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The map label for this gene is moaA1 [H]

Identifier: 121638994

GI number: 121638994

Start: 3432136

End: 3433215

Strand: Direct

Name: moaA1 [H]

Synonym: BCG_3134

Alternate gene names: 121638994

Gene position: 3432136-3433215 (Clockwise)

Preceding gene: 121638993

Following gene: 121638995

Centisome position: 78.46

GC content: 55.09

Gene sequence:

>1080_bases
ATGAGTACGCCTACGCTGCCTGATATGGTAGCTCCATCCCCGAGAGTGCGAGTAAAAGACCGTTGTCGCCGGATGATGGG
GGACCTACGCCTTTCCGTTATCGATCAGTGCAATTTGCGATGCCGTTATTGTATGCCCGAAGAGCACTACACATGGTTGC
CGCGGCAAGATTTGCTATCCGTCAAAGAAATCAGCGCCATTGTAGATGTTTTCCTTTCCGTTGGGGTAAGTAAAGTTCGA
ATCACCGGTGGCGAACCGCTGATCCGCCCAGATTTGCCGGAAATAGTGAGGACATTGAGCGCAAAGGTCGGCGAAGATTC
AGGTCTGAGAGACTTAGCGATCACGACGAACGGCGTCCTTCTCGCCGACCGCGTTGACGGCCTGAAGGCTGCGGGTATGA
AACGCATCACTGTCAGTCTTGATACGTTGCAACCCGAGCGCTTCAAGGCGATAAGTCAGCGTAATAGCCACGATAAGGTC
ATCGCGGGTATCAAGGCTGTCGCAGCCGCGGGATTTACGGACACAAAAATAGACACAACGGTGATGCGTGGTGCCAATCA
CGATGAGCTGGCTGATCTGATCGAATTCGCTCGGACTGTTAACGCGGAAGTCAGGTTCATTGAGTACATGGACGTCGGCG
GCGCAACTCACTGGGCATGGGAGAAGGTCTTTACCAAAGCGAACATGCTCGAGTCCCTTGAGAAACGGTATGGACGTATT
GAGCCTTTGCCCAAACATGATACGGCGCCCGCCAATCGATATGCGCTTCCGGACGGAACTACCTTCGGAATTATCGCGTC
GACAACGGAGCCATTCTGCGCAACCTGTGACCGTTCACGGTTGACCGCCGATGGCTTATGGCTGCATTGCTTGTACGCAA
TATCGGGTATCAACCTAAGGGAGCCGCTGCGTGCAGGCGCGACTCACGATGACTTGGTGGAAACCGTGACAACCGGATGG
CGGCGACGAACGGATCGCGGAGCAGAGCAGCGTCTTGCCCAACGCGAGCGCGGAGTGTTCCTGCCATTAAGCACGTTAAA
GGCCGACCCGCATCTGGAGATGCACACCAGGGGCGGGTAA

Upstream 100 bases:

>100_bases
GCATTTCGGTAACGATTGTTAGTTAACCCTTGTACGAAACTCTCTTGAGGCGCTTTAACCGACTGCGTCCAAAGTGGAGG
ATCGAAAAGATGATAGGAAA

Downstream 100 bases:

>100_bases
GCCGAACGAACAGTCGATTGATCAACGACTCCACAGTTGAGGAAGGAACCATGACGGTCAGCACCCCTGAGCAACACGAG
CAACGAGCATCCCACGATGC

Product: putative molybdenum cofactor biosynthesis protein A moaA1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSTPTLPDMVAPSPRVRVKDRCRRMMGDLRLSVIDQCNLRCRYCMPEEHYTWLPRQDLLSVKEISAIVDVFLSVGVSKVR
ITGGEPLIRPDLPEIVRTLSAKVGEDSGLRDLAITTNGVLLADRVDGLKAAGMKRITVSLDTLQPERFKAISQRNSHDKV
IAGIKAVAAAGFTDTKIDTTVMRGANHDELADLIEFARTVNAEVRFIEYMDVGGATHWAWEKVFTKANMLESLEKRYGRI
EPLPKHDTAPANRYALPDGTTFGIIASTTEPFCATCDRSRLTADGLWLHCLYAISGINLREPLRAGATHDDLVETVTTGW
RRRTDRGAEQRLAQRERGVFLPLSTLKADPHLEMHTRGG

Sequences:

>Translated_359_residues
MSTPTLPDMVAPSPRVRVKDRCRRMMGDLRLSVIDQCNLRCRYCMPEEHYTWLPRQDLLSVKEISAIVDVFLSVGVSKVR
ITGGEPLIRPDLPEIVRTLSAKVGEDSGLRDLAITTNGVLLADRVDGLKAAGMKRITVSLDTLQPERFKAISQRNSHDKV
IAGIKAVAAAGFTDTKIDTTVMRGANHDELADLIEFARTVNAEVRFIEYMDVGGATHWAWEKVFTKANMLESLEKRYGRI
EPLPKHDTAPANRYALPDGTTFGIIASTTEPFCATCDRSRLTADGLWLHCLYAISGINLREPLRAGATHDDLVETVTTGW
RRRTDRGAEQRLAQRERGVFLPLSTLKADPHLEMHTRGG
>Mature_358_residues
STPTLPDMVAPSPRVRVKDRCRRMMGDLRLSVIDQCNLRCRYCMPEEHYTWLPRQDLLSVKEISAIVDVFLSVGVSKVRI
TGGEPLIRPDLPEIVRTLSAKVGEDSGLRDLAITTNGVLLADRVDGLKAAGMKRITVSLDTLQPERFKAISQRNSHDKVI
AGIKAVAAAGFTDTKIDTTVMRGANHDELADLIEFARTVNAEVRFIEYMDVGGATHWAWEKVFTKANMLESLEKRYGRIE
PLPKHDTAPANRYALPDGTTFGIIASTTEPFCATCDRSRLTADGLWLHCLYAISGINLREPLRAGATHDDLVETVTTGWR
RRTDRGAEQRLAQRERGVFLPLSTLKADPHLEMHTRGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=311, Percent_Identity=37.9421221864952, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI22027536, Length=311, Percent_Identity=37.9421221864952, Blast_Score=228, Evalue=5e-60,
Organism=Escherichia coli, GI1786999, Length=332, Percent_Identity=32.2289156626506, Blast_Score=174, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17561210, Length=304, Percent_Identity=35.8552631578947, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI32566331, Length=312, Percent_Identity=34.2948717948718, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI32566329, Length=304, Percent_Identity=34.5394736842105, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI28574490, Length=303, Percent_Identity=36.6336633663366, Blast_Score=197, Evalue=8e-51,
Organism=Drosophila melanogaster, GI28574488, Length=302, Percent_Identity=36.7549668874172, Blast_Score=197, Evalue=9e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 39960; Mature: 39829

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPTLPDMVAPSPRVRVKDRCRRMMGDLRLSVIDQCNLRCRYCMPEEHYTWLPRQDLLS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHH
VKEISAIVDVFLSVGVSKVRITGGEPLIRPDLPEIVRTLSAKVGEDSGLRDLAITTNGVL
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEE
LADRVDGLKAAGMKRITVSLDTLQPERFKAISQRNSHDKVIAGIKAVAAAGFTDTKIDTT
EEECCCCHHHCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHH
VMRGANHDELADLIEFARTVNAEVRFIEYMDVGGATHWAWEKVFTKANMLESLEKRYGRI
HHCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
EPLPKHDTAPANRYALPDGTTFGIIASTTEPFCATCDRSRLTADGLWLHCLYAISGINLR
CCCCCCCCCCCCCEECCCCCEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCHH
EPLRAGATHDDLVETVTTGWRRRTDRGAEQRLAQRERGVFLPLSTLKADPHLEMHTRGG
HHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEHHHCCCCCCEEEECCCC
>Mature Secondary Structure 
STPTLPDMVAPSPRVRVKDRCRRMMGDLRLSVIDQCNLRCRYCMPEEHYTWLPRQDLLS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHH
VKEISAIVDVFLSVGVSKVRITGGEPLIRPDLPEIVRTLSAKVGEDSGLRDLAITTNGVL
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEE
LADRVDGLKAAGMKRITVSLDTLQPERFKAISQRNSHDKVIAGIKAVAAAGFTDTKIDTT
EEECCCCHHHCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHH
VMRGANHDELADLIEFARTVNAEVRFIEYMDVGGATHWAWEKVFTKANMLESLEKRYGRI
HHCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
EPLPKHDTAPANRYALPDGTTFGIIASTTEPFCATCDRSRLTADGLWLHCLYAISGINLR
CCCCCCCCCCCCCEECCCCCEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCHH
EPLRAGATHDDLVETVTTGWRRRTDRGAEQRLAQRERGVFLPLSTLKADPHLEMHTRGG
HHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEHHHCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]