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The map label for this gene is cheA [H]

Identifier: 121998946

GI number: 121998946

Start: 2379876

End: 2381987

Strand: Reverse

Name: cheA [H]

Synonym: Hhal_2167

Alternate gene names: 121998946

Gene position: 2381987-2379876 (Counterclockwise)

Preceding gene: 121998947

Following gene: 121998945

Centisome position: 88.93

GC content: 66.76

Gene sequence:

>2112_bases
ATGAGCGTAGACCTGAGCCAGTTCCTGCAGACCTTCTTCGAGGAGAGCTTCGAGGGGCTGGATACCATGGAGTCGGGCCT
GCTGGAACTCGATCCAGAGAGCCCGGATCCCGAGGCCCTCAACAACGTCTTCCGCGCGGCCCACTCCATCAAGGGGGGCG
CCGGAACCTTCGGTCTCAGCGCGGTCTCGGACTTCACCCACCGCATGGAGACCCTGCTCGATCGACTGCGTGACGGCAAA
CAGGCGGTTACGCCCGACTGCGTCAATGTGTTGCTGAATGCCGTCGATTGCCTGCGAGGCATGCTGGTGGCGATCCAGAG
TGACCAAACCCTGGACGCCGACGCGATCAGCACTGCCCAGCAGCGGCTCGACGAGCAGCTCGGGCAGGCACCCGTGGGCG
GTGGGGGGGCGACCGGCGCCGCGGCCGGACCGACAGCCGGCGGCGGTGATGCCGGCGGTGACGATGCGCCGCCGCCCCGC
GGGGGAGGCGGCGGCGGCGGCTGGTTGATTCGCTTCGAGCCGCAGCCCCACCTGTTCGCCACGGGCAACGACCCGCGTCG
GCTCTTCTTGGCCCTCCAGGATCTCGGCGAGCTTGAGGTCGAATGCGACACCTCGGGTTTGCCGCCCTTCGAGCAGCTCG
ATCCGGAAACCTGTCAGCTGGCTTGGACCCTGCGCCTCTACGCCGACGTGCCCGAGGCGGCGGTGCGCGAGGTCTTCGAG
TGGGTCGAGGACGATGCCCGGCTCGAGATCCAGCCCCTGGAGGCCGCAGGTACCGAGGAGGTAGCTCCGGTAGCACCCGG
GCAGCCCCCGATGCCGACCTCTGAGGAGAGTGGCCCTGCGGCGCCCGCAGCCGGCGGTGGCGAAGCGCGCAAGCCGGCCG
CACGCCGTGGGGGAGGGAATAGCTCCATCCGGGTGGATACCGAGAAGATCGACGCCCTCATCGATATGGTCGGTGAGCTG
GTGATCACCCAGTCGATGCTCAGCCAGGTCGGCAAGGAGTTCACCGCCGAGCGCCTGGAAGAACTCCAGGACGGCCTGGC
GCAGCTCGAGCGCAACACGCGCGAACTGCAAGAGAACGTCATGCGCATCCGCATGGTGCCAATCAGCTTCGCCTACTCGC
GGCTGCCGCGCATCGTCCACGACACCAGCCGCGCCCTGGGCAAGGCCGTCGACTTCCAGATGGAGGGCGAGCAGACCGAG
CTGGACAAGACGGTGATGGAGAAGATCATCGATCCGCTGGTCCATCTGGTCCGCAACAGCGTCGACCACGGCATCGAGCC
GCCGGAGGAGCGGGCCGCTGCCGGCAAGCCCGAGACCGGCACCATCACCATCGAGGCCTACCACAAGGGCGGCAATATCA
TCATCGAGATCGCCGATGATGGTCGCGGCATCAATCGCGACAAGCTGCTGGCCAAGGCGCGCAGCTCCGGGCTGCTCGAG
GACGGCACCGAACTGCCCGATGACCAGGTCTTCGACCTGATCTTCCATCCCGGGCTCTCCACTCATGAGCAGGCCACCGA
ATACTCCGGCCGGGGTGTGGGGATGGATGTGGTCAAGCGCAACGTCCGCTCCCTGTCCGGCAATATCCATGTGCGCTCAG
CTCAAGGGCAGGGCACGACCATCACCATCTCGCTGCCGCTGACCCTCTCGATCCTGGACGGCCAGCTGTTCCGGGTAGGC
GACCAGACCTACATCGTGCCGCTGGTTTCGGTCATCGAGTCGCTCCAAGTCGACGGCAGCAAGCTCAGCCGGGTTACCGG
CCGGGGCGAGGTCTACCACTGGCGCGAGGGGTACGTCCCCATCGTGCGCCTCCACGAGCTCTTCGACACCGAACCGGTTC
GCCGCGAGCTCGCCGGTGGGCTGATGGTGATCGTCGAGGACGAAGACACCTACCTGGGAGTCTTTGTCGACGACCTCCTT
GATCAGCAGCAGGTGGTCATCAAGAGCCTGGAGGCCAACTACCTGCAGGTGCCCGGCATCGCTGGCGCCACCATCCTCGG
CGACGGCACCGTGGCCCTGATCCTCGATATCGCCGGGCTCATCGAGATGAGCCGCGGTGGCCGTCGTCAGCCCTACATCC
CCACCCCGGAGGACAGCGATGAGGCCGCCTGA

Upstream 100 bases:

>100_bases
TGGTTGGTCAAGCCCTTCGACCCGGATCAGCTGGTCAACACCATCAAGAAGGTGGTGCGCTGACGGCCCGGGCCCTGAGC
GCCCAACGGGGGGGCGAGCG

Downstream 100 bases:

>100_bases
AGCATCCATCCCCGGGATCCCCCAGTTGCGAAGCGGAGAGCAGTCATGACCCAGGACAGCGAGCACGGCACCCTCGGAGA
CGACCGCAAGGCAGCCGCAC

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 703; Mature: 702

Protein sequence:

>703_residues
MSVDLSQFLQTFFEESFEGLDTMESGLLELDPESPDPEALNNVFRAAHSIKGGAGTFGLSAVSDFTHRMETLLDRLRDGK
QAVTPDCVNVLLNAVDCLRGMLVAIQSDQTLDADAISTAQQRLDEQLGQAPVGGGGATGAAAGPTAGGGDAGGDDAPPPR
GGGGGGGWLIRFEPQPHLFATGNDPRRLFLALQDLGELEVECDTSGLPPFEQLDPETCQLAWTLRLYADVPEAAVREVFE
WVEDDARLEIQPLEAAGTEEVAPVAPGQPPMPTSEESGPAAPAAGGGEARKPAARRGGGNSSIRVDTEKIDALIDMVGEL
VITQSMLSQVGKEFTAERLEELQDGLAQLERNTRELQENVMRIRMVPISFAYSRLPRIVHDTSRALGKAVDFQMEGEQTE
LDKTVMEKIIDPLVHLVRNSVDHGIEPPEERAAAGKPETGTITIEAYHKGGNIIIEIADDGRGINRDKLLAKARSSGLLE
DGTELPDDQVFDLIFHPGLSTHEQATEYSGRGVGMDVVKRNVRSLSGNIHVRSAQGQGTTITISLPLTLSILDGQLFRVG
DQTYIVPLVSVIESLQVDGSKLSRVTGRGEVYHWREGYVPIVRLHELFDTEPVRRELAGGLMVIVEDEDTYLGVFVDDLL
DQQQVVIKSLEANYLQVPGIAGATILGDGTVALILDIAGLIEMSRGGRRQPYIPTPEDSDEAA

Sequences:

>Translated_703_residues
MSVDLSQFLQTFFEESFEGLDTMESGLLELDPESPDPEALNNVFRAAHSIKGGAGTFGLSAVSDFTHRMETLLDRLRDGK
QAVTPDCVNVLLNAVDCLRGMLVAIQSDQTLDADAISTAQQRLDEQLGQAPVGGGGATGAAAGPTAGGGDAGGDDAPPPR
GGGGGGGWLIRFEPQPHLFATGNDPRRLFLALQDLGELEVECDTSGLPPFEQLDPETCQLAWTLRLYADVPEAAVREVFE
WVEDDARLEIQPLEAAGTEEVAPVAPGQPPMPTSEESGPAAPAAGGGEARKPAARRGGGNSSIRVDTEKIDALIDMVGEL
VITQSMLSQVGKEFTAERLEELQDGLAQLERNTRELQENVMRIRMVPISFAYSRLPRIVHDTSRALGKAVDFQMEGEQTE
LDKTVMEKIIDPLVHLVRNSVDHGIEPPEERAAAGKPETGTITIEAYHKGGNIIIEIADDGRGINRDKLLAKARSSGLLE
DGTELPDDQVFDLIFHPGLSTHEQATEYSGRGVGMDVVKRNVRSLSGNIHVRSAQGQGTTITISLPLTLSILDGQLFRVG
DQTYIVPLVSVIESLQVDGSKLSRVTGRGEVYHWREGYVPIVRLHELFDTEPVRRELAGGLMVIVEDEDTYLGVFVDDLL
DQQQVVIKSLEANYLQVPGIAGATILGDGTVALILDIAGLIEMSRGGRRQPYIPTPEDSDEAA
>Mature_702_residues
SVDLSQFLQTFFEESFEGLDTMESGLLELDPESPDPEALNNVFRAAHSIKGGAGTFGLSAVSDFTHRMETLLDRLRDGKQ
AVTPDCVNVLLNAVDCLRGMLVAIQSDQTLDADAISTAQQRLDEQLGQAPVGGGGATGAAAGPTAGGGDAGGDDAPPPRG
GGGGGGWLIRFEPQPHLFATGNDPRRLFLALQDLGELEVECDTSGLPPFEQLDPETCQLAWTLRLYADVPEAAVREVFEW
VEDDARLEIQPLEAAGTEEVAPVAPGQPPMPTSEESGPAAPAAGGGEARKPAARRGGGNSSIRVDTEKIDALIDMVGELV
ITQSMLSQVGKEFTAERLEELQDGLAQLERNTRELQENVMRIRMVPISFAYSRLPRIVHDTSRALGKAVDFQMEGEQTEL
DKTVMEKIIDPLVHLVRNSVDHGIEPPEERAAAGKPETGTITIEAYHKGGNIIIEIADDGRGINRDKLLAKARSSGLLED
GTELPDDQVFDLIFHPGLSTHEQATEYSGRGVGMDVVKRNVRSLSGNIHVRSAQGQGTTITISLPLTLSILDGQLFRVGD
QTYIVPLVSVIESLQVDGSKLSRVTGRGEVYHWREGYVPIVRLHELFDTEPVRRELAGGLMVIVEDEDTYLGVFVDDLLD
QQQVVIKSLEANYLQVPGIAGATILGDGTVALILDIAGLIEMSRGGRRQPYIPTPEDSDEAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=689, Percent_Identity=41.944847605225, Blast_Score=488, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75636; Mature: 75505

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDLSQFLQTFFEESFEGLDTMESGLLELDPESPDPEALNNVFRAAHSIKGGAGTFGLS
CCCCHHHHHHHHHHHHHCCHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
AVSDFTHRMETLLDRLRDGKQAVTPDCVNVLLNAVDCLRGMLVAIQSDQTLDADAISTAQ
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHH
QRLDEQLGQAPVGGGGATGAAAGPTAGGGDAGGDDAPPPRGGGGGGGWLIRFEPQPHLFA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEE
TGNDPRRLFLALQDLGELEVECDTSGLPPFEQLDPETCQLAWTLRLYADVPEAAVREVFE
CCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCEEEEEEEEEECCCCHHHHHHHHH
WVEDDARLEIQPLEAAGTEEVAPVAPGQPPMPTSEESGPAAPAAGGGEARKPAARRGGGN
HHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCC
SSIRVDTEKIDALIDMVGELVITQSMLSQVGKEFTAERLEELQDGLAQLERNTRELQENV
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRIRMVPISFAYSRLPRIVHDTSRALGKAVDFQMEGEQTELDKTVMEKIIDPLVHLVRNS
HEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHH
VDHGIEPPEERAAAGKPETGTITIEAYHKGGNIIIEIADDGRGINRDKLLAKARSSGLLE
HHCCCCCCHHHHCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCCC
DGTELPDDQVFDLIFHPGLSTHEQATEYSGRGVGMDVVKRNVRSLSGNIHVRSAQGQGTT
CCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCE
ITISLPLTLSILDGQLFRVGDQTYIVPLVSVIESLQVDGSKLSRVTGRGEVYHWREGYVP
EEEEECEEEEEECCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEECCCCCH
IVRLHELFDTEPVRRELAGGLMVIVEDEDTYLGVFVDDLLDQQQVVIKSLEANYLQVPGI
HHHHHHHHCCCHHHHHHCCCEEEEEECCCCEEEEEHHHHHCHHHHHHHHHCCCEEECCCC
AGATILGDGTVALILDIAGLIEMSRGGRRQPYIPTPEDSDEAA
CCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVDLSQFLQTFFEESFEGLDTMESGLLELDPESPDPEALNNVFRAAHSIKGGAGTFGLS
CCCHHHHHHHHHHHHHCCHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
AVSDFTHRMETLLDRLRDGKQAVTPDCVNVLLNAVDCLRGMLVAIQSDQTLDADAISTAQ
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHH
QRLDEQLGQAPVGGGGATGAAAGPTAGGGDAGGDDAPPPRGGGGGGGWLIRFEPQPHLFA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEE
TGNDPRRLFLALQDLGELEVECDTSGLPPFEQLDPETCQLAWTLRLYADVPEAAVREVFE
CCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCEEEEEEEEEECCCCHHHHHHHHH
WVEDDARLEIQPLEAAGTEEVAPVAPGQPPMPTSEESGPAAPAAGGGEARKPAARRGGGN
HHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCC
SSIRVDTEKIDALIDMVGELVITQSMLSQVGKEFTAERLEELQDGLAQLERNTRELQENV
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRIRMVPISFAYSRLPRIVHDTSRALGKAVDFQMEGEQTELDKTVMEKIIDPLVHLVRNS
HEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHH
VDHGIEPPEERAAAGKPETGTITIEAYHKGGNIIIEIADDGRGINRDKLLAKARSSGLLE
HHCCCCCCHHHHCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCCC
DGTELPDDQVFDLIFHPGLSTHEQATEYSGRGVGMDVVKRNVRSLSGNIHVRSAQGQGTT
CCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCE
ITISLPLTLSILDGQLFRVGDQTYIVPLVSVIESLQVDGSKLSRVTGRGEVYHWREGYVP
EEEEECEEEEEECCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEECCCCCH
IVRLHELFDTEPVRRELAGGLMVIVEDEDTYLGVFVDDLLDQQQVVIKSLEANYLQVPGI
HHHHHHHHCCCHHHHHHCCCEEEEEECCCCEEEEEHHHHHCHHHHHHHHHCCCEEECCCC
AGATILGDGTVALILDIAGLIEMSRGGRRQPYIPTPEDSDEAA
CCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2002011; 9097040; 9278503; 3510184; 2832069; 2068106; 8555213; 8639521; 9020767; 9437425; 9636149 [H]