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The map label for this gene is yfbE [C]

Identifier: 121639327

GI number: 121639327

Start: 3807341

End: 3808393

Strand: Reverse

Name: yfbE [C]

Synonym: BCG_3472c

Alternate gene names: 121639327

Gene position: 3808393-3807341 (Counterclockwise)

Preceding gene: 121639328

Following gene: 121639323

Centisome position: 87.06

GC content: 64.77

Gene sequence:

>1053_bases
ATGAAGATCCGAACGTTATCCGGCTCGGTGCTGGAGCCGCCGTCCGCAGTACGCGCGACCCCAGGCACGTCCATGTTAAA
ACTCGAGCCGGGTGGCTCGACGATCCCCAAGATCCCCTTCATCCGCCCGAGCTTTCCCGGGCCAGCCGAGCTCGCCGAGG
ACTTCGTACAGATCGCCCAGGCTAACTGGTACACGAACTTCGGTCCGAACGAGCGGCGGTTTGCCCGCGCCCTGCGCGAC
TATCTGGGACCTCATCTGCACGTTGCTACCCTCGCCAACGGCACCCTGGCACTCCTCGCGGCGCTCCACGTCAGTTTCGG
CGCCGGTACGCGGGACCGCTACCTGCTGATGCCGTCGTTCACGTTCGTCGGCGTGGCTCAGGCTGCGCTATGGACTGGGT
ACCGTCCCTGGTTCATCGACATCGACGCCAACACATGGCAGCCATGCGTCCACTCCGCCCGCGCCGTCATCGAACGCTTC
CGCGACCGGATCGCCGGCATCCTGCTGGCCAATGTGTTCGGCGTCGGCAATCCCCAGATCAGCGTCTGGGAGGAGCTCGC
CGCCGAATGGGAGCTACCGATTGTGCTCGACTCGGCGGCCGGCTTCGGCTCCACGTACGCCGACGGCGAGCGCCTCGGTG
GACGCGGTGCATGCGAGATCTTCTCCTTCCATGCGACCAAGCCGTTCGCGGTTGGTGAGGGCGGCGCTCTGGTTTCTCGC
GATCCACGGCTCGTCGAGCACGCATACAAGTTCCAGAACTTCGGCTTGGTGCAAACACGCGAGTCCATCCAGCTCGGAAT
GAACGGCAAGCTGTCGGAGATCAGCGCCGCTATTGGCCTACGCCAACTAGTCGGGCTTGATCGCCGCCTGGCAAGTCGCC
GCAAGGTCCTCGAGTGCTATCGCACCGGTATGGCCGACGCGGGTGTGCGTTTCCAGGACAACGCCAATGTTGCGTCGCTC
TGTTTCGCGAGCGCTTGCTGCACGTCCGCCGACCACAAGGCCGCGGTTCTGGGTAGCCTGCGTAGGCACGCGATCGAGGC
GCGCGACTACTAG

Upstream 100 bases:

>100_bases
CGCGGTAACTGCTTCAGGCGCCGATGCCAACGATGGTGCGACGAAGTGCGCTGCGGAAACTGTCCCGACGCGCTGCAAAC
GGACCTTGAGCTCTGCATAT

Downstream 100 bases:

>100_bases
AACCCACCGCAGCACCGACATCCGTACTTTGTGACGAATGCCGAGTTAGTCGAGTCGACCGATCTAGCCGTCACGGCGGA
CATTTGCTCGCGAATCGTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKIRTLSGSVLEPPSAVRATPGTSMLKLEPGGSTIPKIPFIRPSFPGPAELAEDFVQIAQANWYTNFGPNERRFARALRD
YLGPHLHVATLANGTLALLAALHVSFGAGTRDRYLLMPSFTFVGVAQAALWTGYRPWFIDIDANTWQPCVHSARAVIERF
RDRIAGILLANVFGVGNPQISVWEELAAEWELPIVLDSAAGFGSTYADGERLGGRGACEIFSFHATKPFAVGEGGALVSR
DPRLVEHAYKFQNFGLVQTRESIQLGMNGKLSEISAAIGLRQLVGLDRRLASRRKVLECYRTGMADAGVRFQDNANVASL
CFASACCTSADHKAAVLGSLRRHAIEARDY

Sequences:

>Translated_350_residues
MKIRTLSGSVLEPPSAVRATPGTSMLKLEPGGSTIPKIPFIRPSFPGPAELAEDFVQIAQANWYTNFGPNERRFARALRD
YLGPHLHVATLANGTLALLAALHVSFGAGTRDRYLLMPSFTFVGVAQAALWTGYRPWFIDIDANTWQPCVHSARAVIERF
RDRIAGILLANVFGVGNPQISVWEELAAEWELPIVLDSAAGFGSTYADGERLGGRGACEIFSFHATKPFAVGEGGALVSR
DPRLVEHAYKFQNFGLVQTRESIQLGMNGKLSEISAAIGLRQLVGLDRRLASRRKVLECYRTGMADAGVRFQDNANVASL
CFASACCTSADHKAAVLGSLRRHAIEARDY
>Mature_350_residues
MKIRTLSGSVLEPPSAVRATPGTSMLKLEPGGSTIPKIPFIRPSFPGPAELAEDFVQIAQANWYTNFGPNERRFARALRD
YLGPHLHVATLANGTLALLAALHVSFGAGTRDRYLLMPSFTFVGVAQAALWTGYRPWFIDIDANTWQPCVHSARAVIERF
RDRIAGILLANVFGVGNPQISVWEELAAEWELPIVLDSAAGFGSTYADGERLGGRGACEIFSFHATKPFAVGEGGALVSR
DPRLVEHAYKFQNFGLVQTRESIQLGMNGKLSEISAAIGLRQLVGLDRRLASRRKVLECYRTGMADAGVRFQDNANVASL
CFASACCTSADHKAAVLGSLRRHAIEARDY

Specific function: Unknown

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family

Homologues:

Organism=Escherichia coli, GI145693159, Length=275, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI2367285, Length=218, Percent_Identity=30.7339449541284, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3402_MYCTU (Q50723)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   G70735
- RefSeq:   NP_217919.1
- RefSeq:   NP_338033.1
- ProteinModelPortal:   Q50723
- EnsemblBacteria:   EBMYCT00000001485
- EnsemblBacteria:   EBMYCT00000071754
- GeneID:   887910
- GeneID:   926602
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3510
- KEGG:   mtu:Rv3402c
- TIGR:   MT3510
- TubercuList:   Rv3402c
- GeneTree:   EBGT00050000017174
- HOGENOM:   HBG565353
- OMA:   IVYSFHA
- ProtClustDB:   CLSK792471
- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000390

Pfam domain/function: PF01041 DegT_DnrJ_EryC1; SSF53383 PyrdxlP-dep_Trfase_major

EC number: NA

Molecular weight: Translated: 38078; Mature: 38078

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRTLSGSVLEPPSAVRATPGTSMLKLEPGGSTIPKIPFIRPSFPGPAELAEDFVQIAQ
CEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ANWYTNFGPNERRFARALRDYLGPHLHVATLANGTLALLAALHVSFGAGTRDRYLLMPSF
HCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCH
TFVGVAQAALWTGYRPWFIDIDANTWQPCVHSARAVIERFRDRIAGILLANVFGVGNPQI
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
SVWEELAAEWELPIVLDSAAGFGSTYADGERLGGRGACEIFSFHATKPFAVGEGGALVSR
HHHHHHHHCCCCCEEEECCCCCCCCCCCCHHCCCCCCEEEEEEECCCCEEECCCCCEECC
DPRLVEHAYKFQNFGLVQTRESIQLGMNGKLSEISAAIGLRQLVGLDRRLASRRKVLECY
CHHHHHHHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTGMADAGVRFQDNANVASLCFASACCTSADHKAAVLGSLRRHAIEARDY
HCCCCCCCCEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIRTLSGSVLEPPSAVRATPGTSMLKLEPGGSTIPKIPFIRPSFPGPAELAEDFVQIAQ
CEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ANWYTNFGPNERRFARALRDYLGPHLHVATLANGTLALLAALHVSFGAGTRDRYLLMPSF
HCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCH
TFVGVAQAALWTGYRPWFIDIDANTWQPCVHSARAVIERFRDRIAGILLANVFGVGNPQI
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
SVWEELAAEWELPIVLDSAAGFGSTYADGERLGGRGACEIFSFHATKPFAVGEGGALVSR
HHHHHHHHCCCCCEEEECCCCCCCCCCCCHHCCCCCCEEEEEEECCCCEEECCCCCEECC
DPRLVEHAYKFQNFGLVQTRESIQLGMNGKLSEISAAIGLRQLVGLDRRLASRRKVLECY
CHHHHHHHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTGMADAGVRFQDNANVASLCFASACCTSADHKAAVLGSLRRHAIEARDY
HCCCCCCCCEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036