLTSNLGSQSINDLSIRNED
EHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCC
KNEIKTIVDLELKKFFKPEFLNRLDEIVIFQNLEINELKEIANIQLKNLENRLIKKDLKL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCE
KISDEAVEYLVKNSFDNNYGARPLKRIIQNQITTNIANNILNNIYLNKKEVDIFIKNGKL
EECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEE
FVE
EEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]