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The map label for this gene is map [C]

Identifier: 123965775

GI number: 123965775

Start: 481963

End: 482802

Strand: Direct

Name: map [C]

Synonym: P9515_05401

Alternate gene names: 123965775

Gene position: 481963-482802 (Clockwise)

Preceding gene: 123965771

Following gene: 123965777

Centisome position: 28.28

GC content: 34.64

Gene sequence:

>840_bases
ATGAAACATTTTGCAGATCTTTTATTAAATAAAAATAATTCAAGATCTAACGATCAAGTCCCTTTTATTCAAAGAAGAAG
AGGAATAGAAATAAAGTCTTCGAGGGAAATAAAATTAATGAAGAAATCTAGCAGGATCGTAGCAACTGTTTTGCGAGAAA
TAAATGACTTGATAGAACCTGGAATGAGTACAAAAGATTTAGATGATTTTGCAGAAAAGAGAATTAGAGAAATGGGCGCA
GCGCCAAGTTTTAAGGGTTATCATGGTTTCCCATCCAGTATTTGTGCCAGTATAAATAATGAAGTTGTGCACGGCATTCC
AAATAAAAATGTAACAATTAAAGATGGAGATCTTGTGAAAATTGATACAGGAGCTTATTTAGATGGCTTTCACGGTGATA
GTTGCATCACTATTTGTGTTGGTCAAGTAAGTGATCAAGCCAAAAAACTTAGTGAAGTAGCCTTAGAAGCTTTATTCTCA
GGACTTTCGAAAATTAAATCGGGAAATACACTGCTTGATGTGGCTGGAGCTATTGAGGATGTTGTGAGATTAAATGGGTT
TAGTGTTGTTGAAGACTATACAGGTCATGGGGTGGGACGAAATCTTCACGAAGAACCATCTGTTTTTAATTTTCGAACTA
ATGATTTACCGAATATCATTCTTCGTGAGGGGATGACGTTGGCTGTTGAACCTATCGTTAATCAAGGCAGTAAGTTTTGT
AAAACTTTAAATGACAAATGGACAGTAATAACAAAAGATGGGAAATTATCAGCACAATGGGAACATACAATTGTCGTAAT
GAAAGATGGTATTGAAATATTGACAGACAGAGAATTTTAA

Upstream 100 bases:

>100_bases
TTAATAAAATTCATTTTCTGTTTTCTTACTGATAGATTAAAATGGCCAAGCAGTCTATGGCTATTTTGATGATATTTACC
TATTTCCATTATTTATTCCA

Downstream 100 bases:

>100_bases
CTACTAACCTTTGATATTATTAGAAGCTTACAATACAAAAAAATGTATAACTCTTTTAAAGGAAAAAGAATGTATGAAAG
TGGATTTGGACTAACAATAA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKHFADLLLNKNNSRSNDQVPFIQRRRGIEIKSSREIKLMKKSSRIVATVLREINDLIEPGMSTKDLDDFAEKRIREMGA
APSFKGYHGFPSSICASINNEVVHGIPNKNVTIKDGDLVKIDTGAYLDGFHGDSCITICVGQVSDQAKKLSEVALEALFS
GLSKIKSGNTLLDVAGAIEDVVRLNGFSVVEDYTGHGVGRNLHEEPSVFNFRTNDLPNIILREGMTLAVEPIVNQGSKFC
KTLNDKWTVITKDGKLSAQWEHTIVVMKDGIEILTDREF

Sequences:

>Translated_279_residues
MKHFADLLLNKNNSRSNDQVPFIQRRRGIEIKSSREIKLMKKSSRIVATVLREINDLIEPGMSTKDLDDFAEKRIREMGA
APSFKGYHGFPSSICASINNEVVHGIPNKNVTIKDGDLVKIDTGAYLDGFHGDSCITICVGQVSDQAKKLSEVALEALFS
GLSKIKSGNTLLDVAGAIEDVVRLNGFSVVEDYTGHGVGRNLHEEPSVFNFRTNDLPNIILREGMTLAVEPIVNQGSKFC
KTLNDKWTVITKDGKLSAQWEHTIVVMKDGIEILTDREF
>Mature_279_residues
MKHFADLLLNKNNSRSNDQVPFIQRRRGIEIKSSREIKLMKKSSRIVATVLREINDLIEPGMSTKDLDDFAEKRIREMGA
APSFKGYHGFPSSICASINNEVVHGIPNKNVTIKDGDLVKIDTGAYLDGFHGDSCITICVGQVSDQAKKLSEVALEALFS
GLSKIKSGNTLLDVAGAIEDVVRLNGFSVVEDYTGHGVGRNLHEEPSVFNFRTNDLPNIILREGMTLAVEPIVNQGSKFC
KTLNDKWTVITKDGKLSAQWEHTIVVMKDGIEILTDREF

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=35.0806451612903, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI164420681, Length=249, Percent_Identity=34.9397590361446, Blast_Score=169, Evalue=3e-42,
Organism=Escherichia coli, GI1786364, Length=252, Percent_Identity=43.6507936507937, Blast_Score=218, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI71996291, Length=253, Percent_Identity=33.596837944664, Blast_Score=161, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6323273, Length=254, Percent_Identity=36.6141732283465, Blast_Score=173, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=37.8048780487805, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21355531, Length=253, Percent_Identity=37.1541501976285, Blast_Score=168, Evalue=4e-42,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30918; Mature: 30918

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFADLLLNKNNSRSNDQVPFIQRRRGIEIKSSREIKLMKKSSRIVATVLREINDLIEP
CCHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCC
GMSTKDLDDFAEKRIREMGAAPSFKGYHGFPSSICASINNEVVHGIPNKNVTIKDGDLVK
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCEEEECCCEEE
IDTGAYLDGFHGDSCITICVGQVSDQAKKLSEVALEALFSGLSKIKSGNTLLDVAGAIED
ECCCCEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
VVRLNGFSVVEDYTGHGVGRNLHEEPSVFNFRTNDLPNIILREGMTLAVEPIVNQGSKFC
HHHHCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCEEEEHHHHHCCHHHH
KTLNDKWTVITKDGKLSAQWEHTIVVMKDGIEILTDREF
HHCCCCEEEEEECCCEEEEECEEEEEEECCEEEECCCCC
>Mature Secondary Structure
MKHFADLLLNKNNSRSNDQVPFIQRRRGIEIKSSREIKLMKKSSRIVATVLREINDLIEP
CCHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCC
GMSTKDLDDFAEKRIREMGAAPSFKGYHGFPSSICASINNEVVHGIPNKNVTIKDGDLVK
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCEEEECCCEEE
IDTGAYLDGFHGDSCITICVGQVSDQAKKLSEVALEALFSGLSKIKSGNTLLDVAGAIED
ECCCCEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
VVRLNGFSVVEDYTGHGVGRNLHEEPSVFNFRTNDLPNIILREGMTLAVEPIVNQGSKFC
HHHHCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCEEEEHHHHHCCHHHH
KTLNDKWTVITKDGKLSAQWEHTIVVMKDGIEILTDREF
HHCCCCEEEEEECCCEEEEECEEEEEEECCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]