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The map label for this gene is glnA [H]

Identifier: 121998361

GI number: 121998361

Start: 1722073

End: 1723488

Strand: Reverse

Name: glnA [H]

Synonym: Hhal_1582

Alternate gene names: 121998361

Gene position: 1723488-1722073 (Counterclockwise)

Preceding gene: 121998362

Following gene: 121998360

Centisome position: 64.35

GC content: 64.41

Gene sequence:

>1416_bases
ATGGCTGCAACCGGTAAGGACGTACTCAAGCTCATCAAGGATGAGGACGTGAAGTTCGTCGACCTGCGCTTCACCGACAC
GCGCGGGAAAGAGATGCACGTAACCCTGCCCGTCTCCCAGGTCGATGAGGACCTGTTCGAGCACGGCAAGATGTTCGACG
GCTCTTCCATCGACGGCTGGAAGGGGATCCAGGAGTCGGACATGATCATGCTCCCGGATGCCGAGAGCGCCGTCCTCGAC
CCCTTCACCGATGAGCCGACCCTCAAGCTGGTCTGTGACATCCTCGAGCCGAGCACTCTGCAGGGCTACGACCGCGATCC
GCGCTCGGCCGCCAAGCGGGCCGAGGCGTATCTGGCCTCCACGGGTATTGGAGATAGTGCCCTGTTCGGTCCCGAGCCGG
AGTTCTTCGTCTTCGACGACGTCCGCTGGGGCGCCGACATGAGCGGCTGCTTCTATAAGGTGGACTCCGAGGAGGCCGGC
TGGAACTCCGAGCGGGTCTACCCAGACGGTAATATCGGTCACCGCCCCGGCGTGAAGGGCGGCTACTTCCCGGTCCCGCC
GGTGGATTCGCTGCACAACATCCGCGGCGCCATGTGTCAGGCCCTGGCCGATATGGGCCTAGAGCCGGAGGTCCACCACC
ACGAGGTGGCCACTGCCGGTCAGGGGGAGATCGGTACCGCGGCCCGTACCCTGGTCAAGAAGGCCGACGAGCTGCAGACG
CTCAAGTACTGCGTGCACAACGTCGCCCACGCCTACGGCAAGACCGCCACCTTTATGCCCAAGCCGCTAGTGGGCGACAA
CGGCAACGGCATGCACGTGCACCAGTCGGTCTCCAAAGGCGGCAACAATATCTTCACCGGGGACCAGTACGGCGGGCTCT
CCGAGGAGGCGCTCTACTACATCGGCGGCATCATCAAGCACGCCAAGGCGATCAACGCCTTCGCCAACGCCTCCACCAAC
AGCTACAAGCGCCTGGTGCCCGGCTTCGAGGCGCCGGTGCTGCTCGCCTACTCGGCGCGCAATCGCTCCGCCTCGGTGCG
GGTGCCCTATGTGGCCAACCCCAAGGCGCGGCGGATCGAGGTCCGCTTCCCGGACTCCACCGGCAACCCGTACCTGACCT
TCGCCGCTATGCTGATGGCCGGTCTCGACGGCATCCGCAACAAGATCCACCCCGGCGAGGCGATGGACAAGGACCTCTAC
GACCTGCCGCCGGAGGAGGAGAAGGAGATCCCCAAGGTCGCCTTCCAGCTCGACGAGGCGCTCGAGGCCCTGGACAACGA
CCGCGAGTTCCTCAAGCAGGGCGGGGTCTTCTCCGACGACCTGATCGACGCCTACATCGAACTGAAGATGGAGGAGGTCA
CCCGCCTTCGCATGACCACCCATCCGGTGGAGTTCGACCTGTATTACAGCGTCTGA

Upstream 100 bases:

>100_bases
CCCGTCTAGCCGAAATCCCAGAAGCTGGCACAGGGATTGCTACCACCTCCGTGAGCCCCGACTGGGGAACATTGATTAGC
CGTTTCGGAGGTGGAACCCC

Downstream 100 bases:

>100_bases
CCTTGGTGCCTCGGCTGGGGCGGGGGTTCCCCCCCGCCCCAGCGGCTCCATTCTGGTCGGATCGCCCGACGGCAACCAAC
GTTCCGCTCCGCGTCAGGAT

Product: glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MAATGKDVLKLIKDEDVKFVDLRFTDTRGKEMHVTLPVSQVDEDLFEHGKMFDGSSIDGWKGIQESDMIMLPDAESAVLD
PFTDEPTLKLVCDILEPSTLQGYDRDPRSAAKRAEAYLASTGIGDSALFGPEPEFFVFDDVRWGADMSGCFYKVDSEEAG
WNSERVYPDGNIGHRPGVKGGYFPVPPVDSLHNIRGAMCQALADMGLEPEVHHHEVATAGQGEIGTAARTLVKKADELQT
LKYCVHNVAHAYGKTATFMPKPLVGDNGNGMHVHQSVSKGGNNIFTGDQYGGLSEEALYYIGGIIKHAKAINAFANASTN
SYKRLVPGFEAPVLLAYSARNRSASVRVPYVANPKARRIEVRFPDSTGNPYLTFAAMLMAGLDGIRNKIHPGEAMDKDLY
DLPPEEEKEIPKVAFQLDEALEALDNDREFLKQGGVFSDDLIDAYIELKMEEVTRLRMTTHPVEFDLYYSV

Sequences:

>Translated_471_residues
MAATGKDVLKLIKDEDVKFVDLRFTDTRGKEMHVTLPVSQVDEDLFEHGKMFDGSSIDGWKGIQESDMIMLPDAESAVLD
PFTDEPTLKLVCDILEPSTLQGYDRDPRSAAKRAEAYLASTGIGDSALFGPEPEFFVFDDVRWGADMSGCFYKVDSEEAG
WNSERVYPDGNIGHRPGVKGGYFPVPPVDSLHNIRGAMCQALADMGLEPEVHHHEVATAGQGEIGTAARTLVKKADELQT
LKYCVHNVAHAYGKTATFMPKPLVGDNGNGMHVHQSVSKGGNNIFTGDQYGGLSEEALYYIGGIIKHAKAINAFANASTN
SYKRLVPGFEAPVLLAYSARNRSASVRVPYVANPKARRIEVRFPDSTGNPYLTFAAMLMAGLDGIRNKIHPGEAMDKDLY
DLPPEEEKEIPKVAFQLDEALEALDNDREFLKQGGVFSDDLIDAYIELKMEEVTRLRMTTHPVEFDLYYSV
>Mature_470_residues
AATGKDVLKLIKDEDVKFVDLRFTDTRGKEMHVTLPVSQVDEDLFEHGKMFDGSSIDGWKGIQESDMIMLPDAESAVLDP
FTDEPTLKLVCDILEPSTLQGYDRDPRSAAKRAEAYLASTGIGDSALFGPEPEFFVFDDVRWGADMSGCFYKVDSEEAGW
NSERVYPDGNIGHRPGVKGGYFPVPPVDSLHNIRGAMCQALADMGLEPEVHHHEVATAGQGEIGTAARTLVKKADELQTL
KYCVHNVAHAYGKTATFMPKPLVGDNGNGMHVHQSVSKGGNNIFTGDQYGGLSEEALYYIGGIIKHAKAINAFANASTNS
YKRLVPGFEAPVLLAYSARNRSASVRVPYVANPKARRIEVRFPDSTGNPYLTFAAMLMAGLDGIRNKIHPGEAMDKDLYD
LPPEEEKEIPKVAFQLDEALEALDNDREFLKQGGVFSDDLIDAYIELKMEEVTRLRMTTHPVEFDLYYSV

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=491, Percent_Identity=21.3849287169043, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790301, Length=468, Percent_Identity=69.4444444444444, Blast_Score=696, Evalue=0.0,
Organism=Escherichia coli, GI87081870, Length=291, Percent_Identity=26.8041237113402, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809
- InterPro:   IPR001637 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 51925; Mature: 51794

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP ; PS00182 GLNA_ADENYLATION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATGKDVLKLIKDEDVKFVDLRFTDTRGKEMHVTLPVSQVDEDLFEHGKMFDGSSIDGW
CCCCHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCCC
KGIQESDMIMLPDAESAVLDPFTDEPTLKLVCDILEPSTLQGYDRDPRSAAKRAEAYLAS
CCCCCCCEEEECCCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
TGIGDSALFGPEPEFFVFDDVRWGADMSGCFYKVDSEEAGWNSERVYPDGNIGHRPGVKG
CCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCEECCCCCCCCCCCCCC
GYFPVPPVDSLHNIRGAMCQALADMGLEPEVHHHEVATAGQGEIGTAARTLVKKADELQT
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LKYCVHNVAHAYGKTATFMPKPLVGDNGNGMHVHQSVSKGGNNIFTGDQYGGLSEEALYY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCEECCCCCCCCCCHHHHHH
IGGIIKHAKAINAFANASTNSYKRLVPGFEAPVLLAYSARNRSASVRVPYVANPKARRIE
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEECCCCCCEEEECEECCCCCEEEE
VRFPDSTGNPYLTFAAMLMAGLDGIRNKIHPGEAMDKDLYDLPPEEEKEIPKVAFQLDEA
EECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHCCCCCHHHHHHHHHHHHHHH
LEALDNDREFLKQGGVFSDDLIDAYIELKMEEVTRLRMTTHPVEFDLYYSV
HHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
>Mature Secondary Structure 
AATGKDVLKLIKDEDVKFVDLRFTDTRGKEMHVTLPVSQVDEDLFEHGKMFDGSSIDGW
CCCHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCCC
KGIQESDMIMLPDAESAVLDPFTDEPTLKLVCDILEPSTLQGYDRDPRSAAKRAEAYLAS
CCCCCCCEEEECCCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
TGIGDSALFGPEPEFFVFDDVRWGADMSGCFYKVDSEEAGWNSERVYPDGNIGHRPGVKG
CCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCEECCCCCCCCCCCCCC
GYFPVPPVDSLHNIRGAMCQALADMGLEPEVHHHEVATAGQGEIGTAARTLVKKADELQT
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LKYCVHNVAHAYGKTATFMPKPLVGDNGNGMHVHQSVSKGGNNIFTGDQYGGLSEEALYY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCEECCCCCCCCCCHHHHHH
IGGIIKHAKAINAFANASTNSYKRLVPGFEAPVLLAYSARNRSASVRVPYVANPKARRIE
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEECCCCCCEEEECEECCCCCEEEE
VRFPDSTGNPYLTFAAMLMAGLDGIRNKIHPGEAMDKDLYDLPPEEEKEIPKVAFQLDEA
EECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHCCCCCHHHHHHHHHHHHHHH
LEALDNDREFLKQGGVFSDDLIDAYIELKMEEVTRLRMTTHPVEFDLYYSV
HHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1969923 [H]