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The map label for this gene is ygfA [C]

Identifier: 121997971

GI number: 121997971

Start: 1286436

End: 1287047

Strand: Reverse

Name: ygfA [C]

Synonym: Hhal_1181

Alternate gene names: 121997971

Gene position: 1287047-1286436 (Counterclockwise)

Preceding gene: 121997972

Following gene: 121997970

Centisome position: 48.05

GC content: 73.04

Gene sequence:

>612_bases
GTGGAGGCCAAGCGCGACATCCGTCGCCGATTGCGCAACCGCCGACGCCGGATCCCGGCCGGCGAGCGCCGTCGCGCCGA
GCTGCGCCTGCGTGACGAGACCCTCAGGCTGGTCGAGACCCAGGGGGTGCAGCGGGTGGCCGGTTACCTCGATGCCGACG
GCGAGGCGCCCACCGGGGCGATCCTCAACGCGCTGCACCAGCGCGGGCAGGCGATCTATCTGCCGGCGCTGCGCCGACAG
TGCCGGCGCATGGGCTTTCGCCGCTGGGCCCCCGAGGCGCCGCTGCGCCCCAATCGTTACGGTGTCCCCGAACCGCCGCC
AGGCCTGGCGGCAGAGCTGCCGGTCCGGGATCTGGATCTGGTGCTGGCGCCGCTGGTCGCCTTCGATCCCGCCGGGCGCC
GACTGGGTATGGGCGGGGGGTTCTACGACGCCACCTTCGCGAGGTTGCGGCGGTACCCCTGGCACCCGCCGCGCATCGTG
GGCCTGGCGTTCAGTTCCCAGGAGGTGGCGCAGTTGCCCGGCGACGCGTGGGATCTGCCCCTGGAGGGGGTGATCACCGA
GCGCGGCTATGTCAGGCTGCCGGTGCGTACGGTCGGATTGGGGAGCGCATGA

Upstream 100 bases:

>100_bases
GGGCAGGCCTGTACGGCATGCGCGGGGGGTGTCCTTATTTCTTCTGCCCCGGTACCCCGCAAGATCCCCTTCGCCCCCCG
TTATTCCGAGGAGTGCCGCC

Downstream 100 bases:

>100_bases
ACCGCTGGGTGATGAAGTCCGAGCCCGATGTGTTCGGCATCGATGATCTAGCCGCGGCGCCGCAGGGTACGGACCGATGG
GACGGGGTGCGTAACTATCA

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MEAKRDIRRRLRNRRRRIPAGERRRAELRLRDETLRLVETQGVQRVAGYLDADGEAPTGAILNALHQRGQAIYLPALRRQ
CRRMGFRRWAPEAPLRPNRYGVPEPPPGLAAELPVRDLDLVLAPLVAFDPAGRRLGMGGGFYDATFARLRRYPWHPPRIV
GLAFSSQEVAQLPGDAWDLPLEGVITERGYVRLPVRTVGLGSA

Sequences:

>Translated_203_residues
MEAKRDIRRRLRNRRRRIPAGERRRAELRLRDETLRLVETQGVQRVAGYLDADGEAPTGAILNALHQRGQAIYLPALRRQ
CRRMGFRRWAPEAPLRPNRYGVPEPPPGLAAELPVRDLDLVLAPLVAFDPAGRRLGMGGGFYDATFARLRRYPWHPPRIV
GLAFSSQEVAQLPGDAWDLPLEGVITERGYVRLPVRTVGLGSA
>Mature_203_residues
MEAKRDIRRRLRNRRRRIPAGERRRAELRLRDETLRLVETQGVQRVAGYLDADGEAPTGAILNALHQRGQAIYLPALRRQ
CRRMGFRRWAPEAPLRPNRYGVPEPPPGLAAELPVRDLDLVLAPLVAFDPAGRRLGMGGGFYDATFARLRRYPWHPPRIV
GLAFSSQEVAQLPGDAWDLPLEGVITERGYVRLPVRTVGLGSA

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=190, Percent_Identity=32.1052631578947, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI1789278, Length=144, Percent_Identity=39.5833333333333, Blast_Score=100, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17510857, Length=193, Percent_Identity=27.4611398963731, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321031, Length=208, Percent_Identity=27.8846153846154, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 22883; Mature: 22883

Theoretical pI: Translated: 11.75; Mature: 11.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAKRDIRRRLRNRRRRIPAGERRRAELRLRDETLRLVETQGVQRVAGYLDADGEAPTGA
CCHHHHHHHHHHHHHHCCCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ILNALHQRGQAIYLPALRRQCRRMGFRRWAPEAPLRPNRYGVPEPPPGLAAELPVRDLDL
HHHHHHHCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VLAPLVAFDPAGRRLGMGGGFYDATFARLRRYPWHPPRIVGLAFSSQEVAQLPGDAWDLP
HHHHHHHCCCCCCEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHCCCCCCCCC
LEGVITERGYVRLPVRTVGLGSA
CCCEEECCCEEECCEEECCCCCC
>Mature Secondary Structure
MEAKRDIRRRLRNRRRRIPAGERRRAELRLRDETLRLVETQGVQRVAGYLDADGEAPTGA
CCHHHHHHHHHHHHHHCCCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ILNALHQRGQAIYLPALRRQCRRMGFRRWAPEAPLRPNRYGVPEPPPGLAAELPVRDLDL
HHHHHHHCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VLAPLVAFDPAGRRLGMGGGFYDATFARLRRYPWHPPRIVGLAFSSQEVAQLPGDAWDLP
HHHHHHHCCCCCCEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHCCCCCCCCC
LEGVITERGYVRLPVRTVGLGSA
CCCEEECCCEEECCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]