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The map label for this gene is hsdM [C]

Identifier: 121997946

GI number: 121997946

Start: 1258837

End: 1260816

Strand: Reverse

Name: hsdM [C]

Synonym: Hhal_1155

Alternate gene names: 121997946

Gene position: 1260816-1258837 (Counterclockwise)

Preceding gene: 121997949

Following gene: 121997945

Centisome position: 47.07

GC content: 65.25

Gene sequence:

>1980_bases
TTGAACACCGAGAATCACTCCCAGATGGCCGGATTCATCTGGTCGGTCGCCGACCTGCTGCGCGGCGATCTCAAGCAATC
CCAGTACGGACGGGTCATCTTGCCGTTTACCCTGCTGCGGCGGCTGGAGTGCGTCCTGGAGCCGACCAAGGAGCAGGTGC
TGGCCGCGGCGAAGGAGCACGCGGACAAGCCGCTGGGGGTGCGCGAGCGGCTTCTGCGCCGGGCGGCCGATCAGCCTTTC
TTCAACACCTCGCCGCTGACCCTGGGGACGCTGTCGGACACGCAGACCGCGGACGACCTGATGAGCTACGTCCAGTCGTT
CAGCCCCGATGCCCGAGAGGTCTTTGAGCACTTCAACTTCGAGGACTTCGTCCAGCAGCTCTCGGCGAACAATCTGCTCT
ACCAGGTGGTGCAGCGCTTCGCGGCCATGGATCTCAGCCCCGGGCGGATCTCCAACTTCGGCATGGGCTCGATCTTCGAG
GAGCTGATCCGCAAGTTCGCCGAGAGCTCCAACGAGACCGCCGGTGAGCACTTCACGCCCCGCGACGTGGTCCACCTGAC
CACCTCGCTGGTGCTCACCGATCAGGACGACAAGCTGCAACCGCACAGCGTGGTCACGGTCTATGACCCGGCCGCCGGCA
CGGGTGGCTTCCTCTCCGAGAGTGACGCCTACATCCAGCAGGTCAGCGATAACGTGACCGTTTCGCTGCACGGCCAGGAG
CTCAACCCGGAGTCCTACGCCATCTGCAAGGCGGACATGCTGATCAAGGGCCAGCAGGTCGAGAACATCAAGCTCGGCAA
CACCCTCTCCGACGACGAGCTCGCCGGCGAGCGCTTCGACTTCATGCTTGCCAATCCGCCCTTCGGCGTGGAGTGGAAGA
AGGTCCAGAAGCAGGTCACCGACGAGCACAAGCGCTGGGGGTACAACGGCCGCTTCGGACCGGGCCTGCCCCGGGTCTCC
GACGGCTCCCTGCTATTTCTGCTGCACCTGGTGAGCAAGGTCCGCGATCCGCGGGAGGGTGGCTCGCGCATCGGCATCAT
CCTCAACGGCTCCCCGCTGTTCACCGGCGGGGCCGGTAGCGGCGAGTCGGAGATCCGTCGCTTCCTGCTTGAGCGCGACC
TGGTGGAGGCCATCGTCGCCCTGCCCACGGACATGTTCTACAACACCGGCATCGCCACCTACGTCTGGATCCTCTCCAAC
GACAAGCCGCCGGAGCGCCGCGGTCGGGTGCAGCTGATCAACGCCACCGAGCGTTACAGCAAGATGCGCAAGTCGCTCGG
ATCCAAGCGGCAGTACATCGACGATACAAACATCGACAACATCGTCCGCCTCTACGGCGCCTTCGAGGAGAGCGAAGAGA
GTAAGCTCTTCCCGGTGGCGGAGTTCGGCTACCGGCGGATCACCGTCGAGCGGCCCCTGCGGCTCAACTTCCAGGCCAGC
GAGGAGCGCATCCGCCGGATCCTCGACGAGAAGCCGATCCAGAAACTCGACGAGGACACCCAGGCCCGCCTCCTGGCCGC
CTGCGAGGCCATGGACGGCCAGATGCTCTACCGGGACCGGCAGGCGTTCACCCGCGACCTGAAGCGTGCCCTGGAGGAGC
GGGAAGTGAAGCTCGGCGCGCCACCGATGAAAGCGGTCCTCAACGCCTTATCCGAGCGCGACCCGGAGGCCAAGCCGTGC
ACCGACGCCAAGGGCAACCCGGAGCCGGACACCAGCCTGCGTGACCACGAGAACGTGCCGCTGACCGAATCCGTCTACGA
CTATTTCGAGCGCGAGGTGCGCCCGCACGTCCCCGACGCCTGGATCGACGAGGCCAAGCGTGACGCCCAGGACGGCGAGG
TGGGCATCGTCGGCTATGAGATCCCCTTCAACCGCCACTTCTACAAGTTCACCCCGCCGCGCCCGCTCGAAGAGATCGAC
GCGGACCTGAAGGTCTGCACGGACCGGATCAAGCGGATGATCGAGGAGCTGTCGGCATGA

Upstream 100 bases:

>100_bases
ATGCCCCGCCCGGGGCCAAGCAGCGCCATCGCGGCACCTGGATACGGTGCGCGGTGCCGGAGACAGGACCTCCAGTTCGA
ACAAGCAACAAGGAGCTGCC

Downstream 100 bases:

>100_bases
TGGGCGGGGCAGCCGTCTTCGCGGCGATCGAGGGCGTCGGGGCGGCGTGCGCCGCGGCGTTGAGTGAAGAGCCTCTAGCG
GCTACACTGTTCAGTAACAA

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MNTENHSQMAGFIWSVADLLRGDLKQSQYGRVILPFTLLRRLECVLEPTKEQVLAAAKEHADKPLGVRERLLRRAADQPF
FNTSPLTLGTLSDTQTADDLMSYVQSFSPDAREVFEHFNFEDFVQQLSANNLLYQVVQRFAAMDLSPGRISNFGMGSIFE
ELIRKFAESSNETAGEHFTPRDVVHLTTSLVLTDQDDKLQPHSVVTVYDPAAGTGGFLSESDAYIQQVSDNVTVSLHGQE
LNPESYAICKADMLIKGQQVENIKLGNTLSDDELAGERFDFMLANPPFGVEWKKVQKQVTDEHKRWGYNGRFGPGLPRVS
DGSLLFLLHLVSKVRDPREGGSRIGIILNGSPLFTGGAGSGESEIRRFLLERDLVEAIVALPTDMFYNTGIATYVWILSN
DKPPERRGRVQLINATERYSKMRKSLGSKRQYIDDTNIDNIVRLYGAFEESEESKLFPVAEFGYRRITVERPLRLNFQAS
EERIRRILDEKPIQKLDEDTQARLLAACEAMDGQMLYRDRQAFTRDLKRALEEREVKLGAPPMKAVLNALSERDPEAKPC
TDAKGNPEPDTSLRDHENVPLTESVYDYFEREVRPHVPDAWIDEAKRDAQDGEVGIVGYEIPFNRHFYKFTPPRPLEEID
ADLKVCTDRIKRMIEELSA

Sequences:

>Translated_659_residues
MNTENHSQMAGFIWSVADLLRGDLKQSQYGRVILPFTLLRRLECVLEPTKEQVLAAAKEHADKPLGVRERLLRRAADQPF
FNTSPLTLGTLSDTQTADDLMSYVQSFSPDAREVFEHFNFEDFVQQLSANNLLYQVVQRFAAMDLSPGRISNFGMGSIFE
ELIRKFAESSNETAGEHFTPRDVVHLTTSLVLTDQDDKLQPHSVVTVYDPAAGTGGFLSESDAYIQQVSDNVTVSLHGQE
LNPESYAICKADMLIKGQQVENIKLGNTLSDDELAGERFDFMLANPPFGVEWKKVQKQVTDEHKRWGYNGRFGPGLPRVS
DGSLLFLLHLVSKVRDPREGGSRIGIILNGSPLFTGGAGSGESEIRRFLLERDLVEAIVALPTDMFYNTGIATYVWILSN
DKPPERRGRVQLINATERYSKMRKSLGSKRQYIDDTNIDNIVRLYGAFEESEESKLFPVAEFGYRRITVERPLRLNFQAS
EERIRRILDEKPIQKLDEDTQARLLAACEAMDGQMLYRDRQAFTRDLKRALEEREVKLGAPPMKAVLNALSERDPEAKPC
TDAKGNPEPDTSLRDHENVPLTESVYDYFEREVRPHVPDAWIDEAKRDAQDGEVGIVGYEIPFNRHFYKFTPPRPLEEID
ADLKVCTDRIKRMIEELSA
>Mature_659_residues
MNTENHSQMAGFIWSVADLLRGDLKQSQYGRVILPFTLLRRLECVLEPTKEQVLAAAKEHADKPLGVRERLLRRAADQPF
FNTSPLTLGTLSDTQTADDLMSYVQSFSPDAREVFEHFNFEDFVQQLSANNLLYQVVQRFAAMDLSPGRISNFGMGSIFE
ELIRKFAESSNETAGEHFTPRDVVHLTTSLVLTDQDDKLQPHSVVTVYDPAAGTGGFLSESDAYIQQVSDNVTVSLHGQE
LNPESYAICKADMLIKGQQVENIKLGNTLSDDELAGERFDFMLANPPFGVEWKKVQKQVTDEHKRWGYNGRFGPGLPRVS
DGSLLFLLHLVSKVRDPREGGSRIGIILNGSPLFTGGAGSGESEIRRFLLERDLVEAIVALPTDMFYNTGIATYVWILSN
DKPPERRGRVQLINATERYSKMRKSLGSKRQYIDDTNIDNIVRLYGAFEESEESKLFPVAEFGYRRITVERPLRLNFQAS
EERIRRILDEKPIQKLDEDTQARLLAACEAMDGQMLYRDRQAFTRDLKRALEEREVKLGAPPMKAVLNALSERDPEAKPC
TDAKGNPEPDTSLRDHENVPLTESVYDYFEREVRPHVPDAWIDEAKRDAQDGEVGIVGYEIPFNRHFYKFTPPRPLEEID
ADLKVCTDRIKRMIEELSA

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=269, Percent_Identity=27.5092936802974, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 74718; Mature: 74718

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTENHSQMAGFIWSVADLLRGDLKQSQYGRVILPFTLLRRLECVLEPTKEQVLAAAKEH
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
ADKPLGVRERLLRRAADQPFFNTSPLTLGTLSDTQTADDLMSYVQSFSPDAREVFEHFNF
CCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHCCH
EDFVQQLSANNLLYQVVQRFAAMDLSPGRISNFGMGSIFEELIRKFAESSNETAGEHFTP
HHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
RDVVHLTTSLVLTDQDDKLQPHSVVTVYDPAAGTGGFLSESDAYIQQVSDNVTVSLHGQE
HHHHHHHHEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCEEEEEECCC
LNPESYAICKADMLIKGQQVENIKLGNTLSDDELAGERFDFMLANPPFGVEWKKVQKQVT
CCCCCEEEEEHHHHCCCCCCCCEECCCCCCCHHHCCCCCCEEECCCCCCCCHHHHHHHHH
DEHKRWGYNGRFGPGLPRVSDGSLLFLLHLVSKVRDPREGGSRIGIILNGSPLFTGGAGS
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEECCCCC
GESEIRRFLLERDLVEAIVALPTDMFYNTGIATYVWILSNDKPPERRGRVQLINATERYS
CHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHEEEEECCCCCCCCCCCEEEECHHHHHH
KMRKSLGSKRQYIDDTNIDNIVRLYGAFEESEESKLFPVAEFGYRRITVERPLRLNFQAS
HHHHHHCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEECCCEEECCCHH
EERIRRILDEKPIQKLDEDTQARLLAACEAMDGQMLYRDRQAFTRDLKRALEEREVKLGA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PPMKAVLNALSERDPEAKPCTDAKGNPEPDTSLRDHENVPLTESVYDYFEREVRPHVPDA
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHH
WIDEAKRDAQDGEVGIVGYEIPFNRHFYKFTPPRPLEEIDADLKVCTDRIKRMIEELSA
HHHHHHCCCCCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTENHSQMAGFIWSVADLLRGDLKQSQYGRVILPFTLLRRLECVLEPTKEQVLAAAKEH
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
ADKPLGVRERLLRRAADQPFFNTSPLTLGTLSDTQTADDLMSYVQSFSPDAREVFEHFNF
CCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHCCH
EDFVQQLSANNLLYQVVQRFAAMDLSPGRISNFGMGSIFEELIRKFAESSNETAGEHFTP
HHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
RDVVHLTTSLVLTDQDDKLQPHSVVTVYDPAAGTGGFLSESDAYIQQVSDNVTVSLHGQE
HHHHHHHHEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCEEEEEECCC
LNPESYAICKADMLIKGQQVENIKLGNTLSDDELAGERFDFMLANPPFGVEWKKVQKQVT
CCCCCEEEEEHHHHCCCCCCCCEECCCCCCCHHHCCCCCCEEECCCCCCCCHHHHHHHHH
DEHKRWGYNGRFGPGLPRVSDGSLLFLLHLVSKVRDPREGGSRIGIILNGSPLFTGGAGS
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEECCCCC
GESEIRRFLLERDLVEAIVALPTDMFYNTGIATYVWILSNDKPPERRGRVQLINATERYS
CHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHEEEEECCCCCCCCCCCEEEECHHHHHH
KMRKSLGSKRQYIDDTNIDNIVRLYGAFEESEESKLFPVAEFGYRRITVERPLRLNFQAS
HHHHHHCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEECCCEEECCCHH
EERIRRILDEKPIQKLDEDTQARLLAACEAMDGQMLYRDRQAFTRDLKRALEEREVKLGA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PPMKAVLNALSERDPEAKPCTDAKGNPEPDTSLRDHENVPLTESVYDYFEREVRPHVPDA
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHH
WIDEAKRDAQDGEVGIVGYEIPFNRHFYKFTPPRPLEEIDADLKVCTDRIKRMIEELSA
HHHHHHCCCCCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]