Click here to switch to the map view.

The map label for this gene is pip [H]

Identifier: 123965631

GI number: 123965631

Start: 359937

End: 360878

Strand: Direct

Name: pip [H]

Synonym: P9515_03961

Alternate gene names: 123965631

Gene position: 359937-360878 (Clockwise)

Preceding gene: 123965630

Following gene: 123965637

Centisome position: 21.12

GC content: 30.79

Gene sequence:

>942_bases
ATGAAAGAAAAAAAATTATTCCCCATAATAGAACCAAGAGAAAAGGGTTTTTTGCAAGTAAGTAGAATTCATTCTATCTA
TTGGGAAAGATCAGGAAATCAAAATGGTAAAAAGATACTAGTAATTCATGGCGGTCCTGGTGGAGGAAGTCAGCCAAGAT
ATAGAAGATATTTTAATCCTGAGAAATTTGATATTATTCAATTTGATCAAAGAGGTTGCGGTGCCTCAAGACCTTTTTCA
GAATTAAGAGAAAATACAACAAAAGATCTAGTAGATGATATTGAAAAATTAAGATTAAATCTTAATATAGATTCTTGGCA
TTTGTTTGGAGGATCATGGGGATCTACGTTAGCTTTGATTTATGCAATAAAACATCCATCTAGGGTCAAAAGTATGACCT
TAAGAGGAATATTTTTATGTAGAAAATTTGAACTCTCATGGTTCTACCAATATGGTGCAAGTGAAATTTTCCCAGAAGAG
TTTGAAAAATATATCTCAGTTATTCCTAAAGATGAAAGGTCTGATTTGGTATCTTCTTTTTATAAATATTTAACATCTCC
TAATATCGAACTTAGATCAAAAGCTGCGGCTGCGTGGACAACTTGGGAACTTTCTACAAGTCATCTTATTAAGAGAGATA
TTGATGTTGGTAAAAGTAAAACTAATTCCTTTTCAGATGCTTTCGCAAGAATAGAATGTCATTATTTCATAAACCATATC
TTCTTAGAGGAGGATTTTATTATGAAAAATATAAAGACTATAGAATCTATTCCAACTAAAATCATTCAAGGAAGATATGA
CGTGGTCTGTCCTGTGAGAAGTGCTTGGGATCTAAATAAAAAATTAAAAAATTCAGAATTAATAATCATTGATGAAGCTG
GTCATTCTATGAGTGAAAAGGGAATCACATTGAAATTATTAGAATTAGTTGAAAAGTTATAA

Upstream 100 bases:

>100_bases
GCTTTTTATTAAAGGCCTCTTTTTTCATGATTTATAAAATTACAAACACTTTAGTGTAGATAATATTAATTTTCTATTTG
AAATAATTTATATTTATGGA

Downstream 100 bases:

>100_bases
AATTTTTGGTAAAACTTTATTTAATATGATTTCATCAATATTTAGAGACCATTATCTTCAATATTTTTAGCAATACTTCT
TAGTAATTCAACAATATCAG

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKEKKLFPIIEPREKGFLQVSRIHSIYWERSGNQNGKKILVIHGGPGGGSQPRYRRYFNPEKFDIIQFDQRGCGASRPFS
ELRENTTKDLVDDIEKLRLNLNIDSWHLFGGSWGSTLALIYAIKHPSRVKSMTLRGIFLCRKFELSWFYQYGASEIFPEE
FEKYISVIPKDERSDLVSSFYKYLTSPNIELRSKAAAAWTTWELSTSHLIKRDIDVGKSKTNSFSDAFARIECHYFINHI
FLEEDFIMKNIKTIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIIDEAGHSMSEKGITLKLLELVEKL

Sequences:

>Translated_313_residues
MKEKKLFPIIEPREKGFLQVSRIHSIYWERSGNQNGKKILVIHGGPGGGSQPRYRRYFNPEKFDIIQFDQRGCGASRPFS
ELRENTTKDLVDDIEKLRLNLNIDSWHLFGGSWGSTLALIYAIKHPSRVKSMTLRGIFLCRKFELSWFYQYGASEIFPEE
FEKYISVIPKDERSDLVSSFYKYLTSPNIELRSKAAAAWTTWELSTSHLIKRDIDVGKSKTNSFSDAFARIECHYFINHI
FLEEDFIMKNIKTIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIIDEAGHSMSEKGITLKLLELVEKL
>Mature_313_residues
MKEKKLFPIIEPREKGFLQVSRIHSIYWERSGNQNGKKILVIHGGPGGGSQPRYRRYFNPEKFDIIQFDQRGCGASRPFS
ELRENTTKDLVDDIEKLRLNLNIDSWHLFGGSWGSTLALIYAIKHPSRVKSMTLRGIFLCRKFELSWFYQYGASEIFPEE
FEKYISVIPKDERSDLVSSFYKYLTSPNIELRSKAAAAWTTWELSTSHLIKRDIDVGKSKTNSFSDAFARIECHYFINHI
FLEEDFIMKNIKTIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIIDEAGHSMSEKGITLKLLELVEKL

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36298; Mature: 36298

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKKLFPIIEPREKGFLQVSRIHSIYWERSGNQNGKKILVIHGGPGGGSQPRYRRYFNP
CCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHCCCC
EKFDIIQFDQRGCGASRPFSELRENTTKDLVDDIEKLRLNLNIDSWHLFGGSWGSTLALI
CCEEEEEECCCCCCCCCCHHHHHHCHHHHHHHHHHHHEEECCCCEEEEECCCCHHHEEEE
YAIKHPSRVKSMTLRGIFLCRKFELSWFYQYGASEIFPEEFEKYISVIPKDERSDLVSSF
EEECCCHHHHHHHHHHEEEEEEECHHHHEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
YKYLTSPNIELRSKAAAAWTTWELSTSHLIKRDIDVGKSKTNSFSDAFARIECHYFINHI
HHHHCCCCCEECCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
FLEEDFIMKNIKTIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIIDEAGHSMSEK
HCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCEEEEECCCCCCCCC
GITLKLLELVEKL
CCCHHHHHHHHCC
>Mature Secondary Structure
MKEKKLFPIIEPREKGFLQVSRIHSIYWERSGNQNGKKILVIHGGPGGGSQPRYRRYFNP
CCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHCCCC
EKFDIIQFDQRGCGASRPFSELRENTTKDLVDDIEKLRLNLNIDSWHLFGGSWGSTLALI
CCEEEEEECCCCCCCCCCHHHHHHCHHHHHHHHHHHHEEECCCCEEEEECCCCHHHEEEE
YAIKHPSRVKSMTLRGIFLCRKFELSWFYQYGASEIFPEEFEKYISVIPKDERSDLVSSF
EEECCCHHHHHHHHHHEEEEEEECHHHHEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
YKYLTSPNIELRSKAAAAWTTWELSTSHLIKRDIDVGKSKTNSFSDAFARIECHYFINHI
HHHHCCCCCEECCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
FLEEDFIMKNIKTIESIPTKIIQGRYDVVCPVRSAWDLNKKLKNSELIIIDEAGHSMSEK
HCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCEEEEECCCCCCCCC
GITLKLLELVEKL
CCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA