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The map label for this gene is moaA3 [H]

Identifier: 121639250

GI number: 121639250

Start: 3699287

End: 3700351

Strand: Reverse

Name: moaA3 [H]

Synonym: BCG_3392c

Alternate gene names: 121639250

Gene position: 3700351-3699287 (Counterclockwise)

Preceding gene: 121639254

Following gene: 121639249

Centisome position: 84.59

GC content: 57.75

Gene sequence:

>1065_bases
GTGAGCCGGTCCGGCTTGTGCATCAATGAATCCCCCATCAGGGACCGCTGTGGTCGCACCATGGGTGATCTGCGGCTTTC
TGTGATCGATCAGTGCAACCTCCGCTGCCGCTACTGCATGCCCGAGGCCGAGTACGCCTGGTTGCCGCGGGCGGATCTGC
TGTCTGTGGACGAAATCAGCCTGATCGTCGATGCATTTATCGCTGTCGGTGTCGATAAAATTCGGCTCACCGGTGGAGAA
CCGCTGATCCGCTCGGATCTGGCGGCAATCATTGAGGTTATAAGCGCGAAAGTTGGCGATGGCAGCGGTTTACAGGATTT
GGCGATCACAACTAATGGCGTGCTGCTCGCGGACCAGGCCAGAAAGTTAAAATCGGCGGGCATGCGGCGCATCACCATTA
GTCTTGATACGTTGCGGCCGGACCGGTTCAAAGCAATCAGCCAGCGCGGGACCCACTATAAAGTTATCGAAGGCATTGAG
GCGGTTGCGGCGGCGGGCTTCACCGATACGAAGCTTGATTCCGTGGTGATACGTGGCTTCAACGATGATGAGTTGTCCGA
TCTGATCGAATTCGCTCGCAACGTCAATGCCGAGGTGAGATTCATTGAATACATGGACGTCGGCGGTGCGACGCAATGGT
CGATGGACAAGGTCTTCACGAAAGCGCAGATGCTGTCAACTCTCGGGAAGAAATACGGTCCCATCGCGGCCTTGCCGAAG
TACGATTCCGCGCCCGCGAACCGCTACAGATTGCCGGACGGAACAACATTCGGCATCATTGCTTCGACCACCGAGCCATT
CTGTGCAACCTGTGACAGGTCGCGACTGACCGCCGATGGCATCTGGCTACATTGCCTTTACGCCCTGTCCGGCATCAATT
TGCGGGAATCCGTGCGTGCGGGAGCGTCCGCCAATGACGTTGTGCAGATTCTGCAGCGTGGCTGGCGGGACCGCGCGAAC
CGTGGGGCAGAACAACGCTTGGCCCAACGAACGCGACAGGTCTTTCTTCCGGTGTCCCGCTTGAAACGCGACCCACATCT
GGAGATGCACACCAGAGGCGGATAA

Upstream 100 bases:

>100_bases
TCGGTGGCCTTGTCGGCGGAGCTATCCAATGACTCGGGTTTTTCATCCAGCATTGTCCGGACCGGAACAGTCGCGCTATC
AGATCACGGATGTCGCCTCG

Downstream 100 bases:

>100_bases
TTCCGGCCGGTCTGGTGCCCATGCCCGCATGCGCGCACTCGCTGGGCGACCAGGTGCGACATCCACCATCAATCCAACCA
AGTCCAGGAGGGAACCATGG

Product: putative molybdenum cofactor biosynthesis protein A moaA1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSRSGLCINESPIRDRCGRTMGDLRLSVIDQCNLRCRYCMPEAEYAWLPRADLLSVDEISLIVDAFIAVGVDKIRLTGGE
PLIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQARKLKSAGMRRITISLDTLRPDRFKAISQRGTHYKVIEGIE
AVAAAGFTDTKLDSVVIRGFNDDELSDLIEFARNVNAEVRFIEYMDVGGATQWSMDKVFTKAQMLSTLGKKYGPIAALPK
YDSAPANRYRLPDGTTFGIIASTTEPFCATCDRSRLTADGIWLHCLYALSGINLRESVRAGASANDVVQILQRGWRDRAN
RGAEQRLAQRTRQVFLPVSRLKRDPHLEMHTRGG

Sequences:

>Translated_354_residues
MSRSGLCINESPIRDRCGRTMGDLRLSVIDQCNLRCRYCMPEAEYAWLPRADLLSVDEISLIVDAFIAVGVDKIRLTGGE
PLIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQARKLKSAGMRRITISLDTLRPDRFKAISQRGTHYKVIEGIE
AVAAAGFTDTKLDSVVIRGFNDDELSDLIEFARNVNAEVRFIEYMDVGGATQWSMDKVFTKAQMLSTLGKKYGPIAALPK
YDSAPANRYRLPDGTTFGIIASTTEPFCATCDRSRLTADGIWLHCLYALSGINLRESVRAGASANDVVQILQRGWRDRAN
RGAEQRLAQRTRQVFLPVSRLKRDPHLEMHTRGG
>Mature_353_residues
SRSGLCINESPIRDRCGRTMGDLRLSVIDQCNLRCRYCMPEAEYAWLPRADLLSVDEISLIVDAFIAVGVDKIRLTGGEP
LIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQARKLKSAGMRRITISLDTLRPDRFKAISQRGTHYKVIEGIEA
VAAAGFTDTKLDSVVIRGFNDDELSDLIEFARNVNAEVRFIEYMDVGGATQWSMDKVFTKAQMLSTLGKKYGPIAALPKY
DSAPANRYRLPDGTTFGIIASTTEPFCATCDRSRLTADGIWLHCLYALSGINLRESVRAGASANDVVQILQRGWRDRANR
GAEQRLAQRTRQVFLPVSRLKRDPHLEMHTRGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=300, Percent_Identity=39.6666666666667, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI22027536, Length=300, Percent_Identity=39.6666666666667, Blast_Score=233, Evalue=2e-61,
Organism=Escherichia coli, GI1786999, Length=288, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17561210, Length=315, Percent_Identity=36.5079365079365, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI32566329, Length=317, Percent_Identity=35.3312302839117, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI32566331, Length=317, Percent_Identity=35.3312302839117, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI28574490, Length=290, Percent_Identity=38.6206896551724, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI28574488, Length=290, Percent_Identity=38.6206896551724, Blast_Score=201, Evalue=9e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 39080; Mature: 38949

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSGLCINESPIRDRCGRTMGDLRLSVIDQCNLRCRYCMPEAEYAWLPRADLLSVDEIS
CCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
LIVDAFIAVGVDKIRLTGGEPLIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQA
HHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEHHHH
RKLKSAGMRRITISLDTLRPDRFKAISQRGTHYKVIEGIEAVAAAGFTDTKLDSVVIRGF
HHHHHCCCEEEEEEEECCCCHHHHHHHHCCCEEHHHHHHHHHHHCCCCCCCCCCEEEECC
NDDELSDLIEFARNVNAEVRFIEYMDVGGATQWSMDKVFTKAQMLSTLGKKYGPIAALPK
CHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
YDSAPANRYRLPDGTTFGIIASTTEPFCATCDRSRLTADGIWLHCLYALSGINLRESVRA
CCCCCCCCEECCCCCEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHC
GASANDVVQILQRGWRDRANRGAEQRLAQRTRQVFLPVSRLKRDPHLEMHTRGG
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
>Mature Secondary Structure 
SRSGLCINESPIRDRCGRTMGDLRLSVIDQCNLRCRYCMPEAEYAWLPRADLLSVDEIS
CCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
LIVDAFIAVGVDKIRLTGGEPLIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQA
HHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEHHHH
RKLKSAGMRRITISLDTLRPDRFKAISQRGTHYKVIEGIEAVAAAGFTDTKLDSVVIRGF
HHHHHCCCEEEEEEEECCCCHHHHHHHHCCCEEHHHHHHHHHHHCCCCCCCCCCEEEECC
NDDELSDLIEFARNVNAEVRFIEYMDVGGATQWSMDKVFTKAQMLSTLGKKYGPIAALPK
CHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
YDSAPANRYRLPDGTTFGIIASTTEPFCATCDRSRLTADGIWLHCLYALSGINLRESVRA
CCCCCCCCEECCCCCEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHC
GASANDVVQILQRGWRDRANRGAEQRLAQRTRQVFLPVSRLKRDPHLEMHTRGG
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]