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The map label for this gene is epsM [H]

Identifier: 121999165

GI number: 121999165

Start: 2624409

End: 2624933

Strand: Reverse

Name: epsM [H]

Synonym: Hhal_2387

Alternate gene names: 121999165

Gene position: 2624933-2624409 (Counterclockwise)

Preceding gene: 121999166

Following gene: 121999164

Centisome position: 98.0

GC content: 68.38

Gene sequence:

>525_bases
GTGATCCGCGAGGCGCTGCAGCAGCTCCGCGCCGAGGCTGAACGCTTCTGGTCGGCGCGTAACCCTCGGGAACGCTGGCT
GCTGGGTAGCGGCGGCTTGCTGGTGCTGGTGGTGGTGCCGTACGTGGCGGTTTGGGAGCCGTTGACCGAGCGTCGGGACC
AGCTCCAAGCTCAGGTCGCCGAGCAGCGCCAGGATCTGGCCTGGATGCGCTCGGCCGCGGAAGAGATCCACGCCCATGAT
GGGGATAACGGTTCGGCAGAGCCGGTCACCGACGAGCGATCCCTGCTCAGCCTGGTGGATCGGGCCGCCCGGGAGGCCGG
GATCGATGATCAGCTCAGCCGGGTGCAGCCGGACGGGGATGGCACCCTCCGGGTGTGGATGGACCGGGTCCCCTTCGATG
AGCTCATGAACTGGCTCGACGGCCTGCAGCGCGCCGCCGGCGTTGAGGTAGATGCCTTGACTGTGGAGCGGACGCAAGAG
GACGGCTTGGTCAACGTGCGCCTGACCCTGGAGGTGGGCACGTGA

Upstream 100 bases:

>100_bases
CGCTGGAGGGCGACGCCGGCCTGGCCGTCGAGATCCGCTCGGCGTCGGCGCGGGAGGGTCGCGTGGACGGTCGCCTGGTC
ATTCGCGAAGAGGAGTCGGC

Downstream 100 bases:

>100_bases
CCGCCGCCCGCCCGTGGGTCCGGTTGTTGCGACGTCGAAGCCGGGGTGCGCCCCGGCTCAGGTGGCCGGGGCGACGATTC
TGGGGGTTCACGGTGCTGGG

Product: general secretion pathway M protein

Products: NA

Alternate protein names: Cholera toxin secretion protein epsM [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MIREALQQLRAEAERFWSARNPRERWLLGSGGLLVLVVVPYVAVWEPLTERRDQLQAQVAEQRQDLAWMRSAAEEIHAHD
GDNGSAEPVTDERSLLSLVDRAAREAGIDDQLSRVQPDGDGTLRVWMDRVPFDELMNWLDGLQRAAGVEVDALTVERTQE
DGLVNVRLTLEVGT

Sequences:

>Translated_174_residues
MIREALQQLRAEAERFWSARNPRERWLLGSGGLLVLVVVPYVAVWEPLTERRDQLQAQVAEQRQDLAWMRSAAEEIHAHD
GDNGSAEPVTDERSLLSLVDRAAREAGIDDQLSRVQPDGDGTLRVWMDRVPFDELMNWLDGLQRAAGVEVDALTVERTQE
DGLVNVRLTLEVGT
>Mature_174_residues
MIREALQQLRAEAERFWSARNPRERWLLGSGGLLVLVVVPYVAVWEPLTERRDQLQAQVAEQRQDLAWMRSAAEEIHAHD
GDNGSAEPVTDERSLLSLVDRAAREAGIDDQLSRVQPDGDGTLRVWMDRVPFDELMNWLDGLQRAAGVEVDALTVERTQE
DGLVNVRLTLEVGT

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: COG3149

COG function: function code U; Type II secretory pathway, component PulM

Gene ontology:

Cell location: Cell inner membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP M family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007690
- InterPro:   IPR023229 [H]

Pfam domain/function: PF04612 GspM [H]

EC number: NA

Molecular weight: Translated: 19624; Mature: 19624

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIREALQQLRAEAERFWSARNPRERWLLGSGGLLVLVVVPYVAVWEPLTERRDQLQAQVA
CHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQRQDLAWMRSAAEEIHAHDGDNGSAEPVTDERSLLSLVDRAAREAGIDDQLSRVQPDGD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
GTLRVWMDRVPFDELMNWLDGLQRAAGVEVDALTVERTQEDGLVNVRLTLEVGT
CEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEEEECC
>Mature Secondary Structure
MIREALQQLRAEAERFWSARNPRERWLLGSGGLLVLVVVPYVAVWEPLTERRDQLQAQVA
CHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQRQDLAWMRSAAEEIHAHDGDNGSAEPVTDERSLLSLVDRAAREAGIDDQLSRVQPDGD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
GTLRVWMDRVPFDELMNWLDGLQRAAGVEVDALTVERTQEDGLVNVRLTLEVGT
CEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8406031; 10952301 [H]