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The map label for this gene is hcr [C]

Identifier: 121639120

GI number: 121639120

Start: 3559594

End: 3560736

Strand: Reverse

Name: hcr [C]

Synonym: BCG_3260c

Alternate gene names: 121639120

Gene position: 3560736-3559594 (Counterclockwise)

Preceding gene: 121639121

Following gene: 121639119

Centisome position: 81.4

GC content: 66.75

Gene sequence:

>1143_bases
ATGAGCAAGAAACACACGACGCTTAACGCCAGCATCATCGACACCAGGCGCCCCACCGTCGCCGGAGCCGACCGGCATCC
GGGCTGGCATGCGCTGCGCAAGATTGCCGCGCGCATCACGACGCCATTGTTGCCCGACGACTACCTTCACCTGGCAAATC
CGCTGTGGTCCGCGCGGGAATTGCGGGGGCGCATCCTAGGGGTCCGCCGAGAGACGGAAGACTCCGCGACCCTGTTCATC
AAACCGGGCTGGGGCTTCAGTTTCGACTACCAGCCGGGCCAATACATCGGGATCGGGCTGCTGGTCGACGGGTGCTGGCG
CTGGCGGTCGTATTCGCTGACGTCGAGTCCGGCGGCATCCGGGTCCGCGCGCATGGTGACCGTCACGGTGAAGGCGATGC
CCGAGGGCTTCCTGTCCACCCACTTGGTGGCCGGGGTAAAGCCAGGGACCATTGTGCGGCTGGCTGCGCCCCAGGGCAAT
TTCGTATTACCGGATCCGGCGCCCCCGTTGATTCTGTTTTTGACTGCCGGGTCGGGGATTACGCCGGTAATGTCGATGCT
TCGAACGTTGGTGCGCCGCAACCAAATCACCGACGTAGTGCACCTGCATTCGGCGCCCACCGCAGCTGACGTGATGTTCG
GTGCCGAGCTGGCTGCCCTGGCGGCCGACCATCCCGGTTATCGGTTGTCGGTGCGCGAGACGCGCGCCCAGGGCCGGCTG
GACCTGACCCGGATCGGTCAGCAGGTGCCGGACTGGCGTGAACGCCAGACCTGGGCGTGCGGGCCGGAGGGCGTGCTCAA
CCAGGCCGACAAGGTCTGGTCATCGGCGGGTGCCAGCGACCGACTGCACCTGGAGCGGTTCGCAGTGTCCAAAACGGCGC
CCGCTGGAGCGGGCGGGACCGTCACGTTCGCCCGAAGTGGCAAGAGCGTAGCCGCCGATGCTGCCACGTCGTTGATGGAC
GCCGGTGAGGGCGCCGGCGTGCAGCTACCCTTCGGCTGCCGGATGGGCATCTGCCAGTCGTGTGTGGTCGACCTGGTGGA
AGGCCATGTTCGGGATCTGCGCACGGGCCAGCGGCATGAGCCCGGAACCCGGGTCCAGACCTGCGTGTCGGCCGCCTCGG
GTGATTGCGTGCTGGACATCTAG

Upstream 100 bases:

>100_bases
GGGTGTGACGCAGTCTGCGCGTCCGGGCCTAGATACGGAACCGTAGGTTACGGTACCGTAGCTTTGTTGGGCGGAAGCTA
AGGCCGAGCAGGAGCTTCCT

Downstream 100 bases:

>100_bases
TGTTACTCATAGGTAACCTACGGAATCGTAAGTTACGATAGCGTAGGTCATCGGCCGTATGACGCAGGGAGAAGACGATG
GCGATCACTGACGTCGACGT

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPDDYLHLANPLWSARELRGRILGVRRETEDSATLFI
KPGWGFSFDYQPGQYIGIGLLVDGCWRWRSYSLTSSPAASGSARMVTVTVKAMPEGFLSTHLVAGVKPGTIVRLAAPQGN
FVLPDPAPPLILFLTAGSGITPVMSMLRTLVRRNQITDVVHLHSAPTAADVMFGAELAALAADHPGYRLSVRETRAQGRL
DLTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGASDRLHLERFAVSKTAPAGAGGTVTFARSGKSVAADAATSLMD
AGEGAGVQLPFGCRMGICQSCVVDLVEGHVRDLRTGQRHEPGTRVQTCVSAASGDCVLDI

Sequences:

>Translated_380_residues
MSKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPDDYLHLANPLWSARELRGRILGVRRETEDSATLFI
KPGWGFSFDYQPGQYIGIGLLVDGCWRWRSYSLTSSPAASGSARMVTVTVKAMPEGFLSTHLVAGVKPGTIVRLAAPQGN
FVLPDPAPPLILFLTAGSGITPVMSMLRTLVRRNQITDVVHLHSAPTAADVMFGAELAALAADHPGYRLSVRETRAQGRL
DLTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGASDRLHLERFAVSKTAPAGAGGTVTFARSGKSVAADAATSLMD
AGEGAGVQLPFGCRMGICQSCVVDLVEGHVRDLRTGQRHEPGTRVQTCVSAASGDCVLDI
>Mature_379_residues
SKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPDDYLHLANPLWSARELRGRILGVRRETEDSATLFIK
PGWGFSFDYQPGQYIGIGLLVDGCWRWRSYSLTSSPAASGSARMVTVTVKAMPEGFLSTHLVAGVKPGTIVRLAAPQGNF
VLPDPAPPLILFLTAGSGITPVMSMLRTLVRRNQITDVVHLHSAPTAADVMFGAELAALAADHPGYRLSVRETRAQGRLD
LTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGASDRLHLERFAVSKTAPAGAGGTVTFARSGKSVAADAATSLMDA
GEGAGVQLPFGCRMGICQSCVVDLVEGHVRDLRTGQRHEPGTRVQTCVSAASGDCVLDI

Specific function: This is an electron transfer partner for desA3 [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=295, Percent_Identity=28.135593220339, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787658, Length=321, Percent_Identity=26.4797507788162, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788903, Length=218, Percent_Identity=28.4403669724771, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788104, Length=293, Percent_Identity=27.9863481228669, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323510, Length=192, Percent_Identity=27.0833333333333, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40742; Mature: 40611

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPDDYLHLANPLWSARE
CCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHH
LRGRILGVRRETEDSATLFIKPGWGFSFDYQPGQYIGIGLLVDGCWRWRSYSLTSSPAAS
HHHHEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECHHCCCCCCCCCCCCCC
GSARMVTVTVKAMPEGFLSTHLVAGVKPGTIVRLAAPQGNFVLPDPAPPLILFLTAGSGI
CCCEEEEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCEEEEEECCCCH
TPVMSMLRTLVRRNQITDVVHLHSAPTAADVMFGAELAALAADHPGYRLSVRETRAQGRL
HHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCC
DLTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGASDRLHLERFAVSKTAPAGAGGT
HHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCCCE
VTFARSGKSVAADAATSLMDAGEGAGVQLPFGCRMGICQSCVVDLVEGHVRDLRTGQRHE
EEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PGTRVQTCVSAASGDCVLDI
CCHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
SKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPDDYLHLANPLWSARE
CCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHH
LRGRILGVRRETEDSATLFIKPGWGFSFDYQPGQYIGIGLLVDGCWRWRSYSLTSSPAAS
HHHHEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECHHCCCCCCCCCCCCCC
GSARMVTVTVKAMPEGFLSTHLVAGVKPGTIVRLAAPQGNFVLPDPAPPLILFLTAGSGI
CCCEEEEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCEEEEEECCCCH
TPVMSMLRTLVRRNQITDVVHLHSAPTAADVMFGAELAALAADHPGYRLSVRETRAQGRL
HHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCC
DLTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGASDRLHLERFAVSKTAPAGAGGT
HHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCCCE
VTFARSGKSVAADAATSLMDAGEGAGVQLPFGCRMGICQSCVVDLVEGHVRDLRTGQRHE
EEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PGTRVQTCVSAASGDCVLDI
CCHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]