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The map label for this gene is sms [H]

Identifier: 123965396

GI number: 123965396

Start: 148021

End: 149373

Strand: Reverse

Name: sms [H]

Synonym: P9515_01611

Alternate gene names: 123965396

Gene position: 149373-148021 (Counterclockwise)

Preceding gene: 123965402

Following gene: 123965394

Centisome position: 8.77

GC content: 32.82

Gene sequence:

>1353_bases
ATGTCTAGTAAATTTTCGACTTTTATTTGTCAAAATTGCGGATCTGAAACTTCTCAATACTTTGGTAGGTGCGTAAATTG
TAATGAATGGAATACAATCGTTGAAGAAAGGAAAATTTCAAGATCCAAAACAACAAATATTACCAAAAGTAAAAAATCAA
AGCTATTTCATGAAATTGAACTAAATACAATATCAAGATTTACGAGTGGTTTTAAGGAATTTGACAGAGTTCTAGGGGGT
GGAATAGTACCAGGATCTTTAGTTTTACTTGGGGGAGAACCAGGAATTGGTAAAAGTACAATAGTGCTGCAATCTGCAGG
GATAATCTCTCTGAATGAAAAAGTTTTATACATCACCGCAGAGGAATCTTTAGAACAAGTAAAAATAAGATGGGAACGAT
TAAATCAAAGCAGCCTAGATTTAAAAATCTATGCAGAAACAAACTTATCTTTAATTATTGAAGAGATAAAAAAAATTAAG
CCTAGTTTTGCGATTATTGATAGTATCCAAGCTATTAATAATGATGAAATGGAAAGTTCCCCGGGCTCTGTTTCCCAGGT
TCGGGCTTGCTCATCTGAACTTCAAAACCTGGCAAAAGAAAATAATATAGCGCTCTTGATAATTGGTCATGTCACTAAAG
AGGGGGCTCTTGCAGGTCCAAAAACTTTAGAACATTTAGTAGATGTTGTTCTTAACTTTGAGGGAGATAATATTGCCTCA
CATAGATTACTCAGAAGTGTAAAAAATAGGTTTGGATCTACTTTTGAAATTGGAATTTTCGAAATGTTAGAAAATGGGTT
AAAAGAAGTTGGGAACCCTAGTTCAATTTTCACAAATAAAGAAAATATATCCGGCGTCACAACTACGATAACTAATGAGG
GATCTAGACCATTTGCAGTAGATATTCAAGCTTTGGTGAATAAAACTTTTTACACTAACCCAAGACGAACAACTACAGGA
ATCAGTATCAACAGACTACATCAAATATTAGCAGTCATTGAAAAACATGTTGGGATTAAATTATCAGATTATGACTGTTA
TATAGCAACAGGAGGCGGGTTTGAAATAAATGACCCATCTTCAGATTTGGGGGTTGCAATATCAATCTTATCAAGCTTGA
AAAATATTCCCCCCTTAATAAATTGTTCATTTGTAGGCGAATTAGGTTTAAGTGGTCAGGTAAGGCAGGCAAATAATCTT
CGAACCAAAATTGATGAAGCTATTAGACTTGGTTTCAAAAATATTTTGATACCTAAAACAACTTGTGAAATTAAAGATAA
TTTTCAAACTCTCATAAAGATTAAAGAAATTTCAAATATTAATGAAGCTATGAATTATGTTCTAAAAGAGTGA

Upstream 100 bases:

>100_bases
TCTATTAGCTAATCTGGAAGAGAATTTATGTTTAACCCAATCTAACTTGTAGAGGGGCATATTCCCAAACATCTCAGTTC
GTCAATCTAAAAAAAATTTA

Downstream 100 bases:

>100_bases
ATCAAAAAATCTAAAGATAAATATCAATTGAACTTCTTCCAGAAGTTTTTAACCAATTTTCAATATCTAAATATCCACCA
GGATAAAGCCTCACAGCTTT

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSSKFSTFICQNCGSETSQYFGRCVNCNEWNTIVEERKISRSKTTNITKSKKSKLFHEIELNTISRFTSGFKEFDRVLGG
GIVPGSLVLLGGEPGIGKSTIVLQSAGIISLNEKVLYITAEESLEQVKIRWERLNQSSLDLKIYAETNLSLIIEEIKKIK
PSFAIIDSIQAINNDEMESSPGSVSQVRACSSELQNLAKENNIALLIIGHVTKEGALAGPKTLEHLVDVVLNFEGDNIAS
HRLLRSVKNRFGSTFEIGIFEMLENGLKEVGNPSSIFTNKENISGVTTTITNEGSRPFAVDIQALVNKTFYTNPRRTTTG
ISINRLHQILAVIEKHVGIKLSDYDCYIATGGGFEINDPSSDLGVAISILSSLKNIPPLINCSFVGELGLSGQVRQANNL
RTKIDEAIRLGFKNILIPKTTCEIKDNFQTLIKIKEISNINEAMNYVLKE

Sequences:

>Translated_450_residues
MSSKFSTFICQNCGSETSQYFGRCVNCNEWNTIVEERKISRSKTTNITKSKKSKLFHEIELNTISRFTSGFKEFDRVLGG
GIVPGSLVLLGGEPGIGKSTIVLQSAGIISLNEKVLYITAEESLEQVKIRWERLNQSSLDLKIYAETNLSLIIEEIKKIK
PSFAIIDSIQAINNDEMESSPGSVSQVRACSSELQNLAKENNIALLIIGHVTKEGALAGPKTLEHLVDVVLNFEGDNIAS
HRLLRSVKNRFGSTFEIGIFEMLENGLKEVGNPSSIFTNKENISGVTTTITNEGSRPFAVDIQALVNKTFYTNPRRTTTG
ISINRLHQILAVIEKHVGIKLSDYDCYIATGGGFEINDPSSDLGVAISILSSLKNIPPLINCSFVGELGLSGQVRQANNL
RTKIDEAIRLGFKNILIPKTTCEIKDNFQTLIKIKEISNINEAMNYVLKE
>Mature_449_residues
SSKFSTFICQNCGSETSQYFGRCVNCNEWNTIVEERKISRSKTTNITKSKKSKLFHEIELNTISRFTSGFKEFDRVLGGG
IVPGSLVLLGGEPGIGKSTIVLQSAGIISLNEKVLYITAEESLEQVKIRWERLNQSSLDLKIYAETNLSLIIEEIKKIKP
SFAIIDSIQAINNDEMESSPGSVSQVRACSSELQNLAKENNIALLIIGHVTKEGALAGPKTLEHLVDVVLNFEGDNIASH
RLLRSVKNRFGSTFEIGIFEMLENGLKEVGNPSSIFTNKENISGVTTTITNEGSRPFAVDIQALVNKTFYTNPRRTTTGI
SINRLHQILAVIEKHVGIKLSDYDCYIATGGGFEINDPSSDLGVAISILSSLKNIPPLINCSFVGELGLSGQVRQANNLR
TKIDEAIRLGFKNILIPKTTCEIKDNFQTLIKIKEISNINEAMNYVLKE

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=426, Percent_Identity=40.3755868544601, Blast_Score=357, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49625; Mature: 49494

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKFSTFICQNCGSETSQYFGRCVNCNEWNTIVEERKISRSKTTNITKSKKSKLFHEIE
CCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LNTISRFTSGFKEFDRVLGGGIVPGSLVLLGGEPGIGKSTIVLQSAGIISLNEKVLYITA
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEEECCEEEECCEEEEEEC
EESLEQVKIRWERLNQSSLDLKIYAETNLSLIIEEIKKIKPSFAIIDSIQAINNDEMESS
HHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
PGSVSQVRACSSELQNLAKENNIALLIIGHVTKEGALAGPKTLEHLVDVVLNFEGDNIAS
CCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHH
HRLLRSVKNRFGSTFEIGIFEMLENGLKEVGNPSSIFTNKENISGVTTTITNEGSRPFAV
HHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCHHEECCCCCCCCEEEEEECCCCCCEEE
DIQALVNKTFYTNPRRTTTGISINRLHQILAVIEKHVGIKLSDYDCYIATGGGFEINDPS
EHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCEEEEEECCCEEECCCC
SDLGVAISILSSLKNIPPLINCSFVGELGLSGQVRQANNLRTKIDEAIRLGFKNILIPKT
CHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCHHHEECCCC
TCEIKDNFQTLIKIKEISNINEAMNYVLKE
EECHHHCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSKFSTFICQNCGSETSQYFGRCVNCNEWNTIVEERKISRSKTTNITKSKKSKLFHEIE
CCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LNTISRFTSGFKEFDRVLGGGIVPGSLVLLGGEPGIGKSTIVLQSAGIISLNEKVLYITA
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEEECCEEEECCEEEEEEC
EESLEQVKIRWERLNQSSLDLKIYAETNLSLIIEEIKKIKPSFAIIDSIQAINNDEMESS
HHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
PGSVSQVRACSSELQNLAKENNIALLIIGHVTKEGALAGPKTLEHLVDVVLNFEGDNIAS
CCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHH
HRLLRSVKNRFGSTFEIGIFEMLENGLKEVGNPSSIFTNKENISGVTTTITNEGSRPFAV
HHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCHHEECCCCCCCCEEEEEECCCCCCEEE
DIQALVNKTFYTNPRRTTTGISINRLHQILAVIEKHVGIKLSDYDCYIATGGGFEINDPS
EHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCEEEEEECCCEEECCCC
SDLGVAISILSSLKNIPPLINCSFVGELGLSGQVRQANNLRTKIDEAIRLGFKNILIPKT
CHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCHHHEECCCC
TCEIKDNFQTLIKIKEISNINEAMNYVLKE
EECHHHCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]