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The map label for this gene is speA

Identifier: 123965287

GI number: 123965287

Start: 56561

End: 58507

Strand: Reverse

Name: speA

Synonym: P9515_00521

Alternate gene names: 123965287

Gene position: 58507-56561 (Counterclockwise)

Preceding gene: 123965289

Following gene: 123965285

Centisome position: 3.43

GC content: 29.17

Gene sequence:

>1947_bases
TTGACAAATTTTGACTCAAAAAAATTAAATAAACATTGGACCATAGAAGATAGTATTTCTACATATGGTATTGATAAATG
GGGAGATCAGTATTTTTCAATAAATTCATTAGGCAATATATCGATAACCCCAAATAGAAACTCTAAAAAAACAATTGATC
TTTTTAAACTTGTTAATGAAATTAAAAGTAGAGAAATAAATACTCCTTTAATATTAAGATTTAACGACATTTTAAAAGAC
CGAATCACAGAATTAAATAATGCCTTCTCCCAAGCAATAGAAACTTATAACTATAAAAATATTTTTCAAGGAGTTTTTCC
TATCAAATGTAATCAGCAAAAAAATGTATTAGAAAAAATCATTGAATATGGAGATTATTGGGACTTTGGTTTAGAGGTAG
GAAGCAAGTCAGAATTATTAATTGGATTATCATTGCTAGAAAATAAAAAATCACTTTTAATTTGTAATGGATATAAAGAT
AAAAAGTATATTGAGATCGCAATACTAGCCAGAAAACTTGGTAAACAGCCAATTATAGTTATTGAGCAAATAGATGAAGT
TCAAAGAATTATTGAAGCTGTCAAAAATCTCAGATCAACACCTATACTTGGCATCAGATCAAAGTTATCAAGCAAAAGTA
GTGGGAGATGGGGTAAATCAGTTGGAGATAACTCCAAATTTGGATTATCAATTCCGGAAATAATGTTAACCATAAAAGAA
CTTAAAGAAGCAAGCTTAATTAATGAAATGAAGTTGCTGCATTTCCATATTGGAAGCCAAATAAGTGATATTTCAGTAAT
AAAAGACGCATTGCAAGAAGCGAGTCAAATATTTGTTGAATTATCTAAGTTAGGCGCACCAATGAAATATATAGATGTGG
GAGGCGGCTTAGGAATAGACTTCGATGGAACTAAAACGTCTTCCAATACTTCGACAAATTATTCTCTTCAAAACTATGCG
AATGATGTCGTAGCAACAATCAAAGATTCATGTGAAGTAAATAATATTCAACATCCAATCATAATCTCAGAAAGCGGGAG
AGCTATAGTAAGTCACTGTTCAGTTTTAATTTTTGATGTTTTAGGAACAAGTCATGTCAGCTCTCAAATAAAAGTATCAC
ACCAAAAAAAGACATCATTAATCATCAAAAATCTTATTGATACCCATAATCAACTTAAAAATCTTAGAAACAAAAAAGAA
GATTTATCTGAAATTATAGAATTATGGAACGACGCTAAAAAATTCAAAAAGGATTGCTTAGTCGCTTTTAGATTGGGATT
TATAAGTTTGGGGGAACGTGCTTATGCCGAAGAACTTACATGGGCATGTGCAAAAGAGATTTCAAGTCACTTAGATAATG
AAAAAATTATCCATCCAGACTTATCTGAGATAACCGAAACGCTTTCATCAACTTATTACGCTAATTTGTCAGTTTTCAAA
TCTATTCCGGATACTTGGGCAATTAATCAAATTTTTCCAATTATTCCAATACACAGACATTTAGAAGAACCCATATGTAA
AGGTAATTTTGCCGATTTAACTTGTGATTCTGATGGCAAACTAAATAATTTTATTGACAATGGGAAAATTAAATCACTTC
TAAATTTACATCGCCCAGAAGAGAACAATGATTATTTAATAGGAATCTTTATGGCAGGTGCATATCAAGAGGCATTAGGG
AATTTTCATAATCTATTTGGAAATACTAATGTTATTCATATTGATATAAATGAAGATAATACATATAAAATTAAAAATAT
TATTAAAGAAAACAGCAAATCAGAAATTTTAGAATTATTAGATTACAGTTCAGATAATTTAGTCGAATCAATAAGAATTA
ATACCGAATTTGCCATCAATAATAAAACCTTGAGTATTGAAGAAGCACGAAAATTAATTGATCAAATAGAGACGAGTTTA
AGAAAAAGTAGTTATTTATCAGAATAA

Upstream 100 bases:

>100_bases
GTATATTCTTCTTTTAGGTGCTAACTTGGCAAGTAATCATTAAAATAATAGATATTGTCTTGATTAATTTTCAAAACTTT
TATAACTCACAGAGACAGAT

Downstream 100 bases:

>100_bases
CTTAGTAACTTTTCCCACAAGTCTTTTCTTGCATATTCCAACGCATCATTTAATTTATCAATATCTTTGGCACCTGCCTG
CGCAAAGTTAGGTTTCCCTC

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MTNFDSKKLNKHWTIEDSISTYGIDKWGDQYFSINSLGNISITPNRNSKKTIDLFKLVNEIKSREINTPLILRFNDILKD
RITELNNAFSQAIETYNYKNIFQGVFPIKCNQQKNVLEKIIEYGDYWDFGLEVGSKSELLIGLSLLENKKSLLICNGYKD
KKYIEIAILARKLGKQPIIVIEQIDEVQRIIEAVKNLRSTPILGIRSKLSSKSSGRWGKSVGDNSKFGLSIPEIMLTIKE
LKEASLINEMKLLHFHIGSQISDISVIKDALQEASQIFVELSKLGAPMKYIDVGGGLGIDFDGTKTSSNTSTNYSLQNYA
NDVVATIKDSCEVNNIQHPIIISESGRAIVSHCSVLIFDVLGTSHVSSQIKVSHQKKTSLIIKNLIDTHNQLKNLRNKKE
DLSEIIELWNDAKKFKKDCLVAFRLGFISLGERAYAEELTWACAKEISSHLDNEKIIHPDLSEITETLSSTYYANLSVFK
SIPDTWAINQIFPIIPIHRHLEEPICKGNFADLTCDSDGKLNNFIDNGKIKSLLNLHRPEENNDYLIGIFMAGAYQEALG
NFHNLFGNTNVIHIDINEDNTYKIKNIIKENSKSEILELLDYSSDNLVESIRINTEFAINNKTLSIEEARKLIDQIETSL
RKSSYLSE

Sequences:

>Translated_648_residues
MTNFDSKKLNKHWTIEDSISTYGIDKWGDQYFSINSLGNISITPNRNSKKTIDLFKLVNEIKSREINTPLILRFNDILKD
RITELNNAFSQAIETYNYKNIFQGVFPIKCNQQKNVLEKIIEYGDYWDFGLEVGSKSELLIGLSLLENKKSLLICNGYKD
KKYIEIAILARKLGKQPIIVIEQIDEVQRIIEAVKNLRSTPILGIRSKLSSKSSGRWGKSVGDNSKFGLSIPEIMLTIKE
LKEASLINEMKLLHFHIGSQISDISVIKDALQEASQIFVELSKLGAPMKYIDVGGGLGIDFDGTKTSSNTSTNYSLQNYA
NDVVATIKDSCEVNNIQHPIIISESGRAIVSHCSVLIFDVLGTSHVSSQIKVSHQKKTSLIIKNLIDTHNQLKNLRNKKE
DLSEIIELWNDAKKFKKDCLVAFRLGFISLGERAYAEELTWACAKEISSHLDNEKIIHPDLSEITETLSSTYYANLSVFK
SIPDTWAINQIFPIIPIHRHLEEPICKGNFADLTCDSDGKLNNFIDNGKIKSLLNLHRPEENNDYLIGIFMAGAYQEALG
NFHNLFGNTNVIHIDINEDNTYKIKNIIKENSKSEILELLDYSSDNLVESIRINTEFAINNKTLSIEEARKLIDQIETSL
RKSSYLSE
>Mature_647_residues
TNFDSKKLNKHWTIEDSISTYGIDKWGDQYFSINSLGNISITPNRNSKKTIDLFKLVNEIKSREINTPLILRFNDILKDR
ITELNNAFSQAIETYNYKNIFQGVFPIKCNQQKNVLEKIIEYGDYWDFGLEVGSKSELLIGLSLLENKKSLLICNGYKDK
KYIEIAILARKLGKQPIIVIEQIDEVQRIIEAVKNLRSTPILGIRSKLSSKSSGRWGKSVGDNSKFGLSIPEIMLTIKEL
KEASLINEMKLLHFHIGSQISDISVIKDALQEASQIFVELSKLGAPMKYIDVGGGLGIDFDGTKTSSNTSTNYSLQNYAN
DVVATIKDSCEVNNIQHPIIISESGRAIVSHCSVLIFDVLGTSHVSSQIKVSHQKKTSLIIKNLIDTHNQLKNLRNKKED
LSEIIELWNDAKKFKKDCLVAFRLGFISLGERAYAEELTWACAKEISSHLDNEKIIHPDLSEITETLSSTYYANLSVFKS
IPDTWAINQIFPIIPIHRHLEEPICKGNFADLTCDSDGKLNNFIDNGKIKSLLNLHRPEENNDYLIGIFMAGAYQEALGN
FHNLFGNTNVIHIDINEDNTYKIKNIIKENSKSEILELLDYSSDNLVESIRINTEFAINNKTLSIEEARKLIDQIETSLR
KSSYLSE

Specific function: Catalyzes the biosynthesis of agmatine from arginine

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily

Homologues:

Organism=Escherichia coli, GI1789307, Length=632, Percent_Identity=32.753164556962, Blast_Score=437, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEA_PROM5 (A2BU00)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001010368.1
- STRING:   A2BU00
- GeneID:   4719928
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_00521
- eggNOG:   COG1166
- HOGENOM:   HBG321436
- OMA:   TCDSDGE
- ProtClustDB:   PRK05354
- BioCyc:   PMAR167542:P9515ORF_0053-MONOMER
- HAMAP:   MF_01417
- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183
- Gene3D:   G3DSA:2.40.37.10
- PANTHER:   PTHR11482:SF3
- PIRSF:   PIRSF001336
- PRINTS:   PR01180
- PRINTS:   PR01179
- TIGRFAMs:   TIGR01273

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC; SSF50621 Racem_decarbox_C

EC number: =4.1.1.19

Molecular weight: Translated: 73325; Mature: 73193

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00878 ODR_DC_2_1; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNFDSKKLNKHWTIEDSISTYGIDKWGDQYFSINSLGNISITPNRNSKKTIDLFKLVNE
CCCCCCCCCCCCCEEECCHHHCCCCHHCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHH
IKSREINTPLILRFNDILKDRITELNNAFSQAIETYNYKNIFQGVFPIKCNQQKNVLEKI
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCCHHHHHHHH
IEYGDYWDFGLEVGSKSELLIGLSLLENKKSLLICNGYKDKKYIEIAILARKLGKQPIIV
HHHCCCEEECCCCCCCCCEEEEHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEE
IEQIDEVQRIIEAVKNLRSTPILGIRSKLSSKSSGRWGKSVGDNSKFGLSIPEIMLTIKE
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LKEASLINEMKLLHFHIGSQISDISVIKDALQEASQIFVELSKLGAPMKYIDVGGGLGID
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
FDGTKTSSNTSTNYSLQNYANDVVATIKDSCEVNNIQHPIIISESGRAIVSHCSVLIFDV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHH
LGTSHVSSQIKVSHQKKTSLIIKNLIDTHNQLKNLRNKKEDLSEIIELWNDAKKFKKDCL
HCCHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAFRLGFISLGERAYAEELTWACAKEISSHLDNEKIIHPDLSEITETLSSTYYANLSVFK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHH
SIPDTWAINQIFPIIPIHRHLEEPICKGNFADLTCDSDGKLNNFIDNGKIKSLLNLHRPE
CCCCCHHHHHHCCCCCHHHHHCCCCCCCCCCEEEECCCCCHHHHHCCCHHHHHHHHCCCC
ENNDYLIGIFMAGAYQEALGNFHNLFGNTNVIHIDINEDNTYKIKNIIKENSKSEILELL
CCCCEEEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHH
DYSSDNLVESIRINTEFAINNKTLSIEEARKLIDQIETSLRKSSYLSE
HCCCCCHHHHEEECEEEEECCCEECHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TNFDSKKLNKHWTIEDSISTYGIDKWGDQYFSINSLGNISITPNRNSKKTIDLFKLVNE
CCCCCCCCCCCCEEECCHHHCCCCHHCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHH
IKSREINTPLILRFNDILKDRITELNNAFSQAIETYNYKNIFQGVFPIKCNQQKNVLEKI
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCCHHHHHHHH
IEYGDYWDFGLEVGSKSELLIGLSLLENKKSLLICNGYKDKKYIEIAILARKLGKQPIIV
HHHCCCEEECCCCCCCCCEEEEHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEE
IEQIDEVQRIIEAVKNLRSTPILGIRSKLSSKSSGRWGKSVGDNSKFGLSIPEIMLTIKE
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LKEASLINEMKLLHFHIGSQISDISVIKDALQEASQIFVELSKLGAPMKYIDVGGGLGID
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
FDGTKTSSNTSTNYSLQNYANDVVATIKDSCEVNNIQHPIIISESGRAIVSHCSVLIFDV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHH
LGTSHVSSQIKVSHQKKTSLIIKNLIDTHNQLKNLRNKKEDLSEIIELWNDAKKFKKDCL
HCCHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAFRLGFISLGERAYAEELTWACAKEISSHLDNEKIIHPDLSEITETLSSTYYANLSVFK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHH
SIPDTWAINQIFPIIPIHRHLEEPICKGNFADLTCDSDGKLNNFIDNGKIKSLLNLHRPE
CCCCCHHHHHHCCCCCHHHHHCCCCCCCCCCEEEECCCCCHHHHHCCCHHHHHHHHCCCC
ENNDYLIGIFMAGAYQEALGNFHNLFGNTNVIHIDINEDNTYKIKNIIKENSKSEILELL
CCCCEEEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHH
DYSSDNLVESIRINTEFAINNKTLSIEEARKLIDQIETSLRKSSYLSE
HCCCCCHHHHEEECEEEEECCCEECHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA