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The map label for this gene is trpB [H]

Identifier: 121998583

GI number: 121998583

Start: 1975979

End: 1977193

Strand: Reverse

Name: trpB [H]

Synonym: Hhal_1804

Alternate gene names: 121998583

Gene position: 1977193-1975979 (Counterclockwise)

Preceding gene: 121998584

Following gene: 121998582

Centisome position: 73.82

GC content: 70.78

Gene sequence:

>1215_bases
ATGAGACCTGAGCAGGACGGCGGCGGCCCCGCCGAGGAGCATGATGGGCACTTCGGCCGGTTCGGGGGGCGGTTCGTCTC
CGAGACCCTGGTCGGGCCGCTCGAGGAGTTGACCGAGGCGTACGCCGAGGCGCGCCGCGACCCGGGTTTCCAGGCCGAGC
TCGATCGCGAGTTGCGGGATTTCGTCGGTCGGCCCACTCCGCTGTACCTGGCCGAGCGGCTGACCGCCCGCGCCGGCGGT
GCACGCATCTACTTCAAGCGCGAGGATCTGGCCCATACCGGCGCGCACAAGGTCAACAATACCGTGGGGCAGGCGGTGCT
GGCCGCGCGCATGGGCAAGACGCGGATCATCGCCGAGACCGGGGCGGGGCAGCACGGCGTGGCTACGGCAACCGTCGCGG
CACGCATGGGGCTGGAGTGCGTCGTTTACATGGGGGCCGACGACGTGCAGCGCCAGGCCGCCAACGTCTACCGGATGCGT
CTGCTCGGCGCTGAGGTCCGCGCCGTGGACGCCGGGACGCGCACCCTCAAGGACGCCATGAACGAGGCGATGCGCGACTG
GGTGGCGAATATCGACAACACCTTCTACATCATCGGCACCGTCGCCGGTCCCCATCCCTACCCGACGCTGGTTCGCGACC
TGCAGCGGGTCATCGGTGTCGAGACCCGAGCGCAGATCCTGGAGCGCGAGGGGCGCTTGCCCGACGCCGTGGTCGCCTGC
GTCGGCGGCGGTTCCAACGCCCTGGGGATCTTCCATCCGTTCCTGGATGACGCCGATATCCGGCTCGTCGGGGTCGAGGC
CGGGGGCGAGGGCCTGGCCTCCGGCCGGCACGCCGCCCCGCTCAACGCCGGCCGCCCCGGTGTGCTCCACGGTGCGCGCA
GTTACCTGATGGAGTCCGACGAGGGGCAGATCATCGGTACGCATTCGATCTCCGCCGGGCTCGATTACCCCGGCGTCGGC
CCTGAGCACGCGTGGCTGAAGGATTCCGGGCGCGCCGAGTATGTGACGGTCACCGACGCCGAGGCCCTGGCCGCTTTCCA
CCGGCTCAGCCGCACCGAAGGCATCCTGCCGGCGCTGGAGACCTCCCACGCCGTCGCCCACGCGGAACGCCTGGCCGCGG
AACTCGGCCCGGACGCTGCGCTGGTGGTCAATCTCTCCGGGCGGGGCGATAAGGACATCGCCACGGTCGCGGCGCAGGAG
GGCATCGAGCTGTGA

Upstream 100 bases:

>100_bases
CGCCCCTTCGCCGTGGATGTTAGCAGCGGCGTCGAGTCGGAGCCGGGGATCAAGGACCGGGAGCGCATAGCCCGGTTTCT
CGCGGAGGTGGAACGTGGCG

Downstream 100 bases:

>100_bases
GCCGCATCGCTGAACGTTTCCGTGCCTGCCGTTCCGCCGGCCGGACGGCCTTGATTCCCTACATCACCGGTGGCGACCCG
TCGCCCGATGACACCGTGCG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRPEQDGGGPAEEHDGHFGRFGGRFVSETLVGPLEELTEAYAEARRDPGFQAELDRELRDFVGRPTPLYLAERLTARAGG
ARIYFKREDLAHTGAHKVNNTVGQAVLAARMGKTRIIAETGAGQHGVATATVAARMGLECVVYMGADDVQRQAANVYRMR
LLGAEVRAVDAGTRTLKDAMNEAMRDWVANIDNTFYIIGTVAGPHPYPTLVRDLQRVIGVETRAQILEREGRLPDAVVAC
VGGGSNALGIFHPFLDDADIRLVGVEAGGEGLASGRHAAPLNAGRPGVLHGARSYLMESDEGQIIGTHSISAGLDYPGVG
PEHAWLKDSGRAEYVTVTDAEALAAFHRLSRTEGILPALETSHAVAHAERLAAELGPDAALVVNLSGRGDKDIATVAAQE
GIEL

Sequences:

>Translated_404_residues
MRPEQDGGGPAEEHDGHFGRFGGRFVSETLVGPLEELTEAYAEARRDPGFQAELDRELRDFVGRPTPLYLAERLTARAGG
ARIYFKREDLAHTGAHKVNNTVGQAVLAARMGKTRIIAETGAGQHGVATATVAARMGLECVVYMGADDVQRQAANVYRMR
LLGAEVRAVDAGTRTLKDAMNEAMRDWVANIDNTFYIIGTVAGPHPYPTLVRDLQRVIGVETRAQILEREGRLPDAVVAC
VGGGSNALGIFHPFLDDADIRLVGVEAGGEGLASGRHAAPLNAGRPGVLHGARSYLMESDEGQIIGTHSISAGLDYPGVG
PEHAWLKDSGRAEYVTVTDAEALAAFHRLSRTEGILPALETSHAVAHAERLAAELGPDAALVVNLSGRGDKDIATVAAQE
GIEL
>Mature_404_residues
MRPEQDGGGPAEEHDGHFGRFGGRFVSETLVGPLEELTEAYAEARRDPGFQAELDRELRDFVGRPTPLYLAERLTARAGG
ARIYFKREDLAHTGAHKVNNTVGQAVLAARMGKTRIIAETGAGQHGVATATVAARMGLECVVYMGADDVQRQAANVYRMR
LLGAEVRAVDAGTRTLKDAMNEAMRDWVANIDNTFYIIGTVAGPHPYPTLVRDLQRVIGVETRAQILEREGRLPDAVVAC
VGGGSNALGIFHPFLDDADIRLVGVEAGGEGLASGRHAAPLNAGRPGVLHGARSYLMESDEGQIIGTHSISAGLDYPGVG
PEHAWLKDSGRAEYVTVTDAEALAAFHRLSRTEGILPALETSHAVAHAERLAAELGPDAALVVNLSGRGDKDIATVAAQE
GIEL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=382, Percent_Identity=57.3298429319372, Blast_Score=456, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6321412, Length=386, Percent_Identity=56.2176165803109, Blast_Score=457, Evalue=1e-129,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42987; Mature: 42987

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPEQDGGGPAEEHDGHFGRFGGRFVSETLVGPLEELTEAYAEARRDPGFQAELDRELRD
CCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FVGRPTPLYLAERLTARAGGARIYFKREDLAHTGAHKVNNTVGQAVLAARMGKTRIIAET
HHCCCCHHHHHHHHHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEC
GAGQHGVATATVAARMGLECVVYMGADDVQRQAANVYRMRLLGAEVRAVDAGTRTLKDAM
CCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHH
NEAMRDWVANIDNTFYIIGTVAGPHPYPTLVRDLQRVIGVETRAQILEREGRLPDAVVAC
HHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHEEEE
VGGGSNALGIFHPFLDDADIRLVGVEAGGEGLASGRHAAPLNAGRPGVLHGARSYLMESD
ECCCCCCEEEEHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEECC
EGQIIGTHSISAGLDYPGVGPEHAWLKDSGRAEYVTVTDAEALAAFHRLSRTEGILPALE
CCCEEEECCCCCCCCCCCCCCCCCEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCHHH
TSHAVAHAERLAAELGPDAALVVNLSGRGDKDIATVAAQEGIEL
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MRPEQDGGGPAEEHDGHFGRFGGRFVSETLVGPLEELTEAYAEARRDPGFQAELDRELRD
CCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FVGRPTPLYLAERLTARAGGARIYFKREDLAHTGAHKVNNTVGQAVLAARMGKTRIIAET
HHCCCCHHHHHHHHHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEC
GAGQHGVATATVAARMGLECVVYMGADDVQRQAANVYRMRLLGAEVRAVDAGTRTLKDAM
CCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHH
NEAMRDWVANIDNTFYIIGTVAGPHPYPTLVRDLQRVIGVETRAQILEREGRLPDAVVAC
HHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHEEEE
VGGGSNALGIFHPFLDDADIRLVGVEAGGEGLASGRHAAPLNAGRPGVLHGARSYLMESD
ECCCCCCEEEEHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEECC
EGQIIGTHSISAGLDYPGVGPEHAWLKDSGRAEYVTVTDAEALAAFHRLSRTEGILPALE
CCCEEEECCCCCCCCCCCCCCCCCEECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCHHH
TSHAVAHAERLAAELGPDAALVVNLSGRGDKDIATVAAQEGIEL
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA