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The map label for this gene is nicT [H]

Identifier: 121638736

GI number: 121638736

Start: 3120616

End: 3121734

Strand: Direct

Name: nicT [H]

Synonym: BCG_2876

Alternate gene names: 121638736

Gene position: 3120616-3121734 (Clockwise)

Preceding gene: 121638735

Following gene: 121638737

Centisome position: 71.34

GC content: 63.36

Gene sequence:

>1119_bases
ATGGCCAGCAGCCAGCTCGACAGGCAGAGGTCGCGGTCGGCCAAAATGAACCGCGCTCTGACAGCAGCAGAATGGTGGCG
TCTGGGCCTGATGTTCGCGGTGATCGTCGCCTTGCATCTGGTTGGCTGGCTCACCGTGACGCTCTTGGTGGAGCCCGCGC
GGCTCAGCTTGGGCGGCAAGGCATTCGGCATCGGCGTCGGGCTGACGGCGTACACGCTGGGCTTACGGCACGCGTTCGAC
GCCGACCACATCGCCGCCATCGACAACACCACCCGCAAGCTGATGAGCGACGGACACCGACCCCTTGCCGTCGGGTTCTT
CTTTTCACTGGGCCACTCCACGGTGGTCTTCGGGCTGGCGGTAATGCTGGTGACCGGACTCAAGGCTATCGTCGGACCGG
TCGAGAACGACTCCTCGACGCTGCATCACTACACAGGCTTGATCGGTACCAGCATTTCCGGCGCGTTCCTGTATTTGATC
GGCATCCTCAACGTCATCGTCCTGGTCGGCATCGTGCGTGTCTTCGCCCACCTGCGCCGCGGCGACTACGACGAAGCCGA
ACTCGAACAGCAGTTGGACAACCGCGGACTGCTCATCCGGTTCCTCGGCCGCTTCACCAAGTCACTCACCAAGTCCTGGC
ATATGTACCCGGTCGGATTTTTGTTCGGTCTCGGGTTCGACACCGCCACCGAGATCGCGCTGTTGGTGCTGGCGGGAACC
AGTGCCGCGGCCGGCCTGCCCTGGTATGCCATCCTGTGCCTGCCCGTCTTGTTCGCCGCCGGCATGTGTCTGCTGGACAC
CATCGACGGTTCGTTCATGAATTTCGCGTACGGCTGGGCCTTCTCCAGCCCCGTGCGCAAGATCTACTACAACATCACCG
TCACCGGACTGTCGGTGGCAGTCGCACTGTTGATTGGCAGCGTTGAGCTGCTGGGCCTGATCGCCAACCAGTTGGGTTGG
CAGGGCCCGTTCTGGGACTGGCTTGGCGGCCTCGACCTCAACACCGTCGGCTTCGTCGTCGTCGCGATGTTCGCGCTCAC
CTGGGCCATTGCCCTGCTGGTCTGGCACTACGGCCGCGTTGAAGAGCGGTGGACCCCGGCGCCCGACCGCACAACTTGA

Upstream 100 bases:

>100_bases
ACCGCAACGGCGAGCCGTCGTCCGGCAAGCGATTTGCATCCCGTCAGCGCCTTACCTACAGTCGGGACATCGCGTTCTGC
CCCGTGCTGGAAGGACCGAC

Downstream 100 bases:

>100_bases
CCTCGGGCGATCAACCCTAGGGCGGTGCCGCCGGAATCGAGACGGTAGCCAAGCGAGCGGTCGACGTGTTGGAAAAGATC
TTCGCCGAGAACGATGTCCG

Product: putative nickel-transport integral membrane protein nicT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MASSQLDRQRSRSAKMNRALTAAEWWRLGLMFAVIVALHLVGWLTVTLLVEPARLSLGGKAFGIGVGLTAYTLGLRHAFD
ADHIAAIDNTTRKLMSDGHRPLAVGFFFSLGHSTVVFGLAVMLVTGLKAIVGPVENDSSTLHHYTGLIGTSISGAFLYLI
GILNVIVLVGIVRVFAHLRRGDYDEAELEQQLDNRGLLIRFLGRFTKSLTKSWHMYPVGFLFGLGFDTATEIALLVLAGT
SAAAGLPWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSSPVRKIYYNITVTGLSVAVALLIGSVELLGLIANQLGW
QGPFWDWLGGLDLNTVGFVVVAMFALTWAIALLVWHYGRVEERWTPAPDRTT

Sequences:

>Translated_372_residues
MASSQLDRQRSRSAKMNRALTAAEWWRLGLMFAVIVALHLVGWLTVTLLVEPARLSLGGKAFGIGVGLTAYTLGLRHAFD
ADHIAAIDNTTRKLMSDGHRPLAVGFFFSLGHSTVVFGLAVMLVTGLKAIVGPVENDSSTLHHYTGLIGTSISGAFLYLI
GILNVIVLVGIVRVFAHLRRGDYDEAELEQQLDNRGLLIRFLGRFTKSLTKSWHMYPVGFLFGLGFDTATEIALLVLAGT
SAAAGLPWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSSPVRKIYYNITVTGLSVAVALLIGSVELLGLIANQLGW
QGPFWDWLGGLDLNTVGFVVVAMFALTWAIALLVWHYGRVEERWTPAPDRTT
>Mature_371_residues
ASSQLDRQRSRSAKMNRALTAAEWWRLGLMFAVIVALHLVGWLTVTLLVEPARLSLGGKAFGIGVGLTAYTLGLRHAFDA
DHIAAIDNTTRKLMSDGHRPLAVGFFFSLGHSTVVFGLAVMLVTGLKAIVGPVENDSSTLHHYTGLIGTSISGAFLYLIG
ILNVIVLVGIVRVFAHLRRGDYDEAELEQQLDNRGLLIRFLGRFTKSLTKSWHMYPVGFLFGLGFDTATEIALLVLAGTS
AAAGLPWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSSPVRKIYYNITVTGLSVAVALLIGSVELLGLIANQLGWQ
GPFWDWLGGLDLNTVGFVVVAMFALTWAIALLVWHYGRVEERWTPAPDRTT

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 40535; Mature: 40404

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCC
>Mature Secondary Structure 
ASSQLDRQRSRSAKMNRALTAAEWWRLGLMFAVIVALHLVGWLTVTLLVEPARLSLGGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCC
AFGIGVGLTAYTLGLRHAFDADHIAAIDNTTRKLMSDGHRPLAVGFFFSLGHSTVVFGLA
EEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHCHHHHHHHHH
VMLVTGLKAIVGPVENDSSTLHHYTGLIGTSISGAFLYLIGILNVIVLVGIVRVFAHLRR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDYDEAELEQQLDNRGLLIRFLGRFTKSLTKSWHMYPVGFLFGLGFDTATEIALLVLAGT
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHEECC
SAAAGLPWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSSPVRKIYYNITVTGLSVA
CCCCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHCCHHHHEEEEEEHHHHHH
VALLIGSVELLGLIANQLGWQGPFWDWLGGLDLNTVGFVVVAMFALTWAIALLVWHYGRV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
EERWTPAPDRTT
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]