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The map label for this gene is PE_PGRS59 [H]

Identifier: 121639515

GI number: 121639515

Start: 4015486

End: 4016964

Strand: Reverse

Name: PE_PGRS59 [H]

Synonym: BCG_3660c

Alternate gene names: 121639515

Gene position: 4016964-4015486 (Counterclockwise)

Preceding gene: 121639516

Following gene: 121639511

Centisome position: 91.83

GC content: 75.12

Gene sequence:

>1479_bases
ATGTCGTTTGTGATTGCCGTTCCGGAGTTCCTGTCGGCGGCGGCCACGGATTTGGCCAATCTCGGTTCGACGATCAGCGC
GGCTAACGCGGCTGCCAGCATCCCGACCACCGGCGTGCTGGCCGCGGGCGCAGATGACGTATCGGCGGCGATTGCGGCGC
TCTTCGGCGCGCACGCCCAGGCGTATCAGACGATCAGCGCGCAGGCGGCGACGTTTCATGCCCAGTTCGTGCAGACCTTG
AGTGCGGGTGCGGGGGCGTATGCCAACGCCGAGGCCGCCAACGTTCAGCAGAGTTTGCTGAACGCGATCAATGCGCCCAC
CCAGGCACTGTTGGGACGTCCGTTGATCGGTGATGGTGCCGACGGGACGGCGCCCGGGCAAAACGGCGGGGCGGGCGGGC
TGCTGTATGGCAATGGCGGTAATGGCGCGGCCGGGGTGAACGCGGGGATTGCCGGCGGCAGCGGCGGGGCGGCCGGGTTG
ATCGGCAACGGCGGATCCGGTGGTGCCGGCGGAGCCGGTGCGGCCGGCGGGTCCGGCGGACAAGGCGGGCTGCTGTACGG
CAACGGCGGCGCGGGCGGCAACGGCGGGGCGGCGACTATCCCCGGCGGCAACGGCGGCGCCGGTGGTGCCGGCGGCAACG
CGTGGCTATTCGGCAACGGTGGGGCCGGGGGGCTCGGCGCGGCCGGCGCGGCGGGTGCCGCCGGGGTCAACCCCCTGACC
GTCCCGGCGGGCCAGGGCAGCATGGGTAACAACGGTGAACCGGGCGGCCCGGCCAGCCAGGCACCGAGTTCGGGCAAACC
GGTGGCACCGGTGGCACTGGCGGTACTGGCCTGTCCGTTGGCGGGACCGGCGGGACCGGCGGAAACGGTGGCCCCGGCGC
GCCCGGCGGCACCGGGGGGACCGGCGGGGCCGGCGGCTCTGGCGGTCGGGGTGGGCTCCTGGTCGGCGACGGCGGCGCAG
GTGGCATCGGGGGCACAGGGGGCGAAGGCGGCATCGGCGCCCGGGGCGGCACCGGCGGTCAGGGCGGAATGGGCGGCGCC
GGGCAACCAGGCGTTGGGGGTGACGCTGGTGACGGGGGTAACGGCGGGATCGGCGGTGACGGCGGCGCCGGCGGAGACGG
CGGCGCGGGCGGCGCGGGCGGCGCGGGCGGCCTGTTCGGCGTCTCCGGTAGCTCCGGGCTGGGCGGTGCCGCCGGTAGCG
GGGGTAATGGCGGGGGCGGTGGTGAGCCCGGTGTGGCCGGCTCCCCGGGCGTTGGGCCTGCGGGCCGTGGCGGCGACGGC
AACCTCGGCCAGTTCGGCCCTGAAGGTGCACCCGGCCAGCCCGGCCAGCCGGGCCAGCCCGGTTGACATCGTTGCAGCGG
GTCCGTCAGCACCCCGCCGCCTGCTGGAGCAGCTACCGAGTGTCACTGGGCCGGTCGAGGCCCTCGCGCGCGTCGAGTTT
TGCGGCCAGGGCGTCGACCTTATTGCCGAGCTCGGCTAG

Upstream 100 bases:

>100_bases
GGTCCATCGGCCGTATTAGGCGAAAACCGCGACCGCCGATCCGCTGTGACAATAGACTCTGCTGACGTCGGTTTGTCCGG
AAGCTGTTCGGAGGTGGCCA

Downstream 100 bases:

>100_bases
GTAGTCGACGATCGTCTTGTCGCCGAGTACCGGCCAGCCGCGGCCCTCGATGCCGCGTAGCTGGTCCCACACCTCCTCGA
GCAGGATGCGATCGTCACGC

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MSFVIAVPEFLSAAATDLANLGSTISAANAAASIPTTGVLAAGADDVSAAIAALFGAHAQAYQTISAQAATFHAQFVQTL
SAGAGAYANAEAANVQQSLLNAINAPTQALLGRPLIGDGADGTAPGQNGGAGGLLYGNGGNGAAGVNAGIAGGSGGAAGL
IGNGGSGGAGGAGAAGGSGGQGGLLYGNGGAGGNGGAATIPGGNGGAGGAGGNAWLFGNGGAGGLGAAGAAGAAGVNPLT
VPAGQGSMGNNGEPGGPASQAPSSGKPVAPVALAVLACPLAGPAGPAETVAPARPAAPGGPAGPAALAVGVGSWSATAAQ
VASGAQGAKAASAPGAAPAVRAEWAAPGNQALGVTLVTGVTAGSAVTAAPAETAARAARAARAACSASPVAPGWAVPPVA
GVMAGAVVSPVWPAPRALGLRAVAATATSASSALKVHPASPASRASPVDIVAAGPSAPRRLLEQLPSVTGPVEALARVEF
CGQGVDLIAELG

Sequences:

>Translated_492_residues
MSFVIAVPEFLSAAATDLANLGSTISAANAAASIPTTGVLAAGADDVSAAIAALFGAHAQAYQTISAQAATFHAQFVQTL
SAGAGAYANAEAANVQQSLLNAINAPTQALLGRPLIGDGADGTAPGQNGGAGGLLYGNGGNGAAGVNAGIAGGSGGAAGL
IGNGGSGGAGGAGAAGGSGGQGGLLYGNGGAGGNGGAATIPGGNGGAGGAGGNAWLFGNGGAGGLGAAGAAGAAGVNPLT
VPAGQGSMGNNGEPGGPASQAPSSGKPVAPVALAVLACPLAGPAGPAETVAPARPAAPGGPAGPAALAVGVGSWSATAAQ
VASGAQGAKAASAPGAAPAVRAEWAAPGNQALGVTLVTGVTAGSAVTAAPAETAARAARAARAACSASPVAPGWAVPPVA
GVMAGAVVSPVWPAPRALGLRAVAATATSASSALKVHPASPASRASPVDIVAAGPSAPRRLLEQLPSVTGPVEALARVEF
CGQGVDLIAELG
>Mature_491_residues
SFVIAVPEFLSAAATDLANLGSTISAANAAASIPTTGVLAAGADDVSAAIAALFGAHAQAYQTISAQAATFHAQFVQTLS
AGAGAYANAEAANVQQSLLNAINAPTQALLGRPLIGDGADGTAPGQNGGAGGLLYGNGGNGAAGVNAGIAGGSGGAAGLI
GNGGSGGAGGAGAAGGSGGQGGLLYGNGGAGGNGGAATIPGGNGGAGGAGGNAWLFGNGGAGGLGAAGAAGAAGVNPLTV
PAGQGSMGNNGEPGGPASQAPSSGKPVAPVALAVLACPLAGPAGPAETVAPARPAAPGGPAGPAALAVGVGSWSATAAQV
ASGAQGAKAASAPGAAPAVRAEWAAPGNQALGVTLVTGVTAGSAVTAAPAETAARAARAARAACSASPVAPGWAVPPVAG
VMAGAVVSPVWPAPRALGLRAVAATATSASSALKVHPASPASRASPVDIVAAGPSAPRRLLEQLPSVTGPVEALARVEFC
GQGVDLIAELG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 44637; Mature: 44506

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVIAVPEFLSAAATDLANLGSTISAANAAASIPTTGVLAAGADDVSAAIAALFGAHAQ
CCEEEECHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHH
AYQTISAQAATFHAQFVQTLSAGAGAYANAEAANVQQSLLNAINAPTQALLGRPLIGDGA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCC
DGTAPGQNGGAGGLLYGNGGNGAAGVNAGIAGGSGGAAGLIGNGGSGGAGGAGAAGGSGG
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
QGGLLYGNGGAGGNGGAATIPGGNGGAGGAGGNAWLFGNGGAGGLGAAGAAGAAGVNPLT
CCCEEECCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEE
VPAGQGSMGNNGEPGGPASQAPSSGKPVAPVALAVLACPLAGPAGPAETVAPARPAAPGG
ECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCC
PAGPAALAVGVGSWSATAAQVASGAQGAKAASAPGAAPAVRAEWAAPGNQALGVTLVTGV
CCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEECC
TAGSAVTAAPAETAARAARAARAACSASPVAPGWAVPPVAGVMAGAVVSPVWPAPRALGL
CCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
RAVAATATSASSALKVHPASPASRASPVDIVAAGPSAPRRLLEQLPSVTGPVEALARVEF
HHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHH
CGQGVDLIAELG
HCCCHHHHHCCC
>Mature Secondary Structure 
SFVIAVPEFLSAAATDLANLGSTISAANAAASIPTTGVLAAGADDVSAAIAALFGAHAQ
CEEEECHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHH
AYQTISAQAATFHAQFVQTLSAGAGAYANAEAANVQQSLLNAINAPTQALLGRPLIGDGA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCC
DGTAPGQNGGAGGLLYGNGGNGAAGVNAGIAGGSGGAAGLIGNGGSGGAGGAGAAGGSGG
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
QGGLLYGNGGAGGNGGAATIPGGNGGAGGAGGNAWLFGNGGAGGLGAAGAAGAAGVNPLT
CCCEEECCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEE
VPAGQGSMGNNGEPGGPASQAPSSGKPVAPVALAVLACPLAGPAGPAETVAPARPAAPGG
ECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCC
PAGPAALAVGVGSWSATAAQVASGAQGAKAASAPGAAPAVRAEWAAPGNQALGVTLVTGV
CCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEECC
TAGSAVTAAPAETAARAARAARAACSASPVAPGWAVPPVAGVMAGAVVSPVWPAPRALGL
CCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
RAVAATATSASSALKVHPASPASRASPVDIVAAGPSAPRRLLEQLPSVTGPVEALARVEF
HHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHH
CGQGVDLIAELG
HCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]