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The map label for this gene is fadE24 [H]

Identifier: 121639022

GI number: 121639022

Start: 3458410

End: 3459816

Strand: Direct

Name: fadE24 [H]

Synonym: BCG_3162

Alternate gene names: 121639022

Gene position: 3458410-3459816 (Clockwise)

Preceding gene: 121639021

Following gene: 121639023

Centisome position: 79.06

GC content: 67.09

Gene sequence:

>1407_bases
ATGACCAACACCACCTCTGCTGCAAATGCTGCAAAACCCTCCGGCGCACGCACCGATAGACGCGGCCGCACGACCGGTGT
CGGCCTGGCGCCCCACAAACGGACCGGCATCGACGTCGCACTGGCGCTGCTAACCCCGATTGTCGGCCAGGAGTTCCTGG
ACAAATACCGCCTGCGCGATCCGCTGAACCGATCACTGCGCTACGGCGTGAAGACGATGTTTGCCACTGCCGGCGCCGCC
ACCCGTCAGTTCCAGCGGGTGCAAGGCCTGCGGGGCGGACCGACCCGGCTGAAGTCCAGCGGCCGAGACTACTTCGATCT
GACGCCCGATGACGACCAGAAGCTGATCATCGAGACCGTCGACGAATTCGCCGAAGAGGTACTGCGACCCGCCGCGCACG
ACGCCGACGACGCCGCGACCTACCCGTCCGACTTGACCGCCAAGGCCGCCGAGCTGGGCATTACCGCGATCAACATCCCC
GAGGACTTCGACGGTATCGCCGAACACCGCTCCAGCGTCACCAACGTGCTGGTGGCTGAGGCACTGGCGTATGGCGACAT
GGGCCTGGCACTGCCGATCCTGGCGCCTGGCGGGGTGGCGTCCGCGCTCACCCATTGGGGCAGCGCCGATCAGCAGGCCA
CCTATCTCAAAGAGTTCGCCGGCGAGAACGTTCCGCAGGCCTGCGTGGCCATCACCGAACCGCAGCCACTATTCGATCCC
ACCCGGCTGAAGACCACCGCGGTGCGCACCCCGTCCGGTTACCGGCTCGACGGCGTGAAGTCGTTGATCCCGGCCGCCGC
CGACGCCGAGCTGTTTATTGTCGGCGCGCAGCTGGGCGGCAAGCCCGCACTGTTCATTGTCGAGTCCGCGGCCAGCGGCC
TGACCGTCAAGGCGGATCCGAGCATGGGGATTCGCGGCGCGGCGTTGGGCCAGGTCGAACTCTGCGGGGTGTCGGTCCCG
CTTAACGCCCGGCTGGGCGAGGACGAAGCCAGCGACAACGACTATTCCGAGGCGCTTGCGCTGGCCCGGTTGGGTTGGGC
GGCGCTGGCGGTCGGTACCTCTCACGCCGTGCTCGACTACGTCGTCCCGTATGTGAAACAACGCCAGGCTTTCGGCGAGC
CGATCGCTCATCGCCAAGCGGTGGCGTTCATGTGCGCCAACATCGCGATCGAGCTCGACGGCCTGCGCCTGATCACCTGG
CGCGGGGCGTCCCGTGCCGAGCAGGGTCTGCCGTTCGCAAGGGAAGCGGCGCTAGCCAAGCGGCTTGGCTCCGACAAGGG
CATGCAGATCGGCCTGGACGGGGTGCAACTGCTGGGCGGCCACGGCTACACCAAGGAGCATCCGGTTGAGCGCTGGTACC
GCGACCTGCGAGCCATCGGCGTCGCCGAGGGCGTTGTTGTCATCTAG

Upstream 100 bases:

>100_bases
ACCAGCTTGTCCCGGATGTGAACAACTTAACAAGCACCCCTATCTTACTCCGGAGTAAGATAGGGTGGTCCGCTATCACC
CCGATGACCGAGGCTGCCGT

Downstream 100 bases:

>100_bases
AACGAGCTGAAAGATCAATCATGGCAATAAATCTGGAACTGCCGCGCAAGCTGCAGGCGATCATCGTCAAGACCCATCAG
GGCGCTGCGGAGATGATGCG

Product: putative acyl-CoA dehydrogenase fadE24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MTNTTSAANAAKPSGARTDRRGRTTGVGLAPHKRTGIDVALALLTPIVGQEFLDKYRLRDPLNRSLRYGVKTMFATAGAA
TRQFQRVQGLRGGPTRLKSSGRDYFDLTPDDDQKLIIETVDEFAEEVLRPAAHDADDAATYPSDLTAKAAELGITAINIP
EDFDGIAEHRSSVTNVLVAEALAYGDMGLALPILAPGGVASALTHWGSADQQATYLKEFAGENVPQACVAITEPQPLFDP
TRLKTTAVRTPSGYRLDGVKSLIPAAADAELFIVGAQLGGKPALFIVESAASGLTVKADPSMGIRGAALGQVELCGVSVP
LNARLGEDEASDNDYSEALALARLGWAALAVGTSHAVLDYVVPYVKQRQAFGEPIAHRQAVAFMCANIAIELDGLRLITW
RGASRAEQGLPFAREAALAKRLGSDKGMQIGLDGVQLLGGHGYTKEHPVERWYRDLRAIGVAEGVVVI

Sequences:

>Translated_468_residues
MTNTTSAANAAKPSGARTDRRGRTTGVGLAPHKRTGIDVALALLTPIVGQEFLDKYRLRDPLNRSLRYGVKTMFATAGAA
TRQFQRVQGLRGGPTRLKSSGRDYFDLTPDDDQKLIIETVDEFAEEVLRPAAHDADDAATYPSDLTAKAAELGITAINIP
EDFDGIAEHRSSVTNVLVAEALAYGDMGLALPILAPGGVASALTHWGSADQQATYLKEFAGENVPQACVAITEPQPLFDP
TRLKTTAVRTPSGYRLDGVKSLIPAAADAELFIVGAQLGGKPALFIVESAASGLTVKADPSMGIRGAALGQVELCGVSVP
LNARLGEDEASDNDYSEALALARLGWAALAVGTSHAVLDYVVPYVKQRQAFGEPIAHRQAVAFMCANIAIELDGLRLITW
RGASRAEQGLPFAREAALAKRLGSDKGMQIGLDGVQLLGGHGYTKEHPVERWYRDLRAIGVAEGVVVI
>Mature_467_residues
TNTTSAANAAKPSGARTDRRGRTTGVGLAPHKRTGIDVALALLTPIVGQEFLDKYRLRDPLNRSLRYGVKTMFATAGAAT
RQFQRVQGLRGGPTRLKSSGRDYFDLTPDDDQKLIIETVDEFAEEVLRPAAHDADDAATYPSDLTAKAAELGITAINIPE
DFDGIAEHRSSVTNVLVAEALAYGDMGLALPILAPGGVASALTHWGSADQQATYLKEFAGENVPQACVAITEPQPLFDPT
RLKTTAVRTPSGYRLDGVKSLIPAAADAELFIVGAQLGGKPALFIVESAASGLTVKADPSMGIRGAALGQVELCGVSVPL
NARLGEDEASDNDYSEALALARLGWAALAVGTSHAVLDYVVPYVKQRQAFGEPIAHRQAVAFMCANIAIELDGLRLITWR
GASRAEQGLPFAREAALAKRLGSDKGMQIGLDGVQLLGGHGYTKEHPVERWYRDLRAIGVAEGVVVI

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=29.1005291005291, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI4501859, Length=366, Percent_Identity=28.9617486338798, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=28.8770053475936, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=28.8770053475936, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI226958412, Length=366, Percent_Identity=27.0491803278689, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI76496475, Length=367, Percent_Identity=28.0653950953678, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4557235, Length=367, Percent_Identity=28.0653950953678, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI7656849, Length=363, Percent_Identity=25.8953168044077, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI226958414, Length=331, Percent_Identity=27.4924471299094, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI4501857, Length=384, Percent_Identity=27.0833333333333, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI21361497, Length=366, Percent_Identity=25.4098360655738, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4503943, Length=396, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI7669494, Length=396, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI87081958, Length=366, Percent_Identity=26.775956284153, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786223, Length=367, Percent_Identity=25.8855585831063, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17569725, Length=373, Percent_Identity=31.3672922252011, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17534899, Length=373, Percent_Identity=31.9034852546917, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17506239, Length=362, Percent_Identity=29.2817679558011, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17508101, Length=361, Percent_Identity=29.3628808864266, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17570075, Length=397, Percent_Identity=28.9672544080605, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17533517, Length=363, Percent_Identity=24.7933884297521, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71990804, Length=285, Percent_Identity=28.0701754385965, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17534353, Length=374, Percent_Identity=24.331550802139, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=376, Percent_Identity=25.2659574468085, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=367, Percent_Identity=24.2506811989101, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=233, Percent_Identity=28.755364806867, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=270, Percent_Identity=26.2962962962963, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=360, Percent_Identity=21.9444444444444, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24666513, Length=363, Percent_Identity=30.8539944903581, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=30.6451612903226, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24660351, Length=374, Percent_Identity=31.5508021390374, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24646207, Length=367, Percent_Identity=28.3378746594005, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI21355753, Length=372, Percent_Identity=27.4193548387097, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281363737, Length=383, Percent_Identity=26.1096605744125, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI19920834, Length=270, Percent_Identity=27.4074074074074, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 49647; Mature: 49516

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTTSAANAAKPSGARTDRRGRTTGVGLAPHKRTGIDVALALLTPIVGQEFLDKYRLRD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
PLNRSLRYGVKTMFATAGAATRQFQRVQGLRGGPTRLKSSGRDYFDLTPDDDQKLIIETV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCEECCCCCCCCHHHHHHH
DEFAEEVLRPAAHDADDAATYPSDLTAKAAELGITAINIPEDFDGIAEHRSSVTNVLVAE
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHH
ALAYGDMGLALPILAPGGVASALTHWGSADQQATYLKEFAGENVPQACVAITEPQPLFDP
HHHHCCCCCEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHEEECCCCCCCCC
TRLKTTAVRTPSGYRLDGVKSLIPAAADAELFIVGAQLGGKPALFIVESAASGLTVKADP
CCCEEEEEECCCCCEECCHHHHCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCEEEECC
SMGIRGAALGQVELCGVSVPLNARLGEDEASDNDYSEALALARLGWAALAVGTSHAVLDY
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
VVPYVKQRQAFGEPIAHRQAVAFMCANIAIELDGLRLITWRGASRAEQGLPFAREAALAK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECCEEEEEECCCCHHHHCCCHHHHHHHHH
RLGSDKGMQIGLDGVQLLGGHGYTKEHPVERWYRDLRAIGVAEGVVVI
HHCCCCCCEECCCHHHEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEC
>Mature Secondary Structure 
TNTTSAANAAKPSGARTDRRGRTTGVGLAPHKRTGIDVALALLTPIVGQEFLDKYRLRD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
PLNRSLRYGVKTMFATAGAATRQFQRVQGLRGGPTRLKSSGRDYFDLTPDDDQKLIIETV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCEECCCCCCCCHHHHHHH
DEFAEEVLRPAAHDADDAATYPSDLTAKAAELGITAINIPEDFDGIAEHRSSVTNVLVAE
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHH
ALAYGDMGLALPILAPGGVASALTHWGSADQQATYLKEFAGENVPQACVAITEPQPLFDP
HHHHCCCCCEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHEEECCCCCCCCC
TRLKTTAVRTPSGYRLDGVKSLIPAAADAELFIVGAQLGGKPALFIVESAASGLTVKADP
CCCEEEEEECCCCCEECCHHHHCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCEEEECC
SMGIRGAALGQVELCGVSVPLNARLGEDEASDNDYSEALALARLGWAALAVGTSHAVLDY
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
VVPYVKQRQAFGEPIAHRQAVAFMCANIAIELDGLRLITWRGASRAEQGLPFAREAALAK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECCEEEEEECCCCHHHHCCCHHHHHHHHH
RLGSDKGMQIGLDGVQLLGGHGYTKEHPVERWYRDLRAIGVAEGVVVI
HHCCCCCCEECCCHHHEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]