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The map label for this gene is atpH

Identifier: 121999211

GI number: 121999211

Start: 2673996

End: 2674532

Strand: Reverse

Name: atpH

Synonym: Hhal_2433

Alternate gene names: 121999211

Gene position: 2674532-2673996 (Counterclockwise)

Preceding gene: 121999212

Following gene: 121999210

Centisome position: 99.85

GC content: 68.34

Gene sequence:

>537_bases
ATGGCCGAGCGCAGCACACTGGCCCGACCTTACGCGCGCGCCGTCTTCGAGCTTGCCGGTGACGACGCGACCGAGCGCCA
GGCTTGGTCGCGTCGGCTTGCGGCGGTGGCCGAGGTGGTGCAGGTGCCCCAGCTCGCTTCGTTGCTCACCCACCCGCGGA
TCAGCGCCGAGCAACTCGCCGGCATTGTCTGCGAGGCGGCTGGCGACCTAGGGCAGACCGGCGAGAACTTTGTCCGGCTG
CTGGCGAGCAACCGGCGACTGCAGTATGCGCCGGAAGTCGCTCGGGTCTACGAAGAGCTGCGTGCCGAGGCCGAGGGCAT
CGTCGACGTAGAGGTGCTTTCGGCGACCCAGCTCGAGGACGCGCAGCAAGAACGCCTGGCCGAAGCGCTCCGTAAGCGCC
TCGGCCGAGAGGTGCGGCTGCAGACGCGGGTCGATGAGTCCCTCATCGGCGGGGCGATGATCCGCGCTGGCGACACCACC
ATAGACGGCTCGGTGAAGGGCAAACTGGCCCGCCTCTCGAGTGCACTGGTTCATTGA

Upstream 100 bases:

>100_bases
CGCCGTCCAGGCGAGCAGCCAGATCCTGAAGCGCGAGGTGGACGCCAAGGCGCACAAGGATCTGATCGACGAACTGGCGA
CGCAAATCTAGGGAGGCGCC

Downstream 100 bases:

>100_bases
CGAGGTAGGACGATGCAAGTCAATCCATCGGAGATCAGCGAGCTCATCAAGCGTCGCATTGAGAACTTCGACGCGGCGGC
TGAGGCCCGCAACGAAGGCA

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MAERSTLARPYARAVFELAGDDATERQAWSRRLAAVAEVVQVPQLASLLTHPRISAEQLAGIVCEAAGDLGQTGENFVRL
LASNRRLQYAPEVARVYEELRAEAEGIVDVEVLSATQLEDAQQERLAEALRKRLGREVRLQTRVDESLIGGAMIRAGDTT
IDGSVKGKLARLSSALVH

Sequences:

>Translated_178_residues
MAERSTLARPYARAVFELAGDDATERQAWSRRLAAVAEVVQVPQLASLLTHPRISAEQLAGIVCEAAGDLGQTGENFVRL
LASNRRLQYAPEVARVYEELRAEAEGIVDVEVLSATQLEDAQQERLAEALRKRLGREVRLQTRVDESLIGGAMIRAGDTT
IDGSVKGKLARLSSALVH
>Mature_177_residues
AERSTLARPYARAVFELAGDDATERQAWSRRLAAVAEVVQVPQLASLLTHPRISAEQLAGIVCEAAGDLGQTGENFVRLL
ASNRRLQYAPEVARVYEELRAEAEGIVDVEVLSATQLEDAQQERLAEALRKRLGREVRLQTRVDESLIGGAMIRAGDTTI
DGSVKGKLARLSSALVH

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=172, Percent_Identity=28.4883720930233, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1790173, Length=180, Percent_Identity=40, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_HALHL (A1WZT4)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003998.1
- ProteinModelPortal:   A1WZT4
- STRING:   A1WZT4
- GeneID:   4710558
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2433
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   FIAICGE
- PhylomeDB:   A1WZT4
- ProtClustDB:   PRK05758
- BioCyc:   HHAL349124:HHAL_2433-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19388; Mature: 19257

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERSTLARPYARAVFELAGDDATERQAWSRRLAAVAEVVQVPQLASLLTHPRISAEQLA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GIVCEAAGDLGQTGENFVRLLASNRRLQYAPEVARVYEELRAEAEGIVDVEVLSATQLED
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AQQERLAEALRKRLGREVRLQTRVDESLIGGAMIRAGDTTIDGSVKGKLARLSSALVH
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AERSTLARPYARAVFELAGDDATERQAWSRRLAAVAEVVQVPQLASLLTHPRISAEQLA
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GIVCEAAGDLGQTGENFVRLLASNRRLQYAPEVARVYEELRAEAEGIVDVEVLSATQLED
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AQQERLAEALRKRLGREVRLQTRVDESLIGGAMIRAGDTTIDGSVKGKLARLSSALVH
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA