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The map label for this gene is nrdR

Identifier: 123965581

GI number: 123965581

Start: 319725

End: 320204

Strand: Reverse

Name: nrdR

Synonym: P9515_03461

Alternate gene names: 123965581

Gene position: 320204-319725 (Counterclockwise)

Preceding gene: 123965582

Following gene: 123965580

Centisome position: 18.79

GC content: 32.29

Gene sequence:

>480_bases
ATGCAGTGTCCGACCTGTCAAAATACAGATAGCAGAGTTTTAGAATCAAGATCTGCTGATACAGGAAAAAGTGTAAGAAG
AAGAAGAGAGTGTTTAAATTGCAGCTTTAGATTTACTACTTATGAAAGAGTTGAGACGATGCCAATTTCTGTCCTGAAAA
AGGACGGGAGCAGAGAATTATTTAATAAAGATAAATTAGTTACTGGGATTTCTAGAGCATGCGAAAAAACAACATTTTCT
AGAGAAGCGATTATTGATTTTGTTGACTCTATTGAATCGCAAATAATACAAGACTCAAATAAAGATATTAAATCCTCTCA
AATTGGAGAATTAATTCTTAAAGGCTTAAGGAAAGAAAACGAAGTTGCTTACATAAGATACGCATCAGTATATAGGAAGT
TTAATGGGGTAAAAGACTTTGTTTCAACTCTCGAATCTCTAAAAGGCAGTTCAAAAAATGAATTAGCTTCAATTTTATAA

Upstream 100 bases:

>100_bases
GTAAAAAACCCTCCATAATTTAGGAGGGTTTTTTTTTACTACTTTTCATAATCGTGATATTAATCTACTATTAGAGGTAA
AGATTGTATTAATTCACTAT

Downstream 100 bases:

>100_bases
ATTAAGCATATTAAAGTGTAGAATATTAAATACAATAAATTGCTCTTTAGTTTGCAGGCTAAAAGTAATCCTATCTAACT
ACCCCAGGTAGTCTGCGTTT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MQCPTCQNTDSRVLESRSADTGKSVRRRRECLNCSFRFTTYERVETMPISVLKKDGSRELFNKDKLVTGISRACEKTTFS
REAIIDFVDSIESQIIQDSNKDIKSSQIGELILKGLRKENEVAYIRYASVYRKFNGVKDFVSTLESLKGSSKNELASIL

Sequences:

>Translated_159_residues
MQCPTCQNTDSRVLESRSADTGKSVRRRRECLNCSFRFTTYERVETMPISVLKKDGSRELFNKDKLVTGISRACEKTTFS
REAIIDFVDSIESQIIQDSNKDIKSSQIGELILKGLRKENEVAYIRYASVYRKFNGVKDFVSTLESLKGSSKNELASIL
>Mature_159_residues
MQCPTCQNTDSRVLESRSADTGKSVRRRRECLNCSFRFTTYERVETMPISVLKKDGSRELFNKDKLVTGISRACEKTTFS
REAIIDFVDSIESQIIQDSNKDIKSSQIGELILKGLRKENEVAYIRYASVYRKFNGVKDFVSTLESLKGSSKNELASIL

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=140, Percent_Identity=42.8571428571429, Blast_Score=121, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_PROM5 (A2BUU4)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001010662.1
- STRING:   A2BUU4
- GeneID:   4718705
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_03461
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   PMAR167542:P9515ORF_0362-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18094; Mature: 18094

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCPTCQNTDSRVLESRSADTGKSVRRRRECLNCSFRFTTYERVETMPISVLKKDGSREL
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHH
FNKDKLVTGISRACEKTTFSREAIIDFVDSIESQIIQDSNKDIKSSQIGELILKGLRKEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
EVAYIRYASVYRKFNGVKDFVSTLESLKGSSKNELASIL
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MQCPTCQNTDSRVLESRSADTGKSVRRRRECLNCSFRFTTYERVETMPISVLKKDGSREL
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHH
FNKDKLVTGISRACEKTTFSREAIIDFVDSIESQIIQDSNKDIKSSQIGELILKGLRKEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
EVAYIRYASVYRKFNGVKDFVSTLESLKGSSKNELASIL
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA