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The map label for this gene is dcm [H]

Identifier: 123965679

GI number: 123965679

Start: 393777

End: 395846

Strand: Reverse

Name: dcm [H]

Synonym: P9515_04441

Alternate gene names: 123965679

Gene position: 395846-393777 (Counterclockwise)

Preceding gene: 123965680

Following gene: 123965678

Centisome position: 23.23

GC content: 35.02

Gene sequence:

>2070_bases
ATGATACATAAGAATGCAGTAGGAAAAATTGATCCACATAGATTAACTCCTGTCAGAGGTCCTTCAACAGAACTTGATCC
TCATATTGATTCATGCGAATTTGATGAACTTCCTGGTTATGCGGCAAAAGTTCGTAGTCTTAAAAAAGACCCAAACTTTG
CTGTTGATCTTTTTTCAGGTGCTGGTGGTTTAAGTCTTGGGCTTCATCGAGCAAATTTTGATGTAATTCTTGCATGTGAT
ATTCGAAATGATTCAATAATGACTCACAGGCATCATTTTGGCGGTTGCTCGTATGAATGTGATTTAAGTAAAAGAAAGGT
TGTTAATGAAATTGCTGACAAACTTAACGAATGTGGAGAAATTTCACTTATTGCAGGTGGGCCTCCATGTCAGCCTTTTT
CGAGAAATATCAAATGGAGGAAACATAATGAAGAAGTTTCGGCTCAACATCAGGAACTTAATGAAGATAGAAGAGAATTA
TGGGAATCATTTATTTCGATAGTTGAGCAGGTAAAGCCAAAAGCTTTTCTAATGGAAAATGTTTCTGATATTGCCCAGGG
TGGAGAGCAGGAAATATTCAGATCAATAATTAATAGAGCTGAGAAAGCCGGTTATCGTATAGACCCCAAATTGATTTATG
CATGGCAGTATGGAGTCCCTCAACTCAGACCAAGATTATTTATTTCAGGAACAAAGATAAATGAATGTGCTCCAATGAAA
TGGCCAAAGCCAACATACAATTCCGTTGATAAAGCAGTTACATTGGAAGATGCGATTTCTGATTTACCTCCTTTGGAGGG
AGGATGGAACGAGAAGTGGGATGAGAGATATAGCTATGGAGGCCCCATAACCCCTTATCAAACATCTATGAGAGAATGGT
TAGAAATTGATGATGACGTAATTCATGATCACCTGATAAGAAAAGTTAGAGAGGATGATCTAGAAACATTTAAATTAATG
AGATCCACTGGAGTTAAATATTCTCAACTATCAGAAGCTCAAAGGAGATATTCAGTAACCAGCAGAGCTTTTAGGGAAGG
CAAGAAAGTAAAGGAAAATCAAAAGAATAGCTTTGGTGATAAATATAATATTCTCAAACCAAATGAACCATGTCTCACAA
TCACTGCTCATATGTCAAAAGATGGATACTGGTATATCCATCCCCAACAAAATAGAACACTCTCAGTCAGAGAAGCAGCA
AGAGTTCAATCATTTCCGGATGGGTTTAATTTTCATGGAGGACCTTCTAATAGATTCCATCAAATTGGAGAAGCAGTTGC
ACCCATAGTTGCTTATGAACTAGGAAAAGCATTAATTAAATCGATAAAAAATAAAAAAGATTATATGCAGGCAGATTTAG
TTCCTCAACTACGAAAAAATCTTATTAGCTGGTATGAATTAAATAAAAAAGAAGTTGAACTTATCTGGACAAAAAAAAGA
GAAGGTAGAAAAATTATTCCAAATGAAGTAAGAGCATGGAATGCATGCCTTGGAATCTTACTCCCAGAAACCTTCAAAAA
GGATCATAAGGATAAAAAGAAAAAAAATGTAGGAGAAAGTGATAAAAACCTGGAAGGTAGAAAAAAGGAAACATATAGAC
AGCTGAAAAAGTCCTGGCCTAATCCCGAAAGTTTTCTTCATGACAATATAAAAATGCGGACGATGAAAATAAAAAGTTTC
AGTCTTGAAAAATATATTCCTTCCCTAGAACTCTTAGCTGAAGATTTAAACAAAGATGAAATTGACTGGAGTGAAATAGC
CAGAAAAGATTATGGTTTATTTTCTAGGAATTCAGTAAGAGGAGCTCTTGCAACAGTTGGTCTGACCACTGAGATAAAAC
AATCCTTAGTAATAACAAAAATTATTTCTAAGTTGATGGATTTAGATTATGAGAAATTGAAATTCAGCAACATGAACAGA
GAGATACATATAGGTCATTTATTAGAGAAAGACAGTGAAGGTACTGGTTATTGCTCCTTACTGGCTTTATCTAAACAAGA
AGATACAGATGAAATTATCCAGAATAAATTAAAATTATTACCAAAAGAGCAAAAGATAGAAGCTGCCTGA

Upstream 100 bases:

>100_bases
CGATAAGAAAACTTAATTCTCTGGGTGGCTCTATATGTCTTGATCTATTGAGTGAAGAACAACTGCAAAAATTAATTGAT
ATTCAGGATAAGGAGGCTTC

Downstream 100 bases:

>100_bases
TAATTTACTGCCCGTACATATTACATATGTACGCTCTAAATGAATTTCTTGACAAATATAATTGACCTATATATAGTACA
TAGTAAGTTTATCTGGTGTC

Product: DNA-cytosine methyltransferase

Products: NA

Alternate protein names: M.XorII; Cytosine-specific methyltransferase XorII [H]

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MIHKNAVGKIDPHRLTPVRGPSTELDPHIDSCEFDELPGYAAKVRSLKKDPNFAVDLFSGAGGLSLGLHRANFDVILACD
IRNDSIMTHRHHFGGCSYECDLSKRKVVNEIADKLNECGEISLIAGGPPCQPFSRNIKWRKHNEEVSAQHQELNEDRREL
WESFISIVEQVKPKAFLMENVSDIAQGGEQEIFRSIINRAEKAGYRIDPKLIYAWQYGVPQLRPRLFISGTKINECAPMK
WPKPTYNSVDKAVTLEDAISDLPPLEGGWNEKWDERYSYGGPITPYQTSMREWLEIDDDVIHDHLIRKVREDDLETFKLM
RSTGVKYSQLSEAQRRYSVTSRAFREGKKVKENQKNSFGDKYNILKPNEPCLTITAHMSKDGYWYIHPQQNRTLSVREAA
RVQSFPDGFNFHGGPSNRFHQIGEAVAPIVAYELGKALIKSIKNKKDYMQADLVPQLRKNLISWYELNKKEVELIWTKKR
EGRKIIPNEVRAWNACLGILLPETFKKDHKDKKKKNVGESDKNLEGRKKETYRQLKKSWPNPESFLHDNIKMRTMKIKSF
SLEKYIPSLELLAEDLNKDEIDWSEIARKDYGLFSRNSVRGALATVGLTTEIKQSLVITKIISKLMDLDYEKLKFSNMNR
EIHIGHLLEKDSEGTGYCSLLALSKQEDTDEIIQNKLKLLPKEQKIEAA

Sequences:

>Translated_689_residues
MIHKNAVGKIDPHRLTPVRGPSTELDPHIDSCEFDELPGYAAKVRSLKKDPNFAVDLFSGAGGLSLGLHRANFDVILACD
IRNDSIMTHRHHFGGCSYECDLSKRKVVNEIADKLNECGEISLIAGGPPCQPFSRNIKWRKHNEEVSAQHQELNEDRREL
WESFISIVEQVKPKAFLMENVSDIAQGGEQEIFRSIINRAEKAGYRIDPKLIYAWQYGVPQLRPRLFISGTKINECAPMK
WPKPTYNSVDKAVTLEDAISDLPPLEGGWNEKWDERYSYGGPITPYQTSMREWLEIDDDVIHDHLIRKVREDDLETFKLM
RSTGVKYSQLSEAQRRYSVTSRAFREGKKVKENQKNSFGDKYNILKPNEPCLTITAHMSKDGYWYIHPQQNRTLSVREAA
RVQSFPDGFNFHGGPSNRFHQIGEAVAPIVAYELGKALIKSIKNKKDYMQADLVPQLRKNLISWYELNKKEVELIWTKKR
EGRKIIPNEVRAWNACLGILLPETFKKDHKDKKKKNVGESDKNLEGRKKETYRQLKKSWPNPESFLHDNIKMRTMKIKSF
SLEKYIPSLELLAEDLNKDEIDWSEIARKDYGLFSRNSVRGALATVGLTTEIKQSLVITKIISKLMDLDYEKLKFSNMNR
EIHIGHLLEKDSEGTGYCSLLALSKQEDTDEIIQNKLKLLPKEQKIEAA
>Mature_689_residues
MIHKNAVGKIDPHRLTPVRGPSTELDPHIDSCEFDELPGYAAKVRSLKKDPNFAVDLFSGAGGLSLGLHRANFDVILACD
IRNDSIMTHRHHFGGCSYECDLSKRKVVNEIADKLNECGEISLIAGGPPCQPFSRNIKWRKHNEEVSAQHQELNEDRREL
WESFISIVEQVKPKAFLMENVSDIAQGGEQEIFRSIINRAEKAGYRIDPKLIYAWQYGVPQLRPRLFISGTKINECAPMK
WPKPTYNSVDKAVTLEDAISDLPPLEGGWNEKWDERYSYGGPITPYQTSMREWLEIDDDVIHDHLIRKVREDDLETFKLM
RSTGVKYSQLSEAQRRYSVTSRAFREGKKVKENQKNSFGDKYNILKPNEPCLTITAHMSKDGYWYIHPQQNRTLSVREAA
RVQSFPDGFNFHGGPSNRFHQIGEAVAPIVAYELGKALIKSIKNKKDYMQADLVPQLRKNLISWYELNKKEVELIWTKKR
EGRKIIPNEVRAWNACLGILLPETFKKDHKDKKKKNVGESDKNLEGRKKETYRQLKKSWPNPESFLHDNIKMRTMKIKSF
SLEKYIPSLELLAEDLNKDEIDWSEIARKDYGLFSRNSVRGALATVGLTTEIKQSLVITKIISKLMDLDYEKLKFSNMNR
EIHIGHLLEKDSEGTGYCSLLALSKQEDTDEIIQNKLKLLPKEQKIEAA

Specific function: This methylase recognizes the double-stranded sequence CGATCG, causes specific methylation on C-? on both strands and protects the DNA from cleavage by the XorII endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4503351, Length=491, Percent_Identity=23.6252545824847, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI195927037, Length=491, Percent_Identity=23.6252545824847, Blast_Score=108, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 79230; Mature: 79230

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS00094 C5_MTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHKNAVGKIDPHRLTPVRGPSTELDPHIDSCEFDELPGYAAKVRSLKKDPNFAVDLFSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
AGGLSLGLHRANFDVILACDIRNDSIMTHRHHFGGCSYECDLSKRKVVNEIADKLNECGE
CCCCEEEEEECCCCEEEEEECCCCCEEEEHHHCCCCCEECCCHHHHHHHHHHHHHHCCCC
ISLIAGGPPCQPFSRNIKWRKHNEEVSAQHQELNEDRRELWESFISIVEQVKPKAFLMEN
EEEEECCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VSDIAQGGEQEIFRSIINRAEKAGYRIDPKLIYAWQYGVPQLRPRLFISGTKINECAPMK
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCC
WPKPTYNSVDKAVTLEDAISDLPPLEGGWNEKWDERYSYGGPITPYQTSMREWLEIDDDV
CCCCCCCCHHHHEEHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCHHH
IHDHLIRKVREDDLETFKLMRSTGVKYSQLSEAQRRYSVTSRAFREGKKVKENQKNSFGD
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCC
KYNILKPNEPCLTITAHMSKDGYWYIHPQQNRTLSVREAARVQSFPDGFNFHGGPSNRFH
CCCCCCCCCCEEEEEEEECCCCEEEEECCCCCEEHHHHHHHHHCCCCCCCCCCCCCHHHH
QIGEAVAPIVAYELGKALIKSIKNKKDYMQADLVPQLRKNLISWYELNKKEVELIWTKKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
EGRKIIPNEVRAWNACLGILLPETFKKDHKDKKKKNVGESDKNLEGRKKETYRQLKKSWP
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
NPESFLHDNIKMRTMKIKSFSLEKYIPSLELLAEDLNKDEIDWSEIARKDYGLFSRNSVR
CHHHHHHCCCEEEEEEEHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCC
GALATVGLTTEIKQSLVITKIISKLMDLDYEKLKFSNMNREIHIGHLLEKDSEGTGYCSL
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEHHHHCCCCCCCCEEEE
LALSKQEDTDEIIQNKLKLLPKEQKIEAA
EEECCCCCHHHHHHHHHHHCCCHHHCCCC
>Mature Secondary Structure
MIHKNAVGKIDPHRLTPVRGPSTELDPHIDSCEFDELPGYAAKVRSLKKDPNFAVDLFSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
AGGLSLGLHRANFDVILACDIRNDSIMTHRHHFGGCSYECDLSKRKVVNEIADKLNECGE
CCCCEEEEEECCCCEEEEEECCCCCEEEEHHHCCCCCEECCCHHHHHHHHHHHHHHCCCC
ISLIAGGPPCQPFSRNIKWRKHNEEVSAQHQELNEDRRELWESFISIVEQVKPKAFLMEN
EEEEECCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VSDIAQGGEQEIFRSIINRAEKAGYRIDPKLIYAWQYGVPQLRPRLFISGTKINECAPMK
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCC
WPKPTYNSVDKAVTLEDAISDLPPLEGGWNEKWDERYSYGGPITPYQTSMREWLEIDDDV
CCCCCCCCHHHHEEHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCHHH
IHDHLIRKVREDDLETFKLMRSTGVKYSQLSEAQRRYSVTSRAFREGKKVKENQKNSFGD
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCC
KYNILKPNEPCLTITAHMSKDGYWYIHPQQNRTLSVREAARVQSFPDGFNFHGGPSNRFH
CCCCCCCCCCEEEEEEEECCCCEEEEECCCCCEEHHHHHHHHHCCCCCCCCCCCCCHHHH
QIGEAVAPIVAYELGKALIKSIKNKKDYMQADLVPQLRKNLISWYELNKKEVELIWTKKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
EGRKIIPNEVRAWNACLGILLPETFKKDHKDKKKKNVGESDKNLEGRKKETYRQLKKSWP
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
NPESFLHDNIKMRTMKIKSFSLEKYIPSLELLAEDLNKDEIDWSEIARKDYGLFSRNSVR
CHHHHHHCCCEEEEEEEHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCC
GALATVGLTTEIKQSLVITKIISKLMDLDYEKLKFSNMNREIHIGHLLEKDSEGTGYCSL
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEHHHHCCCCCCCCEEEE
LALSKQEDTDEIIQNKLKLLPKEQKIEAA
EEECCCCCHHHHHHHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8078464 [H]