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The map label for this gene is rlmH

Identifier: 121998918

GI number: 121998918

Start: 2340964

End: 2341428

Strand: Reverse

Name: rlmH

Synonym: Hhal_2139

Alternate gene names: 121998918

Gene position: 2341428-2340964 (Counterclockwise)

Preceding gene: 121998919

Following gene: 121998917

Centisome position: 87.42

GC content: 72.47

Gene sequence:

>465_bases
GTGCGCATCCACCTCGTCGCAGTAGGCCACAAACCGCCGCGCTGGGTGCGCGACGGTCACGAGACCTACGCCCAGCGCCT
GGGCAAGGGGTGGCGGCTGGAGCTGCACGAGGTTGGCGCCGGCGGGCGCGGGAATGACGACCCACAGGCCCGTGAGCGCG
AGGGCGAGCGCCTGCTGCGCGCGTTGCCCTCGCGGGCGGTCTGTGTGGCCCTGGACGAGGGCGGCACGCCGCGGGACACC
CGGCAGTGGGCCCGCAGCCTGGAGCGCTGGAGCCATGAGGGCGGCGAGGTCGCGTTCATCATCGGCGGGGCCGACGGGCT
GAGCGATGCGGTGCGCCAGCGCGCCGACGCCTGCTGGTCGCTGTCGCCACTGACGTTACCGCACATGCTGGTGCGGGTGC
TGGTGGCCGAGCAGGTCTATCGTGCCTGGACGCTGCTCAGCGGCCATCCGTATCATCGATCGTGA

Upstream 100 bases:

>100_bases
AGTGGGTGCTGATCGATCTGGGCGATGCCGTGGTGCACGTCATGACCCAAGAGAGCCGCGACTTCTACCGGCTCGAGCGC
ATGTGGGAGATGGACGAGGC

Downstream 100 bases:

>100_bases
CGCACCGCCACAAGGTCTAGGGAAATGGAGCCTTACATCATTCTCGCATCCGGGTCGCCCCGCCGACGCGAGCTGCTCGA
GCGCATCGGCATCGGTTATC

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MRIHLVAVGHKPPRWVRDGHETYAQRLGKGWRLELHEVGAGGRGNDDPQAREREGERLLRALPSRAVCVALDEGGTPRDT
RQWARSLERWSHEGGEVAFIIGGADGLSDAVRQRADACWSLSPLTLPHMLVRVLVAEQVYRAWTLLSGHPYHRS

Sequences:

>Translated_154_residues
MRIHLVAVGHKPPRWVRDGHETYAQRLGKGWRLELHEVGAGGRGNDDPQAREREGERLLRALPSRAVCVALDEGGTPRDT
RQWARSLERWSHEGGEVAFIIGGADGLSDAVRQRADACWSLSPLTLPHMLVRVLVAEQVYRAWTLLSGHPYHRS
>Mature_154_residues
MRIHLVAVGHKPPRWVRDGHETYAQRLGKGWRLELHEVGAGGRGNDDPQAREREGERLLRALPSRAVCVALDEGGTPRDT
RQWARSLERWSHEGGEVAFIIGGADGLSDAVRQRADACWSLSPLTLPHMLVRVLVAEQVYRAWTLLSGHPYHRS

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=155, Percent_Identity=49.0322580645161, Blast_Score=139, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_HALHL (A1WYZ1)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003705.1
- ProteinModelPortal:   A1WYZ1
- SMR:   A1WYZ1
- STRING:   A1WYZ1
- GeneID:   4711222
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2139
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- PhylomeDB:   A1WYZ1
- BioCyc:   HHAL349124:HHAL_2139-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR016051
- InterPro:   IPR003742
- PIRSF:   PIRSF004505
- TIGRFAMs:   TIGR00246

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 17282; Mature: 17282

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIHLVAVGHKPPRWVRDGHETYAQRLGKGWRLELHEVGAGGRGNDDPQAREREGERLLR
CEEEEEEECCCCCHHHCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
ALPSRAVCVALDEGGTPRDTRQWARSLERWSHEGGEVAFIIGGADGLSDAVRQRADACWS
HCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
LSPLTLPHMLVRVLVAEQVYRAWTLLSGHPYHRS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRIHLVAVGHKPPRWVRDGHETYAQRLGKGWRLELHEVGAGGRGNDDPQAREREGERLLR
CEEEEEEECCCCCHHHCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
ALPSRAVCVALDEGGTPRDTRQWARSLERWSHEGGEVAFIIGGADGLSDAVRQRADACWS
HCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
LSPLTLPHMLVRVLVAEQVYRAWTLLSGHPYHRS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA