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The map label for this gene is engA

Identifier: 123965688

GI number: 123965688

Start: 402957

End: 404333

Strand: Direct

Name: engA

Synonym: P9515_04531

Alternate gene names: 123965688

Gene position: 402957-404333 (Clockwise)

Preceding gene: 123965687

Following gene: 123965689

Centisome position: 23.65

GC content: 33.99

Gene sequence:

>1377_bases
TTGACTCTTCCATCAATAGCAATAATAGGAAGACCCAATGTTGGTAAATCGACCTTAGTTAATAGGTTATGCCAAAGTAA
TGATGCGATTGTATTTGATAAACCAGGAGTTACTAGAGATAGGACTTATCAAAACGCTTCTTGGGGTGGAAAGGAATTTC
AAGTTGTTGATACAGGAGGACTAGTCTTTGAAGATGATAGTGAATTCCTTCCTGAGATTCGTACTCAAGTTTTTCTAGCA
TTAGAGGAGGCTTCTATTGCTTTATTTGTAGTTGATGGAAATCAAGGTGTAACTACGGGAGATTTATCAATTGCAAAATG
GTTGAGGAATTCAGATTGTAAAACAATTGTTGCAGTAAATAAATGTGAATCTTTATCTTTAGGGATTTCTATGGCCTCTG
AATTCTGGAAATTAGGTTTAGGGGAACCTTATCCTGTATCTGCTATTCATGGCTCTGGAACTGGAGATCTTTTAGACCTT
GTTATTGATGAACTTCCTAAAGATTTTGATGTTGAGGATAAAGAAGATAAAGTAATGATGTCCATAATTGGAAGACCAAA
TGTTGGAAAGTCTAGTTTACTAAATGCTATCTGCGGAGAAAAAAGAGCAATAGTTAGTGATATAAGCGGGACAACAACTG
ATTCTATAGATACTCTAATAAAGAAAAATTCCCATCTTTGGAAAATAGTTGATACTGCTGGAATAAGAAGAAAAAAAAAT
GTAAAATATGGTACTGAATTCTTTGGTATTAACAGAGCTTTTAAATCTATTGATAGAAGCGATGTTTGCGTCTTGGTTAT
AGATGCTATTGATGGTGTTACTGATCAAGATCAGAAATTGGCAGGGCGCATAGAAGAGCAAGGGAGAGCATGCGTAATTG
TTGTGAACAAATGGGATCTTGTAGAGAAAAACAATTCTACAATCTATCAAGTAGAGAAAGAACTCAGATCAAAATTATAT
TTTTTGCATTGGTCAAAAATGATTTTTATATCAGCTTTGACTGGTCAAAGAGTTGAAAATATTTTTGAGCATGCTCTTAA
TGCTGTAACCCAACATAGAATGAGAGTCACAACATCTGTTGTTAATGAAGTTCTTAAGGAGGCTCTTGGCTGGAAAAGTC
CTCCAACTAAGAGAAGCGGTAAACAAGGAAGACTTTACTATGGCACTCAAGTAAAAAACCAGCCTCCAACTTTTACCCTT
TTTGTTAATGATCCCAAATTATTTGGAATAACATATAGAAGATATATAGAAAAACAAATTAGATTAAATCTCGGCTTTGA
AGGTTCTCCAATAATTCTACTTTGGAGAGGAAAGCAGAAAAGAGACTTAGAAAAGGAGACATCAAAAAAGAATATTAATA
TTATTCAAAAAGATTAA

Upstream 100 bases:

>100_bases
ACATAAAGGAGATCCTGAAATTAAATAAATTTTCTTGTTTAGAGTAAAAGATCTTATTGAGGGTATAGTTATACTAGATC
TGATTTTTTAAGGGGTATAA

Downstream 100 bases:

>100_bases
TGAATATTCTTACTAAATTTTCTATTGGACAATATGTTGATGGGAATAGAAGTTGGTTAAGAATTATCGACAGTAGATTA
AAAATAATTGCAGTATTGAT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTLPSIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQVVDTGGLVFEDDSEFLPEIRTQVFLA
LEEASIALFVVDGNQGVTTGDLSIAKWLRNSDCKTIVAVNKCESLSLGISMASEFWKLGLGEPYPVSAIHGSGTGDLLDL
VIDELPKDFDVEDKEDKVMMSIIGRPNVGKSSLLNAICGEKRAIVSDISGTTTDSIDTLIKKNSHLWKIVDTAGIRRKKN
VKYGTEFFGINRAFKSIDRSDVCVLVIDAIDGVTDQDQKLAGRIEEQGRACVIVVNKWDLVEKNNSTIYQVEKELRSKLY
FLHWSKMIFISALTGQRVENIFEHALNAVTQHRMRVTTSVVNEVLKEALGWKSPPTKRSGKQGRLYYGTQVKNQPPTFTL
FVNDPKLFGITYRRYIEKQIRLNLGFEGSPIILLWRGKQKRDLEKETSKKNINIIQKD

Sequences:

>Translated_458_residues
MTLPSIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQVVDTGGLVFEDDSEFLPEIRTQVFLA
LEEASIALFVVDGNQGVTTGDLSIAKWLRNSDCKTIVAVNKCESLSLGISMASEFWKLGLGEPYPVSAIHGSGTGDLLDL
VIDELPKDFDVEDKEDKVMMSIIGRPNVGKSSLLNAICGEKRAIVSDISGTTTDSIDTLIKKNSHLWKIVDTAGIRRKKN
VKYGTEFFGINRAFKSIDRSDVCVLVIDAIDGVTDQDQKLAGRIEEQGRACVIVVNKWDLVEKNNSTIYQVEKELRSKLY
FLHWSKMIFISALTGQRVENIFEHALNAVTQHRMRVTTSVVNEVLKEALGWKSPPTKRSGKQGRLYYGTQVKNQPPTFTL
FVNDPKLFGITYRRYIEKQIRLNLGFEGSPIILLWRGKQKRDLEKETSKKNINIIQKD
>Mature_457_residues
TLPSIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQVVDTGGLVFEDDSEFLPEIRTQVFLAL
EEASIALFVVDGNQGVTTGDLSIAKWLRNSDCKTIVAVNKCESLSLGISMASEFWKLGLGEPYPVSAIHGSGTGDLLDLV
IDELPKDFDVEDKEDKVMMSIIGRPNVGKSSLLNAICGEKRAIVSDISGTTTDSIDTLIKKNSHLWKIVDTAGIRRKKNV
KYGTEFFGINRAFKSIDRSDVCVLVIDAIDGVTDQDQKLAGRIEEQGRACVIVVNKWDLVEKNNSTIYQVEKELRSKLYF
LHWSKMIFISALTGQRVENIFEHALNAVTQHRMRVTTSVVNEVLKEALGWKSPPTKRSGKQGRLYYGTQVKNQPPTFTLF
VNDPKLFGITYRRYIEKQIRLNLGFEGSPIILLWRGKQKRDLEKETSKKNINIIQKD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=459, Percent_Identity=37.6906318082789, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI2367268, Length=87, Percent_Identity=43.6781609195402, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17507259, Length=87, Percent_Identity=45.9770114942529, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=148, Percent_Identity=37.8378378378378, Blast_Score=90, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_PROM5 (A2BV51)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001010769.1
- ProteinModelPortal:   A2BV51
- SMR:   A2BV51
- STRING:   A2BV51
- GeneID:   4719277
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_04531
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   PMAR167542:P9515ORF_0486-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 51294; Mature: 51163

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPSIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQVVDTGG
CCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCC
LVFEDDSEFLPEIRTQVFLALEEASIALFVVDGNQGVTTGDLSIAKWLRNSDCKTIVAVN
EEEECCHHHHHHHHHHHEEEEECCCEEEEEEECCCCCEECCHHHHHHHCCCCCCEEEEEE
KCESLSLGISMASEFWKLGLGEPYPVSAIHGSGTGDLLDLVIDELPKDFDVEDKEDKVMM
CCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEE
SIIGRPNVGKSSLLNAICGEKRAIVSDISGTTTDSIDTLIKKNSHLWKIVDTAGIRRKKN
EECCCCCCCHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCC
VKYGTEFFGINRAFKSIDRSDVCVLVIDAIDGVTDQDQKLAGRIEEQGRACVIVVNKWDL
CCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCEE
VEKNNSTIYQVEKELRSKLYFLHWSKMIFISALTGQRVENIFEHALNAVTQHRMRVTTSV
EECCCCCHHHHHHHHHHHEEEEEEHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNEVLKEALGWKSPPTKRSGKQGRLYYGTQVKNQPPTFTLFVNDPKLFGITYRRYIEKQI
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHH
RLNLGFEGSPIILLWRGKQKRDLEKETSKKNINIIQKD
EEEECCCCCCEEEEECCCCCCCHHHHHCCCCCEEEECC
>Mature Secondary Structure 
TLPSIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQVVDTGG
CCCCEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCC
LVFEDDSEFLPEIRTQVFLALEEASIALFVVDGNQGVTTGDLSIAKWLRNSDCKTIVAVN
EEEECCHHHHHHHHHHHEEEEECCCEEEEEEECCCCCEECCHHHHHHHCCCCCCEEEEEE
KCESLSLGISMASEFWKLGLGEPYPVSAIHGSGTGDLLDLVIDELPKDFDVEDKEDKVMM
CCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEE
SIIGRPNVGKSSLLNAICGEKRAIVSDISGTTTDSIDTLIKKNSHLWKIVDTAGIRRKKN
EECCCCCCCHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCC
VKYGTEFFGINRAFKSIDRSDVCVLVIDAIDGVTDQDQKLAGRIEEQGRACVIVVNKWDL
CCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCEE
VEKNNSTIYQVEKELRSKLYFLHWSKMIFISALTGQRVENIFEHALNAVTQHRMRVTTSV
EECCCCCHHHHHHHHHHHEEEEEEHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNEVLKEALGWKSPPTKRSGKQGRLYYGTQVKNQPPTFTLFVNDPKLFGITYRRYIEKQI
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHH
RLNLGFEGSPIILLWRGKQKRDLEKETSKKNINIIQKD
EEEECCCCCCEEEEECCCCCCCHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA