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The map label for this gene is dtd

Identifier: 121997886

GI number: 121997886

Start: 1187770

End: 1188234

Strand: Reverse

Name: dtd

Synonym: Hhal_1095

Alternate gene names: 121997886

Gene position: 1188234-1187770 (Counterclockwise)

Preceding gene: 121997887

Following gene: 121997885

Centisome position: 44.36

GC content: 69.46

Gene sequence:

>465_bases
ATGATCACCGTTATTCAACGTACAGGCAGTGCCCGGGTTCGGGTTGGTGGCGAGGTCGTTGGCGAGATCGAGCGTGGCCT
GGTGGCGCTGGTCTGCGCCGTTCACGGCGATGGTTCGGCGCAGGCCCAGCGCCTGGCCGAGCGGGTGCTCGGCTACCGGG
TCTTCCCGGATGCCGAGGGGCGTATGAATGGCTCCGCCCTCGATCTCGGGTGCGGCGTGCTGGCCGTACCGCAATTCACG
CTGGCTGCGGATACCCGCAAGGGCATGCGACCGAGCTTTGGCCCCGCGGCCGATCCGCAGACCGGCCAGGCGCTGTTCGA
GACCTTCCTTGAGGCCCTGCGCGAGCGGGCCACGGGCCCCGTGGCCAGTGGCGTGTTCGGGGCGGACATGCAGGTCGAGT
TGGTCAATGACGGCCCGGTGACCTTCTGGCTGGAAGCGCCGCCGAGGCCCGCTGGCCCCGTGTGA

Upstream 100 bases:

>100_bases
TTCGATTGCCGGTAGCCGAGGTTTACAATGCCTCACCGCCGGTGGCGGGGGAATCAGGGGGTGCCGGAGTGCTTGTAAGA
AAAATCCTATATCTCTCGCG

Downstream 100 bases:

>100_bases
TATCCTCGGTCGCCCGTCGGGCGGAAGGCCCGTCAACGATTCCAACTGCGAGGGCGTCACGGCCATGGCCAAGCGAACGG
CAGAAGTCGAGCGCACCACC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MITVIQRTGSARVRVGGEVVGEIERGLVALVCAVHGDGSAQAQRLAERVLGYRVFPDAEGRMNGSALDLGCGVLAVPQFT
LAADTRKGMRPSFGPAADPQTGQALFETFLEALRERATGPVASGVFGADMQVELVNDGPVTFWLEAPPRPAGPV

Sequences:

>Translated_154_residues
MITVIQRTGSARVRVGGEVVGEIERGLVALVCAVHGDGSAQAQRLAERVLGYRVFPDAEGRMNGSALDLGCGVLAVPQFT
LAADTRKGMRPSFGPAADPQTGQALFETFLEALRERATGPVASGVFGADMQVELVNDGPVTFWLEAPPRPAGPV
>Mature_154_residues
MITVIQRTGSARVRVGGEVVGEIERGLVALVCAVHGDGSAQAQRLAERVLGYRVFPDAEGRMNGSALDLGCGVLAVPQFT
LAADTRKGMRPSFGPAADPQTGQALFETFLEALRERATGPVASGVFGADMQVELVNDGPVTFWLEAPPRPAGPV

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=150, Percent_Identity=37.3333333333333, Blast_Score=93, Evalue=9e-20,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=53.7931034482759, Blast_Score=150, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=37.0860927152318, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=35.1351351351351, Blast_Score=92, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281361569, Length=151, Percent_Identity=37.0860927152318, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_HALHL (A1WW09)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001002673.1
- ProteinModelPortal:   A1WW09
- SMR:   A1WW09
- STRING:   A1WW09
- GeneID:   4711216
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1095
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   A1WW09
- ProtClustDB:   PRK05273
- BioCyc:   HHAL349124:HHAL_1095-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16117; Mature: 16117

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVIQRTGSARVRVGGEVVGEIERGLVALVCAVHGDGSAQAQRLAERVLGYRVFPDAEG
CEEEEEECCCCEEEECHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCEECCCCCCC
RMNGSALDLGCGVLAVPQFTLAADTRKGMRPSFGPAADPQTGQALFETFLEALRERATGP
CCCCCEEECCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
VASGVFGADMQVELVNDGPVTFWLEAPPRPAGPV
CCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MITVIQRTGSARVRVGGEVVGEIERGLVALVCAVHGDGSAQAQRLAERVLGYRVFPDAEG
CEEEEEECCCCEEEECHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCEECCCCCCC
RMNGSALDLGCGVLAVPQFTLAADTRKGMRPSFGPAADPQTGQALFETFLEALRERATGP
CCCCCEEECCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
VASGVFGADMQVELVNDGPVTFWLEAPPRPAGPV
CCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA