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The map label for this gene is pabB [H]

Identifier: 121998987

GI number: 121998987

Start: 2422735

End: 2424120

Strand: Reverse

Name: pabB [H]

Synonym: Hhal_2208

Alternate gene names: 121998987

Gene position: 2424120-2422735 (Counterclockwise)

Preceding gene: 121998999

Following gene: 121998985

Centisome position: 90.5

GC content: 71.72

Gene sequence:

>1386_bases
GTGTCCTTACCCCTGCAATCTCGATCCCTGCCGTACATCGGTGACGGGGCAACGGCGATGCGCGTCCTGGGGGGCGAACC
GTGGTCAGCGTGGCTCGACTCGGGCCACGGCGGCTGTGCCGGGGCGCGTTACGACATCCTCGTCGCCCGGCCGACGGTCA
CGCTGATCGCAGCCGGCGGGCAGACCACCATCCGGCGCGGCGAGCGGGTCGAGCGCCGGCACGGCGATCCGCTGGCCCAC
CTGGCTGCTGAGCTCGATGCCCTCGGCCCGCTCCCCGTTGACCCTCGGTGGCCGTTCACCGGCGGCGCGGTGGGGTATTT
CGGCTACGACCTGGGGCGCCGCCTGATGGGGGTTCCGGGTGCCGATCCCGCGTTGCCCGAGATGGCCGTGGGGATCTACG
AGCACGCGGTAATCACCGACCATCGCCACGAATGCAGCACTGCGGTGGGGCGACGCCTGGATGAGGCCTGGCTGGCGGAC
GTGGCCTGCCGCCGGGAGACGGGGGCGAGACCGCAGCCGTGGTCGACCGCAGGTCCGGTCCTCCGTGAACCGGACGCCGA
TGGGTACGCGGCCGCTTTCCGTCGGGTGCAGGGGTATCTGCACGCCGGTGACTGCTACCAGGTCAATCTGGCCCGGCGCT
TCTCGGTGCCCTGCTGCGGGGATCCCCAGGCGGCGTACCTCGCCCTGCGCGCAGCCTCGTCGGCGCCCTTTGCGGCGTGG
CTCCGCTTCCCCGGGGGCGATGTGCTCAGCCTCTCGCCGGAGCGCTTCTTGCACATCGACGGCGACGGGCGGGTGACCAC
CGAGCCGATCAAGGGCACCCGGCCGCGGTTCACCGATCCCGCCGAGGATGAGGCGGCCCGCCGGGACCTGCTGGGCAGCG
CCAAGGATCGGGCCGAGAACGTGATGATCGTCGATCTGCTGCGCAACGACCTGGGCAAGGGGTGCGAGGTGGGCAGCGTG
CGGGTGCCGTCGCTCTGCCGCGCCGAGCGCTTTGCCAGCGTGCACCACTTGGTCAGTACTGTCACCGGGCGCCTGGCCCC
GGGGCGGCGCGCCACCGATCTGCTGCGCGATTGCCTGCCCGGTGGCTCCATCACCGGGGCGCCGAAGCGCCGTGCCATGG
AGATCATCACCGAGCTCGAGCCGGGACCGCGCGGGGTCTACTGTGGGGCCATCGGTTACCTGGGGCTGGATGGCCGCATG
GACACCAGCATTGCCATTCGCACCGCGACGTGCAGCGACGGCAGTATGACCTACTGGGCCGGTGGCGGGGTGGTGGCGGA
CTCCACCGCTGCCGCCGAGCTCCAGGAGACGGAAGACAAGGCCGCTGGTTTTCTGTCGCTGGCCGAGGGCGGCCAGGCCG
CGGCAGGGGTCAGGCCTCGCCGCTGA

Upstream 100 bases:

>100_bases
ATGCCGCATGGCCTTGGTCGGTCATGATTCTCCTCCGTCGACCGTAGGTTTTTTTATCGTTGCGAGGTTAAACGATCTGA
GCTGTCCGGAGCACCATTAC

Downstream 100 bases:

>100_bases
GCAGTTGTGCGAACGCCGCCAGGGCCTCGTACTCCTCACGGCACGCGTTGCCGATGCGTTCGAGCTTGCCCTGCGGGATG
GGCGGGGCGTCGGCGCACTG

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSLPLQSRSLPYIGDGATAMRVLGGEPWSAWLDSGHGGCAGARYDILVARPTVTLIAAGGQTTIRRGERVERRHGDPLAH
LAAELDALGPLPVDPRWPFTGGAVGYFGYDLGRRLMGVPGADPALPEMAVGIYEHAVITDHRHECSTAVGRRLDEAWLAD
VACRRETGARPQPWSTAGPVLREPDADGYAAAFRRVQGYLHAGDCYQVNLARRFSVPCCGDPQAAYLALRAASSAPFAAW
LRFPGGDVLSLSPERFLHIDGDGRVTTEPIKGTRPRFTDPAEDEAARRDLLGSAKDRAENVMIVDLLRNDLGKGCEVGSV
RVPSLCRAERFASVHHLVSTVTGRLAPGRRATDLLRDCLPGGSITGAPKRRAMEIITELEPGPRGVYCGAIGYLGLDGRM
DTSIAIRTATCSDGSMTYWAGGGVVADSTAAAELQETEDKAAGFLSLAEGGQAAAGVRPRR

Sequences:

>Translated_461_residues
MSLPLQSRSLPYIGDGATAMRVLGGEPWSAWLDSGHGGCAGARYDILVARPTVTLIAAGGQTTIRRGERVERRHGDPLAH
LAAELDALGPLPVDPRWPFTGGAVGYFGYDLGRRLMGVPGADPALPEMAVGIYEHAVITDHRHECSTAVGRRLDEAWLAD
VACRRETGARPQPWSTAGPVLREPDADGYAAAFRRVQGYLHAGDCYQVNLARRFSVPCCGDPQAAYLALRAASSAPFAAW
LRFPGGDVLSLSPERFLHIDGDGRVTTEPIKGTRPRFTDPAEDEAARRDLLGSAKDRAENVMIVDLLRNDLGKGCEVGSV
RVPSLCRAERFASVHHLVSTVTGRLAPGRRATDLLRDCLPGGSITGAPKRRAMEIITELEPGPRGVYCGAIGYLGLDGRM
DTSIAIRTATCSDGSMTYWAGGGVVADSTAAAELQETEDKAAGFLSLAEGGQAAAGVRPRR
>Mature_460_residues
SLPLQSRSLPYIGDGATAMRVLGGEPWSAWLDSGHGGCAGARYDILVARPTVTLIAAGGQTTIRRGERVERRHGDPLAHL
AAELDALGPLPVDPRWPFTGGAVGYFGYDLGRRLMGVPGADPALPEMAVGIYEHAVITDHRHECSTAVGRRLDEAWLADV
ACRRETGARPQPWSTAGPVLREPDADGYAAAFRRVQGYLHAGDCYQVNLARRFSVPCCGDPQAAYLALRAASSAPFAAWL
RFPGGDVLSLSPERFLHIDGDGRVTTEPIKGTRPRFTDPAEDEAARRDLLGSAKDRAENVMIVDLLRNDLGKGCEVGSVR
VPSLCRAERFASVHHLVSTVTGRLAPGRRATDLLRDCLPGGSITGAPKRRAMEIITELEPGPRGVYCGAIGYLGLDGRMD
TSIAIRTATCSDGSMTYWAGGGVVADSTAAAELQETEDKAAGFLSLAEGGQAAAGVRPRR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=435, Percent_Identity=48.2758620689655, Blast_Score=367, Evalue=1e-103,
Organism=Escherichia coli, GI1787518, Length=383, Percent_Identity=33.1592689295039, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1786809, Length=267, Percent_Identity=25.0936329588015, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082077, Length=290, Percent_Identity=26.551724137931, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=411, Percent_Identity=31.8734793187348, Blast_Score=190, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6324361, Length=396, Percent_Identity=29.5454545454545, Blast_Score=151, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 49060; Mature: 48929

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPLQSRSLPYIGDGATAMRVLGGEPWSAWLDSGHGGCAGARYDILVARPTVTLIAAGG
CCCCCCCCCCCEECCCHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEEECCCEEEEECCC
QTTIRRGERVERRHGDPLAHLAAELDALGPLPVDPRWPFTGGAVGYFGYDLGRRLMGVPG
CHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
ADPALPEMAVGIYEHAVITDHRHECSTAVGRRLDEAWLADVACRRETGARPQPWSTAGPV
CCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LREPDADGYAAAFRRVQGYLHAGDCYQVNLARRFSVPCCGDPQAAYLALRAASSAPFAAW
CCCCCCCHHHHHHHHHHCEEECCCEEEEEEHHHCCCCCCCCCHHHEEEEECCCCCCCEEE
LRFPGGDVLSLSPERFLHIDGDGRVTTEPIKGTRPRFTDPAEDEAARRDLLGSAKDRAEN
EECCCCCEEEECCCCEEEECCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCC
VMIVDLLRNDLGKGCEVGSVRVPSLCRAERFASVHHLVSTVTGRLAPGRRATDLLRDCLP
EEEHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
GGSITGAPKRRAMEIITELEPGPRGVYCGAIGYLGLDGRMDTSIAIRTATCSDGSMTYWA
CCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCEEEEEEEECCCCCEEEEE
GGGVVADSTAAAELQETEDKAAGFLSLAEGGQAAAGVRPRR
CCCEEECCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SLPLQSRSLPYIGDGATAMRVLGGEPWSAWLDSGHGGCAGARYDILVARPTVTLIAAGG
CCCCCCCCCCEECCCHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEEECCCEEEEECCC
QTTIRRGERVERRHGDPLAHLAAELDALGPLPVDPRWPFTGGAVGYFGYDLGRRLMGVPG
CHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
ADPALPEMAVGIYEHAVITDHRHECSTAVGRRLDEAWLADVACRRETGARPQPWSTAGPV
CCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LREPDADGYAAAFRRVQGYLHAGDCYQVNLARRFSVPCCGDPQAAYLALRAASSAPFAAW
CCCCCCCHHHHHHHHHHCEEECCCEEEEEEHHHCCCCCCCCCHHHEEEEECCCCCCCEEE
LRFPGGDVLSLSPERFLHIDGDGRVTTEPIKGTRPRFTDPAEDEAARRDLLGSAKDRAEN
EECCCCCEEEECCCCEEEECCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCC
VMIVDLLRNDLGKGCEVGSVRVPSLCRAERFASVHHLVSTVTGRLAPGRRATDLLRDCLP
EEEHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
GGSITGAPKRRAMEIITELEPGPRGVYCGAIGYLGLDGRMDTSIAIRTATCSDGSMTYWA
CCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCEEEEEEEECCCCCEEEEE
GGGVVADSTAAAELQETEDKAAGFLSLAEGGQAAAGVRPRR
CCCEEECCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]