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The map label for this gene is bioD [H]

Identifier: 121997750

GI number: 121997750

Start: 1031416

End: 1032126

Strand: Reverse

Name: bioD [H]

Synonym: Hhal_0959

Alternate gene names: 121997750

Gene position: 1032126-1031416 (Counterclockwise)

Preceding gene: 121997751

Following gene: 121997748

Centisome position: 38.53

GC content: 74.68

Gene sequence:

>711_bases
ATGAGCGCGGGGCAGGCGCACGGCGCTGATCCGGCCGGGGTGTTCATCACCGGCACCGACACCGGCGTCGGCAAGACGGT
CTACGCCGGCGGGCTGATCCGTCTGCTGCAGCGCCACCAGATCCCGGTGGCGGCCATGAAGCCGGTGGCCGCCGGGTGCC
GGCGCACCGCCGAAGGGCTGCGCAACGACGACGCCGAGCAGCTGAAGGCGCTGATCGATCCGGCGCTGCCCTACGAGACC
GTCAACCCGTGCGCCCTGGAGGCGGCCGCGGCCCCCCATCTGGTGGCCGACGAGCAGGGGCTGTCCATCGATGGCGCCGG
GCTGGTGGCCGCGGCCCGGGCGTTGGCGCAGACGCGCTTCACCGTGGTCGAGGGGGCCGGCGGCTGGCGGGTGCCCCTGG
GGCCAACGCAGGACATGGCGGCGCTGGCGCGGGGGATCGGTCTGCCGGTGGTGCTGGTGGTCGGCGTTCGGTTGGGGTGT
CTGAACCACGCCCTGCTCAGCGCCGAGGCGATCCGCGCCGACGGCTTGGTCCTGGCCGGTTGGGTGGCGTGTGAACTGGA
CGCCGACGACCCGCGGCGGGATGCCCAGATCGCCAGCCTGGATGCGCGGCTGCCGGCGCCCCGGCTCGGGCGCATCCCCG
TCCTCCAGGAGCCCACGCCGGAGCAGGTGGCCGATTACCTGGAGCCGCCCCCCGGGGTGTTGGAGGCGTAG

Upstream 100 bases:

>100_bases
TGGTCTACGGGCACGCCTGGGGGATGGGCGGAACCCCGCAGCGGGCCGATGACACCGGCGAGGTCCGGCTCGACGTCCAC
GGCATCCGGCGGAGGCGGCG

Downstream 100 bases:

>100_bases
GCCGGCCGCGCCTGGACATGCCGATGCCAGTCGCCCCTCTCCACGAAGCGAGCGTAGGGCGGCACCCGGTTGATCCAGTA
GATCTGACAGGTCAGGGGGC

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSAGQAHGADPAGVFITGTDTGVGKTVYAGGLIRLLQRHQIPVAAMKPVAAGCRRTAEGLRNDDAEQLKALIDPALPYET
VNPCALEAAAAPHLVADEQGLSIDGAGLVAAARALAQTRFTVVEGAGGWRVPLGPTQDMAALARGIGLPVVLVVGVRLGC
LNHALLSAEAIRADGLVLAGWVACELDADDPRRDAQIASLDARLPAPRLGRIPVLQEPTPEQVADYLEPPPGVLEA

Sequences:

>Translated_236_residues
MSAGQAHGADPAGVFITGTDTGVGKTVYAGGLIRLLQRHQIPVAAMKPVAAGCRRTAEGLRNDDAEQLKALIDPALPYET
VNPCALEAAAAPHLVADEQGLSIDGAGLVAAARALAQTRFTVVEGAGGWRVPLGPTQDMAALARGIGLPVVLVVGVRLGC
LNHALLSAEAIRADGLVLAGWVACELDADDPRRDAQIASLDARLPAPRLGRIPVLQEPTPEQVADYLEPPPGVLEA
>Mature_235_residues
SAGQAHGADPAGVFITGTDTGVGKTVYAGGLIRLLQRHQIPVAAMKPVAAGCRRTAEGLRNDDAEQLKALIDPALPYETV
NPCALEAAAAPHLVADEQGLSIDGAGLVAAARALAQTRFTVVEGAGGWRVPLGPTQDMAALARGIGLPVVLVVGVRLGCL
NHALLSAEAIRADGLVLAGWVACELDADDPRRDAQIASLDARLPAPRLGRIPVLQEPTPEQVADYLEPPPGVLEA

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=211, Percent_Identity=43.6018957345972, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI87081944, Length=215, Percent_Identity=40, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24310; Mature: 24179

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGQAHGADPAGVFITGTDTGVGKTVYAGGLIRLLQRHQIPVAAMKPVAAGCRRTAEGL
CCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RNDDAEQLKALIDPALPYETVNPCALEAAAAPHLVADEQGLSIDGAGLVAAARALAQTRF
CCCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHE
TVVEGAGGWRVPLGPTQDMAALARGIGLPVVLVVGVRLGCLNHALLSAEAIRADGLVLAG
EEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
WVACELDADDPRRDAQIASLDARLPAPRLGRIPVLQEPTPEQVADYLEPPPGVLEA
EEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SAGQAHGADPAGVFITGTDTGVGKTVYAGGLIRLLQRHQIPVAAMKPVAAGCRRTAEGL
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RNDDAEQLKALIDPALPYETVNPCALEAAAAPHLVADEQGLSIDGAGLVAAARALAQTRF
CCCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHE
TVVEGAGGWRVPLGPTQDMAALARGIGLPVVLVVGVRLGCLNHALLSAEAIRADGLVLAG
EEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
WVACELDADDPRRDAQIASLDARLPAPRLGRIPVLQEPTPEQVADYLEPPPGVLEA
EEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA