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The map label for this gene is udg [H]

Identifier: 121998957

GI number: 121998957

Start: 2389535

End: 2390878

Strand: Reverse

Name: udg [H]

Synonym: Hhal_2178

Alternate gene names: 121998957

Gene position: 2390878-2389535 (Counterclockwise)

Preceding gene: 121998958

Following gene: 121998956

Centisome position: 89.26

GC content: 65.48

Gene sequence:

>1344_bases
ATGAAGGTCACGATCTTCGGCAGCGGCTACGTGGGTCTGGTTACCGGGACCTGCTTCGCCGATGCCGGCAACGACGTTGT
CTGTGTCGATATCGACGCGGAGCGCGTCGCGCAGTTGCAGCGCGGTGAGGTCCCCATCTACGAGCCGGGGCTCGACGAGA
TGCTCTCCTTCAACCAGGAGGAGGGGCGGCTGCGCTTTACCACCAATGCCGCCGAGGGGGTGCACCACGGCCTGTTCCAG
TTCATCGCCGTGGGCACGCCTTCGGACGAGGATGGCTCGGCGGACCTGCAGCATGTACTCGCTGTGGCCCGGACCATCGG
CCAGCACATGGATGACTACCGGGTGGTCGTCGATAAGTCCACCGTGCCCGTGGGCACCGCGGACCGGGTGCGCGCCGCGG
TGGGCGAGGAGCTGGCCGCCCGCGGCGAGCAGCTGGAGTACGACGTCGTCTCCAACCCTGAGTTCCTCAAGGAAGGGGCG
GCCATCGACGACTTCGTCAAGCCCGACCGCATCATCATCGGCAGCGACAACCCGCGCACCGGCGAGCTCATGAAGGCGCT
CTACGCGCCGTTCAATCGTAGCCACGACCGGCTGATCGCCATGGATGTGCGCTCTGCGGAGCTGACCAAGTACGCCTCCA
ATGCCATGTTGGCGACCAAGATCAGCTTCATGAACGAGCTCTCCAACCTGGCCGAGCGCCTGGGTGCCGATATCGAGCAG
GTACGGGTGGGGATGGGGTCGGATCCGCGCATCGGCTACCACTTCATTTATCCGGGGTGTGGCTACGGCGGCTCCTGCTT
CCCCAAGGATGTCAAGGCGCTGACCCACACGGCGCACGAGTACGGGTATCAGCCCGAGTTGCTCGAGGCGGTGGAGAGCG
TCAACGCCCGGCAGAAGCAGGTGCTGGTTCATCGTCTGCACGCACACTTTGGCGAGGACCTGGGCGGGCGGACCTTCGGG
CTCTGGGGGTTGGCCTTCAAGCCGAACACCGACGACATGCGTGAAGCCCCCAGTCGTGTCGTCATGGAGGCGCTCTGGGA
AGCCGGGGCGCGGGTCCAGGCCTACGACCCCGAGGCGATGGACGAGGCCGAACGGATCTACGGCAACCGGCAGGATCTGG
AACTCTGCGACAACCTCTACGACGCCGTGGAGGACGCCGACGCGCTGATCGTCTGTACCGAGTGGCAGGTCTTCCGCAGC
CCCGACTTCGAGCGCATCCGGGACGCGCTGCGCCAGCCGGTGGTCTTCGATGGGCGCAATGTCTACCCGCCTTCGATGAT
GGAGGCGCTCGGTTTTACCTACTACGGTATGGGCCGGGGCGAGAGTATTCGTCGCCCCCTCTGA

Upstream 100 bases:

>100_bases
CCCGCAGACGGCCATCGAGCAGGGTTTACCGCAGTTCGTGGCTTGGTATCGAGCGTTTTACGGGGTCTGAGAGGCGGCCC
CTCAAGGAGTGGAGTGAATC

Downstream 100 bases:

>100_bases
GCGCCGGTCGTCCCGAGGCTTGAAACCGGCGGGGGCTGCCTCGATGACCGAGGGTGTGTTGGGCGACAGAGGATGGACTG
TAGATGACGACTGCGCTGAC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKVTIFGSGYVGLVTGTCFADAGNDVVCVDIDAERVAQLQRGEVPIYEPGLDEMLSFNQEEGRLRFTTNAAEGVHHGLFQ
FIAVGTPSDEDGSADLQHVLAVARTIGQHMDDYRVVVDKSTVPVGTADRVRAAVGEELAARGEQLEYDVVSNPEFLKEGA
AIDDFVKPDRIIIGSDNPRTGELMKALYAPFNRSHDRLIAMDVRSAELTKYASNAMLATKISFMNELSNLAERLGADIEQ
VRVGMGSDPRIGYHFIYPGCGYGGSCFPKDVKALTHTAHEYGYQPELLEAVESVNARQKQVLVHRLHAHFGEDLGGRTFG
LWGLAFKPNTDDMREAPSRVVMEALWEAGARVQAYDPEAMDEAERIYGNRQDLELCDNLYDAVEDADALIVCTEWQVFRS
PDFERIRDALRQPVVFDGRNVYPPSMMEALGFTYYGMGRGESIRRPL

Sequences:

>Translated_447_residues
MKVTIFGSGYVGLVTGTCFADAGNDVVCVDIDAERVAQLQRGEVPIYEPGLDEMLSFNQEEGRLRFTTNAAEGVHHGLFQ
FIAVGTPSDEDGSADLQHVLAVARTIGQHMDDYRVVVDKSTVPVGTADRVRAAVGEELAARGEQLEYDVVSNPEFLKEGA
AIDDFVKPDRIIIGSDNPRTGELMKALYAPFNRSHDRLIAMDVRSAELTKYASNAMLATKISFMNELSNLAERLGADIEQ
VRVGMGSDPRIGYHFIYPGCGYGGSCFPKDVKALTHTAHEYGYQPELLEAVESVNARQKQVLVHRLHAHFGEDLGGRTFG
LWGLAFKPNTDDMREAPSRVVMEALWEAGARVQAYDPEAMDEAERIYGNRQDLELCDNLYDAVEDADALIVCTEWQVFRS
PDFERIRDALRQPVVFDGRNVYPPSMMEALGFTYYGMGRGESIRRPL
>Mature_447_residues
MKVTIFGSGYVGLVTGTCFADAGNDVVCVDIDAERVAQLQRGEVPIYEPGLDEMLSFNQEEGRLRFTTNAAEGVHHGLFQ
FIAVGTPSDEDGSADLQHVLAVARTIGQHMDDYRVVVDKSTVPVGTADRVRAAVGEELAARGEQLEYDVVSNPEFLKEGA
AIDDFVKPDRIIIGSDNPRTGELMKALYAPFNRSHDRLIAMDVRSAELTKYASNAMLATKISFMNELSNLAERLGADIEQ
VRVGMGSDPRIGYHFIYPGCGYGGSCFPKDVKALTHTAHEYGYQPELLEAVESVNARQKQVLVHRLHAHFGEDLGGRTFG
LWGLAFKPNTDDMREAPSRVVMEALWEAGARVQAYDPEAMDEAERIYGNRQDLELCDNLYDAVEDADALIVCTEWQVFRS
PDFERIRDALRQPVVFDGRNVYPPSMMEALGFTYYGMGRGESIRRPL

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=470, Percent_Identity=33.1914893617021, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI296040438, Length=372, Percent_Identity=33.8709677419355, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI296040443, Length=316, Percent_Identity=33.5443037974684, Blast_Score=172, Evalue=4e-43,
Organism=Escherichia coli, GI1788340, Length=359, Percent_Identity=29.8050139275766, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI48994968, Length=437, Percent_Identity=27.0022883295195, Blast_Score=138, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17560350, Length=463, Percent_Identity=32.3974082073434, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI17136908, Length=467, Percent_Identity=33.1905781584582, Blast_Score=245, Evalue=4e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49561; Mature: 49561

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTIFGSGYVGLVTGTCFADAGNDVVCVDIDAERVAQLQRGEVPIYEPGLDEMLSFNQE
CEEEEEECCCEEEEEEEEEECCCCCEEEEECCHHHHHHHHHCCCCCCCCCHHHHHCCCCC
EGRLRFTTNAAEGVHHGLFQFIAVGTPSDEDGSADLQHVLAVARTIGQHMDDYRVVVDKS
CCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
TVPVGTADRVRAAVGEELAARGEQLEYDVVSNPEFLKEGAAIDDFVKPDRIIIGSDNPRT
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCHHHHCCCCEEEECCCCCCH
GELMKALYAPFNRSHDRLIAMDVRSAELTKYASNAMLATKISFMNELSNLAERLGADIEQ
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHH
VRVGMGSDPRIGYHFIYPGCGYGGSCFPKDVKALTHTAHEYGYQPELLEAVESVNARQKQ
HHCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHH
VLVHRLHAHFGEDLGGRTFGLWGLAFKPNTDDMREAPSRVVMEALWEAGARVQAYDPEAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHH
DEAERIYGNRQDLELCDNLYDAVEDADALIVCTEWQVFRSPDFERIRDALRQPVVFDGRN
HHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHCCEEECCCC
VYPPSMMEALGFTYYGMGRGESIRRPL
CCCHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MKVTIFGSGYVGLVTGTCFADAGNDVVCVDIDAERVAQLQRGEVPIYEPGLDEMLSFNQE
CEEEEEECCCEEEEEEEEEECCCCCEEEEECCHHHHHHHHHCCCCCCCCCHHHHHCCCCC
EGRLRFTTNAAEGVHHGLFQFIAVGTPSDEDGSADLQHVLAVARTIGQHMDDYRVVVDKS
CCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
TVPVGTADRVRAAVGEELAARGEQLEYDVVSNPEFLKEGAAIDDFVKPDRIIIGSDNPRT
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCHHHHCCCCEEEECCCCCCH
GELMKALYAPFNRSHDRLIAMDVRSAELTKYASNAMLATKISFMNELSNLAERLGADIEQ
HHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHH
VRVGMGSDPRIGYHFIYPGCGYGGSCFPKDVKALTHTAHEYGYQPELLEAVESVNARQKQ
HHCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHH
VLVHRLHAHFGEDLGGRTFGLWGLAFKPNTDDMREAPSRVVMEALWEAGARVQAYDPEAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHH
DEAERIYGNRQDLELCDNLYDAVEDADALIVCTEWQVFRSPDFERIRDALRQPVVFDGRN
HHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHCCEEECCCC
VYPPSMMEALGFTYYGMGRGESIRRPL
CCCHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]