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The map label for this gene is apaH

Identifier: 121997987

GI number: 121997987

Start: 1301749

End: 1302585

Strand: Reverse

Name: apaH

Synonym: Hhal_1197

Alternate gene names: 121997987

Gene position: 1302585-1301749 (Counterclockwise)

Preceding gene: 121997988

Following gene: 121997973

Centisome position: 48.63

GC content: 66.19

Gene sequence:

>837_bases
TTGGCCACGTACGCGATCGGTGATATCCAGGGATGCTGCGACCCGCTTAAACGACTGCTGGAGCAGATTCGTTTCGATCC
GGCCCAGGACACCATCTGGTTCGTCGGTGACCTGGTCAATCGCGGTCCGGACTCGCTCGGGGTGCTGCGCCTGGTGCGCA
ACGAGCTGGGCGACCGGGCGATTACGGTCCTCGGCAATCACGATATCCACCTGATGTCGGTCTGGAGTGGCCACGGCCGG
CTGAAGAACTCCGATACCCTGCGCGGTACCCTGGATGCCCCGGATGCGGACGAGCTGATCGAGTGGCTGCGGCACCGGCC
GTTGATGCACGTCGATGAGCGGATGGGCTACGCCATGGCCCACGCCGGATTGCCGCCGGCCTGGAGCGTGGCCGAGGCGC
AGCTCCGGGCCCGAGAGCTGGAGCGGGCCCTGCGCGGTGAGATCCCGTTGGACGATCTGATGGACAATATCTACGGGAAC
CGGCCCATCGAGTGGTCGGACGATCTGGAGGGCTACGACCGCCTGCGTTTTATCACCAACGCCTTCATGCGCATGCGCTT
CGTTGACGGTGAGGGGCGGTTGCTGTTGCGCGAGAAGGGGCGCCCGGGCGCCGCCCCCGAGGGGCATTACCCGTGGTTCA
TCGCCCGCCGGCGCCTGCGGGGGGCGCGCGATCCGGTGAAACTGGTCACCGGGCACTGGTCGCTACTCGGGTTCCACAAT
GACGACGGCGTGCTGAGCATCGACACCGGCTGCCAGTGGGGCAACACGCTGACGGCGGTGCGTATCGACGACGGTAGCGA
GGGGGTATACAGCCTCAAGTGCCCCGAACACGACTGA

Upstream 100 bases:

>100_bases
GCTCGATGTGCTCGAGAAAAAGCTGCAGGCCGCCGCCGCGACGTGAGACCCTGACCGCCGCGAGATCACGTAGGCGTCAT
GCATAGGAAGGAGGCTGGCA

Downstream 100 bases:

>100_bases
TCGACGGCTCAGAGCGCCTCTAGCAGCCGCGGCCAGTCGAAGGCCGGGCCCGGGTCGGTCTTGCGGTCGGGGGCGATGTC
GCTGTGGCCGACGATGCGGC

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MATYAIGDIQGCCDPLKRLLEQIRFDPAQDTIWFVGDLVNRGPDSLGVLRLVRNELGDRAITVLGNHDIHLMSVWSGHGR
LKNSDTLRGTLDAPDADELIEWLRHRPLMHVDERMGYAMAHAGLPPAWSVAEAQLRARELERALRGEIPLDDLMDNIYGN
RPIEWSDDLEGYDRLRFITNAFMRMRFVDGEGRLLLREKGRPGAAPEGHYPWFIARRRLRGARDPVKLVTGHWSLLGFHN
DDGVLSIDTGCQWGNTLTAVRIDDGSEGVYSLKCPEHD

Sequences:

>Translated_278_residues
MATYAIGDIQGCCDPLKRLLEQIRFDPAQDTIWFVGDLVNRGPDSLGVLRLVRNELGDRAITVLGNHDIHLMSVWSGHGR
LKNSDTLRGTLDAPDADELIEWLRHRPLMHVDERMGYAMAHAGLPPAWSVAEAQLRARELERALRGEIPLDDLMDNIYGN
RPIEWSDDLEGYDRLRFITNAFMRMRFVDGEGRLLLREKGRPGAAPEGHYPWFIARRRLRGARDPVKLVTGHWSLLGFHN
DDGVLSIDTGCQWGNTLTAVRIDDGSEGVYSLKCPEHD
>Mature_277_residues
ATYAIGDIQGCCDPLKRLLEQIRFDPAQDTIWFVGDLVNRGPDSLGVLRLVRNELGDRAITVLGNHDIHLMSVWSGHGRL
KNSDTLRGTLDAPDADELIEWLRHRPLMHVDERMGYAMAHAGLPPAWSVAEAQLRARELERALRGEIPLDDLMDNIYGNR
PIEWSDDLEGYDRLRFITNAFMRMRFVDGEGRLLLREKGRPGAAPEGHYPWFIARRRLRGARDPVKLVTGHWSLLGFHND
DGVLSIDTGCQWGNTLTAVRIDDGSEGVYSLKCPEHD

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=266, Percent_Identity=46.6165413533835, Blast_Score=227, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31442; Mature: 31311

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYAIGDIQGCCDPLKRLLEQIRFDPAQDTIWFVGDLVNRGPDSLGVLRLVRNELGDRA
CCCEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCEE
ITVLGNHDIHLMSVWSGHGRLKNSDTLRGTLDAPDADELIEWLRHRPLMHVDERMGYAMA
EEEECCCCEEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
HAGLPPAWSVAEAQLRARELERALRGEIPLDDLMDNIYGNRPIEWSDDLEGYDRLRFITN
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
AFMRMRFVDGEGRLLLREKGRPGAAPEGHYPWFIARRRLRGARDPVKLVTGHWSLLGFHN
HHHHEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCEEEEEEEC
DDGVLSIDTGCQWGNTLTAVRIDDGSEGVYSLKCPEHD
CCCEEEECCCCCCCCEEEEEEECCCCCCEEEECCCCCC
>Mature Secondary Structure 
ATYAIGDIQGCCDPLKRLLEQIRFDPAQDTIWFVGDLVNRGPDSLGVLRLVRNELGDRA
CCEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCEE
ITVLGNHDIHLMSVWSGHGRLKNSDTLRGTLDAPDADELIEWLRHRPLMHVDERMGYAMA
EEEECCCCEEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
HAGLPPAWSVAEAQLRARELERALRGEIPLDDLMDNIYGNRPIEWSDDLEGYDRLRFITN
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
AFMRMRFVDGEGRLLLREKGRPGAAPEGHYPWFIARRRLRGARDPVKLVTGHWSLLGFHN
HHHHEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCEEEEEEEC
DDGVLSIDTGCQWGNTLTAVRIDDGSEGVYSLKCPEHD
CCCEEEECCCCCCCCEEEEEEECCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA