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The map label for this gene is dhsS

Identifier: 123965269

GI number: 123965269

Start: 32651

End: 33814

Strand: Reverse

Name: dhsS

Synonym: P9515_00341

Alternate gene names: NA

Gene position: 33814-32651 (Counterclockwise)

Preceding gene: 123965272

Following gene: 123965267

Centisome position: 1.98

GC content: 34.02

Gene sequence:

>1164_bases
GTGGCCATACAACAAAAATTATCATTGATGATACCTGGTCCCACACCAGTTCCAGAAAAAGTTTTAGAAGCACTTGGAAG
ACATCCCATAGGGCACAGAAGCAAAGATTTTCAAGATCTTGTTGAAATTACAACCAAGAATCTACAATGGTTACACCAAA
CAAAAAATGATGTTTTAACAATAACTGGTAGTGGAACTGCTGCTATGGAAGCAGGAATAATCAGTACATTGAGCAAAGGA
GACAAAGTTATCTGTGGCGAGAACGGGAAATTCGGACAAAGATGGGTAAAAGTTGCGCAAGAATTTGGACTAGAAGTAAT
TAAAATTGATGCAAAATGGGGGAGCCCTCTTGATCCAGAAAATTTCAAAAAGATTTTAGAGAAAGATTATAAAAAAGAAA
TAAAAGCAGTTATCCTCACACATTCAGAAACCTCAACAGGAGTAATTAATGATTTAAAAACGATAAGTTCGCATATTCGT
AATCATAAAAAAGCTTTATCAATTATTGACTGCGTAACAAGTATTGGAGCTTGTGACGTTCCTGTAGATGAGTGGGAGCT
AGATATTGTTGCCTCAGGATCTCAAAAAGGATACATGATACCTCCAGGCTTAAGCTTTGTGTCTATGAGTCAAAAAGCAT
GGAAAGCTTCAGAAGCATCTAATTTACCAAAGTTTTATTTAAATTTAAAATCATATAAAAAAAGTCTTTCAAGTAATAGC
AATCCCTATACTCCAGCAGTTAACTTAGTTTTTGCCTTAAATGAAGCTTTAAACATGATGAAAGATGAAGGATTAGATTC
AATTTTCGCGAGGCATAAAAAACATAGATTAGCTGTTAGTGAGGCAGCTAAAACTCTAAATCTCCAATTATTTGCTGATG
AGAACCATTTGAGTCCTTCAGTAACTGCAATACAAATAAAAGATATAGATGCAGAACAATTTAGAAAAACAATAAAAACT
AAATATGATATTTTGCTAGCTGGAGGGCAAGATCATTTAAAAGGTAAAATCTTTAGGGTGGGTCATCTAGGTTATATCAA
CGATCGAGACGTAATTTCAGTGATAGCAGCAATAGGAAATACATTGGTAGAACTAAATAAAATTTCTACCGAACAAGTCG
GTGAAGCATTAAAAATAGCTTCATTTCATCTAAAAGTAACGTAA

Upstream 100 bases:

>100_bases
CTCCGGTTACCCATAAAGGTAAAGAAAATCCTTTTTTCAAATCAAGTAATTGAAAAATATTTTATGACTACTAATCTTAG
AATGACCTATCAATTAAAAA

Downstream 100 bases:

>100_bases
TTCAAGTACCTGGTTCCTCAACATTTCCACCTAATTCAACTATCTTTTTTCTCAAGGATCGTGCCTTTTCTAAATCACCT
TGAGTTTGAGCAACTGCAAG

Product: soluble hydrogenase small subunit

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MAIQQKLSLMIPGPTPVPEKVLEALGRHPIGHRSKDFQDLVEITTKNLQWLHQTKNDVLTITGSGTAAMEAGIISTLSKG
DKVICGENGKFGQRWVKVAQEFGLEVIKIDAKWGSPLDPENFKKILEKDYKKEIKAVILTHSETSTGVINDLKTISSHIR
NHKKALSIIDCVTSIGACDVPVDEWELDIVASGSQKGYMIPPGLSFVSMSQKAWKASEASNLPKFYLNLKSYKKSLSSNS
NPYTPAVNLVFALNEALNMMKDEGLDSIFARHKKHRLAVSEAAKTLNLQLFADENHLSPSVTAIQIKDIDAEQFRKTIKT
KYDILLAGGQDHLKGKIFRVGHLGYINDRDVISVIAAIGNTLVELNKISTEQVGEALKIASFHLKVT

Sequences:

>Translated_387_residues
MAIQQKLSLMIPGPTPVPEKVLEALGRHPIGHRSKDFQDLVEITTKNLQWLHQTKNDVLTITGSGTAAMEAGIISTLSKG
DKVICGENGKFGQRWVKVAQEFGLEVIKIDAKWGSPLDPENFKKILEKDYKKEIKAVILTHSETSTGVINDLKTISSHIR
NHKKALSIIDCVTSIGACDVPVDEWELDIVASGSQKGYMIPPGLSFVSMSQKAWKASEASNLPKFYLNLKSYKKSLSSNS
NPYTPAVNLVFALNEALNMMKDEGLDSIFARHKKHRLAVSEAAKTLNLQLFADENHLSPSVTAIQIKDIDAEQFRKTIKT
KYDILLAGGQDHLKGKIFRVGHLGYINDRDVISVIAAIGNTLVELNKISTEQVGEALKIASFHLKVT
>Mature_386_residues
AIQQKLSLMIPGPTPVPEKVLEALGRHPIGHRSKDFQDLVEITTKNLQWLHQTKNDVLTITGSGTAAMEAGIISTLSKGD
KVICGENGKFGQRWVKVAQEFGLEVIKIDAKWGSPLDPENFKKILEKDYKKEIKAVILTHSETSTGVINDLKTISSHIRN
HKKALSIIDCVTSIGACDVPVDEWELDIVASGSQKGYMIPPGLSFVSMSQKAWKASEASNLPKFYLNLKSYKKSLSSNSN
PYTPAVNLVFALNEALNMMKDEGLDSIFARHKKHRLAVSEAAKTLNLQLFADENHLSPSVTAIQIKDIDAEQFRKTIKTK
YDILLAGGQDHLKGKIFRVGHLGYINDRDVISVIAAIGNTLVELNKISTEQVGEALKIASFHLKVT

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=351, Percent_Identity=29.9145299145299, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17536281, Length=345, Percent_Identity=28.9855072463768, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321079, Length=361, Percent_Identity=26.5927977839335, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17530823, Length=371, Percent_Identity=25.8760107816712, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42665; Mature: 42534

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQQKLSLMIPGPTPVPEKVLEALGRHPIGHRSKDFQDLVEITTKNLQWLHQTKNDVLT
CCCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
ITGSGTAAMEAGIISTLSKGDKVICGENGKFGQRWVKVAQEFGLEVIKIDAKWGSPLDPE
EECCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHH
NFKKILEKDYKKEIKAVILTHSETSTGVINDLKTISSHIRNHKKALSIIDCVTSIGACDV
HHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVDEWELDIVASGSQKGYMIPPGLSFVSMSQKAWKASEASNLPKFYLNLKSYKKSLSSNS
CCCCEEEEEEECCCCCCEECCCCCHHHHHHHHHHCCHHHCCCCHHEEEHHHHHHHHCCCC
NPYTPAVNLVFALNEALNMMKDEGLDSIFARHKKHRLAVSEAAKTLNLQLFADENHLSPS
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCC
VTAIQIKDIDAEQFRKTIKTKYDILLAGGQDHLKGKIFRVGHLGYINDRDVISVIAAIGN
EEEEEEECCCHHHHHHHHCCCEEEEEECCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHH
TLVELNKISTEQVGEALKIASFHLKVT
HHHHHHHCCHHHHHHHHEEEEEEEEEC
>Mature Secondary Structure 
AIQQKLSLMIPGPTPVPEKVLEALGRHPIGHRSKDFQDLVEITTKNLQWLHQTKNDVLT
CCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
ITGSGTAAMEAGIISTLSKGDKVICGENGKFGQRWVKVAQEFGLEVIKIDAKWGSPLDPE
EECCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHH
NFKKILEKDYKKEIKAVILTHSETSTGVINDLKTISSHIRNHKKALSIIDCVTSIGACDV
HHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVDEWELDIVASGSQKGYMIPPGLSFVSMSQKAWKASEASNLPKFYLNLKSYKKSLSSNS
CCCCEEEEEEECCCCCCEECCCCCHHHHHHHHHHCCHHHCCCCHHEEEHHHHHHHHCCCC
NPYTPAVNLVFALNEALNMMKDEGLDSIFARHKKHRLAVSEAAKTLNLQLFADENHLSPS
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCC
VTAIQIKDIDAEQFRKTIKTKYDILLAGGQDHLKGKIFRVGHLGYINDRDVISVIAAIGN
EEEEEEECCCHHHHHHHHCCCEEEEEECCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHH
TLVELNKISTEQVGEALKIASFHLKVT
HHHHHHHCCHHHHHHHHEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2129525 [H]