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The map label for this gene is insF1 [C]

Identifier: 121997416

GI number: 121997416

Start: 694911

End: 695609

Strand: Reverse

Name: insF1 [C]

Synonym: Hhal_0616

Alternate gene names: 121997416

Gene position: 695609-694911 (Counterclockwise)

Preceding gene: 121997417

Following gene: 121997415

Centisome position: 25.97

GC content: 64.09

Gene sequence:

>699_bases
GTGAATCGGGCCTATTACAGCACTGCCACGCTTTGCGGGGTACTGGGCGTCTCCCCCAGCGGTTTCTACGCGTGGCGCAA
TCGCGGCCGCTCAGTCCGTGCGGCGACAGACGCCGCTCTGACGGAGCGGATCGAGGCGATCCACGACAATTCTCGCGGCA
CATACGGTGCACCGCGGATTCATGCCGAGCTCCGGGATGAAGGCTGGCGCTTCTCCGCAAAGCGAGTCGCCCGCCTGATG
CGGGCCGCTGGCCTGCAAGGCGTCAGCCGCCGCAAGGGAACGATTGCGACGATTCCGGACCGGGACAGCGAAGACAAGCC
GGATCTCGTCGAGCGGGACTTCACCGCAAATGGGCCAGACCAGCTCTATGTCGCGGATATCACGTACGTTCCAACGTGGG
CGGGATTCCTGTACCTCGCTGTCGTCATCGACGTGTTCTCACGGCGTGTCGTGGGCTGGTCAATGGCTGGCCACATGCGC
ACGGAGATCGTCCTCGACGCCCTCGAGATGGCGATCTGGCAGCGCCGTCCAGAGGCCGTCATACACCACTCGGACCGTGG
GTCGCAGTACACATCCATTGCCTTCGGCAACCGCTGCCGGGAGGCCGGGGTGCGCCCTTCGATGAGTTCGGTGGGCGACT
GTTACGACAACTCGATGGCCGAGAGTGGTCTTGCCCACCAACCGTGGACACCTCAATAG

Upstream 100 bases:

>100_bases
ATAAGCGGCTGCGCGAAGAGCGGGAGATTCTGTCAAAAGCCGCGGCCTGGTTCGCTCGGGAGACCGACGCGAAGTCCAGC
GGATCTTCGAGTTCGTCGAA

Downstream 100 bases:

>100_bases
CTACCATTCGACGAGGTGATCCATGACGAGGCAAGCTATTCAGATGAGCAAGACCAAGACGAAATCCAAGCGCACACGCT
ACAGCCCGGCCTATCGAGAC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNRAYYSTATLCGVLGVSPSGFYAWRNRGRSVRAATDAALTERIEAIHDNSRGTYGAPRIHAELRDEGWRFSAKRVARLM
RAAGLQGVSRRKGTIATIPDRDSEDKPDLVERDFTANGPDQLYVADITYVPTWAGFLYLAVVIDVFSRRVVGWSMAGHMR
TEIVLDALEMAIWQRRPEAVIHHSDRGSQYTSIAFGNRCREAGVRPSMSSVGDCYDNSMAESGLAHQPWTPQ

Sequences:

>Translated_232_residues
MNRAYYSTATLCGVLGVSPSGFYAWRNRGRSVRAATDAALTERIEAIHDNSRGTYGAPRIHAELRDEGWRFSAKRVARLM
RAAGLQGVSRRKGTIATIPDRDSEDKPDLVERDFTANGPDQLYVADITYVPTWAGFLYLAVVIDVFSRRVVGWSMAGHMR
TEIVLDALEMAIWQRRPEAVIHHSDRGSQYTSIAFGNRCREAGVRPSMSSVGDCYDNSMAESGLAHQPWTPQ
>Mature_232_residues
MNRAYYSTATLCGVLGVSPSGFYAWRNRGRSVRAATDAALTERIEAIHDNSRGTYGAPRIHAELRDEGWRFSAKRVARLM
RAAGLQGVSRRKGTIATIPDRDSEDKPDLVERDFTANGPDQLYVADITYVPTWAGFLYLAVVIDVFSRRVVGWSMAGHMR
TEIVLDALEMAIWQRRPEAVIHHSDRGSQYTSIAFGNRCREAGVRPSMSSVGDCYDNSMAESGLAHQPWTPQ

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=227, Percent_Identity=41.8502202643172, Blast_Score=174, Evalue=7e-44,
Organism=Escherichia coli, GI1788405, Length=226, Percent_Identity=40.2654867256637, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1787263, Length=226, Percent_Identity=40.2654867256637, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786753, Length=226, Percent_Identity=40.2654867256637, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786570, Length=226, Percent_Identity=40.2654867256637, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786490, Length=226, Percent_Identity=40.2654867256637, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789981, Length=188, Percent_Identity=31.9148936170213, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 25840; Mature: 25840

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS50994 INTEGRASE ; PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRAYYSTATLCGVLGVSPSGFYAWRNRGRSVRAATDAALTERIEAIHDNSRGTYGAPRI
CCCCHHHHHHHHHHHCCCCCCHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCHH
HAELRDEGWRFSAKRVARLMRAAGLQGVSRRKGTIATIPDRDSEDKPDLVERDFTANGPD
HHHHHCCCCCCCHHHHHHHHHHHCCCCHHHCCCCEEECCCCCCCCCCCHHHCCCCCCCCC
QLYVADITYVPTWAGFLYLAVVIDVFSRRVVGWSMAGHMRTEIVLDALEMAIWQRRPEAV
EEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHE
IHHSDRGSQYTSIAFGNRCREAGVRPSMSSVGDCYDNSMAESGLAHQPWTPQ
EEECCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNRAYYSTATLCGVLGVSPSGFYAWRNRGRSVRAATDAALTERIEAIHDNSRGTYGAPRI
CCCCHHHHHHHHHHHCCCCCCHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCHH
HAELRDEGWRFSAKRVARLMRAAGLQGVSRRKGTIATIPDRDSEDKPDLVERDFTANGPD
HHHHHCCCCCCCHHHHHHHHHHHCCCCHHHCCCCEEECCCCCCCCCCCHHHCCCCCCCCC
QLYVADITYVPTWAGFLYLAVVIDVFSRRVVGWSMAGHMRTEIVLDALEMAIWQRRPEAV
EEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHE
IHHSDRGSQYTSIAFGNRCREAGVRPSMSSVGDCYDNSMAESGLAHQPWTPQ
EEECCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]