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The map label for this gene is coaX

Identifier: 121997665

GI number: 121997665

Start: 946900

End: 947664

Strand: Reverse

Name: coaX

Synonym: Hhal_0874

Alternate gene names: 121997665

Gene position: 947664-946900 (Counterclockwise)

Preceding gene: 121997666

Following gene: 121997664

Centisome position: 35.38

GC content: 74.77

Gene sequence:

>765_bases
ATGAGGCTCCTGCTCGATCTCGGCAACAGCGCGATCAAGTGGGCTGTTGTCCCGCCGGGGGGCGCGGCCTGGCAGACCGG
CCGCCTGGCCTACGCCGACGGCGCCGGACCCGAGGACACGGCAGCGGCTCTGGGCGGGCGGATCCCAAGCACCGTGGCGC
CGGCGCGCATCTGCGTGGCGAGCGTCCTCGCCCCGGCCTGGCAGCGGCGCTTCGATACGGCGCTGGAGCGCGCCTGGGGG
GGGCCGGTTCAACACCTGGTCGCCAGCGCCGCGGCGGCTGGGGTCACCAACGGCTACGACCAGCCCGAGCAGCTCGGTGT
TGACCGATGGGCCGCGCTCATCGGTGCCCGAGCTGTAGCGCCGGAGGGCGCCTGCATCGTTGATGTTGGCACGGCCATCA
CCGTCGACGGACTGGACGCCGACGGCCGGCACCTCGGCGGTGCCATCTTTCCCGGCGCGCGCCTGCTGCACCAGGCCTTG
GCACGCGGCACCGCGCGACTCCCCGACAGCCCAATCGGCGCCGCCGCCCTGCCGGCGCGCTCCACCGAGGAAGGCATCGC
CGCAGGCGTCGCCGTCGGCGCCGGAGCAGCGGTGACCGCCCTGGCCGATGCGATCCTCGCCGCCTGCCCCCCGGGCGCGC
AGCGCCTGATCACGGGGGGCGGTGGCGGCGAGCTAGCCGCGGGGCTGAGCCCGGCCTGGTGCCACCGTCCCTACTTGGTC
CTGGAAGGACTGCTGCACTGGAGTCGACACGAGGCCCGGCGTTGA

Upstream 100 bases:

>100_bases
TCGCCCGGGGTATCGACGAGCACGGCCGACTGCGCGTCGAGACGGACCAGGGACCGGTCGCGCTCGCCAGCGGCGAGGCC
CACCTGCAGCGGAGCGCGCC

Downstream 100 bases:

>100_bases
CCCGTTTGCGGCCCTGGCTGGCATCGATCCTCTTGGTCGTGACGCTGCCGGTCCCGGTGGCCGCCCTGGAGCTCGTACCC
CGGGGCGAGGGCGACGAGGG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRLLLDLGNSAIKWAVVPPGGAAWQTGRLAYADGAGPEDTAAALGGRIPSTVAPARICVASVLAPAWQRRFDTALERAWG
GPVQHLVASAAAAGVTNGYDQPEQLGVDRWAALIGARAVAPEGACIVDVGTAITVDGLDADGRHLGGAIFPGARLLHQAL
ARGTARLPDSPIGAAALPARSTEEGIAAGVAVGAGAAVTALADAILAACPPGAQRLITGGGGGELAAGLSPAWCHRPYLV
LEGLLHWSRHEARR

Sequences:

>Translated_254_residues
MRLLLDLGNSAIKWAVVPPGGAAWQTGRLAYADGAGPEDTAAALGGRIPSTVAPARICVASVLAPAWQRRFDTALERAWG
GPVQHLVASAAAAGVTNGYDQPEQLGVDRWAALIGARAVAPEGACIVDVGTAITVDGLDADGRHLGGAIFPGARLLHQAL
ARGTARLPDSPIGAAALPARSTEEGIAAGVAVGAGAAVTALADAILAACPPGAQRLITGGGGGELAAGLSPAWCHRPYLV
LEGLLHWSRHEARR
>Mature_254_residues
MRLLLDLGNSAIKWAVVPPGGAAWQTGRLAYADGAGPEDTAAALGGRIPSTVAPARICVASVLAPAWQRRFDTALERAWG
GPVQHLVASAAAAGVTNGYDQPEQLGVDRWAALIGARAVAPEGACIVDVGTAITVDGLDADGRHLGGAIFPGARLLHQAL
ARGTARLPDSPIGAAALPARSTEEGIAAGVAVGAGAAVTALADAILAACPPGAQRLITGGGGGELAAGLSPAWCHRPYLV
LEGLLHWSRHEARR

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_HALHL (A1WVD8)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001002452.1
- ProteinModelPortal:   A1WVD8
- SMR:   A1WVD8
- STRING:   A1WVD8
- GeneID:   4710421
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_0874
- eggNOG:   COG1521
- OMA:   HLGGFIC
- ProtClustDB:   PRK13322
- BioCyc:   HHAL349124:HHAL_0874-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 25587; Mature: 25587

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: ACT_SITE 108-108 BINDING 99-99 BINDING 131-131 BINDING 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLDLGNSAIKWAVVPPGGAAWQTGRLAYADGAGPEDTAAALGGRIPSTVAPARICVA
CEEEEECCCCEEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHH
SVLAPAWQRRFDTALERAWGGPVQHLVASAAAAGVTNGYDQPEQLGVDRWAALIGARAVA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
PEGACIVDVGTAITVDGLDADGRHLGGAIFPGARLLHQALARGTARLPDSPIGAAALPAR
CCCCEEEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
STEEGIAAGVAVGAGAAVTALADAILAACPPGAQRLITGGGGGELAAGLSPAWCHRPYLV
CCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHCCCCHHHHCCHHHH
LEGLLHWSRHEARR
HHHHHHHHHHHCCC
>Mature Secondary Structure
MRLLLDLGNSAIKWAVVPPGGAAWQTGRLAYADGAGPEDTAAALGGRIPSTVAPARICVA
CEEEEECCCCEEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHH
SVLAPAWQRRFDTALERAWGGPVQHLVASAAAAGVTNGYDQPEQLGVDRWAALIGARAVA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
PEGACIVDVGTAITVDGLDADGRHLGGAIFPGARLLHQALARGTARLPDSPIGAAALPAR
CCCCEEEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
STEEGIAAGVAVGAGAAVTALADAILAACPPGAQRLITGGGGGELAAGLSPAWCHRPYLV
CCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHCCCCHHHHCCHHHH
LEGLLHWSRHEARR
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA