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The map label for this gene is yaeL [C]

Identifier: 121998241

GI number: 121998241

Start: 1575035

End: 1576402

Strand: Reverse

Name: yaeL [C]

Synonym: Hhal_1459

Alternate gene names: 121998241

Gene position: 1576402-1575035 (Counterclockwise)

Preceding gene: 121998242

Following gene: 121998240

Centisome position: 58.85

GC content: 66.01

Gene sequence:

>1368_bases
ATGATGATCGTCTGGAGCGTCATCGCCTTCCTGGTCGCCATCGCCATCTTGGTGACCGTTCACGAGGCGGGCCATTTCTT
CGTGGCCCGCTGGTGTAACGTACGGGTGCGCCGCTTCTCGGTGGGGTTTGGTCGGCCGTTGCTCAGTTGGCGTGGGCGCG
GCCCCGATCACATCGAGTACTGCCTATCGGCCATCCCGCTCGGTGGCTACGTGCAGATGCTCGACGAGCGCGAGGGCGAA
GTAGACCCCGCCGAGCGCCACCGGGCCTTCAACAATCGCCCCCTGGGACAGCGCACGGCCATCGTGGTCGCGGGGCCGGC
AGCCAACTTCCTCTTTGCGGTGGTTGCCTACTGGCTGGTGGCAGTGCTCGGGATTGTCGAGCTGCGGCCGATTGTCGATG
AGCCGATCGCGGATACCCCCGCCGAGATGGCCGGGTTCGAGCGCGGCGAGGAGATCGTCGCTATCGACAGCCGCGATACC
CCCACCTGGCAACGGGTCGCCATGGGGCTAATGAACGCCGGGTTCCATCGGGAGGATGTCCCGGTCACCGTGCGCGACGA
GGCGGGCAATGAATTCTCGCGCACCCTGGATCTCCGCTCCGAACCGAAGCTGAAAGACACCACCGATATCCTCGGGGTCA
TCGGCCTGCGTGCCTACACGCCCGATCTGCCCGCCACCGTCGGTCGCCTGGCTGAGGACGGTGCCGCTGGTCAGGCGGGG
TTGCGTGAAGGCGACCGCATCCGCGCCATCGACGGCGATCCGATCGACTCGTGGCTGGAACTGGTCGAACGCGTCGAGCC
GCGCGCCAACGAGGAGGTAACCCTGACCTACGAGCGGGATGGCGAGGTCCGCGAGATGACGCTCACCCTGGGGGCGCAGC
AGCGGGGCGATGCCGAGGTCGGCATGCTCGGTGTCGGGCCGGCCATCCCCGAGGGGTATCAGGAGCGCATGGAGCGCGAG
GTCCGTTACGGGCCGCTGGGTGGCGTGGTCTACGGGGCCGAGCGCACCTGGGATACCACCGTGGTGACGGTCAAGGTGCT
CGCGCGGATGGTGATGGGCGAGGCATCGCTGAAGAACATCGGCGGCCCGGTGACCATCGGCCAGTTCGCTGGGGATACCG
CCTCCATGGGTGTGGTACCGTTCCTCACCTTCCTGGCGGTGATCAGCATCAGTCTGGGCATCATCAACCTGTTGCCGATC
CCGATCCTCGACGGTGGTCATCTGCTCTACTTCCTCACCGAGGCGATCCGCGGCAAGCCGGTATCCGAGCGGACCCAACT
GATCGGGCAGCAGGTGGGGATCGTGATCCTGCTCGGACTGATGGCGCTGGCCTTTTACAACGATTTTGAGCGCTTGCTTG
GCGGGTAA

Upstream 100 bases:

>100_bases
CCTCCGCCGCCGAAGGATCTGGATTCGGCCCGCGCCATCGATGCGCAGGCCCGCCGTGTGGCCGAGGAGGCCGTGCGGCG
CATCGCGGACTGACTCGACT

Downstream 100 bases:

>100_bases
GCCCGGCGGCGACGACACGTGGCAGATACGGAGCCGGCCCGATGCGGCACACGGTAGAAAAGGGGGCGCTTTGATCCGAC
GCTGGGGGCGCAATACGGTC

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MMIVWSVIAFLVAIAILVTVHEAGHFFVARWCNVRVRRFSVGFGRPLLSWRGRGPDHIEYCLSAIPLGGYVQMLDEREGE
VDPAERHRAFNNRPLGQRTAIVVAGPAANFLFAVVAYWLVAVLGIVELRPIVDEPIADTPAEMAGFERGEEIVAIDSRDT
PTWQRVAMGLMNAGFHREDVPVTVRDEAGNEFSRTLDLRSEPKLKDTTDILGVIGLRAYTPDLPATVGRLAEDGAAGQAG
LREGDRIRAIDGDPIDSWLELVERVEPRANEEVTLTYERDGEVREMTLTLGAQQRGDAEVGMLGVGPAIPEGYQERMERE
VRYGPLGGVVYGAERTWDTTVVTVKVLARMVMGEASLKNIGGPVTIGQFAGDTASMGVVPFLTFLAVISISLGIINLLPI
PILDGGHLLYFLTEAIRGKPVSERTQLIGQQVGIVILLGLMALAFYNDFERLLGG

Sequences:

>Translated_455_residues
MMIVWSVIAFLVAIAILVTVHEAGHFFVARWCNVRVRRFSVGFGRPLLSWRGRGPDHIEYCLSAIPLGGYVQMLDEREGE
VDPAERHRAFNNRPLGQRTAIVVAGPAANFLFAVVAYWLVAVLGIVELRPIVDEPIADTPAEMAGFERGEEIVAIDSRDT
PTWQRVAMGLMNAGFHREDVPVTVRDEAGNEFSRTLDLRSEPKLKDTTDILGVIGLRAYTPDLPATVGRLAEDGAAGQAG
LREGDRIRAIDGDPIDSWLELVERVEPRANEEVTLTYERDGEVREMTLTLGAQQRGDAEVGMLGVGPAIPEGYQERMERE
VRYGPLGGVVYGAERTWDTTVVTVKVLARMVMGEASLKNIGGPVTIGQFAGDTASMGVVPFLTFLAVISISLGIINLLPI
PILDGGHLLYFLTEAIRGKPVSERTQLIGQQVGIVILLGLMALAFYNDFERLLGG
>Mature_455_residues
MMIVWSVIAFLVAIAILVTVHEAGHFFVARWCNVRVRRFSVGFGRPLLSWRGRGPDHIEYCLSAIPLGGYVQMLDEREGE
VDPAERHRAFNNRPLGQRTAIVVAGPAANFLFAVVAYWLVAVLGIVELRPIVDEPIADTPAEMAGFERGEEIVAIDSRDT
PTWQRVAMGLMNAGFHREDVPVTVRDEAGNEFSRTLDLRSEPKLKDTTDILGVIGLRAYTPDLPATVGRLAEDGAAGQAG
LREGDRIRAIDGDPIDSWLELVERVEPRANEEVTLTYERDGEVREMTLTLGAQQRGDAEVGMLGVGPAIPEGYQERMERE
VRYGPLGGVVYGAERTWDTTVVTVKVLARMVMGEASLKNIGGPVTIGQFAGDTASMGVVPFLTFLAVISISLGIINLLPI
PILDGGHLLYFLTEAIRGKPVSERTQLIGQQVGIVILLGLMALAFYNDFERLLGG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=454, Percent_Identity=41.1894273127753, Blast_Score=339, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49714; Mature: 49714

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIVWSVIAFLVAIAILVTVHEAGHFFVARWCNVRVRRFSVGFGRPLLSWRGRGPDHIEY
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEEECCCCCHHHHCCCCCCHHHHH
CLSAIPLGGYVQMLDEREGEVDPAERHRAFNNRPLGQRTAIVVAGPAANFLFAVVAYWLV
HHHHCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
AVLGIVELRPIVDEPIADTPAEMAGFERGEEIVAIDSRDTPTWQRVAMGLMNAGFHREDV
HHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCC
PVTVRDEAGNEFSRTLDLRSEPKLKDTTDILGVIGLRAYTPDLPATVGRLAEDGAAGQAG
CEEEECCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
LREGDRIRAIDGDPIDSWLELVERVEPRANEEVTLTYERDGEVREMTLTLGAQQRGDAEV
CCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCE
GMLGVGPAIPEGYQERMEREVRYGPLGGVVYGAERTWDTTVVTVKVLARMVMGEASLKNI
EEEECCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCHHHHHHC
GGPVTIGQFAGDTASMGVVPFLTFLAVISISLGIINLLPIPILDGGHLLYFLTEAIRGKP
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCC
VSERTQLIGQQVGIVILLGLMALAFYNDFERLLGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMIVWSVIAFLVAIAILVTVHEAGHFFVARWCNVRVRRFSVGFGRPLLSWRGRGPDHIEY
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEEECCCCCHHHHCCCCCCHHHHH
CLSAIPLGGYVQMLDEREGEVDPAERHRAFNNRPLGQRTAIVVAGPAANFLFAVVAYWLV
HHHHCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
AVLGIVELRPIVDEPIADTPAEMAGFERGEEIVAIDSRDTPTWQRVAMGLMNAGFHREDV
HHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCC
PVTVRDEAGNEFSRTLDLRSEPKLKDTTDILGVIGLRAYTPDLPATVGRLAEDGAAGQAG
CEEEECCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
LREGDRIRAIDGDPIDSWLELVERVEPRANEEVTLTYERDGEVREMTLTLGAQQRGDAEV
CCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCE
GMLGVGPAIPEGYQERMEREVRYGPLGGVVYGAERTWDTTVVTVKVLARMVMGEASLKNI
EEEECCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCHHHHHHC
GGPVTIGQFAGDTASMGVVPFLTFLAVISISLGIINLLPIPILDGGHLLYFLTEAIRGKP
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCC
VSERTQLIGQQVGIVILLGLMALAFYNDFERLLGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]