Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 123965258

GI number: 123965258

Start: 25172

End: 26158

Strand: Reverse

Name: thiL [H]

Synonym: P9515_00231

Alternate gene names: 123965258

Gene position: 26158-25172 (Counterclockwise)

Preceding gene: 123965259

Following gene: 123965256

Centisome position: 1.53

GC content: 30.29

Gene sequence:

>987_bases
ATGCATAAAGAACTACTTGAAGATATTGGCGAAAAAGAATTAATAAAAAGGCTTGCTGAATTTATGCCAGAAAATCAAGT
CTCCGATGATTGCGCATTTGTTAAAACTAAAAATACAAACTTACTTATTAATACTGATTCACTAGTTGAAAATATCCATT
TTAATAATGATACAATTTCTGCAATTGATATAGGATGGAAAGCCGTAGCATGCAATGTATCTGACTTAATCTCAAGTGGA
TGCAACAAAATCATAGGAATTACTATTGGATTAGTGGTTCCTTCAAATACAGATTGGATTTGGATTAAAGATTTATATAC
AGGAATAAATCTAGCTTTAGACCATTTCGGAGGCTTAATCCTTGGTGGGGATTGTTCTGTGGGAAAAGAAAAAGTAATTT
CTGTGACTGCTCTAGGAACACAAGGAGAACTAAAATTAAGGAGAAACTCATGCAAACCTAAAGAAATCATCTTGACTACA
GGAATTCATGGCCTCAGCAAATTAGGATTAATGATAAAAAATAAAACAAATTTTGATAAAAATATTTCTCTAACAAAGTC
ATTAGTCAATAGTTCTTTACAACAATTTCGCAAACCAAAACTTAAAACTGAATTTCTTAAAAAAGTACTTAAAGCTCGCC
CTAACAAAAGCATTGATACTATTGGTTGTACTGATAGCAGTGATGGATTATTTCAAGCATTATTAGATTTAGCAACTGAA
AGTAATTGCAAAGCGATTATTGATTATAAAAAAATACCTAAACATAAAAATTGGCCTAAAGGAGATAAATGGGACGAATA
TTACTTTTTTGGAGGCGAAGATTATGAGCTAGTTTTTTCTCTCCCAAGAAAATGGGCAGATAATCTTTTATGTACAGATA
AAACTATTACGGAAATCGGATATTTTATAAATGGAGATGCTGCAATCGATTTTAAAAATTGCAATAACAAAAATCTATTT
ACAAATAAATCTTTTTCTCACTTTTGA

Upstream 100 bases:

>100_bases
GGTTATGTAATTGAGGGCTCTGAAGTTTTAGAAGAACTAACAAAAGACGACACAATCATCTCAATTGATGTTTTAAGTGG
AATGGATAAACTGAAATTAA

Downstream 100 bases:

>100_bases
TTATTCCCATTTTTTAGCAACTATTTCAGCTAAATCTACAACTCTTTGACTGTAACCCCATTCATTATCGTACCAAGCAA
GAACTTTTACCAAATTATCT

Product: putative thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MHKELLEDIGEKELIKRLAEFMPENQVSDDCAFVKTKNTNLLINTDSLVENIHFNNDTISAIDIGWKAVACNVSDLISSG
CNKIIGITIGLVVPSNTDWIWIKDLYTGINLALDHFGGLILGGDCSVGKEKVISVTALGTQGELKLRRNSCKPKEIILTT
GIHGLSKLGLMIKNKTNFDKNISLTKSLVNSSLQQFRKPKLKTEFLKKVLKARPNKSIDTIGCTDSSDGLFQALLDLATE
SNCKAIIDYKKIPKHKNWPKGDKWDEYYFFGGEDYELVFSLPRKWADNLLCTDKTITEIGYFINGDAAIDFKNCNNKNLF
TNKSFSHF

Sequences:

>Translated_328_residues
MHKELLEDIGEKELIKRLAEFMPENQVSDDCAFVKTKNTNLLINTDSLVENIHFNNDTISAIDIGWKAVACNVSDLISSG
CNKIIGITIGLVVPSNTDWIWIKDLYTGINLALDHFGGLILGGDCSVGKEKVISVTALGTQGELKLRRNSCKPKEIILTT
GIHGLSKLGLMIKNKTNFDKNISLTKSLVNSSLQQFRKPKLKTEFLKKVLKARPNKSIDTIGCTDSSDGLFQALLDLATE
SNCKAIIDYKKIPKHKNWPKGDKWDEYYFFGGEDYELVFSLPRKWADNLLCTDKTITEIGYFINGDAAIDFKNCNNKNLF
TNKSFSHF
>Mature_328_residues
MHKELLEDIGEKELIKRLAEFMPENQVSDDCAFVKTKNTNLLINTDSLVENIHFNNDTISAIDIGWKAVACNVSDLISSG
CNKIIGITIGLVVPSNTDWIWIKDLYTGINLALDHFGGLILGGDCSVGKEKVISVTALGTQGELKLRRNSCKPKEIILTT
GIHGLSKLGLMIKNKTNFDKNISLTKSLVNSSLQQFRKPKLKTEFLKKVLKARPNKSIDTIGCTDSSDGLFQALLDLATE
SNCKAIIDYKKIPKHKNWPKGDKWDEYYFFGGEDYELVFSLPRKWADNLLCTDKTITEIGYFINGDAAIDFKNCNNKNLF
TNKSFSHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=290, Percent_Identity=28.9655172413793, Blast_Score=88, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 36723; Mature: 36723

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKELLEDIGEKELIKRLAEFMPENQVSDDCAFVKTKNTNLLINTDSLVENIHFNNDTIS
CCHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECHHHHHHCCCCCCEEE
AIDIGWKAVACNVSDLISSGCNKIIGITIGLVVPSNTDWIWIKDLYTGINLALDHFGGLI
EEECCCEEEEECHHHHHHHCCCEEEEEEEEEEEECCCCEEEEHHHHHHHHHHHHHCCCEE
LGGDCSVGKEKVISVTALGTQGELKLRRNSCKPKEIILTTGIHGLSKLGLMIKNKTNFDK
EECCCCCCCCCEEEEEEECCCCCEEEECCCCCCCEEEEECCCHHHHHHCEEEECCCCCCC
NISLTKSLVNSSLQQFRKPKLKTEFLKKVLKARPNKSIDTIGCTDSSDGLFQALLDLATE
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHCC
SNCKAIIDYKKIPKHKNWPKGDKWDEYYFFGGEDYELVFSLPRKWADNLLCTDKTITEIG
CCCEEEEEHHHCCCCCCCCCCCCCCCEEEECCCCEEEEEECHHHHHCCEEECCCHHHHHC
YFINGDAAIDFKNCNNKNLFTNKSFSHF
EEECCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHKELLEDIGEKELIKRLAEFMPENQVSDDCAFVKTKNTNLLINTDSLVENIHFNNDTIS
CCHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECHHHHHHCCCCCCEEE
AIDIGWKAVACNVSDLISSGCNKIIGITIGLVVPSNTDWIWIKDLYTGINLALDHFGGLI
EEECCCEEEEECHHHHHHHCCCEEEEEEEEEEEECCCCEEEEHHHHHHHHHHHHHCCCEE
LGGDCSVGKEKVISVTALGTQGELKLRRNSCKPKEIILTTGIHGLSKLGLMIKNKTNFDK
EECCCCCCCCCEEEEEEECCCCCEEEECCCCCCCEEEEECCCHHHHHHCEEEECCCCCCC
NISLTKSLVNSSLQQFRKPKLKTEFLKKVLKARPNKSIDTIGCTDSSDGLFQALLDLATE
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHCC
SNCKAIIDYKKIPKHKNWPKGDKWDEYYFFGGEDYELVFSLPRKWADNLLCTDKTITEIG
CCCEEEEEHHHCCCCCCCCCCCCCCCEEEECCCCEEEEEECHHHHHCCEEECCCHHHHHC
YFINGDAAIDFKNCNNKNLFTNKSFSHF
EEECCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA