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The map label for this gene is aroQ

Identifier: 123965684

GI number: 123965684

Start: 400564

End: 401004

Strand: Direct

Name: aroQ

Synonym: P9515_04491

Alternate gene names: 123965684

Gene position: 400564-401004 (Clockwise)

Preceding gene: 123965673

Following gene: 123965685

Centisome position: 23.5

GC content: 27.21

Gene sequence:

>441_bases
ATGAATATTTTATTAATAAATGGACCAAATTTAAATCTATTAGGTACTAGAGAACCTGAAATATATGGTAGTAAAACCTT
GAATGATATCGAAAATGACTTATCTAGTATTGCTAACGATAAAATAATTAATCTTGAATGTTTCCAAAGTAATCATGAGG
GTGAAATTGTAGATAAAATTCAGGATTCTATTAAGAATGTTCAAGGAATACTTATAAACGCAGGAGCTTTTACTCATACT
TCAATATCAATTAGGGATGCTTTGATCGGCTCTAAAATTCCATTTGTTGAATTACACATTTCAAATATATTTAGTAGAGA
AGAATTTCGAAAAGAATCTTTTTTGACAGATAAGGCAATTGGAATTATTAGCGGATTTGGTATATCAAGCTATTCTCTTG
GTTTATACGGAATTATAGAGTATTTAAAAAATAAAAAGTAA

Upstream 100 bases:

>100_bases
CACCATAAAAATTTATCAGTTAATGGTCACTTTGTGTGAAAATGTTTTGGTTTTTTTGTTTCTTTCTAGATAGGATTTAG
AAGAAATTAGTTTCTTTTTA

Downstream 100 bases:

>100_bases
ATGATAGTTGAAAATAAAAGACCTGATTTTCAAATAAAACATTTAACATCGTCAACTTCAGATGTTTGGATTAAATTAGC
TTTGTCTAATCCTATCGATA

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MNILLINGPNLNLLGTREPEIYGSKTLNDIENDLSSIANDKIINLECFQSNHEGEIVDKIQDSIKNVQGILINAGAFTHT
SISIRDALIGSKIPFVELHISNIFSREEFRKESFLTDKAIGIISGFGISSYSLGLYGIIEYLKNKK

Sequences:

>Translated_146_residues
MNILLINGPNLNLLGTREPEIYGSKTLNDIENDLSSIANDKIINLECFQSNHEGEIVDKIQDSIKNVQGILINAGAFTHT
SISIRDALIGSKIPFVELHISNIFSREEFRKESFLTDKAIGIISGFGISSYSLGLYGIIEYLKNKK
>Mature_146_residues
MNILLINGPNLNLLGTREPEIYGSKTLNDIENDLSSIANDKIINLECFQSNHEGEIVDKIQDSIKNVQGILINAGAFTHT
SISIRDALIGSKIPFVELHISNIFSREEFRKESFLTDKAIGIISGFGISSYSLGLYGIIEYLKNKK

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_PROM5 (A2BV47)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001010765.1
- ProteinModelPortal:   A2BV47
- SMR:   A2BV47
- STRING:   A2BV47
- GeneID:   4719273
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_04491
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   PMAR167542:P9515ORF_0482-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16201; Mature: 16201

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 99-99 BINDING 73-73 BINDING 79-79 BINDING 86-86 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILLINGPNLNLLGTREPEIYGSKTLNDIENDLSSIANDKIINLECFQSNHEGEIVDKI
CEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHH
QDSIKNVQGILINAGAFTHTSISIRDALIGSKIPFVELHISNIFSREEFRKESFLTDKAI
HHHHHHHCEEEEECCCEEECEEEHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHH
GIISGFGISSYSLGLYGIIEYLKNKK
HHEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNILLINGPNLNLLGTREPEIYGSKTLNDIENDLSSIANDKIINLECFQSNHEGEIVDKI
CEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHH
QDSIKNVQGILINAGAFTHTSISIRDALIGSKIPFVELHISNIFSREEFRKESFLTDKAI
HHHHHHHCEEEEECCCEEECEEEHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHH
GIISGFGISSYSLGLYGIIEYLKNKK
HHEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA