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The map label for this gene is tpm [H]

Identifier: 121998165

GI number: 121998165

Start: 1490662

End: 1491258

Strand: Reverse

Name: tpm [H]

Synonym: Hhal_1383

Alternate gene names: 121998165

Gene position: 1491258-1490662 (Counterclockwise)

Preceding gene: 121998166

Following gene: 121998164

Centisome position: 55.68

GC content: 74.71

Gene sequence:

>597_bases
GTGAGCGGTGACCCGGACCCCCGTCGCGCGCCCTGGGAGGCGCGCTGGCGGGAAGGGCGCACCGGCTGGGACCGGGGCGG
GGTAAGCCCCACCCTGGAGGCCTGGCTGTCGGCTGGGGTGATCCCCGGCCGGCGCGTCCTGGTCCCCGGGGCCGGGCGGG
GCTACGAGGTCGAGGCCCTGGCCCGGCGCGGCTATAAGGTCACGGCGGTGGATATCGCCGCCGAGGCCTGTCAGCAACTA
CGCGACGGCCTGGACGCGGCCGGGGTGGAGGCCCGGGTGGTCCAGGCCGATCTGCTGGCCTGGCAACCGGACACCCCCTT
CGACGCCGTCTACGAGCAGACCTGCCTGTGTGCCCTGGATCCGGCCGACTGGCCGGCCTACGAGCAACGCCTGTACGGCT
GGTTGCGCCCCGGTGGGGTGCTACTGGCGCTGTTCATGCAGACTGGGGCCTCCGGTGGCCCACCCTTCCACTGTGCCCTC
CCCGAGATGGCGACGCTGTTCGACAGCGAGCGCTGGCAGTGGCCGGCCGAGCCGCCGCGCCAGTGGCCCCACCCCAGCGG
CCGCTGGGAGGAGGCGGTGCGGCTGCTGCGGCGTTGA

Upstream 100 bases:

>100_bases
CTACGCCCTGATCCGCGGGCTGCAGGAGGAGAAGCGGCGTATGCAGCTCTCCTGGCAGCCGGGGCAGGGGCCGCCGGCGG
CACCGCATCTGTGAGCGGTT

Downstream 100 bases:

>100_bases
TCGCCGGCCGTCCCGATACCGCCGATCCCCCTTCGAAAATCCAGCCGACGCGGGCACCATAGGGGCCGGACCAACCGGGG
GCAGCCCCATGATCGCGACC

Product: thiopurine S-methyltransferase

Products: NA

Alternate protein names: Thiopurine methyltransferase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSGDPDPRRAPWEARWREGRTGWDRGGVSPTLEAWLSAGVIPGRRVLVPGAGRGYEVEALARRGYKVTAVDIAAEACQQL
RDGLDAAGVEARVVQADLLAWQPDTPFDAVYEQTCLCALDPADWPAYEQRLYGWLRPGGVLLALFMQTGASGGPPFHCAL
PEMATLFDSERWQWPAEPPRQWPHPSGRWEEAVRLLRR

Sequences:

>Translated_198_residues
MSGDPDPRRAPWEARWREGRTGWDRGGVSPTLEAWLSAGVIPGRRVLVPGAGRGYEVEALARRGYKVTAVDIAAEACQQL
RDGLDAAGVEARVVQADLLAWQPDTPFDAVYEQTCLCALDPADWPAYEQRLYGWLRPGGVLLALFMQTGASGGPPFHCAL
PEMATLFDSERWQWPAEPPRQWPHPSGRWEEAVRLLRR
>Mature_197_residues
SGDPDPRRAPWEARWREGRTGWDRGGVSPTLEAWLSAGVIPGRRVLVPGAGRGYEVEALARRGYKVTAVDIAAEACQQLR
DGLDAAGVEARVVQADLLAWQPDTPFDAVYEQTCLCALDPADWPAYEQRLYGWLRPGGVLLALFMQTGASGGPPFHCALP
EMATLFDSERWQWPAEPPRQWPHPSGRWEEAVRLLRR

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TPMT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022474
- InterPro:   IPR008854
- InterPro:   IPR016822 [H]

Pfam domain/function: PF05724 TPMT [H]

EC number: =2.1.1.67 [H]

Molecular weight: Translated: 22031; Mature: 21900

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDPDPRRAPWEARWREGRTGWDRGGVSPTLEAWLSAGVIPGRRVLVPGAGRGYEVEAL
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCEEHHHH
ARRGYKVTAVDIAAEACQQLRDGLDAAGVEARVVQADLLAWQPDTPFDAVYEQTCLCALD
HHCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEC
PADWPAYEQRLYGWLRPGGVLLALFMQTGASGGPPFHCALPEMATLFDSERWQWPAEPPR
CCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCC
QWPHPSGRWEEAVRLLRR
CCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SGDPDPRRAPWEARWREGRTGWDRGGVSPTLEAWLSAGVIPGRRVLVPGAGRGYEVEAL
CCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCEEHHHH
ARRGYKVTAVDIAAEACQQLRDGLDAAGVEARVVQADLLAWQPDTPFDAVYEQTCLCALD
HHCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEC
PADWPAYEQRLYGWLRPGGVLLALFMQTGASGGPPFHCALPEMATLFDSERWQWPAEPPR
CCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCC
QWPHPSGRWEEAVRLLRR
CCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA