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The map label for this gene is cry2 [H]

Identifier: 123965634

GI number: 123965634

Start: 361515

End: 363026

Strand: Reverse

Name: cry2 [H]

Synonym: P9515_03991

Alternate gene names: 123965634

Gene position: 363026-361515 (Counterclockwise)

Preceding gene: 123965635

Following gene: 123965633

Centisome position: 21.3

GC content: 28.84

Gene sequence:

>1512_bases
ATGAAAAATATTAATATTTTATGGTTTAAAAAAGACTTAAGAATAAACGATAATGAGGCTCTTATCGAATCTCTAAAGGA
TAGAGACATTATACCTATATTCATAATTGAAAAAGAAATATGGAGTCAAAAAACTTATTCAGATAGACAATGGCAATTTT
GCAAGGAAAGTCTTTTAGACTTAAGAATTTCACTTGCAAATATTGGTCAACCTTTAATAATTAGAACGGGTAAAGTAATT
GAGATTTTTGATCAAATATCTAATAATTTTGAAATTAAAGCTATTTATAGCCATCAAGAAACTGGAGACTATTTGACATA
TAAAAGAGATCAAGAAGTTAGAAAATGGGCCTCTATGAAAAAAATTATTTGGAAAGAATATTTACAATTTTCAGTATTTA
GAGGAAAGCTAGATAGAAATAATTGGTCAACAAAATGGAAAAAAAATATGGAGAGAAAACTATTTACTGAACCTTCAAAA
ATTAATCCTATAGAAATTGATCCTGGAGAAATCCCACCAGATAATTTCTTTTGCTTCAAAGATGATTTCTGCAAAGGGAG
ATTAAAGGGTGGAAGAGAAATTGGTCTAAAGAGAATGGAATATTTTTTCAGTAATAAATTAAGTTATTACTCAAAAGATA
TTTCAAGCCCAGAGAAATCATTCGATAGCTGTTCAAGATTATCTCCCTATATAAGTTGGGGATGTATTTCTATAAAAGAG
ATTATTCATAAAGCAAATTCAATAACAAATCCCAATTCTAAAATGTTAAAAAGCAGATTAACTTGGCATTGTCACTTTAT
ACAAAAACTTGAGAGTGAACCAGAATTAGAGTTTAAAGAATTTCATCCTTATTTCCAAAAAATCAGAAAAAAAGATAGTC
ATTTACTCAAATTATGGAGTGAAGGTAAAACCGGTTTTCCTTTTTTAGATGCTTGTATGAGATCTTTAAATTTTCATGGA
TGGCTTAATTTCAGAATGCGTGCAATGCTAATGTCTTTTGCAAGTTATAATTTATGGATACCTTGGCAAGAATCCGGTTC
TGAATTGGCAAGCAAATTTCTCGATTATGAGCCAGGAATTCACTGGAATCAGTGTCAAATGCAAGCAGGTACAACATCTA
TAAATGTAAATAGAATATATAATCCTATTAAGCAGGGGAAAGATCATGATCCCAAAGGAAATTTTATTAAGAAATGGGTT
CCTGAGATACAAAATTATCCTGAAAATTTCGTCCATGAACCTTGGTTGATGGAAAAATTTAATTCCAAAGAATATGAAAA
CTCTGAATACATTAAACCAATAATTAACCTCTCAGAAACAACTAAAAATGCACGAAAAAGAATTCAAGAAATAACCCAAA
GAGAAGGTTACTGGGATATTTCAAAAGGAATTTATATGAAACATGGCTCAAGAAGAAAAGCTCTAAATAAGAGAAAAAAT
TATCCTAAAAAGAGTAATTTGAGAAAAAAAAGAGAACTTCAAAATCAATTAAATCTTGATTTACTAATTTAA

Upstream 100 bases:

>100_bases
TGGATAATAAAGATTTTTTAAAATTATTCCAAAAAGATTAAATTTCGTATTTAGTTACTAATTAATAATTAATTTTTTAT
AATGAGAAAAAACTTTTTTG

Downstream 100 bases:

>100_bases
TTAATTTGAAAATAAATTAAAACTTTAAAGGCAAAACAAACTTTGATTTTTTTTAATAGAAAAAATTTTATATTTTATAA
AAATGATTCAAGTTAAATAA

Product: putative deoxyribodipyrimidine photolyase

Products: 2 pyrimidine residues (in DNA) [C]

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MKNINILWFKKDLRINDNEALIESLKDRDIIPIFIIEKEIWSQKTYSDRQWQFCKESLLDLRISLANIGQPLIIRTGKVI
EIFDQISNNFEIKAIYSHQETGDYLTYKRDQEVRKWASMKKIIWKEYLQFSVFRGKLDRNNWSTKWKKNMERKLFTEPSK
INPIEIDPGEIPPDNFFCFKDDFCKGRLKGGREIGLKRMEYFFSNKLSYYSKDISSPEKSFDSCSRLSPYISWGCISIKE
IIHKANSITNPNSKMLKSRLTWHCHFIQKLESEPELEFKEFHPYFQKIRKKDSHLLKLWSEGKTGFPFLDACMRSLNFHG
WLNFRMRAMLMSFASYNLWIPWQESGSELASKFLDYEPGIHWNQCQMQAGTTSINVNRIYNPIKQGKDHDPKGNFIKKWV
PEIQNYPENFVHEPWLMEKFNSKEYENSEYIKPIINLSETTKNARKRIQEITQREGYWDISKGIYMKHGSRRKALNKRKN
YPKKSNLRKKRELQNQLNLDLLI

Sequences:

>Translated_503_residues
MKNINILWFKKDLRINDNEALIESLKDRDIIPIFIIEKEIWSQKTYSDRQWQFCKESLLDLRISLANIGQPLIIRTGKVI
EIFDQISNNFEIKAIYSHQETGDYLTYKRDQEVRKWASMKKIIWKEYLQFSVFRGKLDRNNWSTKWKKNMERKLFTEPSK
INPIEIDPGEIPPDNFFCFKDDFCKGRLKGGREIGLKRMEYFFSNKLSYYSKDISSPEKSFDSCSRLSPYISWGCISIKE
IIHKANSITNPNSKMLKSRLTWHCHFIQKLESEPELEFKEFHPYFQKIRKKDSHLLKLWSEGKTGFPFLDACMRSLNFHG
WLNFRMRAMLMSFASYNLWIPWQESGSELASKFLDYEPGIHWNQCQMQAGTTSINVNRIYNPIKQGKDHDPKGNFIKKWV
PEIQNYPENFVHEPWLMEKFNSKEYENSEYIKPIINLSETTKNARKRIQEITQREGYWDISKGIYMKHGSRRKALNKRKN
YPKKSNLRKKRELQNQLNLDLLI
>Mature_503_residues
MKNINILWFKKDLRINDNEALIESLKDRDIIPIFIIEKEIWSQKTYSDRQWQFCKESLLDLRISLANIGQPLIIRTGKVI
EIFDQISNNFEIKAIYSHQETGDYLTYKRDQEVRKWASMKKIIWKEYLQFSVFRGKLDRNNWSTKWKKNMERKLFTEPSK
INPIEIDPGEIPPDNFFCFKDDFCKGRLKGGREIGLKRMEYFFSNKLSYYSKDISSPEKSFDSCSRLSPYISWGCISIKE
IIHKANSITNPNSKMLKSRLTWHCHFIQKLESEPELEFKEFHPYFQKIRKKDSHLLKLWSEGKTGFPFLDACMRSLNFHG
WLNFRMRAMLMSFASYNLWIPWQESGSELASKFLDYEPGIHWNQCQMQAGTTSINVNRIYNPIKQGKDHDPKGNFIKKWV
PEIQNYPENFVHEPWLMEKFNSKEYENSEYIKPIINLSETTKNARKRIQEITQREGYWDISKGIYMKHGSRRKALNKRKN
YPKKSNLRKKRELQNQLNLDLLI

Specific function: Has no photolyase activity [H]

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Homo sapiens, GI4758072, Length=493, Percent_Identity=23.1237322515213, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI188536100, Length=492, Percent_Identity=21.3414634146341, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI188536103, Length=285, Percent_Identity=24.2105263157895, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1786926, Length=484, Percent_Identity=23.9669421487603, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6324962, Length=483, Percent_Identity=25.6728778467909, Blast_Score=83, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17137248, Length=462, Percent_Identity=23.8095238095238, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24585455, Length=462, Percent_Identity=23.8095238095238, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24648152, Length=501, Percent_Identity=23.1536926147705, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: 4.1.99.3 [C]

Molecular weight: Translated: 60183; Mature: 60183

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNINILWFKKDLRINDNEALIESLKDRDIIPIFIIEKEIWSQKTYSDRQWQFCKESLLD
CCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHH
LRISLANIGQPLIIRTGKVIEIFDQISNNFEIKAIYSHQETGDYLTYKRDQEVRKWASMK
HHHHHHHCCCCEEEECCHHHHHHHHHCCCEEEEEEECCCCCCCCEEECCHHHHHHHHHHH
KIIWKEYLQFSVFRGKLDRNNWSTKWKKNMERKLFTEPSKINPIEIDPGEIPPDNFFCFK
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCEEEEC
DDFCKGRLKGGREIGLKRMEYFFSNKLSYYSKDISSPEKSFDSCSRLSPYISWGCISIKE
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHH
IIHKANSITNPNSKMLKSRLTWHCHFIQKLESEPELEFKEFHPYFQKIRKKDSHLLKLWS
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EGKTGFPFLDACMRSLNFHGWLNFRMRAMLMSFASYNLWIPWQESGSELASKFLDYEPGI
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHCCCCCC
HWNQCQMQAGTTSINVNRIYNPIKQGKDHDPKGNFIKKWVPEIQNYPENFVHEPWLMEKF
CCCCEEEECCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCHHHHHC
NSKEYENSEYIKPIINLSETTKNARKRIQEITQREGYWDISKGIYMKHGSRRKALNKRKN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEECCCCHHHHHHHHHC
YPKKSNLRKKRELQNQLNLDLLI
CCCHHHHHHHHHHHHHCCCEEEC
>Mature Secondary Structure
MKNINILWFKKDLRINDNEALIESLKDRDIIPIFIIEKEIWSQKTYSDRQWQFCKESLLD
CCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHH
LRISLANIGQPLIIRTGKVIEIFDQISNNFEIKAIYSHQETGDYLTYKRDQEVRKWASMK
HHHHHHHCCCCEEEECCHHHHHHHHHCCCEEEEEEECCCCCCCCEEECCHHHHHHHHHHH
KIIWKEYLQFSVFRGKLDRNNWSTKWKKNMERKLFTEPSKINPIEIDPGEIPPDNFFCFK
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCEEEEC
DDFCKGRLKGGREIGLKRMEYFFSNKLSYYSKDISSPEKSFDSCSRLSPYISWGCISIKE
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHH
IIHKANSITNPNSKMLKSRLTWHCHFIQKLESEPELEFKEFHPYFQKIRKKDSHLLKLWS
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EGKTGFPFLDACMRSLNFHGWLNFRMRAMLMSFASYNLWIPWQESGSELASKFLDYEPGI
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHCCCCCC
HWNQCQMQAGTTSINVNRIYNPIKQGKDHDPKGNFIKKWVPEIQNYPENFVHEPWLMEKF
CCCCEEEECCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCHHHHHC
NSKEYENSEYIKPIINLSETTKNARKRIQEITQREGYWDISKGIYMKHGSRRKALNKRKN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEECCCCHHHHHHHHHC
YPKKSNLRKKRELQNQLNLDLLI
CCCHHHHHHHHHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: ATP; FADH2; Flavin; pterin [C]

Metal ions: NA

Kcat value (1/min): 2.4 [C]

Specific activity: NA

Km value (mM): NA

Substrates: cyclobutadipyrimidine (in DNA) [C]

Specific reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA) [C]

General reaction: C-C-bond cleavage [C]

Inhibitor: yeast DNA [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]