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The map label for this gene is cyaA [H]

Identifier: 121998668

GI number: 121998668

Start: 2074161

End: 2076098

Strand: Reverse

Name: cyaA [H]

Synonym: Hhal_1889

Alternate gene names: 121998668

Gene position: 2076098-2074161 (Counterclockwise)

Preceding gene: 121998669

Following gene: 121998667

Centisome position: 77.51

GC content: 68.94

Gene sequence:

>1938_bases
GTGGCTCAGCCGGCGCGGCGTCGGGCGGTCGGTGTCGGACTGGTGGTCCTGGCGGCCACCGTCGCCGGTGTGCTCCATAC
CGTCGGCTGGCTGGTTCCCGTTGAGCGGGTCGTCTACGACCAGCGGACACAGTGGTTGCACGGGGATGCGCACGCCCCGG
AGGAGATCGTTATCCTCTATGTGGACGAGTACAGCATCCGCGCCATGGAGCCGGCGGTGGGGCGCTGGCCCTGGCCCCGC
TCGCTCTGGGCGGACCTCCTGGAATTCCTCGCGCATGGGCGCCCGGCGGCGGTGGTCTTCGACGTTCTCTTCACCGAGTC
GGCCCGGGAGGATGGGGGGGCCGGGGATGCCGCCTTCGCCCAGGCAAGCGCGGCGCTGGGAGGCGTGGTTCACGCCATGC
AGTTCTTGGAGGCCAATCCGCGGGAGGACCGGTCTGCAGACCCCTTGCCGAAGGGAATGGCCGATCGCTACGCGCTGGGG
GACACCCAAGGGTGGCCGGATCCGCGCTTTCAGGAGCACGGCGTACCGGTGGCACCCCTGGCCGACAAGGCCGAGCAGCT
CGGGGTGGTGACAACGGGACCGGATCGCGACGGAGTGCACCGCCGCCTCCCTCCACTGCTGCCCTACGACGGCGAAATCT
ACCCGGCGCTCGGTGTCGCGGCGCTGCTCGCAGCGGGGCAGGATTCGTCCACCATCGATTGGGACGAGCAGGGGGTGCAG
TGGGCAGATCAGACGCTGGCTACCGACGCGTCGGGCCAGGCCCTGGTCAATCCGTACGCGGAGTTCGATAGCTACCCCGT
TGTCGAGCTCTTCGAGGCGCAACGCCAGATCCGCCGCGGTGAGCTGGCGGACCTGCGGGTGGACCCCGAGGTCTTCAACG
ACCGGATCGTCTTCGTCGGGGCCAGCGCCGCAGCCCTCCACGACCTCAAGGCGACCCCCTTGTCGGGGCGCACTCCCGGC
GTGGAGCTGCACGCCTCTCTGATCGGCAATCTCCTGGATGGCCAGACGCTGCGGTTCGGCCCCGGCACCATCGAGGCGGT
ATTGGTGCCTGCGGCGGCCGGGGCAGTCGGCCTGGCTGTCCTGCTGGTGCCGGCACTGAGCGCTCGTGTACTCCTGCCGC
TGGCCGTGGTGGCGGCGTGGACGGCCTGGGTCCTCGTTCAGCATGCGGCCGGGATCGTCTGGTCGTGGCTGCCGCTCGTG
GTCGGCGTGCTCCTGGCCTGGGTCACCGTGCTCGTCTTTCTCGGCTTCACGGAAGGGCGCGATCGTCGCCGGGTCCGGCA
GCTGCTGGCGCAGTACGTCTCACCGGCAGTCCTTCAGGAGGTGGTCGATCGCCGCGGTGAAGTCGCCACCGGAGAGGTGG
GCAGCACCGAGCAGGTGACGCTGCTCTTCTCCGATATCCGGGGGTTTACGAGCCTGTCGGAGGGGCAGGAGGCGGCGTCG
GTCGTGGAGTTGCTGAACATCCACCTCGGGGAGATGAGCGAGGCCATCTTCGAGCACGATGGGACCCTCGATAAGTTCAT
CGGCGACGCGGTCATGGCCTTCTGGGGGGCGCCGGTCCGGGTCCGCGATCACGCGGACCGGGCGGTACGCGCGGCACTGG
CCATGACGCAGCGCCTGGAAGGAGTCAACGAGGCCGTGGTCGCCCGCGGTGGTAAACCGCTTGCGATCGGCATCGGCCTC
CATACCGGTGAGGTCGTGCTCGGCAATATCGGCTCGGTCCGCAAGCTGGACTACACGGTGATCGGCGACAACGTGAACGT
CGCCTCCCGCCTGGAAGACCTGACCAAGGCCTACGGCTGCTCGGTGCTGATCAGCGGCGATACCTACGCGGATCTGCCGC
AGGGGTGGCAGTGCCGGTACGTGGATCGGGTCCAGGTCCGGGGGCGGCAGCGCATGCTTGATCTCTATGAACCCATCGCG
CCACCGGAGGGAGCATGA

Upstream 100 bases:

>100_bases
GGGAGACATGGACGACGGCCTCGATTTCGAATCGGATGAAGACGGCGACGAGGAAGAGGAAGGCGAAGACGAGTAAGGGG
AATCCCGGAGGCTAAGGCGA

Downstream 100 bases:

>100_bases
GGCGATCACAGTGGCACTGGCTGATCCTCCCGCTCGGTCTGGTCCTCGCTTCCGCGGCGTCGGGGGAGGATTTGCTCTTC
GTCCAGAGTGAGCAGGGCGA

Product: putative adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MAQPARRRAVGVGLVVLAATVAGVLHTVGWLVPVERVVYDQRTQWLHGDAHAPEEIVILYVDEYSIRAMEPAVGRWPWPR
SLWADLLEFLAHGRPAAVVFDVLFTESAREDGGAGDAAFAQASAALGGVVHAMQFLEANPREDRSADPLPKGMADRYALG
DTQGWPDPRFQEHGVPVAPLADKAEQLGVVTTGPDRDGVHRRLPPLLPYDGEIYPALGVAALLAAGQDSSTIDWDEQGVQ
WADQTLATDASGQALVNPYAEFDSYPVVELFEAQRQIRRGELADLRVDPEVFNDRIVFVGASAAALHDLKATPLSGRTPG
VELHASLIGNLLDGQTLRFGPGTIEAVLVPAAAGAVGLAVLLVPALSARVLLPLAVVAAWTAWVLVQHAAGIVWSWLPLV
VGVLLAWVTVLVFLGFTEGRDRRRVRQLLAQYVSPAVLQEVVDRRGEVATGEVGSTEQVTLLFSDIRGFTSLSEGQEAAS
VVELLNIHLGEMSEAIFEHDGTLDKFIGDAVMAFWGAPVRVRDHADRAVRAALAMTQRLEGVNEAVVARGGKPLAIGIGL
HTGEVVLGNIGSVRKLDYTVIGDNVNVASRLEDLTKAYGCSVLISGDTYADLPQGWQCRYVDRVQVRGRQRMLDLYEPIA
PPEGA

Sequences:

>Translated_645_residues
MAQPARRRAVGVGLVVLAATVAGVLHTVGWLVPVERVVYDQRTQWLHGDAHAPEEIVILYVDEYSIRAMEPAVGRWPWPR
SLWADLLEFLAHGRPAAVVFDVLFTESAREDGGAGDAAFAQASAALGGVVHAMQFLEANPREDRSADPLPKGMADRYALG
DTQGWPDPRFQEHGVPVAPLADKAEQLGVVTTGPDRDGVHRRLPPLLPYDGEIYPALGVAALLAAGQDSSTIDWDEQGVQ
WADQTLATDASGQALVNPYAEFDSYPVVELFEAQRQIRRGELADLRVDPEVFNDRIVFVGASAAALHDLKATPLSGRTPG
VELHASLIGNLLDGQTLRFGPGTIEAVLVPAAAGAVGLAVLLVPALSARVLLPLAVVAAWTAWVLVQHAAGIVWSWLPLV
VGVLLAWVTVLVFLGFTEGRDRRRVRQLLAQYVSPAVLQEVVDRRGEVATGEVGSTEQVTLLFSDIRGFTSLSEGQEAAS
VVELLNIHLGEMSEAIFEHDGTLDKFIGDAVMAFWGAPVRVRDHADRAVRAALAMTQRLEGVNEAVVARGGKPLAIGIGL
HTGEVVLGNIGSVRKLDYTVIGDNVNVASRLEDLTKAYGCSVLISGDTYADLPQGWQCRYVDRVQVRGRQRMLDLYEPIA
PPEGA
>Mature_644_residues
AQPARRRAVGVGLVVLAATVAGVLHTVGWLVPVERVVYDQRTQWLHGDAHAPEEIVILYVDEYSIRAMEPAVGRWPWPRS
LWADLLEFLAHGRPAAVVFDVLFTESAREDGGAGDAAFAQASAALGGVVHAMQFLEANPREDRSADPLPKGMADRYALGD
TQGWPDPRFQEHGVPVAPLADKAEQLGVVTTGPDRDGVHRRLPPLLPYDGEIYPALGVAALLAAGQDSSTIDWDEQGVQW
ADQTLATDASGQALVNPYAEFDSYPVVELFEAQRQIRRGELADLRVDPEVFNDRIVFVGASAAALHDLKATPLSGRTPGV
ELHASLIGNLLDGQTLRFGPGTIEAVLVPAAAGAVGLAVLLVPALSARVLLPLAVVAAWTAWVLVQHAAGIVWSWLPLVV
GVLLAWVTVLVFLGFTEGRDRRRVRQLLAQYVSPAVLQEVVDRRGEVATGEVGSTEQVTLLFSDIRGFTSLSEGQEAASV
VELLNIHLGEMSEAIFEHDGTLDKFIGDAVMAFWGAPVRVRDHADRAVRAALAMTQRLEGVNEAVVARGGKPLAIGIGLH
TGEVVLGNIGSVRKLDYTVIGDNVNVASRLEDLTKAYGCSVLISGDTYADLPQGWQCRYVDRVQVRGRQRMLDLYEPIAP
PEGA

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

Organism=Homo sapiens, GI167830411, Length=215, Percent_Identity=32.5581395348837, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI134152694, Length=216, Percent_Identity=31.9444444444444, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI4504217, Length=215, Percent_Identity=32.5581395348837, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4580422, Length=213, Percent_Identity=31.4553990610329, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4557255, Length=159, Percent_Identity=30.8176100628931, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI115387102, Length=190, Percent_Identity=25.2631578947368, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4557257, Length=254, Percent_Identity=24.8031496062992, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI222080083, Length=173, Percent_Identity=32.9479768786127, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71989822, Length=218, Percent_Identity=32.1100917431193, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71989805, Length=218, Percent_Identity=32.1100917431193, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508769, Length=179, Percent_Identity=34.6368715083799, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71990146, Length=181, Percent_Identity=29.8342541436464, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17534659, Length=180, Percent_Identity=32.2222222222222, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193206632, Length=174, Percent_Identity=31.0344827586207, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI62484477, Length=211, Percent_Identity=29.8578199052133, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI62484298, Length=211, Percent_Identity=29.8578199052133, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI116008008, Length=211, Percent_Identity=30.3317535545024, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI161078020, Length=172, Percent_Identity=33.7209302325581, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651577, Length=161, Percent_Identity=33.5403726708075, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24667100, Length=135, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24647268, Length=172, Percent_Identity=30.2325581395349, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281366459, Length=140, Percent_Identity=37.1428571428571, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281366457, Length=140, Percent_Identity=37.1428571428571, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281366455, Length=140, Percent_Identity=37.1428571428571, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI56292422, Length=140, Percent_Identity=37.1428571428571, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI56292424, Length=140, Percent_Identity=37.1428571428571, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666940, Length=140, Percent_Identity=37.1428571428571, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24642014, Length=136, Percent_Identity=33.8235294117647, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI85725044, Length=217, Percent_Identity=29.4930875576037, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24585694, Length=141, Percent_Identity=29.0780141843972, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 69411; Mature: 69280

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPARRRAVGVGLVVLAATVAGVLHTVGWLVPVERVVYDQRTQWLHGDAHAPEEIVILY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
VDEYSIRAMEPAVGRWPWPRSLWADLLEFLAHGRPAAVVFDVLFTESAREDGGAGDAAFA
ECCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHH
QASAALGGVVHAMQFLEANPREDRSADPLPKGMADRYALGDTQGWPDPRFQEHGVPVAPL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHCCCCCCCC
ADKAEQLGVVTTGPDRDGVHRRLPPLLPYDGEIYPALGVAALLAAGQDSSTIDWDEQGVQ
HHHHHHCCCEECCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHCHH
WADQTLATDASGQALVNPYAEFDSYPVVELFEAQRQIRRGELADLRVDPEVFNDRIVFVG
HHHHHHHCCCCCCHHCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCEECHHHHCCEEEEEE
ASAAALHDLKATPLSGRTPGVELHASLIGNLLDGQTLRFGPGTIEAVLVPAAAGAVGLAV
CCHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCEEEECCCCEEEEEEEHHHHHHHHHH
LLVPALSARVLLPLAVVAAWTAWVLVQHAAGIVWSWLPLVVGVLLAWVTVLVFLGFTEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DRRRVRQLLAQYVSPAVLQEVVDRRGEVATGEVGSTEQVTLLFSDIRGFTSLSEGQEAAS
HHHHHHHHHHHHHCHHHHHHHHHCCCCEEECCCCCCCEEEEEEHHHHHHHHHHCHHHHHH
VVELLNIHLGEMSEAIFEHDGTLDKFIGDAVMAFWGAPVRVRDHADRAVRAALAMTQRLE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHC
GVNEAVVARGGKPLAIGIGLHTGEVVLGNIGSVRKLDYTVIGDNVNVASRLEDLTKAYGC
CCCHHHHHCCCCEEEEEEECCCCCEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCC
SVLISGDTYADLPQGWQCRYVDRVQVRGRQRMLDLYEPIAPPEGA
EEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AQPARRRAVGVGLVVLAATVAGVLHTVGWLVPVERVVYDQRTQWLHGDAHAPEEIVILY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
VDEYSIRAMEPAVGRWPWPRSLWADLLEFLAHGRPAAVVFDVLFTESAREDGGAGDAAFA
ECCCCCEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHH
QASAALGGVVHAMQFLEANPREDRSADPLPKGMADRYALGDTQGWPDPRFQEHGVPVAPL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHCCCCCCCC
ADKAEQLGVVTTGPDRDGVHRRLPPLLPYDGEIYPALGVAALLAAGQDSSTIDWDEQGVQ
HHHHHHCCCEECCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHCHH
WADQTLATDASGQALVNPYAEFDSYPVVELFEAQRQIRRGELADLRVDPEVFNDRIVFVG
HHHHHHHCCCCCCHHCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCEECHHHHCCEEEEEE
ASAAALHDLKATPLSGRTPGVELHASLIGNLLDGQTLRFGPGTIEAVLVPAAAGAVGLAV
CCHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCEEEECCCCEEEEEEEHHHHHHHHHH
LLVPALSARVLLPLAVVAAWTAWVLVQHAAGIVWSWLPLVVGVLLAWVTVLVFLGFTEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DRRRVRQLLAQYVSPAVLQEVVDRRGEVATGEVGSTEQVTLLFSDIRGFTSLSEGQEAAS
HHHHHHHHHHHHHCHHHHHHHHHCCCCEEECCCCCCCEEEEEEHHHHHHHHHHCHHHHHH
VVELLNIHLGEMSEAIFEHDGTLDKFIGDAVMAFWGAPVRVRDHADRAVRAALAMTQRLE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHC
GVNEAVVARGGKPLAIGIGLHTGEVVLGNIGSVRKLDYTVIGDNVNVASRLEDLTKAYGC
CCCHHHHHCCCCEEEEEEECCCCCEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCC
SVLISGDTYADLPQGWQCRYVDRVQVRGRQRMLDLYEPIAPPEGA
EEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]