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The map label for this gene is aroA

Identifier: 121997366

GI number: 121997366

Start: 639498

End: 640832

Strand: Reverse

Name: aroA

Synonym: Hhal_0565

Alternate gene names: 121997366

Gene position: 640832-639498 (Counterclockwise)

Preceding gene: 121997367

Following gene: 121997365

Centisome position: 23.93

GC content: 73.41

Gene sequence:

>1335_bases
ATGGAGGGCGAAAACTGGCGGGTTGCCCCGGGCGGGGCCCTGCACGGCGAGGCCCGGGTGCCGGGGGACAAGTCCATCTC
CCACCGGGCGGTGATGCTCGGCGCCCTGGCCGACGGCACGACACGGATCACCGGGATGCTGGAGGGGGCCGACGTCCTGG
CGACCATCGATGTCTTCCGCGCCCTGGGGGTGGCCATCGAGGGCCCGGAGCAGGGTGCGGTCACGGTGCACGGGGTGGGC
TGGGAAGGGCTGCGCCCGCCCGCCCGGGAGCTGGACGTGGGCAACTCCGGCACCTCCATGCGCCTGCTCGCCGGGCTACT
GGCCGGATTGCCGTTCGACACCGTGCTCACCGGCGACGCCTCGCTCAACCGCCGGCCCATGCGGCGGGTCACCGAGCCCC
TGGCGGAGATGGGCGCGCGGATCACCACCAGCGACGCCGGCACCGCGCCGTTGCGTATCCACGGCGGCAGCCCGCTGGCC
GGCATCGACTACACGCTGCCGGTGGCCAGTGCCCAGGTGAAATCGGCGTTGCTGCTCGCCGGCATGCGCGCCGAGGGCCA
CACCTGCGTCACCGAGCCGGCCCCCACCCGGGATCACACCGAGCGGATGCTGCAGGGGTTCGGCTACCCGGTCTCCCGCG
ATCTGGCTACAGTCTGTCTCGAAGGCGGGCGGCGGCTCTACGGCACCGGCGTCGACGTGCCGGCGGACATCTCCTCGGCC
GCCTTCCTGCTGGTCGCGGCGAGCATCGCCCCGGGCTCGGACTTGACCCTGCGCCACGTGGGCTGGAACCCCACGCGCAC
CGGCGTGGTGGAGATCCTCCGGCGCATGGGGGCCGATATCGAGGTACTGAGCACCGACGAGGTCGGCGGCGAGCCGGTGG
CGGACCTGCGCGTCCGCTCCGCCGCGTTGCGCGGTATCGCCATCCCCGAGGAGCTGGTGCCGCTGGCCATCGACGAGTTC
CCGGCGCTGTTCATCGCCGCCGCCTGCGCCGAGGGCGAGACGCAGCTCACCGGCGCCGCCGAGCTGCGCGTCAAGGAGTC
GGATCGCATCGCGGTGATGGCCGAGGGGCTGCAGACACTGGGCGTGACCGTCGAGCCCCGCGAGGACGGTGTGCGCATCG
TCGGCCAGCCCGTGCTCGGCGGCGGCCGGGTGCACAGCCATACCGACCACCGCATCGCCATGGCCTTCGCCGTCGCCGCC
CTGCGCGCCGAGGCGCCCGTGGAGATCGAGGCCTGCGAGAACGTGCGCACCTCTTTCCCCGGGTTCGTGGAGCTCCTGCG
CCGCCTGGGCATGGGGGTTGAGGTCGATGGCCCCCACGATCGCGGCACCGCCTGA

Upstream 100 bases:

>100_bases
TGGCCGCCGGCGACGACGAGCAGGTCCTGCGTGTCTTCGAAAACGCCCAGGAGGCCCGCGCCGGCTTCCTGCGCCTGCTG
GAGGGCCGCTCGTGAGCGCA

Downstream 100 bases:

>100_bases
ACAGTGAACCCTGACCCCTAACCCCTGGACCCGCACAAACCTCATGACCGAAACCGACCTCCCCCCCGTACTCGCCATCG
ACGGACCCAGCGGCGCCGGC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MEGENWRVAPGGALHGEARVPGDKSISHRAVMLGALADGTTRITGMLEGADVLATIDVFRALGVAIEGPEQGAVTVHGVG
WEGLRPPARELDVGNSGTSMRLLAGLLAGLPFDTVLTGDASLNRRPMRRVTEPLAEMGARITTSDAGTAPLRIHGGSPLA
GIDYTLPVASAQVKSALLLAGMRAEGHTCVTEPAPTRDHTERMLQGFGYPVSRDLATVCLEGGRRLYGTGVDVPADISSA
AFLLVAASIAPGSDLTLRHVGWNPTRTGVVEILRRMGADIEVLSTDEVGGEPVADLRVRSAALRGIAIPEELVPLAIDEF
PALFIAAACAEGETQLTGAAELRVKESDRIAVMAEGLQTLGVTVEPREDGVRIVGQPVLGGGRVHSHTDHRIAMAFAVAA
LRAEAPVEIEACENVRTSFPGFVELLRRLGMGVEVDGPHDRGTA

Sequences:

>Translated_444_residues
MEGENWRVAPGGALHGEARVPGDKSISHRAVMLGALADGTTRITGMLEGADVLATIDVFRALGVAIEGPEQGAVTVHGVG
WEGLRPPARELDVGNSGTSMRLLAGLLAGLPFDTVLTGDASLNRRPMRRVTEPLAEMGARITTSDAGTAPLRIHGGSPLA
GIDYTLPVASAQVKSALLLAGMRAEGHTCVTEPAPTRDHTERMLQGFGYPVSRDLATVCLEGGRRLYGTGVDVPADISSA
AFLLVAASIAPGSDLTLRHVGWNPTRTGVVEILRRMGADIEVLSTDEVGGEPVADLRVRSAALRGIAIPEELVPLAIDEF
PALFIAAACAEGETQLTGAAELRVKESDRIAVMAEGLQTLGVTVEPREDGVRIVGQPVLGGGRVHSHTDHRIAMAFAVAA
LRAEAPVEIEACENVRTSFPGFVELLRRLGMGVEVDGPHDRGTA
>Mature_444_residues
MEGENWRVAPGGALHGEARVPGDKSISHRAVMLGALADGTTRITGMLEGADVLATIDVFRALGVAIEGPEQGAVTVHGVG
WEGLRPPARELDVGNSGTSMRLLAGLLAGLPFDTVLTGDASLNRRPMRRVTEPLAEMGARITTSDAGTAPLRIHGGSPLA
GIDYTLPVASAQVKSALLLAGMRAEGHTCVTEPAPTRDHTERMLQGFGYPVSRDLATVCLEGGRRLYGTGVDVPADISSA
AFLLVAASIAPGSDLTLRHVGWNPTRTGVVEILRRMGADIEVLSTDEVGGEPVADLRVRSAALRGIAIPEELVPLAIDEF
PALFIAAACAEGETQLTGAAELRVKESDRIAVMAEGLQTLGVTVEPREDGVRIVGQPVLGGGRVHSHTDHRIAMAFAVAA
LRAEAPVEIEACENVRTSFPGFVELLRRLGMGVEVDGPHDRGTA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=437, Percent_Identity=30.4347826086957, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320332, Length=464, Percent_Identity=26.7241379310345, Blast_Score=113, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_HALHL (A1WUI9)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001002153.1
- ProteinModelPortal:   A1WUI9
- SMR:   A1WUI9
- STRING:   A1WUI9
- GeneID:   4709625
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_0565
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- PhylomeDB:   A1WUI9
- ProtClustDB:   PRK02427
- BioCyc:   HHAL349124:HHAL_0565-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 46447; Mature: 46447

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGENWRVAPGGALHGEARVPGDKSISHRAVMLGALADGTTRITGMLEGADVLATIDVFR
CCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHH
ALGVAIEGPEQGAVTVHGVGWEGLRPPARELDVGNSGTSMRLLAGLLAGLPFDTVLTGDA
HHCCEEECCCCCCEEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCHHHEEECCC
SLNRRPMRRVTEPLAEMGARITTSDAGTAPLRIHGGSPLAGIDYTLPVASAQVKSALLLA
CCCCCHHHHHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCCEEECCCCHHHHHHHHHHH
GMRAEGHTCVTEPAPTRDHTERMLQGFGYPVSRDLATVCLEGGRRLYGTGVDVPADISSA
CCCCCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHH
AFLLVAASIAPGSDLTLRHVGWNPTRTGVVEILRRMGADIEVLSTDEVGGEPVADLRVRS
EEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHH
AALRGIAIPEELVPLAIDEFPALFIAAACAEGETQLTGAAELRVKESDRIAVMAEGLQTL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCEEEEEEECCCCEEEEECCHHHH
GVTVEPREDGVRIVGQPVLGGGRVHSHTDHRIAMAFAVAALRAEAPVEIEACENVRTSFP
CCEEECCCCCCEEEECCCCCCCEECCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCH
GFVELLRRLGMGVEVDGPHDRGTA
HHHHHHHHHCCCEEECCCCCCCCC
>Mature Secondary Structure
MEGENWRVAPGGALHGEARVPGDKSISHRAVMLGALADGTTRITGMLEGADVLATIDVFR
CCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCHHHHHHHHHH
ALGVAIEGPEQGAVTVHGVGWEGLRPPARELDVGNSGTSMRLLAGLLAGLPFDTVLTGDA
HHCCEEECCCCCCEEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCHHHEEECCC
SLNRRPMRRVTEPLAEMGARITTSDAGTAPLRIHGGSPLAGIDYTLPVASAQVKSALLLA
CCCCCHHHHHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCCEEECCCCHHHHHHHHHHH
GMRAEGHTCVTEPAPTRDHTERMLQGFGYPVSRDLATVCLEGGRRLYGTGVDVPADISSA
CCCCCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHH
AFLLVAASIAPGSDLTLRHVGWNPTRTGVVEILRRMGADIEVLSTDEVGGEPVADLRVRS
EEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHH
AALRGIAIPEELVPLAIDEFPALFIAAACAEGETQLTGAAELRVKESDRIAVMAEGLQTL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCEEEEEEECCCCEEEEECCHHHH
GVTVEPREDGVRIVGQPVLGGGRVHSHTDHRIAMAFAVAALRAEAPVEIEACENVRTSFP
CCEEECCCCCCEEEECCCCCCCEECCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCH
GFVELLRRLGMGVEVDGPHDRGTA
HHHHHHHHHCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA