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The map label for this gene is ppa [H]

Identifier: 123965810

GI number: 123965810

Start: 513185

End: 513733

Strand: Direct

Name: ppa [H]

Synonym: P9515_05751

Alternate gene names: 123965810

Gene position: 513185-513733 (Clockwise)

Preceding gene: 123965809

Following gene: 123965811

Centisome position: 30.11

GC content: 33.7

Gene sequence:

>549_bases
ATGGATCTTAGTTTGATACCTCCATCTCCAACGAAGGGTATAGTAAATTTAGTGGTTGAAATACCAGCTGGGAGCAGGAA
TAAATACGAATATTGTTCTCAAGCTGGAATTATGGCACTTGATAGAATTTTACATTCTTCAGTAAGGTACCCCTTTGATT
ATGGTTTTATTCCAAATACACTTGCTGATGACGGGGCTCCGCTTGATGCAATGGTAATAATGGATGAACCAACATTTGCA
GGTTGTTTAATTAAAGCAAGACCTATAGGAGTTTTAGATATGCATGATTGTGGGCATTATGATGGCAAACTTTTATGCGT
TCCTGTAGCTAATCCAAGACAAGATAATATAACTAGTATTAATCAAATAGCTCCTAATCAATTAGAAGATGTCGCAGAAT
TTTTTAGAACAAGTAAAGGTTTAGACGGAAGAACAGTTCAAATAGATGGTTGGAGAGATTTTGAAGTGATTGAGGAACTT
TTAAGAAAATGTACATCTTCAAAAAAGAAAACCTTTAAAGTTCTAAAAAAATCATCAATAGTTAAATAA

Upstream 100 bases:

>100_bases
ATTGCTTTTCTTACAATTTTATTGCCTTCAATAAGTATTTTGCTTGGTAGACCTTTATCTCAAGGAAATGAGATTACTTC
TTTTCACTTAATTAAAAAAG

Downstream 100 bases:

>100_bases
ATTGAAAAAAGTAATTTTTTATAGCTATCCAAAATGTTCAACATGCAGAAAAGCATCAAAATGGCTTGATCAAAATAATA
TAAACTATAAATTTATAGAT

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MDLSLIPPSPTKGIVNLVVEIPAGSRNKYEYCSQAGIMALDRILHSSVRYPFDYGFIPNTLADDGAPLDAMVIMDEPTFA
GCLIKARPIGVLDMHDCGHYDGKLLCVPVANPRQDNITSINQIAPNQLEDVAEFFRTSKGLDGRTVQIDGWRDFEVIEEL
LRKCTSSKKKTFKVLKKSSIVK

Sequences:

>Translated_182_residues
MDLSLIPPSPTKGIVNLVVEIPAGSRNKYEYCSQAGIMALDRILHSSVRYPFDYGFIPNTLADDGAPLDAMVIMDEPTFA
GCLIKARPIGVLDMHDCGHYDGKLLCVPVANPRQDNITSINQIAPNQLEDVAEFFRTSKGLDGRTVQIDGWRDFEVIEEL
LRKCTSSKKKTFKVLKKSSIVK
>Mature_182_residues
MDLSLIPPSPTKGIVNLVVEIPAGSRNKYEYCSQAGIMALDRILHSSVRYPFDYGFIPNTLADDGAPLDAMVIMDEPTFA
GCLIKARPIGVLDMHDCGHYDGKLLCVPVANPRQDNITSINQIAPNQLEDVAEFFRTSKGLDGRTVQIDGWRDFEVIEEL
LRKCTSSKKKTFKVLKKSSIVK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=161, Percent_Identity=33.5403726708075, Blast_Score=92, Evalue=1e-20,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20187; Mature: 20187

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSLIPPSPTKGIVNLVVEIPAGSRNKYEYCSQAGIMALDRILHSSVRYPFDYGFIPNT
CCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LADDGAPLDAMVIMDEPTFAGCLIKARPIGVLDMHDCGHYDGKLLCVPVANPRQDNITSI
CCCCCCCCEEEEEECCCCCCEEEEECCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCHH
NQIAPNQLEDVAEFFRTSKGLDGRTVQIDGWRDFEVIEELLRKCTSSKKKTFKVLKKSSI
HHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCC
VK
CC
>Mature Secondary Structure
MDLSLIPPSPTKGIVNLVVEIPAGSRNKYEYCSQAGIMALDRILHSSVRYPFDYGFIPNT
CCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LADDGAPLDAMVIMDEPTFAGCLIKARPIGVLDMHDCGHYDGKLLCVPVANPRQDNITSI
CCCCCCCCEEEEEECCCCCCEEEEECCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCHH
NQIAPNQLEDVAEFFRTSKGLDGRTVQIDGWRDFEVIEELLRKCTSSKKKTFKVLKKSSI
HHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]