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The map label for this gene is moaC

Identifier: 121638996

GI number: 121638996

Start: 3433658

End: 3434170

Strand: Direct

Name: moaC

Synonym: BCG_3136

Alternate gene names: 121638996

Gene position: 3433658-3434170 (Clockwise)

Preceding gene: 121638995

Following gene: 121638997

Centisome position: 78.49

GC content: 58.28

Gene sequence:

>513_bases
ATGATCGACCATGCACTCGCGCTGACACATATCGATGAGCGTGGTGCGGCACGAATGGTCGATGTGTCCGAGAAACCCGT
GACTTTGAGGGTTGCCAAAGCGTCAGGGCTCGTGATCATGAAGCCGTCTACCTTGAGGATGATTTCCGACGGTGCCGCTG
CTAAGGGTGACGTCATGGCGGCGGCCCGGATAGCTGGCATCGCGGCGGCGAAACGTACGGGTGATCTTATTCCGCTATGC
CACCCGTTAGGGCTCGACGCTGTCAGCGTCACTATCACGCCGTGCGAGCCTGACCGGGTGAAGATTCTGGCGACAACCAC
CACGCTGGGGCGTACCGGCGTGGAAATGGAAGCGTTGACCGCAGTTTCAGTCGCCGCCTTGACTATCTACGACATGTGCA
AAGCCGTCGATCGAGCCATGGAGATTTCTCAGATCGTGCTCCAAGAGAAAAGCGGCGGCCGGTCCGGAGTTTATCGCCGA
AGTGCTTCTGATTTGGCCTGTCAGTCCCGATAA

Upstream 100 bases:

>100_bases
CGTGGACGCGCAAGCTGGGCTATCTGACCGACATCGACTTCGATCTTGCGGCGTCCGTCGAGGCGATGTATGCGACAGAA
TTCGCTGACAGGCCAGCACG

Downstream 100 bases:

>100_bases
GTAGGTGAGTGTCTGAATGATTAAAGTGAATGTTCTTTACTTCGGTGCCGTTCGTGAGGCGTGTGACGAAACGCCTCGGG
AGGAAGTAGAGGTTCAGAAC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MIDHALALTHIDERGAARMVDVSEKPVTLRVAKASGLVIMKPSTLRMISDGAAAKGDVMAAARIAGIAAAKRTGDLIPLC
HPLGLDAVSVTITPCEPDRVKILATTTTLGRTGVEMEALTAVSVAALTIYDMCKAVDRAMEISQIVLQEKSGGRSGVYRR
SASDLACQSR

Sequences:

>Translated_170_residues
MIDHALALTHIDERGAARMVDVSEKPVTLRVAKASGLVIMKPSTLRMISDGAAAKGDVMAAARIAGIAAAKRTGDLIPLC
HPLGLDAVSVTITPCEPDRVKILATTTTLGRTGVEMEALTAVSVAALTIYDMCKAVDRAMEISQIVLQEKSGGRSGVYRR
SASDLACQSR
>Mature_170_residues
MIDHALALTHIDERGAARMVDVSEKPVTLRVAKASGLVIMKPSTLRMISDGAAAKGDVMAAARIAGIAAAKRTGDLIPLC
HPLGLDAVSVTITPCEPDRVKILATTTTLGRTGVEMEALTAVSVAALTIYDMCKAVDRAMEISQIVLQEKSGGRSGVYRR
SASDLACQSR

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=58.2278481012658, Blast_Score=164, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=45.6375838926174, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28574490, Length=158, Percent_Identity=49.3670886075949, Blast_Score=143, Evalue=5e-35,
Organism=Drosophila melanogaster, GI28574492, Length=147, Percent_Identity=48.9795918367347, Blast_Score=130, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC1_MYCBO (P0A5K5)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856783.1
- ProteinModelPortal:   P0A5K5
- SMR:   P0A5K5
- EnsemblBacteria:   EBMYCT00000017318
- GeneID:   1092945
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3138
- GeneTree:   EBGT00050000016668
- HOGENOM:   HBG605231
- OMA:   RIKEGTI
- ProtClustDB:   PRK09364
- BioCyc:   MBOV233413:MB3138-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17845; Mature: 17845

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: ACT_SITE 131-131

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDHALALTHIDERGAARMVDVSEKPVTLRVAKASGLVIMKPSTLRMISDGAAAKGDVMA
CCCCEEEEEEECCCCCEEEEECCCCCEEEEEECCCCEEEECCCCEEEECCCCCCCCCHHH
AARIAGIAAAKRTGDLIPLCHPLGLDAVSVTITPCEPDRVKILATTTTLGRTGVEMEALT
HHHHHHHHHHHCCCCCCEECCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHH
AVSVAALTIYDMCKAVDRAMEISQIVLQEKSGGRSGVYRRSASDLACQSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCC
>Mature Secondary Structure
MIDHALALTHIDERGAARMVDVSEKPVTLRVAKASGLVIMKPSTLRMISDGAAAKGDVMA
CCCCEEEEEEECCCCCEEEEECCCCCEEEEEECCCCEEEECCCCEEEECCCCCCCCCHHH
AARIAGIAAAKRTGDLIPLCHPLGLDAVSVTITPCEPDRVKILATTTTLGRTGVEMEALT
HHHHHHHHHHHCCCCCCEECCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCHHHHH
AVSVAALTIYDMCKAVDRAMEISQIVLQEKSGGRSGVYRRSASDLACQSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972