| Definition | Prochlorococcus marinus str. MIT 9515, complete genome. |
|---|---|
| Accession | NC_008817 |
| Length | 1,704,176 |
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The map label for this gene is ftsI [H]
Identifier: 123965817
GI number: 123965817
Start: 519339
End: 521090
Strand: Direct
Name: ftsI [H]
Synonym: P9515_05821
Alternate gene names: 123965817
Gene position: 519339-521090 (Clockwise)
Preceding gene: 123965816
Following gene: 123965818
Centisome position: 30.47
GC content: 32.53
Gene sequence:
>1752_bases ATGAAAAGAAATAAGAAAATTGTTAAACTCGCCCCTCTTAAAGCTCGAAGGTTTAAGGTCACGTATATATTTTGTTTGAC ATTAATTTTTGGACTTTTTGGCAGACTTGTAAATCTACAAGTTTTTAGTGCCTCTGACTTACAAAAAAAAGCTAGGTTAA TTCAATTTACTAAAACTATTTCTCTAAGAAGTAGAAGATCAATAGTTGATAGGAATAATAGATTGATTGCTTATGATAAA CCTCTTTATAAATTATGGGCTCATCCAAAATACTTTAACTTCCCTGGAGATCCTACTCAGAGGTTAAGAAGCATTGAAGA GGTAATTAATATATTGTCCCCAATTTTAAATGTAAAAGAAGAAATTCTCCTCTCAAAGTTTGATAATAAAATAACAGGGA TAGAATTACTTGATGAAATAACAGAGAATCAAGCAAAAAAGATCAAAAGCCTTCATATAAGTGGTCTAGATCTAGTGAAA TATTCTCAAAGATATTACCCTCAAAGTAATTTATATTCAAATCTCATTGGTTTTGTTAATCATGATAATAAGGGTTCAGC TGGTTTAGAACTGCACTTGGACAATCAAATTAAAGTATTTAATAAAAGTAATTTGCTAAAGAAAGGTGGAGACGGAACTC CTCTTCCAGATAATTCGGGTCCAAGAGATTTTATTAATGATTATCAGAGCTTAGGTTTAACAATAGATTCAAGATTGCAG AAAGCTTCATTTCAAGCTTTAAATAAACATGTAATGAAGTGGAAGGCAAAGAAAGGCTTCGCAATAGTTATGAATGTTAA TAATGGTGAAATCCTATCGTTAGCGTCAATCCCATCTTATGATCCAAATAAATATTGGGAATATAATTCTGAAATCTTCA AAGGTTGGTATTCTCAAGATTTATTCGAACCTGGCTCGACTTTTAAACCTATAAATCTAGCTTTGGCATTAGAAGAAAAA GTAATTCAAAAAGATGGTTTAGTTGAAGATAGTGGGAAGGTTAATGTTGGAGGATGGACCCTTTCGAATTGGGATAAAAA GGGTAATGGATATATCGATTATCCAAAAGTTTTACAAGTTTCAAGTAATGTTGGGATGGTAAAAATAATGCAAAACTTAC CGCCTAAAACCTATTGGGATTGGCTGAATAAATTAGGAATTAGTAAAAATATAAAGACAGATTTGTTTGAATCTACGGCA GGTCATTTAAAGTCAAAAGATATATTTGTTAATCAATCAATTGAGCCGGCAGTTGCTTCTTTTGGAAAGGGGTTTTCCAT TTCGCCATTGAAATTAGCTCAACTTCATGCTGTCTTAGCTAATGGGGGGGTTGAAGTGATTCCTCATGTAACTTTAAATT TCAAAGATAATCTTAAAAATAAATCACAAGAAGAAATCTTCTCTAATGAGGTCTCTAGAACTGTTCTTGAATGGATGGAA AGTGTTGTTGATAAGGGTAGTGGAATTGGCGCAAAAATTGAGGGCTACAGAATTGGAGGGAAAACTGGAACCTCTCAGAA GGCGATTAATGGAAGATATACAAGTAAGAAGGTTTGTAGTTTTGTTGCTACTTTTCCTATAAATAATCCTAGGTATGTTG TACTTGTTGTCATTGATGAGCCATCTAAAGCCTACGCTTATGGCTCAACAGTTGCTGTTCCAGTTGCAAAAGAAATTATC GAAAGTCTAATTGTTATTGAAAAAATACCCCCGCAAATTGAAAAGAATAGATTAATTGTTAAAAAACCATGA
Upstream 100 bases:
>100_bases TAATTTACCTCGATAAGCAAATTCCTAAGCAGAAAAAAAATGAATTAATTAATAATATTCGAGATGGATTAAAGGATAGT CAATACCAAAGAGGCTATTA
Downstream 100 bases:
>100_bases AATTATCCGATTTTAGGTTTAAATAGTTGATATTTTAATGAATTCATTTTGAATTGAGGCTAACTTAAAGGTATACATGA TTATCTAAAAATGAAATCAA
Product: peptidoglycan synthetase
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 583; Mature: 583
Protein sequence:
>583_residues MKRNKKIVKLAPLKARRFKVTYIFCLTLIFGLFGRLVNLQVFSASDLQKKARLIQFTKTISLRSRRSIVDRNNRLIAYDK PLYKLWAHPKYFNFPGDPTQRLRSIEEVINILSPILNVKEEILLSKFDNKITGIELLDEITENQAKKIKSLHISGLDLVK YSQRYYPQSNLYSNLIGFVNHDNKGSAGLELHLDNQIKVFNKSNLLKKGGDGTPLPDNSGPRDFINDYQSLGLTIDSRLQ KASFQALNKHVMKWKAKKGFAIVMNVNNGEILSLASIPSYDPNKYWEYNSEIFKGWYSQDLFEPGSTFKPINLALALEEK VIQKDGLVEDSGKVNVGGWTLSNWDKKGNGYIDYPKVLQVSSNVGMVKIMQNLPPKTYWDWLNKLGISKNIKTDLFESTA GHLKSKDIFVNQSIEPAVASFGKGFSISPLKLAQLHAVLANGGVEVIPHVTLNFKDNLKNKSQEEIFSNEVSRTVLEWME SVVDKGSGIGAKIEGYRIGGKTGTSQKAINGRYTSKKVCSFVATFPINNPRYVVLVVIDEPSKAYAYGSTVAVPVAKEII ESLIVIEKIPPQIEKNRLIVKKP
Sequences:
>Translated_583_residues MKRNKKIVKLAPLKARRFKVTYIFCLTLIFGLFGRLVNLQVFSASDLQKKARLIQFTKTISLRSRRSIVDRNNRLIAYDK PLYKLWAHPKYFNFPGDPTQRLRSIEEVINILSPILNVKEEILLSKFDNKITGIELLDEITENQAKKIKSLHISGLDLVK YSQRYYPQSNLYSNLIGFVNHDNKGSAGLELHLDNQIKVFNKSNLLKKGGDGTPLPDNSGPRDFINDYQSLGLTIDSRLQ KASFQALNKHVMKWKAKKGFAIVMNVNNGEILSLASIPSYDPNKYWEYNSEIFKGWYSQDLFEPGSTFKPINLALALEEK VIQKDGLVEDSGKVNVGGWTLSNWDKKGNGYIDYPKVLQVSSNVGMVKIMQNLPPKTYWDWLNKLGISKNIKTDLFESTA GHLKSKDIFVNQSIEPAVASFGKGFSISPLKLAQLHAVLANGGVEVIPHVTLNFKDNLKNKSQEEIFSNEVSRTVLEWME SVVDKGSGIGAKIEGYRIGGKTGTSQKAINGRYTSKKVCSFVATFPINNPRYVVLVVIDEPSKAYAYGSTVAVPVAKEII ESLIVIEKIPPQIEKNRLIVKKP >Mature_583_residues MKRNKKIVKLAPLKARRFKVTYIFCLTLIFGLFGRLVNLQVFSASDLQKKARLIQFTKTISLRSRRSIVDRNNRLIAYDK PLYKLWAHPKYFNFPGDPTQRLRSIEEVINILSPILNVKEEILLSKFDNKITGIELLDEITENQAKKIKSLHISGLDLVK YSQRYYPQSNLYSNLIGFVNHDNKGSAGLELHLDNQIKVFNKSNLLKKGGDGTPLPDNSGPRDFINDYQSLGLTIDSRLQ KASFQALNKHVMKWKAKKGFAIVMNVNNGEILSLASIPSYDPNKYWEYNSEIFKGWYSQDLFEPGSTFKPINLALALEEK VIQKDGLVEDSGKVNVGGWTLSNWDKKGNGYIDYPKVLQVSSNVGMVKIMQNLPPKTYWDWLNKLGISKNIKTDLFESTA GHLKSKDIFVNQSIEPAVASFGKGFSISPLKLAQLHAVLANGGVEVIPHVTLNFKDNLKNKSQEEIFSNEVSRTVLEWME SVVDKGSGIGAKIEGYRIGGKTGTSQKAINGRYTSKKVCSFVATFPINNPRYVVLVVIDEPSKAYAYGSTVAVPVAKEII ESLIVIEKIPPQIEKNRLIVKKP
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=570, Percent_Identity=30, Blast_Score=231, Evalue=7e-62, Organism=Escherichia coli, GI1786854, Length=616, Percent_Identity=20.2922077922078, Blast_Score=110, Evalue=3e-25,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 65620; Mature: 65620
Theoretical pI: Translated: 10.22; Mature: 10.22
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.0 %Met (Translated Protein) 1.4 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.0 %Met (Mature Protein) 1.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRNKKIVKLAPLKARRFKVTYIFCLTLIFGLFGRLVNLQVFSASDLQKKARLIQFTKTI CCCCCCEEEEECCCCHHEEHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHH SLRSRRSIVDRNNRLIAYDKPLYKLWAHPKYFNFPGDPTQRLRSIEEVINILSPILNVKE HHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH EILLSKFDNKITGIELLDEITENQAKKIKSLHISGLDLVKYSQRYYPQSNLYSNLIGFVN HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHEE HDNKGSAGLELHLDNQIKVFNKSNLLKKGGDGTPLPDNSGPRDFINDYQSLGLTIDSRLQ CCCCCCCEEEEEECCEEEEECCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHH KASFQALNKHVMKWKAKKGFAIVMNVNNGEILSLASIPSYDPNKYWEYNSEIFKGWYSQD HHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHH LFEPGSTFKPINLALALEEKVIQKDGLVEDSGKVNVGGWTLSNWDKKGNGYIDYPKVLQV HCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCEEEECCEEECCCCCCCCCCCCCCHHEEE SSNVGMVKIMQNLPPKTYWDWLNKLGISKNIKTDLFESTAGHLKSKDIFVNQSIEPAVAS CCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHHH FGKGFSISPLKLAQLHAVLANGGVEVIPHVTLNFKDNLKNKSQEEIFSNEVSRTVLEWME CCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHH SVVDKGSGIGAKIEGYRIGGKTGTSQKAINGRYTSKKVCSFVATFPINNPRYVVLVVIDE HHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECC PSKAYAYGSTVAVPVAKEIIESLIVIEKIPPQIEKNRLIVKKP CCCCEECCCEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC >Mature Secondary Structure MKRNKKIVKLAPLKARRFKVTYIFCLTLIFGLFGRLVNLQVFSASDLQKKARLIQFTKTI CCCCCCEEEEECCCCHHEEHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHH SLRSRRSIVDRNNRLIAYDKPLYKLWAHPKYFNFPGDPTQRLRSIEEVINILSPILNVKE HHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH EILLSKFDNKITGIELLDEITENQAKKIKSLHISGLDLVKYSQRYYPQSNLYSNLIGFVN HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHEE HDNKGSAGLELHLDNQIKVFNKSNLLKKGGDGTPLPDNSGPRDFINDYQSLGLTIDSRLQ CCCCCCCEEEEEECCEEEEECCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHH KASFQALNKHVMKWKAKKGFAIVMNVNNGEILSLASIPSYDPNKYWEYNSEIFKGWYSQD HHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHH LFEPGSTFKPINLALALEEKVIQKDGLVEDSGKVNVGGWTLSNWDKKGNGYIDYPKVLQV HCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCEEEECCEEECCCCCCCCCCCCCCHHEEE SSNVGMVKIMQNLPPKTYWDWLNKLGISKNIKTDLFESTAGHLKSKDIFVNQSIEPAVAS CCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHHH FGKGFSISPLKLAQLHAVLANGGVEVIPHVTLNFKDNLKNKSQEEIFSNEVSRTVLEWME CCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHH SVVDKGSGIGAKIEGYRIGGKTGTSQKAINGRYTSKKVCSFVATFPINNPRYVVLVVIDE HHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECC PSKAYAYGSTVAVPVAKEIIESLIVIEKIPPQIEKNRLIVKKP CCCCEECCCEEEHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]