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The map label for this gene is htr4 [H]

Identifier: 121998944

GI number: 121998944

Start: 2377808

End: 2379220

Strand: Reverse

Name: htr4 [H]

Synonym: Hhal_2165

Alternate gene names: 121998944

Gene position: 2379220-2377808 (Counterclockwise)

Preceding gene: 121998945

Following gene: 121998943

Centisome position: 88.83

GC content: 68.01

Gene sequence:

>1413_bases
ATGAATGACACCAATACCGCGCTTTCCGCCGAAGAGCGCACCGCCCTGATCGAGGAGGGCTGGGTGCCGCCGGAGCGTGT
ACGAGAACTGCTCGGCACCATCGATCAGATCGGCCGCGGCGATTACCTCGGCGTGCCGCGCGGCGATTGCGAACTCTCCA
GGGCCCTGCGGCGGCTGGCCGGCCAGGTCGGACGGAAAGACTCGCGCGCGCTGCACGACATCGTCGAGCTGGCCGCGCAC
ACCGCCGACAGCCTGGTGGCGACCTCGGGGATGCGCATGACCATTCGCGAGACCAGCGAGCGCAGTCAGACCATCGCTTC
CACCTCCGAGGAACTGGCCGCCAGTGTCGACACCGTGGCCGACAACAGCGCTGCGGTGGCCACCGAGACCGAGCGCGTGC
AGGAGTTGGTGGATGCCGGTGACAAGGCCTCGCGGACCACCGACGAAACGGTCCGGGAGATCGCCGGACTGGCCGAGACG
GCGGCCACGCGCGTCAAACAGCTCAACCAGGCTTCCAACGAGATCGGCTCGATTATCGAGCTCATCGAAGAGATTGCCTT
CCAGACCAATATGCTGGCCCTCAACGCCTCGGTGGAGGCGGCCCGGGCCGGGCAGGCCGGCGCCGGTTTCTCGGTAGTTG
CCCAGGAGGTGCGCCGCCTGGCCGATCAGACGAAGAGCGCCACCGTAGATATCGCCCAACGGATCCGGACCCTGCGCGAC
GAGACCGAGGCCATCTCCGCCTCGGTTGAAGAGATGGGCAGCGCCGTCGACCGGGGACGCGAGGCCACCGCCGAGACCAC
GCAGACCATGCAGCAGGTGGCCGAGCGCATGCGCGGGGTGACCGAGCACATCCAGAACGTCTCCTCGGTGATCAATGAGC
AGAAGGGCGCGGTGACCCAGGTGGCCGAGTCCATCAGCGCCGTGACCGACCGCACCGAGCGCAACGTCAACGACGTGGAG
GGCACCCTCGACGCCCTGGGCCGCTCCACGGCGATCCTCACCGATCAGATCGAGCGGCTGGGCGAGCACAATCTGCCCAA
GCTCTTCATTGAGCGCAGCAAGTTCGACCACGTGATGTGGAAGCGGCGCATCGCCGCCATGCTGGCCGGTCGCGAGGATG
TCGACAGCCGCGAGCTGACCGACCACCACGCCTGTCGTCTCGGCAAGTGGTACGACGCGGTCGAGGAGGCCTGGATCCGT
CAGCTGCCGGCCTTCATCGAGCTGGAGGAGCCGCACCGGGCGGTCCACGCCCACGGCAAGCGCGCCGCCGAGCTCTACAA
CCAGGGCGAGGTCGACGCCGCTGCCGGCGAGCTGGAGCAGCTCGGGGACAACTCCGAGCAGGTGGTCGAGCTGCTGAGCC
GCCTGGCCCGCGAGATGGATGAGGGCAACAAGAACGGGGCGAGCGGGGCATGA

Upstream 100 bases:

>100_bases
GACGTCGATGAGCTGCTCAGCGACGAGGATCTCGCCATCGCCGATGATCAGAGCCGCATCGCCGAGGTGGTCCGCTCGGC
CGGGCAGGAGGGTACCCCCG

Downstream 100 bases:

>100_bases
GCGCAGCAGGCCCCCGCGTCGTCTCCTTCCTGAACCAGAAAGGCGGGGTGGGCAAGACCACTTCGGCGGTGAGTGTCGCC
CACGCCTGGGCGCGCTCCGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: HTP VI [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MNDTNTALSAEERTALIEEGWVPPERVRELLGTIDQIGRGDYLGVPRGDCELSRALRRLAGQVGRKDSRALHDIVELAAH
TADSLVATSGMRMTIRETSERSQTIASTSEELAASVDTVADNSAAVATETERVQELVDAGDKASRTTDETVREIAGLAET
AATRVKQLNQASNEIGSIIELIEEIAFQTNMLALNASVEAARAGQAGAGFSVVAQEVRRLADQTKSATVDIAQRIRTLRD
ETEAISASVEEMGSAVDRGREATAETTQTMQQVAERMRGVTEHIQNVSSVINEQKGAVTQVAESISAVTDRTERNVNDVE
GTLDALGRSTAILTDQIERLGEHNLPKLFIERSKFDHVMWKRRIAAMLAGREDVDSRELTDHHACRLGKWYDAVEEAWIR
QLPAFIELEEPHRAVHAHGKRAAELYNQGEVDAAAGELEQLGDNSEQVVELLSRLAREMDEGNKNGASGA

Sequences:

>Translated_470_residues
MNDTNTALSAEERTALIEEGWVPPERVRELLGTIDQIGRGDYLGVPRGDCELSRALRRLAGQVGRKDSRALHDIVELAAH
TADSLVATSGMRMTIRETSERSQTIASTSEELAASVDTVADNSAAVATETERVQELVDAGDKASRTTDETVREIAGLAET
AATRVKQLNQASNEIGSIIELIEEIAFQTNMLALNASVEAARAGQAGAGFSVVAQEVRRLADQTKSATVDIAQRIRTLRD
ETEAISASVEEMGSAVDRGREATAETTQTMQQVAERMRGVTEHIQNVSSVINEQKGAVTQVAESISAVTDRTERNVNDVE
GTLDALGRSTAILTDQIERLGEHNLPKLFIERSKFDHVMWKRRIAAMLAGREDVDSRELTDHHACRLGKWYDAVEEAWIR
QLPAFIELEEPHRAVHAHGKRAAELYNQGEVDAAAGELEQLGDNSEQVVELLSRLAREMDEGNKNGASGA
>Mature_470_residues
MNDTNTALSAEERTALIEEGWVPPERVRELLGTIDQIGRGDYLGVPRGDCELSRALRRLAGQVGRKDSRALHDIVELAAH
TADSLVATSGMRMTIRETSERSQTIASTSEELAASVDTVADNSAAVATETERVQELVDAGDKASRTTDETVREIAGLAET
AATRVKQLNQASNEIGSIIELIEEIAFQTNMLALNASVEAARAGQAGAGFSVVAQEVRRLADQTKSATVDIAQRIRTLRD
ETEAISASVEEMGSAVDRGREATAETTQTMQQVAERMRGVTEHIQNVSSVINEQKGAVTQVAESISAVTDRTERNVNDVE
GTLDALGRSTAILTDQIERLGEHNLPKLFIERSKFDHVMWKRRIAAMLAGREDVDSRELTDHHACRLGKWYDAVEEAWIR
QLPAFIELEEPHRAVHAHGKRAAELYNQGEVDAAAGELEQLGDNSEQVVELLSRLAREMDEGNKNGASGA

Specific function: Potentially involved in chemo- or phototactic signal transduction [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=219, Percent_Identity=34.703196347032, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788194, Length=307, Percent_Identity=30.6188925081433, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788195, Length=227, Percent_Identity=32.5991189427313, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789453, Length=225, Percent_Identity=31.1111111111111, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI2367378, Length=306, Percent_Identity=28.7581699346405, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 51210; Mature: 51210

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTNTALSAEERTALIEEGWVPPERVRELLGTIDQIGRGDYLGVPRGDCELSRALRRLA
CCCCCCHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
GQVGRKDSRALHDIVELAAHTADSLVATSGMRMTIRETSERSQTIASTSEELAASVDTVA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
DNSAAVATETERVQELVDAGDKASRTTDETVREIAGLAETAATRVKQLNQASNEIGSIIE
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIEEIAFQTNMLALNASVEAARAGQAGAGFSVVAQEVRRLADQTKSATVDIAQRIRTLRD
HHHHHHHHHHHHEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETEAISASVEEMGSAVDRGREATAETTQTMQQVAERMRGVTEHIQNVSSVINEQKGAVTQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VAESISAVTDRTERNVNDVEGTLDALGRSTAILTDQIERLGEHNLPKLFIERSKFDHVMW
HHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
KRRIAAMLAGREDVDSRELTDHHACRLGKWYDAVEEAWIRQLPAFIELEEPHRAVHAHGK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHHCCH
RAAELYNQGEVDAAAGELEQLGDNSEQVVELLSRLAREMDEGNKNGASGA
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNDTNTALSAEERTALIEEGWVPPERVRELLGTIDQIGRGDYLGVPRGDCELSRALRRLA
CCCCCCHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
GQVGRKDSRALHDIVELAAHTADSLVATSGMRMTIRETSERSQTIASTSEELAASVDTVA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
DNSAAVATETERVQELVDAGDKASRTTDETVREIAGLAETAATRVKQLNQASNEIGSIIE
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIEEIAFQTNMLALNASVEAARAGQAGAGFSVVAQEVRRLADQTKSATVDIAQRIRTLRD
HHHHHHHHHHHHEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETEAISASVEEMGSAVDRGREATAETTQTMQQVAERMRGVTEHIQNVSSVINEQKGAVTQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VAESISAVTDRTERNVNDVEGTLDALGRSTAILTDQIERLGEHNLPKLFIERSKFDHVMW
HHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
KRRIAAMLAGREDVDSRELTDHHACRLGKWYDAVEEAWIRQLPAFIELEEPHRAVHAHGK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHHCCH
RAAELYNQGEVDAAAGELEQLGDNSEQVVELLSRLAREMDEGNKNGASGA
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8674984; 11016950 [H]