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The map label for this gene is pknE [H]

Identifier: 121638850

GI number: 121638850

Start: 3277871

End: 3278638

Strand: Reverse

Name: pknE [H]

Synonym: BCG_2990c

Alternate gene names: 121638850

Gene position: 3278638-3277871 (Counterclockwise)

Preceding gene: 121638851

Following gene: 121638849

Centisome position: 74.95

GC content: 63.28

Gene sequence:

>768_bases
GTGGCCGACAAATCCAAACGCCCCCCGCGATTCGATCTGAAGTCCGCCGACGGCAGCTTCGGCCGGCTCGTCCAGATTGG
TGGCACCACCATCGTCGTCGTTTTTGCCGTCGTCCTGGTCTTCTACATCGTGACGTCGCGCGACGACAAGAAGGACGGCG
TCGCGGGCCCCGGCGATGCAGTACGGGTGACGTCGAGCAAGCTGGTCACCCAGCCCGGAACCAGCAACCCCAAGGCCGTG
GTGTCCTTCTACGAGGATTTCCTGTGTCCGGCGTGCGGCATATTCGAGCGCGGTTTCGGGCCAACCGTGTCCAAGCTCGT
GGACATCGGCGCTGTCGCGGCCGATTACACGATGGTGGCCATTCTCGATAGCGCCAGCAATCAACACTATTCGTCGCGAG
CGGCTGCTGCGGCTTATTGCGTTGCCGACGAATCGATCGAGGCGTTCCGCCGCTTCCACGCCGCCTTGTTCAGCAAGGAC
ATCCAGCCTGCCGAGCTCGGCAAGGATTTCCCCGACAACGCGCGGTTGATCGAACTTGCCCGCGAAGCCGGCGTCGTGGG
CAAGGTGCCCGACTGCATCAACAGCGGCAAGTACATCGAAAAAGTCGACGGGCTGGCGGCGGCGGTCAACGTGCACGCGA
CCCCGACGGTCCGGGTCAATGGCACAGAGTACGAGTGGTCGACGCCGGCGGCGCTGGTCGCCAAGATCAAAGAAATTGTG
GGTGATGTGCCGGGCATTGACTCGGCCGCTGCTACCGCGACATCCTGA

Upstream 100 bases:

>100_bases
TTGAGTCGAGGCTGGCTTGCCGCCGGTACGCTAGAGGCGCCGTCGCCTGACCGCGGCCGCGACAAGCCGACAAATCGAGC
ACGTGAGGATCAGCGAAACT

Downstream 100 bases:

>100_bases
CGATTGTGGTGGCAGCTCGACCTGCCGAGCGATCCGGCGACCCGGCTGCGGTGCGGGTGCCGGTGCCTAGCGCGTGGTGG
GTGCTGATCGGCGGTGTGAT

Product: putative membrane or secreted protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MADKSKRPPRFDLKSADGSFGRLVQIGGTTIVVVFAVVLVFYIVTSRDDKKDGVAGPGDAVRVTSSKLVTQPGTSNPKAV
VSFYEDFLCPACGIFERGFGPTVSKLVDIGAVAADYTMVAILDSASNQHYSSRAAAAAYCVADESIEAFRRFHAALFSKD
IQPAELGKDFPDNARLIELAREAGVVGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEWSTPAALVAKIKEIV
GDVPGIDSAAATATS

Sequences:

>Translated_255_residues
MADKSKRPPRFDLKSADGSFGRLVQIGGTTIVVVFAVVLVFYIVTSRDDKKDGVAGPGDAVRVTSSKLVTQPGTSNPKAV
VSFYEDFLCPACGIFERGFGPTVSKLVDIGAVAADYTMVAILDSASNQHYSSRAAAAAYCVADESIEAFRRFHAALFSKD
IQPAELGKDFPDNARLIELAREAGVVGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEWSTPAALVAKIKEIV
GDVPGIDSAAATATS
>Mature_254_residues
ADKSKRPPRFDLKSADGSFGRLVQIGGTTIVVVFAVVLVFYIVTSRDDKKDGVAGPGDAVRVTSSKLVTQPGTSNPKAVV
SFYEDFLCPACGIFERGFGPTVSKLVDIGAVAADYTMVAILDSASNQHYSSRAAAAAYCVADESIEAFRRFHAALFSKDI
QPAELGKDFPDNARLIELAREAGVVGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEWSTPAALVAKIKEIVG
DVPGIDSAAATATS

Specific function: Unknown

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 26862; Mature: 26730

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKSKRPPRFDLKSADGSFGRLVQIGGTTIVVVFAVVLVFYIVTSRDDKKDGVAGPGDA
CCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
VRVTSSKLVTQPGTSNPKAVVSFYEDFLCPACGIFERGFGPTVSKLVDIGAVAADYTMVA
EEEECCCEEECCCCCCHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEE
ILDSASNQHYSSRAAAAAYCVADESIEAFRRFHAALFSKDIQPAELGKDFPDNARLIELA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHH
REAGVVGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEWSTPAALVAKIKEIV
HHCCCCCCCHHHHCCCCHHHHHCCHHEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHH
GDVPGIDSAAATATS
CCCCCCCCCHHCCCC
>Mature Secondary Structure 
ADKSKRPPRFDLKSADGSFGRLVQIGGTTIVVVFAVVLVFYIVTSRDDKKDGVAGPGDA
CCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
VRVTSSKLVTQPGTSNPKAVVSFYEDFLCPACGIFERGFGPTVSKLVDIGAVAADYTMVA
EEEECCCEEECCCCCCHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEE
ILDSASNQHYSSRAAAAAYCVADESIEAFRRFHAALFSKDIQPAELGKDFPDNARLIELA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHH
REAGVVGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEWSTPAALVAKIKEIV
HHCCCCCCCHHHHCCCCHHHHHCCHHEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHH
GDVPGIDSAAATATS
CCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]